1-methyl-3-isobutylxanthine has been researched along with Obesity in 16 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nobiletin is a citrus flavonoid which possesses the flavone structure with six methoxy groups." | 1.38 | Nobiletin suppresses adipocyte differentiation of 3T3-L1 cells by an insulin and IBMX mixture induction. ( Kadota, A; Kanda, K; Liu, MC; Nishi, K; Nishimoto, S; Sugahara, T, 2012) |
| "Upper body obesity is characterized by an expansion of the visceral adipose tissue and is associated with an increased susceptibility for type 2 diabetes and cardiovascular disease." | 1.32 | Comparison of proliferation and differentiation capacity of human adipocyte precursor cells from the omental and subcutaneous adipose tissue depot of obese subjects. ( Hauner, H; Röhrig, K; Van Harmelen, V, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SO | 1 |
| Sakchaisri, K | 1 |
| Asami, Y | 1 |
| Ryoo, IJ | 1 |
| Choo, SJ | 1 |
| Yoo, ID | 1 |
| Soung, NK | 1 |
| Kim, YS | 1 |
| Jang, JH | 1 |
| Kim, BY | 1 |
| Ahn, JS | 1 |
| Ribeiro-Parenti, L | 1 |
| Jarry, AC | 1 |
| Cavin, JB | 1 |
| Willemetz, A | 1 |
| Le Beyec, J | 1 |
| Sannier, A | 1 |
| Benadda, S | 1 |
| Pelletier, AL | 1 |
| Hourseau, M | 1 |
| Léger, T | 1 |
| Morlet, B | 1 |
| Couvelard, A | 1 |
| Anini, Y | 1 |
| Msika, S | 1 |
| Marmuse, JP | 1 |
| Ledoux, S | 1 |
| Le Gall, M | 1 |
| Bado, A | 1 |
| Balbo, SL | 1 |
| Ribeiro, RA | 1 |
| Mendes, MC | 1 |
| Lubaczeuski, C | 1 |
| Maller, AC | 1 |
| Carneiro, EM | 1 |
| Bonfleur, ML | 1 |
| Kanda, K | 1 |
| Nishi, K | 1 |
| Kadota, A | 1 |
| Nishimoto, S | 1 |
| Liu, MC | 1 |
| Sugahara, T | 1 |
| Jia, B | 1 |
| Madsen, L | 1 |
| Petersen, RK | 1 |
| Techer, N | 1 |
| Kopperud, R | 1 |
| Ma, T | 1 |
| Døskeland, SO | 1 |
| Ailhaud, G | 1 |
| Wang, J | 1 |
| Amri, EZ | 1 |
| Kristiansen, K | 1 |
| Van Harmelen, V | 1 |
| Röhrig, K | 1 |
| Hauner, H | 1 |
| Kim, JY | 1 |
| Wu, Y | 1 |
| Smas, CM | 1 |
| Murakami, T | 1 |
| Iida, M | 1 |
| Shima, K | 1 |
| Black, MA | 1 |
| Bégin-Heick, N | 1 |
| Poitout, V | 1 |
| Rouault, C | 1 |
| Guerre-Millo, M | 1 |
| Briaud, I | 1 |
| Reach, G | 1 |
| Frühbeck, G | 1 |
| Gómez-Ambrosi, J | 1 |
| Salvador, J | 1 |
| Netherton, SJ | 1 |
| Jimmo, SL | 1 |
| Palmer, D | 1 |
| Tilley, DG | 1 |
| Dunkerley, HA | 1 |
| Raymond, DR | 1 |
| Russell, JC | 1 |
| Absher, PM | 1 |
| Sage, EH | 1 |
| Vernon, RB | 1 |
| Maurice, DH | 1 |
| Hausman, GJ | 1 |
| Khan, A | 1 |
| Ostenson, CG | 1 |
| Berggren, PO | 1 |
| Efendic, S | 1 |
| Cawthorn, EG | 1 |
| Chan, CB | 1 |
| Crandall, DL | 1 |
| Vu, V | 1 |
| Lizzo, FH | 1 |
| Davis, BA | 1 |
| Cervoni, P | 1 |
16 other studies available for 1-methyl-3-isobutylxanthine and Obesity
| Article | Year |
|---|---|
Illudins C2 and C3 stimulate lipolysis in 3T3-L1 adipocytes and suppress adipogenesis in 3T3-L1 preadipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhance | 2014 |
Bariatric surgery induces a new gastric mucosa phenotype with increased functional glucagon-like peptide-1 expressing cells.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Amino Acid Sequence; Animals; Bariatric Surgery; Diet, High-Fat; | 2021 |
Vagotomy diminishes obesity in cafeteria rats by decreasing cholinergic potentiation of insulin release.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Body Weight; Carbachol; Colforsin; Cyclic AMP; | 2016 |
Nobiletin suppresses adipocyte differentiation of 3T3-L1 cells by an insulin and IBMX mixture induction.
Topics: 1-Methyl-3-isobutylxanthine; 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Antioxidants; Cell Dif | 2012 |
Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adipose Tissue; Animals; Cell Differentiation; Cell Line; C | 2012 |
Comparison of proliferation and differentiation capacity of human adipocyte precursor cells from the omental and subcutaneous adipose tissue depot of obese subjects.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adipose Tissue; Adolescent; Adult; Case-Control Studies; Ce | 2004 |
Characterization of ScAP-23, a new cell line from murine subcutaneous adipose tissue, identifies genes for the molecular definition of preadipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Biomarkers; Cell Diffe | 2007 |
Dexamethasone regulates obese expression in isolated rat adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adipocytes; Adipose Tissue; Adipose Tissue, Brown; Animals; | 1995 |
Growth and maturation of primary-cultured adipocytes from lean and ob/ob mice.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Animals; Cattle; Cell Cycle; Cell Differentiation; Cell Div | 1995 |
Inhibition of insulin secretion by leptin in normal rodent islets of Langerhans.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Insulin; Insulin Secretion; Islets of Langer | 1998 |
Leptin-induced lipolysis opposes the tonic inhibition of endogenous adenosine in white adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylate Cyclase Toxin; Adipocytes; Adipose Tissue; Animals | 2001 |
Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR:LA-cp rat aortic vascular smooth muscle cells: implications for diabetes-associated cardiovascular disease.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imi | 2002 |
Responsiveness to adipogenic agents in stromal-vascular cultures derived from lean and preobese pig fetuses: an ontogeny study.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Cells, Cultured; Dexamethasone; Female; Genoty | 1992 |
Glucocorticoid increases glucose cycling and inhibits insulin release in pancreatic islets of ob/ob mice.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Dexamethasone; Glucose; Hyperglycemia; Insulin; | 1992 |
Effect of pertussis toxin on islet insulin secretion in obese (fa/fa) Zucker rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Epinephrine; Female; Galanin; Glucose; GTP-Binding | 1991 |
Antilipolytic activity of viprostol, a transdermally active antihypertensive PGE2 analog.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Antihypertensive Agents; Dinoprostone; Epineph | 1987 |