1-methyl-3-isobutylxanthine has been researched along with Peripheral Arterial Disease in 1 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Peripheral Arterial Disease: Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to evaluate hemorheological changes in patients with cerebrovascular disease (CVD) and peripheral arterial disease (PAD) after 4 weeks of pentoxifylline therapy as well as to study red blood cell microrheological variables after the cell incubation with pentoxifylline and some phosphodiesterase (PDE) activity inhibitors." | 5.15 | Macro- and microrheological parameters of blood in patients with cerebral and peripheral atherosclerosis: the molecular change mechanisms after pentoxifylline treatment. ( Bulaeva, SV; Miloradov, MJ; Muravyov, AV; Tikhomirova, IA; Uzikova, EV; Zamishlayev, AV, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muravyov, AV | 1 |
| Bulaeva, SV | 1 |
| Tikhomirova, IA | 1 |
| Zamishlayev, AV | 1 |
| Uzikova, EV | 1 |
| Miloradov, MJ | 1 |
1 trial available for 1-methyl-3-isobutylxanthine and Peripheral Arterial Disease
| Article | Year |
|---|---|
Macro- and microrheological parameters of blood in patients with cerebral and peripheral atherosclerosis: the molecular change mechanisms after pentoxifylline treatment.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Anemia; Blood Transfusion; Erythrocytes; Erythropoietin; F | 2011 |