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1-methyl-3-isobutylxanthine and Neoplasm Metastasis

1-methyl-3-isobutylxanthine has been researched along with Neoplasm Metastasis in 6 studies

1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"Fusion of Cloudman S91 melanoma cells with macrophages results in hybrids with increased metastatic potential."1.30Acquired melanocyte stimulating hormone-inducible chemotaxis following macrophage fusion with Cloudman S91 melanoma cells. ( Pawelek, J; Rachkovsky, M, 1999)
"Clin."1.30Upregulation of mRNA for the melanocortin-1 receptor but not for melanogenic proteins in macrophage x melanoma fusion hybrids exhibiting increased melanogenic and metastatic potential. ( Bhattacharya, M; Chakraborty, AK; Funasaka, Y; Ichihashi, M; Pawelek, J; Sodi, S, 1999)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Janik, P1
Assaf, A1
Bertram, JS1
Daneker, GW1
Lund, SA1
Caughman, SW1
Staley, CA1
Wood, WC1
Rachkovsky, M1
Pawelek, J2
Chakraborty, AK2
Funasaka, Y1
Ichihashi, M1
Sodi, S1
Bhattacharya, M1
Pawelek, JM1
Rachkovsky, ML1
Orlow, SJ1
Bolognia, JL1
Sodi, SA1
Lester, BR1
McCarthy, JB1
Sun, ZQ1
Smith, RS1
Furcht, LT1
Spiegel, AM1

Other Studies

6 other studies available for 1-methyl-3-isobutylxanthine and Neoplasm Metastasis

ArticleYear
Inhibition of growth of primary and metastatic Lewis lung carcinoma cells by the phosphodiesterase inhibitor isobutylmethylxanthine.
    Cancer research, 1980, Volume: 40, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Division; Female; Lung Neoplasms; Male; Mice; Neoplasm Me

1980
Anti-metastatic prostacyclins inhibit the adhesion of colon carcinoma to endothelial cells by blocking E-selectin expression.
    Clinical & experimental metastasis, 1996, Volume: 14, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Antineoplastic Agents; Bucladesine; Carcinoma; Cell Adhesion; Cells, Cu

1996
Acquired melanocyte stimulating hormone-inducible chemotaxis following macrophage fusion with Cloudman S91 melanoma cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1999, Volume: 10, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Fusion; Chemotactic Factors; Chemotaxis; Culture Media, C

1999
Upregulation of mRNA for the melanocortin-1 receptor but not for melanogenic proteins in macrophage x melanoma fusion hybrids exhibiting increased melanogenic and metastatic potential.
    Pigment cell research, 1999, Volume: 12, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Fusion; Humans; Hybridomas; Macrophages, Peritoneal; Mela

1999
Altered N-glycosylation in macrophage x melanoma fusion hybrids.
    Cellular and molecular biology (Noisy-le-Grand, France), 1999, Volume: 45, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; alpha-MSH; Animals; Antigens, CD; Glucosamine; Glycosylation; Humans; H

1999
G-protein involvement in matrix-mediated motility and invasion of high and low experimental metastatic B16 melanoma clones.
    Cancer research, 1989, Nov-01, Volume: 49, Issue:21

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylate Cyclase Toxin; Animals; Cell Line; Cell Membrane; Ce

1989