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1-methyl-3-isobutylxanthine and Leukemia, Myeloid, Acute

1-methyl-3-isobutylxanthine has been researched along with Leukemia, Myeloid, Acute in 5 studies

1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gespach, C1
Saal, F1
Cost, H1
Abita, JP1
Sawutz, DG1
Kalinyak, K1
Whitsett, JA1
Johnson, CL1
Fontana, J1
Munoz, M1
Durham, J1
Lanotte, M1
Hermouet, S1
Gombaud-Saintonge, G1
Dobo, I1
Slungaard, A1
Confer, DL1
Schubach, WH1

Other Studies

5 other studies available for 1-methyl-3-isobutylxanthine and Leukemia, Myeloid, Acute

ArticleYear
Identification and characterization of surface receptors for histamine in the human promyelocytic leukemia cell line HL-60. Comparison with human peripheral neutrophils.
    Molecular pharmacology, 1982, Volume: 22, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Cyclic AMP; Humans; Leukemia, Experimental; Leukemi

1982
Histamine H2 receptor desensitization in HL-60 human promyelocytic leukemia cells.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Cell Differentiation; Cell Line; Cimetidine; Cyclic AMP; Dimaprit; Dino

1984
Potentiation between intracellular cyclic-AMP-elevating agents and inducers of leukemic cell differentiation.
    Leukemia research, 1985, Volume: 9, Issue:9

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Cell Differentiation; Cell Line

1985
On growth regulation of the rat promyelocytic leukemia (BNML): growth inhibition and eradication of clonogenic cells by cholera toxin.
    Leukemia research, 1986, Volume: 10, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cell Division; Cell Line; Cholera Toxin; Cl

1986
Rapid transcriptional down-regulation of c-myc expression during cyclic adenosine monophosphate-promoted differentiation of leukemic cells.
    The Journal of clinical investigation, 1987, Volume: 79, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Cell Differentiation; Cell Line; Cholera Toxin; Cyclic AMP

1987