1-methyl-3-isobutylxanthine has been researched along with Leukemia, Myeloid, Acute in 5 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gespach, C | 1 |
| Saal, F | 1 |
| Cost, H | 1 |
| Abita, JP | 1 |
| Sawutz, DG | 1 |
| Kalinyak, K | 1 |
| Whitsett, JA | 1 |
| Johnson, CL | 1 |
| Fontana, J | 1 |
| Munoz, M | 1 |
| Durham, J | 1 |
| Lanotte, M | 1 |
| Hermouet, S | 1 |
| Gombaud-Saintonge, G | 1 |
| Dobo, I | 1 |
| Slungaard, A | 1 |
| Confer, DL | 1 |
| Schubach, WH | 1 |
5 other studies available for 1-methyl-3-isobutylxanthine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Identification and characterization of surface receptors for histamine in the human promyelocytic leukemia cell line HL-60. Comparison with human peripheral neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Cyclic AMP; Humans; Leukemia, Experimental; Leukemi | 1982 |
Histamine H2 receptor desensitization in HL-60 human promyelocytic leukemia cells.
Topics: 1-Methyl-3-isobutylxanthine; Cell Differentiation; Cell Line; Cimetidine; Cyclic AMP; Dimaprit; Dino | 1984 |
Potentiation between intracellular cyclic-AMP-elevating agents and inducers of leukemic cell differentiation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Cell Differentiation; Cell Line | 1985 |
On growth regulation of the rat promyelocytic leukemia (BNML): growth inhibition and eradication of clonogenic cells by cholera toxin.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cell Division; Cell Line; Cholera Toxin; Cl | 1986 |
Rapid transcriptional down-regulation of c-myc expression during cyclic adenosine monophosphate-promoted differentiation of leukemic cells.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Cell Differentiation; Cell Line; Cholera Toxin; Cyclic AMP | 1987 |