1-methyl-3-isobutylxanthine has been researched along with Hyperthyroidism in 3 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Hyperthyroidism: Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The half-maximal effective concentration (EC50) for the euthyroid isoproterenol dose-response curve is 2." | 1.28 | Hyperthyroid adult rat cardiomyocytes. I. Nucleotide content, beta- and alpha-adrenoreceptors, and cAMP production. ( Altschuld, RA; Brierley, GP; Fertel, RH; Hohl, CM; Wetzel, S; Wimsatt, DK, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elks, ML | 1 |
| Manganiello, VC | 1 |
| Müller, MJ | 1 |
| Seitz, HJ | 1 |
| Hohl, CM | 1 |
| Wetzel, S | 1 |
| Fertel, RH | 1 |
| Wimsatt, DK | 1 |
| Brierley, GP | 1 |
| Altschuld, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Thyroid Hormone-Induced Lipolysis: An In Vivo Microdialysis Study[NCT00312715] | 41 participants (Actual) | Observational | 2006-04-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for 1-methyl-3-isobutylxanthine and Hyperthyroidism
| Article | Year |
|---|---|
Effects of thyroid hormone on regulation of lipolysis and adenosine 3',5'-monophosphate metabolism in 3T3-L1 adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adipose Tissue; | 1985 |
Interrelation between thyroid state and the effect of glucagon on gluconeogenesis in perfused rat livers.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alanine; Aminoisobutyric Acids; An | 1987 |
Hyperthyroid adult rat cardiomyocytes. I. Nucleotide content, beta- and alpha-adrenoreceptors, and cAMP production.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; AMP Deaminase; Animals; Binding Si | 1989 |