1-methyl-3-isobutylxanthine has been researched along with Pheochromocytoma, Extra-Adrenal in 9 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Atrial natriuretic factors (ANFs) were tested for their effects on cyclic GMP production in two neurally derived cell lines, the C6-2B rat glioma cells and the PC12 rat pheochromocytoma cells." | 7.67 | Atrial natriuretic factors stimulate accumulation and efflux of cyclic GMP in C6-2B rat glioma and PC12 rat pheochromocytoma cell cultures. ( Fiscus, RR; Murad, F; Robles, BT; Waldman, SA, 1987) |
| "Atrial natriuretic factors (ANFs) were tested for their effects on cyclic GMP production in two neurally derived cell lines, the C6-2B rat glioma cells and the PC12 rat pheochromocytoma cells." | 3.67 | Atrial natriuretic factors stimulate accumulation and efflux of cyclic GMP in C6-2B rat glioma and PC12 rat pheochromocytoma cell cultures. ( Fiscus, RR; Murad, F; Robles, BT; Waldman, SA, 1987) |
| "Nerve growth factor (NGF) rapidly increases the cyclic GMP (cGMP) level about 2-3-fold and enhances the cGMP phosphodiesterase (PDE) activity about 2-fold in rat pheochromocytoma PC12 cells." | 3.67 | Nerve growth factor increases the cyclic GMP level and activates the cyclic GMP phosphodiesterase in PC12 cells. ( Laasberg, T; Neuman, T; Paves, H; Pihlak, A; Saarma, M, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brady, MJ | 2 |
| Nairn, AC | 2 |
| Wagner, JA | 1 |
| Palfrey, HC | 2 |
| Kalman, D | 1 |
| Wong, B | 1 |
| Horvai, AE | 1 |
| Cline, MJ | 1 |
| O'Lague, PH | 1 |
| Delpire, E | 1 |
| Cornet, M | 1 |
| Gilles, R | 1 |
| Tank, AW | 1 |
| Ham, L | 1 |
| Curella, P | 1 |
| Fiscus, RR | 1 |
| Robles, BT | 1 |
| Waldman, SA | 1 |
| Murad, F | 1 |
| Nichols, RA | 1 |
| Hoshi, T | 1 |
| Garber, SS | 1 |
| Aldrich, RW | 1 |
| Laasberg, T | 1 |
| Pihlak, A | 1 |
| Neuman, T | 1 |
| Paves, H | 1 |
| Saarma, M | 1 |
| Shen, RS | 1 |
| Zhang, YX | 1 |
| Perez-Polo, JR | 1 |
9 other studies available for 1-methyl-3-isobutylxanthine and Pheochromocytoma, Extra-Adrenal
| Article | Year |
|---|---|
Nerve growth factor-induced down-regulation of calmodulin-dependent protein kinase III in PC12 cells involves cyclic AMP-dependent protein kinase.
Topics: 1-Methyl-3-isobutylxanthine; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Elongati | 1990 |
Nerve growth factor acts through cAMP-dependent protein kinase to increase the number of sodium channels in PC12 cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Gland Neoplasms; Animals; Bucladesine; Cell Differentiation; Ce | 1990 |
Volume regulation in rat pheochromocytoma cultured cells submitted to hypoosmotic conditions.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Gland Neoplasms; Amiloride; Animals; Colforsin; Hypotonic Solut | 1991 |
Induction of tyrosine hydroxylase by cyclic AMP and glucocorticoids in a rat pheochromocytoma cell line: effect of the inducing agents alone or in combination on the enzyme levels and rate of synthesis of tyrosine hydroxylase.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Gland Neoplasms; Animal | 1986 |
Atrial natriuretic factors stimulate accumulation and efflux of cyclic GMP in C6-2B rat glioma and PC12 rat pheochromocytoma cell cultures.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Gland Neoplasms; Animals; Atrial Natriuretic Factor; Cell Line; | 1987 |
Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adrenal Gland Neoplasms; Animals; Calcium | 1987 |
Effect of forskolin on voltage-gated K+ channels is independent of adenylate cyclase activation.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenal Gland Neoplasms; Colforsin; Cyclic AMP; Elec | 1988 |
Nerve growth factor increases the cyclic GMP level and activates the cyclic GMP phosphodiesterase in PC12 cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterase | 1988 |
Regulation of GTP cyclohydrolase I and dihydropteridine reductase in rat pheochromocytoma PC 12 cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Gland Neoplasms; Animal | 1989 |