Compounds > 1-methyl-3-isobutylxanthine
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1-methyl-3-isobutylxanthine and Leukemia, T-Cell

1-methyl-3-isobutylxanthine has been researched along with Leukemia, T-Cell in 3 studies

1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.

Leukemia, T-Cell: A malignant disease of the T-LYMPHOCYTES in the bone marrow, thymus, and/or blood.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rothem, L1
Stark, M2
Assaraf, YG2
Jiang, X1
Paskind, M1
Weltzien, R1
Epstein, PM1

Other Studies

3 other studies available for 1-methyl-3-isobutylxanthine and Leukemia, T-Cell

ArticleYear
Impaired CREB-1 phosphorylation in antifolate-resistant cell lines with down-regulation of the reduced folate carrier gene.
    Molecular pharmacology, 2004, Volume: 66, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Carrier Proteins; Cell Line, Tumor; Colforsin; Cyclic AMP

2004
Loss of Sp1 function via inhibitory phosphorylation in antifolate-resistant human leukemia cells with down-regulation of the reduced folate carrier.
    Blood, 2006, Jan-15, Volume: 107, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Binding Sites; Cyclic AMP; Cyclic AMP-Dependent P

2006
Expression and regulation of mRNA for distinct isoforms of cAMP-specific PDE-4 in mitogen-stimulated and leukemic human lymphocytes.
    Cell biochemistry and biophysics, 1998, Volume: 28, Issue:2-3

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; B-Lymphocytes; Bucladesine; Cyclic

1998