1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine has been researched along with MPTP Neurotoxicity Syndrome in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.00) | 18.7374 |
| 1990's | 20 (80.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ho, G; Kng, YL; Kumar, S; Zhang, C; Zhuo, L | 1 |
| Chan, HH; Ho, G; Ke, Z; Kng, YL; Kumar, S; Suhaimi, NA; Zhang, Y; Zhuo, L | 1 |
| Lynch, WP; Ourednik, J; Ourednik, V; Schachner, M; Snyder, EY | 1 |
| Steindler, DA | 1 |
| Agnati, LF; Chadi, G; David, G; Fuxe, K; Pettersson, R; Tinner, B | 1 |
| Bernocchi, G; Gerzeli, G; Scherini, E; Vignola, C | 1 |
| De Natale, G; Desole, MS; Enrico, P; Esposito, G; Fresu, L; Miele, E; Miele, M; Migheli, R | 1 |
| Chia, LG; Kuo, JS; Lee, EH; Yang, YL | 1 |
| Herrero, MT; Laguna, J; Luquin, MR; Obeso, JA | 1 |
| Otto, D; Unsicker, K | 1 |
| Del Zompo, M; Gessa, GL; Piccardi, MP; Quartu, M; Ruiu, S; Vaccari, A | 1 |
| Hasegawa, E; Murai, Y; Oishi, T | 1 |
| Samuelsson, EB; Sundström, E | 1 |
| Chen, XL; Gupta, M | 1 |
| Bachurin, SO; Dubova, LG; Lermontova, NN; Sablin, SO; Solyakov, LS; Tkachenko, SE | 1 |
| Lee, EH; Lin, WR; Liu, SP; Lu, KT | 1 |
| Hallberg, A; Nilsson, K; Pileblad, E; Tunek, A | 1 |
| Hadjiconstantinou, M; Neff, NH | 1 |
| Horng, J; Krishna, G; Kutty, RK; Santostasi, G | 1 |
| Gibb, WR; Jackson, EA; Jenner, P; Marsden, CD; Nomoto, M; Rose, S | 1 |
| McCrodden, JM; Sullivan, JP; Tipton, KF | 1 |
| Bédard, PJ; Di Paolo, T; Rouillard, C | 1 |
| Carr, LA; Rowell, PP | 1 |
| Fukui, Y; Nagatsu, T; Naoi, M; Ohashi, M; Takahashi, T; Umemura, T; Yasue, T | 1 |
| Iacono, RP; Sandyk, R | 1 |
2 review(s) available for 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
The neurotoxicity of MPTP and the relevance to Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Humans; MPTP Poisoning; Parkinson Disease, Secondary | 1990 |
The neurotoxicity of MPTP and its relationship to the pathophysiology of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Humans; MPTP Poisoning; Nervous System; Nervous System Diseases; Parkinson Disease | 1989 |
23 other study(ies) available for 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
Molecular imaging reveals a correlation between 2'-CH3-MPTP-induced neonatal neurotoxicity and dopaminergic neurodegeneration in adult transgenic mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Animals, Newborn; Brain; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gliosis; Image Cytometry; Immunohistochemistry; Male; Mice; Mice, Transgenic; Microscopy, Fluorescence; MPTP Poisoning; Nerve Degeneration; Neurons; Substantia Nigra; Time; Time Factors | 2008 |
Imidazolium salt (DBZIM) reduces gliosis in mice treated with neurotoxicant 2'-CH(3) -MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Dopamine; Dopamine Antagonists; Eye; Glial Fibrillary Acidic Protein; Gliosis; Green Fluorescent Proteins; Imidazoles; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Transgenic; MPTP Poisoning; Neostriatum; Neurons; Ophthalmoscopy; Retina; Superoxide Dismutase | 2011 |
Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Cell Count; Cell Survival; Dextroamphetamine; Female; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Regeneration; Neurons; Parkinsonian Disorders; Recovery of Function; Reference Values; Signal Transduction; Stem Cell Transplantation; Stem Cells; Substantia Nigra; Tyrosine 3-Monooxygenase | 2002 |
Neural stem cells, scaffolds, and chaperones.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biocompatible Materials; Cell Survival; Dextroamphetamine; Female; Hypoxia-Ischemia, Brain; Male; Mice; Mice, Inbred C57BL; Molecular Chaperones; MPTP Poisoning; Nerve Degeneration; Nerve Regeneration; Neural Pathways; Neurons; Parkinsonian Disorders; Polyglycolic Acid; Prostheses and Implants; Recovery of Function; Signal Transduction; Stem Cell Transplantation; Stem Cells; Substantia Nigra; Textiles; Tyrosine 3-Monooxygenase | 2002 |
On the regional distribution of heparan sulfate proteoglycan immunoreactivity in the rat brain.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antibodies, Monoclonal; Astrocytes; Brain Chemistry; Dopamine Agents; Epitopes; Fibroblast Growth Factor 2; Fluorescent Antibody Technique; Heparitin Sulfate; Immunohistochemistry; Male; MPTP Poisoning; Rats; Rats, Sprague-Dawley; Spectrophotometry, Infrared; Tyrosine 3-Monooxygenase | 1994 |
Neuroprotective effects of alpha-dihydroergocryptine against damages in the substantia nigra caused by severe treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Axons; Brain Diseases; Dihydroergotoxine; Dopamine Agents; Eosine Yellowish-(YS); Glial Fibrillary Acidic Protein; Hematoxylin; Macaca fascicularis; Male; MPTP Poisoning; Neurofilament Proteins; Staining and Labeling; Substantia Nigra | 1993 |
Correlation between 1-methyl-4-phenylpyridinium ion (MPP+) levels, ascorbic acid oxidation and glutathione levels in the striatal synaptosomes of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated rat.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Glutathione; Male; MPTP Poisoning; Nerve Endings; Oxidation-Reduction; Pyridinium Compounds; Rats; Rats, Wistar; Synaptosomes; Uric Acid | 1993 |
Interactions among deprenyl, clorgyline and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on catecholamines in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain Chemistry; Catecholamines; Clorgyline; Dopamine; Dopamine Agents; Drug Interactions; Hippocampus; Male; Mice; Mice, Inbred BALB C; MPTP Poisoning; Neostriatum; Norepinephrine; Selegiline; Serotonin | 1994 |
Behavioral tolerance to repeated apomorphine administration in parkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Behavior, Animal; Dopamine; Dopamine Agents; Drug Tolerance; Female; Macaca fascicularis; Male; MPTP Poisoning; Oxazines; Parkinson Disease, Secondary; Psychomotor Performance | 1993 |
FGF-2-mediated protection of cultured mesencephalic dopaminergic neurons against MPTP and MPP+: specificity and impact of culture conditions, non-dopaminergic neurons, and astroglial cells.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Astrocytes; Cells, Cultured; Dopamine; Dopamine Agents; Enzyme-Linked Immunosorbent Assay; Female; Fibroblast Growth Factor 2; Glial Fibrillary Acidic Protein; Immunohistochemistry; Mesencephalon; MPTP Poisoning; Neurites; Neurofilament Proteins; Neurons; Pregnancy; Pyridinium Compounds; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase | 1993 |
Selective MPP+ uptake into synaptic dopamine vesicles: possible involvement in MPTP neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Biomarkers; Brain; Corpus Striatum; Dopamine; Dopamine Agents; In Vitro Techniques; Male; Mice; Microscopy, Electron; MPTP Poisoning; Nervous System Diseases; Pyridinium Compounds; Synaptic Vesicles; Tetrabenazine | 1993 |
Sulfhydryl drugs reduce neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Cysteamine; Dimercaprol; Dopamine; Dopamine Agents; Glutathione; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Degeneration; Nervous System Diseases; Pyridinium Compounds; Sulfhydryl Compounds | 1993 |
Comparison of key steps in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in rodents.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain; Dopamine; Lactic Acid; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Norepinephrine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Synaptosomes | 1997 |
Neurotoxicity of an MPTP analogue, 2'CH3-MPTP, on monoaminergic systems in the mouse brain.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Dopamine Agents; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neurons; Neurotoxins; Organ Specificity; Tyrosine 3-Monooxygenase | 1992 |
Molecular basis of discrepancies in neurotoxic properties among 1-methyl-4-aryl-1,2,3,6-tetrahydropyridines.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain Chemistry; Dopamine; Dopamine Agents; Guinea Pigs; In Vitro Techniques; Kinetics; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Monoamine Oxidase; MPTP Poisoning; Nerve Degeneration; Neurons; Norepinephrine; Parkinson Disease, Secondary; Structure-Activity Relationship; Synaptosomes | 1992 |
Comparative studies of the neurotoxicity of MPTP in rats of different ages.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Behavior, Animal; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Dopamine beta-Hydroxylase; Immunohistochemistry; Male; Motor Activity; MPTP Poisoning; Nervous System Diseases; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Tyrosine 3-Monooxygenase | 1992 |
Investigation of the possible dopaminergic toxicity of 1-methyl-3-phenyl-1,2,3,6-tetrahydropyridine, an isomer to the neurotoxin MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; In Vitro Techniques; Isomerism; Limbic System; Magnetic Resonance Spectroscopy; Male; Mice; Mitochondria, Liver; Monoamine Oxidase; MPTP Poisoning; Rats; Rats, Inbred Strains | 1991 |
Differential recovery of dopamine synthetic enzymes following MPTP and the consequences of GM1 ganglioside treatment.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; G(M1) Ganglioside; Male; Mice; MPTP Poisoning; Nervous System Diseases; Tyrosine 3-Monooxygenase | 1990 |
MPTP-induced ATP depletion and cell death in neuroblastoma X glioma hybrid NG 108-15 cells: protection by glucose and sensitization by tetraphenylborate.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenine Nucleotides; Adenosine Triphosphate; Cell Survival; Dose-Response Relationship, Drug; Glioma; Glucose; Humans; L-Lactate Dehydrogenase; MPTP Poisoning; Neuroblastoma; Neurons; Tetraphenylborate; Tumor Cells, Cultured | 1991 |
1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-methyl-MPTP) is less neurotoxic than MPTP in the common marmoset.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Biogenic Amines; Brain Chemistry; Callitrichinae; Caudate Nucleus; Dopamine; Female; Male; MPTP Poisoning; Nervous System Diseases; Putamen; Substantia Nigra; Synaptosomes | 1990 |
Effects of chronic treatment of MPTP monkeys with bromocriptine alone or in combination with SKF 38393.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Bromocriptine; Dopamine; Female; Homovanillic Acid; Kinetics; Levodopa; Macaca fascicularis; Motor Activity; MPTP Poisoning; Parkinson Disease, Secondary; Receptors, Dopamine; Spiperone | 1990 |
Attenuation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity by tobacco smoke.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Nervous System Diseases; Smoking | 1990 |
Cytotoxic effect of 1-methyl-4-phenylpyridinium ion on human melanoma cell lines, HMV-II and SK-MEL-44, is dependent on the melanin contents and caused by inhibition of mitochondrial electron transport.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Cell Line; Cell Survival; Colony-Forming Units Assay; Electron Transport; Formazans; Humans; Melanins; Melanoma; Mitochondria; MPTP Poisoning; Oxidation-Reduction; Pyridinium Compounds; Tumor Cells, Cultured | 1990 |