1-methyl-3-isobutylxanthine has been researched along with Leucocythaemia in 5 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bufalin, an active principle of Chinese medicine, chan'su, induced typical apoptosis in human leukemia U937 cells." | 7.69 | The cooperative interaction of two different signaling pathways in response to bufalin induces apoptosis in human leukemia U937 cells. ( Kuroiwa, Y; Masuda, Y; Nakajo, S; Nakaya, K; Watabe, M; Yoshida, T, 1996) |
| "Bufalin, an active principle of Chinese medicine, chan'su, induced typical apoptosis in human leukemia U937 cells." | 3.69 | The cooperative interaction of two different signaling pathways in response to bufalin induces apoptosis in human leukemia U937 cells. ( Kuroiwa, Y; Masuda, Y; Nakajo, S; Nakaya, K; Watabe, M; Yoshida, T, 1996) |
| "This study demonstrates synergistic effects on Tac expression by interleukin 1 (IL-1) or tumor necrosis factor alpha (TNF alpha) in combination with the adenylate cyclase stimulator, forskolin (FK), as well as by IL-1 with TNF alpha in the human NK-like leukemic cell line YT." | 1.28 | Synergistic induction of interleukin 2 receptor (TAC) expression on YT cells by interleukin 1 or tumor necrosis factor alpha in combination with cAMP inducing agents. ( Altman, A; Scholz, W, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Epstein, PM | 1 |
| Hachisu, R | 1 |
| Watabe, M | 1 |
| Masuda, Y | 1 |
| Nakajo, S | 1 |
| Yoshida, T | 1 |
| Kuroiwa, Y | 1 |
| Nakaya, K | 1 |
| Hohmann, HP | 1 |
| Kolbeck, R | 1 |
| Remy, R | 1 |
| van Loon, AP | 1 |
| Wacholtz, MC | 1 |
| Minakuchi, R | 1 |
| Lipsky, PE | 1 |
| Scholz, W | 1 |
| Altman, A | 1 |
1 review available for 1-methyl-3-isobutylxanthine and Leucocythaemia
| Article | Year |
|---|---|
Cyclic nucleotide phosphodiesterase in normal and leukemic human lymphocytes and lymphoblasts.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterase | 1984 |
4 other studies available for 1-methyl-3-isobutylxanthine and Leucocythaemia
| Article | Year |
|---|---|
The cooperative interaction of two different signaling pathways in response to bufalin induces apoptosis in human leukemia U937 cells.
Topics: 1-Methyl-3-isobutylxanthine; Antineoplastic Agents; Apoptosis; Bufanolides; Calcium-Calmodulin-Depen | 1996 |
Cyclic AMP-independent activation of transcription factor NF-kappa B in HL60 cells by tumor necrosis factors alpha and beta.
Topics: 1-Methyl-3-isobutylxanthine; Colforsin; Cyclic AMP; Gene Expression Regulation; Humans; Kinetics; Le | 1991 |
Characterization of the 3',5'-cyclic adenosine monophosphate-mediated regulation of IL2 production by T cells and Jurkat cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Cell Line; Cholera Toxin; C | 1991 |
Synergistic induction of interleukin 2 receptor (TAC) expression on YT cells by interleukin 1 or tumor necrosis factor alpha in combination with cAMP inducing agents.
Topics: 1-Methyl-3-isobutylxanthine; Colforsin; Cyclic AMP; Drug Synergism; Fluorescence; Humans; Interleuki | 1989 |