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1-methyl-3-isobutylxanthine and Testicular Neoplasms

1-methyl-3-isobutylxanthine has been researched along with Testicular Neoplasms in 6 studies

1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.

Testicular Neoplasms: Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.

Research Excerpts

ExcerptRelevanceReference
"When pregnenolone metabolism was inhibited, basal pregnenolone production was 26."1.26Lutropin-dependent protein phosphorylation and steroidogenesis in rat tumour Leydig cells. ( Bakker, GH; Hoogerbrugge, JW; Rommerts, FF; van der Molen, HJ, 1981)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Panesar, NS1
Chan, KW1
Bakker, GH2
Hoogerbrugge, JW2
Rommerts, FF2
van der Molen, HJ2
Rebois, RV1
Fishman, PH1
Pereira, ME1
Segaloff, DL1
Ascoli, M1
Eckstein, F1
McMurray, CT1
Devi, L1
Calavetta, L1
Douglass, JO1

Other Studies

6 other studies available for 1-methyl-3-isobutylxanthine and Testicular Neoplasms

ArticleYear
Low temperature blocks the stimulatory effect of human chorionic gonadotropin on steroidogenic acute regulatory protein mRNA and testosterone production but not cyclic adenosine monophosphate in mouse Leydig tumor cells.
    Metabolism: clinical and experimental, 2004, Volume: 53, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cell Line; Chorionic Gonadotropin; Cold Tem

2004
Lutropin-dependent protein phosphorylation and steroidogenesis in rat tumour Leydig cells.
    The Biochemical journal, 1981, Aug-15, Volume: 198, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; In Vitro Techniques; Kinetics; Leydig Cells; Luteinizing Hormo

1981
Down-regulation of gonadotropin receptors in a murine Leydig tumor cell line.
    The Journal of biological chemistry, 1984, Mar-10, Volume: 259, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Line; Chorionic Gonadotropin; Cyclic AMP; Cy

1984
Inhibition of choriogonadotropin-activated steroidogenesis in cultured Leydig tumor cells by the Rp diastereoisomer of adenosine 3',5'-cyclic phosphorothioate.
    The Journal of biological chemistry, 1987, May-05, Volume: 262, Issue:13

    Topics: 1-Methyl-3-isobutylxanthine; Affinity Labels; Animals; Chorionic Gonadotropin; Cyclic AMP; Dose-Resp

1987
Regulated expression of the prodynorphin gene in the R2C Leydig tumor cell line.
    Endocrinology, 1989, Volume: 124, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Northern; Cy

1989
Lutropin stimulates de novo synthesis of short-lived proteins required for lutropin-dependent steroid production in tumour Leydig cells.
    Journal of steroid biochemistry, 1985, Volume: 22, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cycloheximide; Half-Life; Leydig Cell Tumor; Leydig Cells; Lut

1985