1-methyl-3-isobutylxanthine has been researched along with Graft vs Host Disease in 1 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Graft vs Host Disease: The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Shaughnessy, MJ | 1 |
| Chen, ZM | 1 |
| Gramaglia, I | 1 |
| Taylor, PA | 1 |
| Panoskaltsis-Mortari, A | 1 |
| Vogtenhuber, C | 1 |
| Palmer, E | 1 |
| Grader-Beck, T | 1 |
| Boussiotis, VA | 1 |
| Blazar, BR | 1 |
1 other study available for 1-methyl-3-isobutylxanthine and Graft vs Host Disease
| Article | Year |
|---|---|
Elevation of intracellular cyclic AMP in alloreactive CD4(+) T Cells induces alloantigen-specific tolerance that can prevent GVHD lethality in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Animals; CD4-Positive T-Lymphocytes; Cell Transplantation; Cyclic AMP; | 2007 |