1-methyl-3-isobutylxanthine has been researched along with Insulin Sensitivity in 11 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore the adaptive response of the endocrine pancreas in vivo and in vitro and the possible beneficial effect of the insulino-mimetic agent vanadyl sulfate (VOSO(4)), using glucocorticoid treatment to increase insulin resistance, in aging rats." | 7.71 | Dexamethasone-induced insulin resistance and pancreatic adaptive response in aging rats are not modified by oral vanadyl sulfate treatment. ( Barbera, M; Bergamini, E; Bombara, M; De Tata, V; Fierabracci, V; Masiello, P; Novelli, M, 2001) |
| "It has recently been shown that deficiency of adrenomedullin (AM), a potent vasodilator peptide, leads to insulin resistance." | 3.72 | Differential expression of adrenomedullin and resistin in 3T3-L1 adipocytes treated with tumor necrosis factor-alpha. ( Furuyama, K; Li, Y; Shibahara, S; Takahashi, K; Takeda, K; Totsune, K, 2003) |
| "To explore the adaptive response of the endocrine pancreas in vivo and in vitro and the possible beneficial effect of the insulino-mimetic agent vanadyl sulfate (VOSO(4)), using glucocorticoid treatment to increase insulin resistance, in aging rats." | 3.71 | Dexamethasone-induced insulin resistance and pancreatic adaptive response in aging rats are not modified by oral vanadyl sulfate treatment. ( Barbera, M; Bergamini, E; Bombara, M; De Tata, V; Fierabracci, V; Masiello, P; Novelli, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, J | 1 |
| Ahn, S | 2 |
| Kim, HJ | 1 |
| Lee, M | 1 |
| Kim, J | 1 |
| Jin, SH | 1 |
| Lee, E | 1 |
| Kim, G | 1 |
| Cheong, JH | 1 |
| Jacobson, KA | 1 |
| Jeong, LS | 1 |
| Noh, M | 1 |
| Nie, XQ | 1 |
| Yang, JW | 1 |
| Shi, HX | 1 |
| Zhang, YJ | 1 |
| Zhang, JY | 1 |
| Bian, K | 1 |
| Balbo, SL | 1 |
| Ribeiro, RA | 1 |
| Mendes, MC | 1 |
| Lubaczeuski, C | 1 |
| Maller, AC | 1 |
| Carneiro, EM | 1 |
| Bonfleur, ML | 1 |
| White, UA | 1 |
| Stewart, WC | 1 |
| Mynatt, RL | 1 |
| Stephens, JM | 1 |
| Kim Chung, le T | 1 |
| Hosaka, T | 1 |
| Yoshida, M | 1 |
| Harada, N | 1 |
| Sakaue, H | 1 |
| Sakai, T | 1 |
| Nakaya, Y | 1 |
| Li, Y | 1 |
| Totsune, K | 1 |
| Takeda, K | 1 |
| Furuyama, K | 1 |
| Shibahara, S | 1 |
| Takahashi, K | 1 |
| Kirsch, D | 1 |
| Kemmler, W | 1 |
| Häring, HU | 1 |
| Barbera, M | 1 |
| Fierabracci, V | 1 |
| Novelli, M | 1 |
| Bombara, M | 1 |
| Masiello, P | 1 |
| Bergamini, E | 1 |
| De Tata, V | 1 |
| Guerre-Millo, M | 1 |
| Rouault, C | 1 |
| Poulain, P | 1 |
| André, J | 1 |
| Poitout, V | 1 |
| Peters, JM | 1 |
| Gonzalez, FJ | 1 |
| Fruchart, JC | 1 |
| Reach, G | 1 |
| Staels, B | 1 |
| Solomon, SS | 1 |
| Heckemeyer, CM | 1 |
| Barker, JA | 1 |
| Duckworth, WC | 1 |
| Weir, GC | 1 |
| Leahy, JL | 1 |
| Bonner-Weir, S | 1 |
1 review available for 1-methyl-3-isobutylxanthine and Insulin Sensitivity
| Article | Year |
|---|---|
Experimental reduction of B-cell mass: implications for the pathogenesis of diabetes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Arginine; Blood Glucose; Cyclic AMP; Diabete | 1986 |
10 other studies available for 1-methyl-3-isobutylxanthine and Insulin Sensitivity
| Article | Year |
|---|---|
Polypharmacology of N
Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adiponectin; Animals; | 2017 |
[Establishment of a cell model of insulin-resistant 3T3-L1 adipocytes].
Topics: 1-Methyl-3-isobutylxanthine; 3T3-L1 Cells; Adipocytes; Animals; Cell Differentiation; Culture Media; | 2015 |
Vagotomy diminishes obesity in cafeteria rats by decreasing cholinergic potentiation of insulin release.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Body Weight; Carbachol; Colforsin; Cyclic AMP; | 2016 |
Neuropoietin attenuates adipogenesis and induces insulin resistance in adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adipocytes; Animals; Ciliary Neurotrophic Factor; Dexamethas | 2008 |
Exendin-4, a GLP-1 receptor agonist, directly induces adiponectin expression through protein kinase A pathway and prevents inflammatory adipokine expression.
Topics: 1-Methyl-3-isobutylxanthine; 3T3-L1 Cells; Adipocytes; Adipokines; Adiponectin; Animals; Colforsin; | 2009 |
Differential expression of adrenomedullin and resistin in 3T3-L1 adipocytes treated with tumor necrosis factor-alpha.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adipocytes; Adrenomedullin; Animals; Blotting, Northern; Cel | 2003 |
Cyclic AMP modulates insulin binding and induces post-receptor insulin resistance of glucose transport in isolated rat adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3-O-Methylglucose; 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tiss | 1983 |
Dexamethasone-induced insulin resistance and pancreatic adaptive response in aging rats are not modified by oral vanadyl sulfate treatment.
Topics: 1-Methyl-3-isobutylxanthine; Adaptation, Physiological; Adrenal Glands; Aging; Animals; Blood Glucos | 2001 |
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carbachol; Dietary Fats; Drug Synergism; Fastin | 2001 |
Hormonal control of lipolysis in perifused adipocytes from diabetic rats.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adipose Tissue; Animals; Diabetes Mellitus, Experimental; Ep | 1985 |