1-methyl-3-isobutylxanthine has been researched along with Nerve Degeneration in 4 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vallazza-Deschamps, G | 1 |
| Cia, D | 1 |
| Gong, J | 1 |
| Jellali, A | 1 |
| Duboc, A | 1 |
| Forster, V | 1 |
| Sahel, JA | 1 |
| Tessier, LH | 1 |
| Picaud, S | 1 |
| Hanson, MG | 1 |
| Shen, S | 1 |
| Wiemelt, AP | 1 |
| McMorris, FA | 1 |
| Barres, BA | 1 |
| Patrizio, M | 1 |
| Colucci, M | 1 |
| Levi, G | 1 |
| Williams, DS | 1 |
| Colley, NJ | 1 |
| Farber, DB | 1 |
4 other studies available for 1-methyl-3-isobutylxanthine and Nerve Degeneration
| Article | Year |
|---|---|
Excessive activation of cyclic nucleotide-gated channels contributes to neuronal degeneration of photoreceptors.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Blotting, Western; Cadmium Chloride; Calcium | 2005 |
Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bone Morphogenetic Proteins; Brain-Derived Neurotrophic Factor | 1998 |
Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Antibodies, Monocl | 2001 |
Photoreceptor degeneration in a pure-cone retina. Effects of cyclic nucleotides, and inhibitors of phosphodiesterase and protein synthesis.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Dibutyryl Cyclic GMP; Lizards; Nerve Degeneration | 1987 |