1-methyl-3-isobutylxanthine has been researched along with Osteoarthritis in 1 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karsdal, MA | 1 |
| Sumer, EU | 1 |
| Wulf, H | 1 |
| Madsen, SH | 1 |
| Christiansen, C | 1 |
| Fosang, AJ | 1 |
| Sondergaard, BC | 1 |
1 other study available for 1-methyl-3-isobutylxanthine and Osteoarthritis
| Article | Year |
|---|---|
Induction of increased cAMP levels in articular chondrocytes blocks matrix metalloproteinase-mediated cartilage degradation, but not aggrecanase-mediated cartilage degradation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcitonin; Cartilage, Articular; Cattle; Cells, Cultured; Col | 2007 |