1-methyl-3-isobutylxanthine has been researched along with Neoplasm Metastasis in 6 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fusion of Cloudman S91 melanoma cells with macrophages results in hybrids with increased metastatic potential." | 1.30 | Acquired melanocyte stimulating hormone-inducible chemotaxis following macrophage fusion with Cloudman S91 melanoma cells. ( Pawelek, J; Rachkovsky, M, 1999) |
| "Clin." | 1.30 | Upregulation of mRNA for the melanocortin-1 receptor but not for melanogenic proteins in macrophage x melanoma fusion hybrids exhibiting increased melanogenic and metastatic potential. ( Bhattacharya, M; Chakraborty, AK; Funasaka, Y; Ichihashi, M; Pawelek, J; Sodi, S, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janik, P | 1 |
| Assaf, A | 1 |
| Bertram, JS | 1 |
| Daneker, GW | 1 |
| Lund, SA | 1 |
| Caughman, SW | 1 |
| Staley, CA | 1 |
| Wood, WC | 1 |
| Rachkovsky, M | 1 |
| Pawelek, J | 2 |
| Chakraborty, AK | 2 |
| Funasaka, Y | 1 |
| Ichihashi, M | 1 |
| Sodi, S | 1 |
| Bhattacharya, M | 1 |
| Pawelek, JM | 1 |
| Rachkovsky, ML | 1 |
| Orlow, SJ | 1 |
| Bolognia, JL | 1 |
| Sodi, SA | 1 |
| Lester, BR | 1 |
| McCarthy, JB | 1 |
| Sun, ZQ | 1 |
| Smith, RS | 1 |
| Furcht, LT | 1 |
| Spiegel, AM | 1 |
6 other studies available for 1-methyl-3-isobutylxanthine and Neoplasm Metastasis
| Article | Year |
|---|---|
Inhibition of growth of primary and metastatic Lewis lung carcinoma cells by the phosphodiesterase inhibitor isobutylmethylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Division; Female; Lung Neoplasms; Male; Mice; Neoplasm Me | 1980 |
Anti-metastatic prostacyclins inhibit the adhesion of colon carcinoma to endothelial cells by blocking E-selectin expression.
Topics: 1-Methyl-3-isobutylxanthine; Antineoplastic Agents; Bucladesine; Carcinoma; Cell Adhesion; Cells, Cu | 1996 |
Acquired melanocyte stimulating hormone-inducible chemotaxis following macrophage fusion with Cloudman S91 melanoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Fusion; Chemotactic Factors; Chemotaxis; Culture Media, C | 1999 |
Upregulation of mRNA for the melanocortin-1 receptor but not for melanogenic proteins in macrophage x melanoma fusion hybrids exhibiting increased melanogenic and metastatic potential.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Fusion; Humans; Hybridomas; Macrophages, Peritoneal; Mela | 1999 |
Altered N-glycosylation in macrophage x melanoma fusion hybrids.
Topics: 1-Methyl-3-isobutylxanthine; alpha-MSH; Animals; Antigens, CD; Glucosamine; Glycosylation; Humans; H | 1999 |
G-protein involvement in matrix-mediated motility and invasion of high and low experimental metastatic B16 melanoma clones.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylate Cyclase Toxin; Animals; Cell Line; Cell Membrane; Ce | 1989 |