1-methyl-3-isobutylxanthine has been researched along with Hypertrophy, Right Ventricular in 3 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Hypertrophy, Right Ventricular: Enlargement of the RIGHT VENTRICLE of the heart. This increase in ventricular mass is often attributed to PULMONARY HYPERTENSION and is a contributor to cardiovascular morbidity and mortality.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crosswhite, P | 1 |
| Sun, Z | 1 |
| Hashimoto, T | 1 |
| Sugiyama, A | 1 |
| Taguchi, S | 1 |
| Schermuly, RT | 1 |
| Pullamsetti, SS | 1 |
| Kwapiszewska, G | 1 |
| Dumitrascu, R | 1 |
| Tian, X | 1 |
| Weissmann, N | 1 |
| Ghofrani, HA | 1 |
| Kaulen, C | 1 |
| Dunkern, T | 1 |
| Schudt, C | 1 |
| Voswinckel, R | 1 |
| Zhou, J | 1 |
| Samidurai, A | 1 |
| Klepetko, W | 1 |
| Paddenberg, R | 1 |
| Kummer, W | 1 |
| Seeger, W | 1 |
| Grimminger, F | 1 |
3 other studies available for 1-methyl-3-isobutylxanthine and Hypertrophy, Right Ventricular
| Article | Year |
|---|---|
Inhibition of phosphodiesterase-1 attenuates cold-induced pulmonary hypertension.
Topics: 1-Methyl-3-isobutylxanthine; Acetophenones; Animals; Cold Temperature; Cyclic Nucleotide Phosphodies | 2013 |
Myosin heavy chain isoforms expression and cyclic AMP concentrations in hypoxia-induced hypertrophied right ventricle in rats.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Altitude; Animals; Cell Membrane; Colforsin; Cyclic | 2004 |
Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cell Division; Chronic Di | 2007 |