1-methyl-3-isobutylxanthine has been researched along with Skin Neoplasms in 8 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Skin Neoplasms: Tumors or cancer of the SKIN.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, WR | 1 |
| Shen, SC | 1 |
| Wu, PR | 1 |
| Chou, CL | 1 |
| Shih, YH | 1 |
| Yeh, CM | 1 |
| Yeh, KT | 1 |
| Jiang, MC | 1 |
| Perchellet, JP | 2 |
| Boutwell, RK | 2 |
| Carsberg, CJ | 1 |
| Warenius, HM | 1 |
| Friedmann, PS | 2 |
| Hill, HZ | 1 |
| Li, W | 1 |
| Xin, P | 1 |
| Mitchell, DL | 1 |
| Wren, F | 1 |
| Buffey, J | 1 |
| Macneil, S | 1 |
| Halaban, R | 1 |
| Ghosh, S | 1 |
| Duray, P | 1 |
| Kirkwood, JM | 1 |
| Lerner, AB | 1 |
| Tsutsui, M | 1 |
| Iizuka, H | 1 |
| Ohkawara, A | 1 |
| Adachi, K | 1 |
| Kanzaki, T | 1 |
1 review available for 1-methyl-3-isobutylxanthine and Skin Neoplasms
| Article | Year |
|---|---|
Melanin: a two edged sword?
Topics: 1-Methyl-3-isobutylxanthine; Animals; Disease Susceptibility; DNA Damage; Humans; Melanins; Melanocy | 1997 |
7 other studies available for 1-methyl-3-isobutylxanthine and Skin Neoplasms
| Article | Year |
|---|---|
CSE1L Links cAMP/PKA and Ras/ERK pathways and regulates the expressions and phosphorylations of ERK1/2, CREB, and MITF in melanoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Aged; Aged, 80 and over; Animals; Cell Line, Tumor; Cellular Apoptosis | 2016 |
Effects of 3-isobutyl-1-methylxanthine and cyclic nucleotides on the biochemical processes linked to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 1-Methyl-3-isobutylxanthine; Administration, Topical; Animals; Cocarcinogenesis; Cyclic AMP; Cyclic | 1981 |
Comparison of the effects of 3-isobutyl-1-methylxanthine and adenosine cyclic 3':5'-monophosphate on the induction of skin tumors by the initiation-promotion protocol and by the complete carcinogenesis process.
Topics: 1-Methyl-3-isobutylxanthine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclic AMP; DNA; Female; In | 1982 |
Ultraviolet radiation-induced melanogenesis in human melanocytes. Effects of modulating protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Diglycerides; Enzyme Induction; Humans; Indoles; In | 1994 |
Alpha-MSH causes a small rise in cAMP but has no effect on basal or ultraviolet-stimulated melanogenesis in human melanocytes.
Topics: 1-Methyl-3-isobutylxanthine; Child; Child, Preschool; Colforsin; Cyclic AMP; Humans; Male; Melanins; | 1990 |
Human melanocytes cultured from nevi and melanomas.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Cell Division; Cell Separation; Cells, Cultured; Child; Ch | 1986 |
Adenylate cyclase system of human trichilemmoma cell line.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Cell Line; Epinephrine; Hair Diseases; Histamine; Hu | 1987 |