1-methyl-3-isobutylxanthine has been researched along with Pregnancy in 86 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our results show that the use of the current version of the SPOM system may have adverse effects on oocytes and blastocysts calling for optimized protocols for improving oocyte competence." | 1.51 | Simulated physiological oocyte maturation has side effects on bovine oocytes and embryos. ( Callesen, H; Fontes, PK; Hyttel, P; Kadarmideen, HN; Nogueira, MFG; Pedersen, HS; Pihl, M; Razza, EM; Stroebech, L, 2019) |
| " Insulin responsiveness of the lipolytic and lipogenic pathways was analyzed by dose-response experiments, giving evidence for the involvement of improved insulin responsiveness in the enhanced lipogenic and reduced lipolytic activities of adipocytes in early pregnancy." | 1.32 | Fat accumulation in the rat during early pregnancy is modulated by enhanced insulin responsiveness. ( Cacho, J; Crespo-Solans, MD; del Campo, S; Herrera, E; Ramos, MP, 2003) |
| "Both carbachol effects were reproduced by oxotremorine, whereas pilocarpine (a partial muscarinic agonist) failed to induce any decrease in cyclic AMP accumulation and concurrently was unable to stimulate the generation of inositol phosphates." | 1.28 | Prostaglandins and muscarinic agonists induce cyclic AMP attenuation by two distinct mechanisms in the pregnant-rat myometrium. Interaction between cyclic AMP and Ca2+ signals. ( Goureau, O; Harbon, S; Tanfin, Z, 1990) |
| " The ATPase log dose-response curve was linear between approximately 12." | 1.28 | Enzyme activation of human prolactin: a potential basis for a bioassay. ( Bertrand, PV; Ryle, M, 1989) |
| "Monensin prevented the increase in thromboplastin activity at 68 hr as well as at 90-96 hr." | 1.27 | Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo. ( Dalaker, K; Prydz, H, 1986) |
| "These retinoid-treated choriocarcinoma cells remained responsive to 8BrcAMP or compounds that increase intracellular cAMP concentrations and to BrdUrd; the production to PS beta G and hCG was greatly stimulated by 8BrcAMP, cholera toxin, or MIX, and the production of hCG and hCG alpha was greatly inhibited by BrdUrd." | 1.26 | Effects of retinoic acid on differentiation of choriocarcinoma cells in vitro. ( Chou, JY, 1982) |
| " IBMX by itself, stimulated ornithine decarboxylase (ODC) activity in a dose-response fashion; but the IBMX at concentrations up to 1 mM had no effect on the magnitude of the prolactin-stimulated ODC activity." | 1.26 | Effect of 3-isobutyl-1-methylxanthine on prolactin actions on RNA synthesis, casein synthesis, lipid synthesis and ornithine decarboxylase activity in mouse mammary gland explants. ( Rillema, JA; Wing, LY, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (40.70) | 18.7374 |
| 1990's | 30 (34.88) | 18.2507 |
| 2000's | 14 (16.28) | 29.6817 |
| 2010's | 6 (6.98) | 24.3611 |
| 2020's | 1 (1.16) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, J | 1 |
| Hammoud, B | 1 |
| Li, C | 1 |
| Ridler, A | 1 |
| Yau, D | 1 |
| Kim, J | 1 |
| Won, KJ | 1 |
| Stanley, CA | 1 |
| Hoshi, T | 1 |
| Stanescu, DE | 1 |
| Razza, EM | 2 |
| Sudano, MJ | 1 |
| Fontes, PK | 2 |
| Franchi, FF | 1 |
| Belaz, KRA | 1 |
| Santos, PH | 1 |
| Castilho, ACS | 1 |
| Rocha, DFO | 1 |
| Eberlin, MN | 1 |
| Machado, MF | 1 |
| Nogueira, MFG | 2 |
| Pedersen, HS | 1 |
| Stroebech, L | 1 |
| Kadarmideen, HN | 1 |
| Callesen, H | 1 |
| Pihl, M | 1 |
| Hyttel, P | 1 |
| Balazi, A | 1 |
| Sirotkin, AV | 2 |
| Pivko, J | 1 |
| Chrenek, P | 2 |
| Chadio, S | 1 |
| Xylouri, E | 1 |
| Fotopouloy, H | 1 |
| Albuz, FK | 1 |
| Sasseville, M | 1 |
| Lane, M | 1 |
| Armstrong, DT | 2 |
| Thompson, JG | 1 |
| Gilchrist, RB | 1 |
| Micholt, E | 1 |
| Jans, D | 1 |
| Callewaert, G | 1 |
| Bartic, C | 1 |
| Lammertyn, J | 1 |
| Nicolai, B | 1 |
| Baamonde, C | 1 |
| Lumbreras, MA | 1 |
| MartInez-Cué, C | 1 |
| Vallina, IF | 1 |
| Flórez, J | 1 |
| Dierssen, M | 1 |
| Gonzales, LW | 2 |
| Guttentag, SH | 1 |
| Wade, KC | 1 |
| Postle, AD | 1 |
| Ballard, PL | 2 |
| Mertz, HL | 1 |
| Liu, J | 1 |
| Valego, NK | 1 |
| Stallings, SP | 1 |
| Figueroa, JP | 1 |
| Rose, JC | 1 |
| Ramos, MP | 1 |
| Crespo-Solans, MD | 1 |
| del Campo, S | 1 |
| Cacho, J | 1 |
| Herrera, E | 1 |
| Phillips, AW | 1 |
| Zhang, P | 1 |
| Truckenmiller, ME | 1 |
| Keir, SD | 1 |
| Bouvier, M | 1 |
| Tornatore, C | 1 |
| Freed, WJ | 1 |
| Zhou, F | 1 |
| Tanaka, K | 1 |
| Soares, MJ | 1 |
| You, G | 1 |
| Williams, JM | 1 |
| White, CR | 1 |
| Chang, MM | 1 |
| Injeti, ER | 1 |
| Zhang, L | 1 |
| Pearce, WJ | 1 |
| Ola, SI | 1 |
| Wang, Q | 1 |
| Ai, JS | 1 |
| Yin, S | 1 |
| Liang, CG | 1 |
| Chen, DY | 1 |
| Sun, QY | 1 |
| Flint, DJ | 1 |
| Binart, N | 1 |
| Boumard, S | 1 |
| Kopchick, JJ | 1 |
| Kelly, P | 1 |
| Yen, BL | 1 |
| Chien, CC | 1 |
| Chen, YC | 1 |
| Chen, JT | 1 |
| Huang, JS | 1 |
| Lee, FK | 1 |
| Huang, HI | 1 |
| Perry, JW | 1 |
| Oka, T | 1 |
| Peck, WA | 1 |
| Kohler, G | 1 |
| Ying, SY | 1 |
| Ling, N | 1 |
| Böhlen, P | 1 |
| Guillemin, R | 1 |
| Reiher, H | 1 |
| Woltanski, P | 1 |
| Hahn, HJ | 2 |
| Beyer, C | 1 |
| Canchola, E | 1 |
| Chou, JY | 2 |
| Rillema, JA | 3 |
| Wing, LY | 2 |
| Greene, RM | 1 |
| MacAndrew, VI | 1 |
| Lloyd, MR | 1 |
| Cameron, CM | 1 |
| Brenneman, DE | 1 |
| Warren, D | 1 |
| Hong, SL | 1 |
| Dalaker, K | 2 |
| Prydz, H | 2 |
| Ziegler, B | 1 |
| Kohnert, KD | 1 |
| Noack, S | 1 |
| Kaplan, SA | 1 |
| Barrett, CT | 1 |
| Scott, ML | 1 |
| Whitson, RH | 1 |
| Lye, SJ | 1 |
| Challis, JR | 1 |
| Shemesh, M | 3 |
| Hansel, W | 3 |
| Strauss, JF | 3 |
| Tashima, Y | 1 |
| Mizunuma, H | 1 |
| Shima, H | 1 |
| Kobayashi, R | 1 |
| Tanaka, S | 1 |
| Maeda, N | 1 |
| Kumegawa, M | 1 |
| Telfer, JF | 1 |
| Green, CD | 1 |
| Zhu, M | 1 |
| Hirayama, K | 1 |
| Kapatos, G | 1 |
| Dingemanse, MA | 1 |
| de Boer, PA | 1 |
| Moorman, AF | 1 |
| Charles, R | 1 |
| Lamers, WH | 1 |
| Shaul, PW | 1 |
| Wells, LB | 1 |
| Vesce, F | 1 |
| Biondi, C | 1 |
| Ferretti, ME | 1 |
| Pareschi, MC | 1 |
| Buzzi, M | 1 |
| Colamussi, ML | 1 |
| Bruhn, TO | 1 |
| Rondeel, JM | 1 |
| Bolduc, TG | 1 |
| Luo, LG | 1 |
| Jackson, IM | 1 |
| Shim, C | 1 |
| Kwon, HB | 1 |
| Kim, K | 1 |
| Vignery, A | 1 |
| McCarthy, TL | 1 |
| Gillis, C | 1 |
| Jonzon, B | 1 |
| Haegerstrand, A | 1 |
| Dienhart, MK | 1 |
| O'Brien, MJ | 1 |
| Downs, SM | 1 |
| Wegner, CC | 1 |
| Zhou, X | 1 |
| Ding, ZM | 1 |
| Kuo, MT | 1 |
| Carson, DD | 1 |
| Jobe, AH | 1 |
| Ikegami, M | 1 |
| Padbury, J | 1 |
| Polk, DH | 1 |
| Korirnilli, A | 1 |
| Grealy, M | 1 |
| Glynn, MA | 1 |
| Sreenan, JM | 1 |
| Palejwala, S | 1 |
| Stein, D | 1 |
| Wojtczuk, A | 1 |
| Weiss, G | 1 |
| Goldsmith, LT | 1 |
| Wiersma, A | 1 |
| Hirsch, B | 1 |
| Tsafriri, A | 1 |
| Hanssen, RG | 1 |
| Van de Kant, M | 1 |
| Kloosterboer, HJ | 1 |
| Conti, M | 1 |
| Hsueh, AJ | 1 |
| Weinhaus, AJ | 1 |
| Bhagroo, NV | 1 |
| Brelje, TC | 1 |
| Sorenson, RL | 1 |
| Guo, Z | 1 |
| Du, X | 1 |
| Iacovitti, L | 1 |
| Stocco, CO | 1 |
| Deis, RP | 1 |
| Lu, CC | 1 |
| Chen, JJ | 1 |
| Tsai, SC | 1 |
| Chien, EJ | 1 |
| Chien, CH | 1 |
| Wang, PS | 1 |
| Vedernikov, YP | 1 |
| Syal, AS | 1 |
| Okawa, T | 1 |
| Jain, V | 1 |
| Saade, GR | 1 |
| Garfield, RE | 1 |
| Teunissen, CE | 1 |
| Steinbusch, HW | 1 |
| Axer, H | 1 |
| Stacker, SA | 1 |
| Runting, AS | 1 |
| Caesar, C | 1 |
| Vitali, A | 1 |
| Lackmann, M | 1 |
| Chang, J | 1 |
| Ward, L | 1 |
| Wilks, AF | 1 |
| Yu, J | 1 |
| Hecht, NB | 1 |
| Schultz, RM | 1 |
| Wango, EO | 1 |
| Heap, RB | 1 |
| Wooding, FB | 1 |
| Hausman, GJ | 1 |
| Reviriego, J | 1 |
| Alonso, MJ | 1 |
| Ibañez, C | 1 |
| Marín, J | 1 |
| Bliss, CR | 1 |
| Wiedenkeller, DE | 1 |
| Sharp, GW | 1 |
| Goureau, O | 1 |
| Tanfin, Z | 1 |
| Harbon, S | 1 |
| Catella, F | 1 |
| Lawson, J | 1 |
| Braden, G | 1 |
| Fitzgerald, DJ | 1 |
| Shipp, E | 1 |
| FitzGerald, GA | 1 |
| Jones, RE | 1 |
| Defeo-Jones, D | 1 |
| McAvoy, EM | 1 |
| Vuocolo, GA | 1 |
| Wegrzyn, RJ | 1 |
| Haskell, KM | 1 |
| Oliff, A | 1 |
| Homa, ST | 1 |
| Webster, SD | 1 |
| Russell, RK | 1 |
| Yee, GM | 1 |
| Kennedy, TG | 1 |
| Chartrel, N | 1 |
| Tonon, MC | 1 |
| Vaudry, H | 1 |
| Conlon, JM | 1 |
| Lee, QP | 1 |
| Yang, HY | 1 |
| Namkung, MJ | 1 |
| Juchau, MR | 1 |
| Tehrani, MH | 1 |
| Bittles, AH | 1 |
| Thomas, PJ | 1 |
| Reddoch, RB | 1 |
| Pelletier, RM | 1 |
| Barbe, GJ | 1 |
| Chabot, MC | 1 |
| Chepenik, KP | 1 |
| Handwerger, S | 2 |
| Harman, I | 2 |
| Costello, A | 2 |
| Markoff, E | 1 |
| Sane, A | 1 |
| Wince, LC | 1 |
| Hugman, LE | 1 |
| Chen, WY | 1 |
| Robbins, RK | 1 |
| Brenner, GM | 1 |
| Shore, LS | 2 |
| Izhar, M | 1 |
| Brown, DL | 1 |
| Harris, DM | 1 |
| Vernon, RG | 1 |
| Finley, E | 1 |
| Hilf, G | 2 |
| Merz, WE | 2 |
| Ryle, M | 1 |
| Bertrand, PV | 1 |
| Lahav, M | 1 |
| Davis, JS | 1 |
| Rennert, H | 1 |
| Tonkowicz, PA | 1 |
| Poisner, AM | 1 |
86 other studies available for 1-methyl-3-isobutylxanthine and Pregnancy
| Article | Year |
|---|---|
Decreased KATP Channel Activity Contributes to the Low Glucose Threshold for Insulin Secretion of Rat Neonatal Islets.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acids, Cyclic; Animals; Animals, Newborn; Cells, Cultured; Embryo | 2021 |
Treatment with cyclic adenosine monophosphate modulators prior to in vitro maturation alters the lipid composition and transcript profile of bovine cumulus-oocyte complexes and blastocysts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blastocyst; Cattle; Colforsin; Cumulus Cells; Cyclic AMP; Embr | 2018 |
Simulated physiological oocyte maturation has side effects on bovine oocytes and embryos.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blastocyst; Cattle; Colforsin; Cumulus Cells; Embryonic Develo | 2019 |
Effect of oxytocin, IBMX and dbcAMP on rabbit ovarian follicles.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Proliferation; Cyclic AMP-Dependent Protein | 2014 |
Phosphodiesterase inhibitor 3-isobutyl-methyl-xanthine stimulates reproduction in rabbit females.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Body Weight; Chorionic Gonadotropin; Female; Litter Size; Phos | 2010 |
Simulated physiological oocyte maturation (SPOM): a novel in vitro maturation system that substantially improves embryo yield and pregnancy outcomes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blastocyst; Cattle; Cell Communication; Cells, Cultured; Chori | 2010 |
Primary culture of embryonic rat olfactory receptor neurons.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cells, Cultured; Colforsin; Female; Microscopy, Fluor | 2012 |
Postnatal handling induces long-term modifications in central beta-noradrenergic signalling in rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Cerebellum; | 2002 |
Differentiation of human pulmonary type II cells in vitro by glucocorticoid plus cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Cell Differentiation; Cyclic AMP; Dexamethasone; Enzymes; Fatty Acid Sy | 2002 |
Inhibition of cyclooxygenase-2: effects on renin secretion and expression in fetal lambs.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Blood Gas Analysis; Cells, Cultured; | 2003 |
Fat accumulation in the rat during early pregnancy is modulated by enhanced insulin responsiveness.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Animals; Blood Gl | 2003 |
Platelet-derived growth factor-producing cells immortalized from rat mesencephalon with SV40 large T antigen transduced by an AAV vector.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antigens, Polyomavirus Transforming; Antineoplastic Agents; Bl | 2003 |
Characterization of an organic anion transport system in a placental cell line.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Bio | 2003 |
Chronic hypoxic decreases in soluble guanylate cyclase protein and enzyme activity are age dependent in fetal and adult ovine carotid arteries.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Carotid Arteries; Cyclic GMP; Cyclic GMP-Dependent Prot | 2006 |
Meiotic competence and acetylation pattern of UV light classified mouse antral oocytes after meiotic arrest with isobutylmethylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Acetylation; Animals; Cell Size; Cells, Cultured; Chromatin; Female; Hi | 2007 |
Developmental aspects of adipose tissue in GH receptor and prolactin receptor gene disrupted mice: site-specific effects upon proliferation, differentiation and hormone sensitivity.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adrenergic beta-Agonists; Animals; Cell Differentiation; Ce | 2006 |
Placenta-derived multipotent cells differentiate into neuronal and glial cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Animals; Animals, Newborn; Antineoplastic Agents; Astrocyte | 2008 |
Cyclic AMP as a negative regulator of hormonally induced lactogenesis in mouse mammary gland organ culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Caseins; Cholera Toxin; Cyclic AMP; Female; Hydro | 1980 |
Hormonal and nonhormonal desensitization in isolated bone cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Bone and Bones | 1980 |
Gonadocrinins: peptides in ovarian follicular fluid stimulating the secretion of pituitary gonadotropins.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Assay; Cattle; Estrus; Female; Follicle Stimulating | 1981 |
Effect of glucose on human fetal pancreatic tissue in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Female; Fetus; Glucose; Humans; In Vitro Techniques; Insulin; Insulin S | 1981 |
Facilitation of progesterone induced lordosis behavior by phosphodiesterase inhibitors in estrogen primed rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Drug Synergism; Estradiol; Estrogens; Estrus; Female; Phosphod | 1981 |
Effects of retinoic acid on differentiation of choriocarcinoma cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Cell Line; Cell Transformation, | 1982 |
Effect of 3-isobutyl-1-methylxanthine on prolactin actions on RNA synthesis, casein synthesis, lipid synthesis and ornithine decarboxylase activity in mouse mammary gland explants.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carboxy-Lyases; Caseins; Dose-Response Relationship, Drug; Fem | 1982 |
Stimulation of palatal glycosaminoglycan synthesis by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cells, Cu | 1982 |
Production of pregnancy-specific beta 1-glycoprotein by human placental cells and human fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Bromodeoxyuridine; Butyrates; Butyric Acid; Cells, Cultured; Cholera To | 1983 |
Effects of cyclic nucleotides on lipid biosynthesis in mouse mammary gland explants.
Topics: 1-Methyl-3-isobutylxanthine; Acetates; Animals; Bucladesine; Cyclic GMP; Dibutyryl Cyclic GMP; Femal | 1983 |
Prostaglandin stimulation of ornithine decarboxylase activity in mammary gland explants from mid-pregnant mice.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Alprostadil; Animals; Carboxy-Lyases; Din | 1983 |
Induction of cholinergic expression in developing spinal cord cultures.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Choline O | 1983 |
Inhibition of prostacyclin synthesis in endothelial cells by methylisobutylxanthine is not mediated through elevated cAMP level.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arachidonic Acid; Arachid | 1983 |
Regulation of thromboplastin synthesis in mouse placental cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bucladesine; C | 1983 |
Effects of 3-isobutyl-1-methylxanthine on secretory response, cAMP accumulation and DNA synthesis of islets from postnatal and adult Wistar rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; DNA; Female; Glucose; Insulin; Insulin Secretion; | 1982 |
Insulin receptors in fetal rabbit lung type II cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding, Competitive; Bucladesine; Female; Kinetics; Lung; Pre | 1984 |
In vivo adrenocorticotropin (1-24)-induced accumulation of cyclic adenosine monophosphate by ovine fetal adrenal cells is inhibited by concomitant infusion of metopirone.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cosyntropin; Cycl | 1984 |
Calcium-dependent, cyclic nucleotide-independent steroidogenesis in the bovine placenta.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Calcium; C | 1984 |
Induction of fructose 1,6-bisphosphatase and glucose 6-phosphatase by dibutyryl cyclic adenosine monophosphate in fetal mouse liver.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Bucladesine; Butyrates; Butyric Acid; Enzyme Indu | 1984 |
Induction of germ-cell alkaline phosphatase by butyrate and cyclic AMP in BeWo choriocarcinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Bucladesine; Cell Line; Cholera Toxin; Choriocarc | 1993 |
Regulation of tetrahydrobiopterin biosynthesis in cultured dopamine neurons by depolarization and cAMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biopterins; Cells, Cul | 1994 |
The expression of liver-specific genes within rat embryonic hepatocytes is a discontinuous process.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbamoyl-Phosphate Synthase (Ammonia); Cells, Cultured; Cycli | 1994 |
Oxygen modulates nitric oxide production selectively in fetal pulmonary endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Bradykinin; Calcimycin; Cells, Cul | 1994 |
The controversial role of cAMP on amnionic prostaglandin release: effect of adenylate cyclase inhibition.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amnion; Colfor | 1995 |
Activation of thyrotropin-releasing hormone gene expression in cultured fetal diencephalic neurons by differentiating agents.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine Vasopressin; Bromodeoxyuridine; Cells, Cultured; Colf | 1996 |
Differential expression of laminin chain-specific mRNA transcripts during mouse preimplantation embryo development.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Blastomeres; DNA Primers; Embryonic and Fetal D | 1996 |
The neuropeptide calcitonin gene-related peptide stimulates insulin-like growth factor I production by primary fetal rat osteoblasts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Blotting, Western; Calcitonin Gene-Related | 1996 |
Effects of sera, basic fibroblast growth factor, heparin and cyclic AMP-stimulation on proliferation of human vascular endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cattle; Cell Division; Cells, Cultured; Cholera T | 1995 |
Uptake and salvage of hypoxanthine mediates developmental arrest in preimplantation mouse embryos.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Blastocyst; Cell Count; Culture Techni | 1997 |
Tyrosine kinase inhibition decreases Muc-1 expression in mouse epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Antibodies; Base Sequence; Cell Line; Cel | 1997 |
Combined effects of fetal beta agonist stimulation and glucocorticoids on lung function of preterm lambs.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Betamethasone; Bucladesine; Ethanola | 1997 |
Cyclic AMP and cyclic GMP concentrations in, and efflux from, preimplantation cattle embryos.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blastocyst; Cattle; Cyclic AMP; Cyclic GMP; Embryo Transfer; E | 1997 |
Demonstration of a relaxin receptor and relaxin-stimulated tyrosine phosphorylation in human lower uterine segment fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Cyclic AMP; Female; Fibroblasts; Humans; Phosphorylati | 1998 |
Phosphodiesterase 3 inhibitors suppress oocyte maturation and consequent pregnancy without affecting ovulation and cyclicity in rodents.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Contraceptive Agents, Fem | 1998 |
Role of cAMP in upregulation of insulin secretion during the adaptation of islets of Langerhans to pregnancy.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Cells, Cultured; Cyclic AMP; Female; Glucose | 1998 |
Regulation of tyrosine hydroxylase gene expression during transdifferentiation of striatal neurons: changes in transcription factors binding the AP-1 site.
Topics: 1-Methyl-3-isobutylxanthine; Activating Transcription Factor 2; Animals; Base Sequence; Calcium-Calm | 1998 |
Luteinizing hormone inhibits conversion of pregnenolone to progesterone in luteal cells from rats on day 19 of pregnancy.
Topics: 1-Methyl-3-isobutylxanthine; 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Calcium Channel | 1999 |
Increase of thyrotropin response to thyrotropin-releasing hormone (TRH) and TRH release in rats during pregnancy.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Estrus; Female; Phosphodiesterase Inhibitors; Pitu | 1998 |
The role of cyclic nucleotides in the spontaneous contractility and responsiveness to nitric oxide of the rat uterus at midgestation and term.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Female; Guanylate Cyclase; | 2000 |
Whole brain spheroid cultures as a model to study the development of nitric oxide synthase-guanylate cyclase signal transduction.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Astrocytes; Atrial Natriuretic Factor; Brain; Cell Culture Tec | 2000 |
The 3T3-L1 fibroblast to adipocyte conversion is accompanied by increased expression of angiopoietin-1, a ligand for tie2.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adipocytes; Angiopoietin-1; Angiopoietin-2; Animals; Antibod | 2000 |
Expression of MSY2 in mouse oocytes and preimplantation embryos.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blastocyst; Blotting, Northern; Cytoplasm; Embryonic Developme | 2001 |
Regulation of steroid synthesis and metabolism in isolated binucleate cells of the placenta in sheep and goats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Dinoprostone; Female; Goats; Indomethacin; M | 1992 |
Responsiveness to adipogenic agents in stromal-vascular cultures derived from lean and preobese pig fetuses: an ontogeny study.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Cells, Cultured; Dexamethasone; Female; Genoty | 1992 |
Action of adenosine and characterization of adenosine receptors in human placental vasculature.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Blood Vessels; Bucladesin | 1990 |
Maternal diet and insulin secretion in islets of lactating, nonlactating, and young rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Body Weight; Bone Density; Calcium; Diet; Female; Glucose; In | 1990 |
Prostaglandins and muscarinic agonists induce cyclic AMP attenuation by two distinct mechanisms in the pregnant-rat myometrium. Interaction between cyclic AMP and Ca2+ signals.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Animals; Calcium; Carbachol; Cyclic AMP; Dinop | 1990 |
Biosynthesis of P450 products of arachidonic acid in humans: increased formation in cardiovascular disease.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,1 | 1991 |
Mammalian cell lines engineered to identify inhibitors of specific signal transduction pathways.
Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Animals; Base Sequence; Cell Line; Clone Cells; C | 1991 |
Phospholipid turnover and ultrastructural correlates during spontaneous germinal vesicle breakdown of the bovine oocyte: effects of a cyclic AMP phosphodiesterase inhibitor.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cattle; Cell Differentiat | 1991 |
Role of cyclic adenosine 3',5'-monophosphate in mediating the effect of prostaglandin E2 on decidualization in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Animals; Cell Nucleus; Cells, Cultured; Cholera T | 1991 |
Primary structure of frog pituitary adenylate cyclase-activating polypeptide (PACAP) and effects of ovine PACAP on frog pituitary.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Brain Chemistry; Cyclic AMP; Female; Mole | 1991 |
cAMP-dependent regulation of P450-catalyzed dealkylation in rat conceptal tissues.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Culture Techniques; Cyclic AMP; Cytochrome P-450 | 1991 |
Effects of perinatal administration of isobutyl methylxanthine (IBMX) on [3H]-DA binding in the forebrain of the rat.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding, Competitive; Body Weight; Cyclic AMP; Diencephalon; D | 1986 |
Lack of ovarian responsiveness to gonadotropic hormones in infantile rats sterilized with busulfan.
Topics: 1-Methyl-3-isobutylxanthine; Androstenedione; Animals; Busulfan; Cyclic AMP; Estradiol; Female; Foll | 1986 |
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Fe | 1986 |
Cyclic AMP inhibits the release of prostaglandins and arachidonic acid from cultures of mouse embryo palate mesenchyme cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Bucladesine; Cells, Cultu | 1986 |
Cyclic AMP inhibits the synthesis and release of prolactin from human decidual cells.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dec | 1987 |
Cyclic adenosine-3',5'-monophosphate stimulates the acute release of placental lactogen from human trophoblast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Bucladesine; Cells, Cultured; Cholera Toxi | 1987 |
Effect of dietary lipids on inotropic responses of isolated rat left atrium: attenuation of maximal responses by an unsaturated fat diet.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Buclad | 1987 |
Control of bovine placental progesterone synthesis: roles of cholesterol availability and calcium-activated systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Calcium; Cattle; Cholesterol; Drug Interactions; F | 1988 |
Effects of caffeine and 3-isobutyl 1-methyl xanthine on caprine milk secretion.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Fats; Female; Goats; Infusions, Intravenous; Injecti | 1988 |
Roles of insulin and growth hormone in the adaptations of fatty acid synthesis in white adipose tissue during the lactation cycle in sheep.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Culture Techniques; Dactinomycin; Dexamethason | 1988 |
Influence of cyclic nucleotides on the processing of the carbohydrate part of the alpha-subunit of human choriogonadotropin by first trimester human placenta tissue.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; alpha-Mannosidase; Carbohydrate | 1989 |
Enzyme activation of human prolactin: a potential basis for a bioassay.
Topics: 1-Methyl-3-isobutylxanthine; 4-Nitrophenylphosphatase; Adenosine Triphosphatases; Amnion; Cells, Cul | 1989 |
Regulation of side-chain cleavage enzyme and 3 beta-hydroxysteroid dehydrogenase by Ca2+ second messenger and protein kinase C systems in the placenta of the cow.
Topics: 1-Methyl-3-isobutylxanthine; 3-Hydroxysteroid Dehydrogenases; Animals; Calcimycin; Calcium; Cattle; | 1989 |
Mechanism of the luteolytic action of prostaglandin F-2 alpha in the rat.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Calcium; Corpu | 1989 |
Evidence for a role for adenosine 3',5'-monophosphate in progesterone secretion by human chorion.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Cholera Toxin; Chorion; Colforsin; Cyclic AMP; Diterpenes; | 1985 |
Influence of cyclic nucleotides on receptor binding, immunological activity, and microheterogeneity of human choriogonadotropin synthesized in placental tissue culture.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chorionic Gonadotropin | 1985 |