1-methyl-3-isobutylxanthine has been researched along with Testicular Neoplasms in 6 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Testicular Neoplasms: Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When pregnenolone metabolism was inhibited, basal pregnenolone production was 26." | 1.26 | Lutropin-dependent protein phosphorylation and steroidogenesis in rat tumour Leydig cells. ( Bakker, GH; Hoogerbrugge, JW; Rommerts, FF; van der Molen, HJ, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Panesar, NS | 1 |
| Chan, KW | 1 |
| Bakker, GH | 2 |
| Hoogerbrugge, JW | 2 |
| Rommerts, FF | 2 |
| van der Molen, HJ | 2 |
| Rebois, RV | 1 |
| Fishman, PH | 1 |
| Pereira, ME | 1 |
| Segaloff, DL | 1 |
| Ascoli, M | 1 |
| Eckstein, F | 1 |
| McMurray, CT | 1 |
| Devi, L | 1 |
| Calavetta, L | 1 |
| Douglass, JO | 1 |
6 other studies available for 1-methyl-3-isobutylxanthine and Testicular Neoplasms
| Article | Year |
|---|---|
Low temperature blocks the stimulatory effect of human chorionic gonadotropin on steroidogenic acute regulatory protein mRNA and testosterone production but not cyclic adenosine monophosphate in mouse Leydig tumor cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cell Line; Chorionic Gonadotropin; Cold Tem | 2004 |
Lutropin-dependent protein phosphorylation and steroidogenesis in rat tumour Leydig cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; In Vitro Techniques; Kinetics; Leydig Cells; Luteinizing Hormo | 1981 |
Down-regulation of gonadotropin receptors in a murine Leydig tumor cell line.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Line; Chorionic Gonadotropin; Cyclic AMP; Cy | 1984 |
Inhibition of choriogonadotropin-activated steroidogenesis in cultured Leydig tumor cells by the Rp diastereoisomer of adenosine 3',5'-cyclic phosphorothioate.
Topics: 1-Methyl-3-isobutylxanthine; Affinity Labels; Animals; Chorionic Gonadotropin; Cyclic AMP; Dose-Resp | 1987 |
Regulated expression of the prodynorphin gene in the R2C Leydig tumor cell line.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Northern; Cy | 1989 |
Lutropin stimulates de novo synthesis of short-lived proteins required for lutropin-dependent steroid production in tumour Leydig cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cycloheximide; Half-Life; Leydig Cell Tumor; Leydig Cells; Lut | 1985 |