1-methyl-3-isobutylxanthine has been researched along with Island Cell Tumor in 8 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A series of 3H-leucine pulse-labeling experiments was carried out with dispersed cells freshly isolated from transplanted rat insulinomas." | 3.67 | Contrasting patterns of insulin biosynthesis, compartmental storage, and secretion. Rat tumor versus islet cells. ( Chick, WL; Gishizky, ML; Gold, G; Grodsky, GM, 1984) |
| "Glucose, forskolin, IBMX and carbachol all stimulated insulin release from freshly obtained human insulinoma cells." | 3.67 | Glucose stimulates insulin release without altering cyclic AMP production or inositolphospholipid turnover in freshly obtained human insulinoma cells. ( Chiba, T; Fujita, T; Inui, T; Kadowaki, S; Saito, Y; Yamaguchi, A; Yamatani, T, 1987) |
| "Using a rat islet cell tumor in culture, Rin-m, we studied the effects of the neuropeptide, galanin, on somatostatin release." | 1.28 | Galanin inhibits somatostatin release by the rat islet cell tumor in culture, Rin-m. ( Amiranoff, B; Laburthe, M; Lorinet, AM, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Masiello, P | 1 |
| Wollheim, CB | 1 |
| Janjic, D | 1 |
| Gjinovci, A | 1 |
| Blondel, B | 1 |
| Praz, GA | 1 |
| Renold, AE | 1 |
| Gold, G | 1 |
| Gishizky, ML | 1 |
| Chick, WL | 1 |
| Grodsky, GM | 1 |
| D'Ambra, R | 1 |
| Surana, M | 1 |
| Efrat, S | 1 |
| Starr, RG | 1 |
| Fleischer, N | 2 |
| Amiranoff, B | 1 |
| Lorinet, AM | 1 |
| Laburthe, M | 1 |
| Pasmantier, R | 1 |
| Danoff, A | 1 |
| Schubart, UK | 1 |
| Chiba, T | 1 |
| Yamatani, T | 1 |
| Kadowaki, S | 1 |
| Yamaguchi, A | 1 |
| Inui, T | 1 |
| Saito, Y | 1 |
| Fujita, T | 1 |
| Harty, RF | 1 |
| Jain, DK | 1 |
| McGuigan, JE | 1 |
| Thivolet, CH | 1 |
| Demidem, A | 1 |
| Haftek, M | 1 |
| Durand, A | 1 |
| Bertrand, J | 1 |
8 other studies available for 1-methyl-3-isobutylxanthine and Island Cell Tumor
| Article | Year |
|---|---|
Stimulation of insulin release by glucose in a transplantable rat islet cell tumor.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Blood Glucose; Cells, Cultured; Glucose; | 1982 |
Contrasting patterns of insulin biosynthesis, compartmental storage, and secretion. Rat tumor versus islet cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Female; Glucose; In Vitro Techniques; Ins | 1984 |
Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Carbachol; Colforsin; Cyclic AMP; Drug Sy | 1990 |
Galanin inhibits somatostatin release by the rat islet cell tumor in culture, Rin-m.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Aprotinin; Arginine; Depression, Chemical | 1990 |
P19, a hormonally regulated phosphoprotein of peptide hormone-producing cells: secretagogue-induced phosphorylation in AtT-20 mouse pituitary tumor cells and in rat and hamster insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenoma, Islet Cell; Adrenocort | 1986 |
Glucose stimulates insulin release without altering cyclic AMP production or inositolphospholipid turnover in freshly obtained human insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Carbachol; Colforsin; Cyclic AMP; Glucose; Humans; | 1987 |
Mechanisms of vasoactive intestinal peptide release in short-term culture of vasoactive intestinal peptide-producing tumor.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; | 1988 |
Structure, function, and immunogenicity of human insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Adult; C-Peptide; Fluorescent Antibody Technique; | 1988 |