1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and ALS - Amyotrophic Lateral Sclerosis

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with ALS - Amyotrophic Lateral Sclerosis in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Lee, JD; Woodruff, TM1
Ayata, C; Chen, X; Herisson, F; Kazantsev, AG; Maxwell, MM; Moniot, S; Outeiro, TF; Quinti, L; Rauf, NA; Schwarzschild, MA; Silverman, RB; Steegborn, C; Wales, P; Wang, H; Zuo, F1
Przedborski, S; Vila, M1
Choi, DK; Heinecke, JW; Jackson-Lewis, V; Pennathur, S; Perier, C; Przedborski, S; Teismann, P; Tieu, K; Vila, M; Vonsattel, JP; Wu, DC1
Edwards, RH1
Albers, DS; Andreassen, OA; Beal, MF; Dedeoglu, A; Ferrante, RJ; Klein, AM; Klivenyi, P; Kowall, NW1
Langston, JW; Tanner, CM1
Javitch, JA; Snyder, SH; Uhl, GR1

Reviews

3 review(s) available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and ALS - Amyotrophic Lateral Sclerosis

ArticleYear
Targeting programmed cell death in neurodegenerative diseases.
    Nature reviews. Neuroscience, 2003, Volume: 4, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Dopamine Agents; Humans; Huntington Disease; Models, Biological; Neurodegenerative Diseases; Parkinson Disease

2003
Neural degeneration and the transport of neurotransmitters.
    Annals of neurology, 1993, Volume: 34, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amyotrophic Lateral Sclerosis; Animals; Biological Transport; Cell Membrane; Humans; Nerve Degeneration; Neurotransmitter Agents; Parkinson Disease; Parkinson Disease, Secondary

1993
Do environmental toxins cause Parkinson's disease? A critical review.
    Neurology, 1990, Volume: 40, Issue:10 Suppl 3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Age Factors; Amyotrophic Lateral Sclerosis; Environmental Exposure; Female; Humans; Male; Models, Neurological; Neurotoxins; Pacific Islands; Parkinson Disease; Parkinson Disease, Secondary; Prevalence

1990

Other Studies

5 other study(ies) available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and ALS - Amyotrophic Lateral Sclerosis

ArticleYear
TDP-43 Puts the STING in ALS.
    Trends in neurosciences, 2021, Volume: 44, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amyotrophic Lateral Sclerosis; Bites and Stings; DNA-Binding Proteins; DNA, Mitochondrial; Humans; Membrane Proteins; Nucleotidyltransferases; Signal Transduction

2021
The sirtuin-2 inhibitor AK7 is neuroprotective in models of Parkinson's disease but not amyotrophic lateral sclerosis and cerebral ischemia.
    PloS one, 2015, Volume: 10, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Amyotrophic Lateral Sclerosis; Animals; Benzamides; Brain Ischemia; Cell Line; Disease Models, Animal; Humans; Male; Mice; Neuroprotective Agents; Parkinson Disease; Sirtuin 2; Small Molecule Libraries; Sulfonamides

2015
Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jul-13, Volume: 25, Issue:28

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amyotrophic Lateral Sclerosis; Animals; Brain; Corpus Striatum; Dopamine; Drug Evaluation, Preclinical; Enzyme Induction; Humans; Huntington Disease; Hypochlorous Acid; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine

2005
Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid.
    Experimental neurology, 2001, Volume: 168, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amyotrophic Lateral Sclerosis; Animals; Convulsants; Corpus Striatum; Dopamine; Dopamine Agents; Female; Hazardous Substances; Homovanillic Acid; Male; Mice; Mice, Transgenic; Mitochondria; Nitro Compounds; Propionates; Superoxide Dismutase

2001
Normal MPTP binding in parkinsonian substantial nigra: evidence for extraneuronal toxin conversion in human brain.
    Lancet (London, England), 1985, Apr-27, Volume: 1, Issue:8435

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Amyotrophic Lateral Sclerosis; Autoradiography; Humans; Parkinson Disease; Pyridines; Substantia Nigra

1985