1-methyl-3-isobutylxanthine has been researched along with Kidney Failure, Chronic in 2 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dousa, TP | 1 |
| Shah, SV | 1 |
| Abboud, HE | 1 |
| Bertuccio, C | 1 |
| Ibarra, FR | 1 |
| Pignataro, O | 1 |
| Toledo, J | 1 |
| Paz, L | 1 |
| Arrizurieta, E | 1 |
| Martin, RS | 1 |
1 review available for 1-methyl-3-isobutylxanthine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Potential role of cyclic nucleotides in glomerular pathophysiology.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cholera Toxin; Cyclic AMP; Cyclic GMP; Disease Models, Animal; | 1980 |
1 other study available for 1-methyl-3-isobutylxanthine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Regulation of cell cyclic AMP in medullary thick ascending limb of Henle in a rat model of chronic renal failure.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Animals; Calcitonin; Cell Separation; Clonid | 1998 |