1-methyl-3-isobutylxanthine has been researched along with Porphyrias in 2 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Varone, CL | 1 |
| Canepa, ET | 1 |
| Llambias, EB | 1 |
| Grinstein, M | 1 |
| Marks, GS | 1 |
| Stephens, JK | 1 |
| Fischer, PW | 1 |
| Morgan, RO | 1 |
1 review available for 1-methyl-3-isobutylxanthine and Porphyrias
| Article | Year |
|---|---|
Hormonal effects on the regulation of hepatic heme biosynthesis.
Topics: 1-Methyl-3-isobutylxanthine; 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Androstanes; Ani | 1979 |
1 other study available for 1-methyl-3-isobutylxanthine and Porphyrias
| Article | Year |
|---|---|
Glucose inhibits phenobarbital-induced delta-aminolevulinate synthase expression in normal but not in diabetic rat hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 5-Aminolevulinate Synthetase; Aden | 1996 |