1-methyl-3-isobutylxanthine has been researched along with Hyperinsulinism in 4 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When treatment with diazoxide and somatostatin for persistent hyperinsulinaemic hypoglycaemia of infancy failed, subtotal pancreatectomy was performed on a neonate on day 41." | 1.30 | Histochemical, clinical, and in vitro beta cell responses in a neonate with persistent hyperinsulinaemic hypoglycaemia of infancy. ( Hjelm, NM; Liew, CT; Panesar, NS; Poon, CW; Wong, GW, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balbo, SL | 1 |
| Ribeiro, RA | 1 |
| Mendes, MC | 1 |
| Lubaczeuski, C | 1 |
| Maller, AC | 1 |
| Carneiro, EM | 1 |
| Bonfleur, ML | 1 |
| Yelich, MR | 1 |
| Filkins, JP | 1 |
| Panesar, NS | 1 |
| Poon, CW | 1 |
| Liew, CT | 1 |
| Wong, GW | 1 |
| Hjelm, NM | 1 |
| Guerre-Millo, M | 1 |
| Rouault, C | 1 |
| Poulain, P | 1 |
| André, J | 1 |
| Poitout, V | 1 |
| Peters, JM | 1 |
| Gonzalez, FJ | 1 |
| Fruchart, JC | 1 |
| Reach, G | 1 |
| Staels, B | 1 |
4 other studies available for 1-methyl-3-isobutylxanthine and Hyperinsulinism
| Article | Year |
|---|---|
Vagotomy diminishes obesity in cafeteria rats by decreasing cholinergic potentiation of insulin release.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Body Weight; Carbachol; Colforsin; Cyclic AMP; | 2016 |
Role for calcium in the insulin hypersecretory state of the endotoxic rat pancreas.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Endotoxins; Glucose; Hyperinsulinism; Insulin; Insuli | 1984 |
Histochemical, clinical, and in vitro beta cell responses in a neonate with persistent hyperinsulinaemic hypoglycaemia of infancy.
Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Diazoxide; Diuretics; Glucose; Humans; Hyperinsulinism | 1998 |
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carbachol; Dietary Fats; Drug Synergism; Fastin | 2001 |