1-methyl-3-isobutylxanthine has been researched along with Hypertrophy, Left Ventricular in 1 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Left ventricular hypertrophy was induced by a 50% constriction of suprarenal abdominal aorta for 6 weeks." | 1.33 | Cardiac hypertrophy diminished the effects of isoproterenol on delayed rectifier potassium current in rat heart. ( Mani, H; Matsubara, H; Sakatani, T; Shiraishi, H; Shirayama, T; Yamamoto, T, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sakatani, T | 1 |
| Shirayama, T | 1 |
| Yamamoto, T | 1 |
| Mani, H | 1 |
| Shiraishi, H | 1 |
| Matsubara, H | 1 |
1 other study available for 1-methyl-3-isobutylxanthine and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
Cardiac hypertrophy diminished the effects of isoproterenol on delayed rectifier potassium current in rat heart.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adrenergic beta-Agonists; Animals; Calcium Channels, | 2006 |