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1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine and Parkinson Disease, Secondary

1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine has been researched along with Parkinson Disease, Secondary in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Block, F; Clement, HW; Grote, C; Sontag, KH; Wesemann, W1
Altagracia, M; Kravzov, J; Rios, C; Rojas, P1
Bédard, PJ; Di Paolo, T; Gagnon, C; Gomez-Mancilla, B1
Herrero, MT; Laguna, J; Luquin, MR; Obeso, JA1
Kuno, S; Mizuta, E; Sasa, M; Yoshida, O; Yoshimura, N1
Hineno, T; Hiratani, K; Kakimoto, Y; Mizobuchi, M1
Samuelsson, EB; Sundström, E1
Camarata, PJ; Chae, H; Ebner, TJ; Haines, SJ; Park, SK; Parker, RG; Turner, DA1
Benazzouz, A; Bioulac, B; Dupont, J; Gross, C1
Alexander, GM; Brainard, L; Gordon, SW; Grothusen, JR; Schwartzman, RJ1
Bachurin, SO; Dubova, LG; Lermontova, NN; Sablin, SO; Solyakov, LS; Tkachenko, SE1
Filion, M; Tremblay, L1
Bédard, PJ; Filion, M; Tremblay, L1
McCrodden, JM; Sullivan, JP; Tipton, KF1
Bédard, PJ; Di Paolo, T; Rouillard, C1

Reviews

1 review(s) available for 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine and Parkinson Disease, Secondary

ArticleYear
The neurotoxicity of MPTP and the relevance to Parkinson's disease.
    Pharmacology & toxicology, 1990, Volume: 67, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Humans; MPTP Poisoning; Parkinson Disease, Secondary

1990

Other Studies

14 other study(ies) available for 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine and Parkinson Disease, Secondary

ArticleYear
Functional studies on monoaminergic transmitter release in parkinsonism.
    Progress in neuro-psychopharmacology & biological psychiatry, 1993, Volume: 17, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Apomorphine; Biogenic Monoamines; Dopamine; Dopamine Agents; Dopamine Antagonists; Hydroxyindoleacetic Acid; Levodopa; Male; Monoamine Oxidase Inhibitors; Parkinson Disease, Secondary; Rats; Rats, Wistar; Stereotyped Behavior; Tryptophan

1993
Amantadine enhances dopamine and serotonin turnover in the MPTP model of Parkinson's disease.
    Proceedings of the Western Pharmacology Society, 1993, Volume: 36

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amantadine; Animals; Brain Chemistry; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Parkinson Disease, Secondary; Probenecid; Serotonin

1993
Chronic CY 208-243 treatment of MPTP-monkeys causes regional changes of dopamine and GABAA receptors.
    Neuroscience letters, 1993, Nov-26, Volume: 163, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Behavior, Animal; Brain Chemistry; Dopamine; Dopamine Agents; Dopamine D2 Receptor Antagonists; Female; GTP-Binding Proteins; Indoles; Macaca fascicularis; Neostriatum; Ovariectomy; Parkinson Disease, Secondary; Phenanthridines; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, GABA-A

1993
Behavioral tolerance to repeated apomorphine administration in parkinsonian monkeys.
    Journal of the neurological sciences, 1993, Volume: 114, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Behavior, Animal; Dopamine; Dopamine Agents; Drug Tolerance; Female; Macaca fascicularis; Male; MPTP Poisoning; Oxazines; Parkinson Disease, Secondary; Psychomotor Performance

1993
The dopamine D1 receptor agonist SKF 38393 suppresses detrusor hyperreflexia in the monkey with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Neuropharmacology, 1993, Volume: 32, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Dopamine Agents; Ergolines; Macaca fascicularis; Male; Parkinson Disease, Secondary; Quinpirole; Reflex; Urinary Bladder; Urination

1993
Increase of plasma adrenocorticotrophin and cortisol in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated dogs.
    Brain research, 1993, May-28, Volume: 612, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Circadian Rhythm; Dogs; Dopamine Agents; Hydrocortisone; Hypothalamus; Male; Osmolar Concentration; Parkinson Disease, Secondary; Pituitary Gland

1993
Comparison of key steps in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in rodents.
    Pharmacology & toxicology, 1997, Volume: 81, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain; Dopamine; Lactic Acid; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Norepinephrine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Synaptosomes

1997
Effects of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-induced hemiparkinsonism on the kinematics of a two-dimensional,multijoint arm movement in the rhesus monkey.
    Neuroscience, 1992, Volume: 48, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Arm; Behavior, Animal; Carbidopa; Female; Levodopa; Macaca mulatta; Male; Movement; Parkinson Disease, Secondary; Reaction Time; Substantia Nigra; Tyrosine 3-Monooxygenase

1992
MPTP induced hemiparkinsonism in monkeys: behavioral, mechanographic, electromyographic and immunohistochemical studies.
    Experimental brain research, 1992, Volume: 90, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Dopamine Agents; Electromyography; Immunohistochemistry; Kinetics; Macaca mulatta; Muscles; Parkinson Disease, Secondary

1992
Changes in brain catecholamines and dopamine uptake sites at different stages of MPTP parkinsonism in monkeys.
    Brain research, 1992, Aug-21, Volume: 588, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Chemistry; Catecholamines; Dopamine; Dopamine Agents; Levodopa; Macaca fascicularis; Male; Mazindol; Parkinson Disease, Secondary; Receptors, Dopamine

1992
Molecular basis of discrepancies in neurotoxic properties among 1-methyl-4-aryl-1,2,3,6-tetrahydropyridines.
    Molecular and chemical neuropathology, 1992, Volume: 17, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain Chemistry; Dopamine; Dopamine Agents; Guinea Pigs; In Vitro Techniques; Kinetics; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Monoamine Oxidase; MPTP Poisoning; Nerve Degeneration; Neurons; Norepinephrine; Parkinson Disease, Secondary; Structure-Activity Relationship; Synaptosomes

1992
Abnormal spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism.
    Brain research, 1991, Apr-26, Volume: 547, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Basal Ganglia; Dopamine Agents; Electrophysiology; Female; Globus Pallidus; Macaca fascicularis; Medulla Oblongata; Neurons; Parkinson Disease, Secondary

1991
Effects of dopamine agonists on the spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism.
    Brain research, 1991, Apr-26, Volume: 547, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Basal Ganglia; Dopamine Agents; Electrophysiology; Globus Pallidus; Macaca fascicularis; Motor Activity; Neurons; Parkinson Disease, Secondary; Phenethylamines

1991
Effects of chronic treatment of MPTP monkeys with bromocriptine alone or in combination with SKF 38393.
    European journal of pharmacology, 1990, Aug-28, Volume: 185, Issue:2-3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Bromocriptine; Dopamine; Female; Homovanillic Acid; Kinetics; Levodopa; Macaca fascicularis; Motor Activity; MPTP Poisoning; Parkinson Disease, Secondary; Receptors, Dopamine; Spiperone

1990