1-methyl-3-isobutylxanthine has been researched along with Gastric Ulcer in 3 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The combined anti-inflammatory data from in vitro animal model showed that compounds, 9,11-dibromo-1-(2-furyl)-3-(4-tolyl)-8H-pyrido[2',3':4,5]pyrimido[6,1-b]quinazolin-8-one 23, 9,11-dibromo-1-(4-methoxy-phenyl)-3-phenyl-8H-pyrido[2',3':4,5]pyrimido[6,1-b]quinazolin-8-one 24, 9,11-dibromo-1-(4-chloro-phenyl)-3-(4-tolyl)-8H-pyrido[2',3':4,5]pyrimido[6,1-b]quinazolin-8-one 29 and 9-bromo-1-(4-chloro-phenyl)-3-(4-tolyl)-8H-pyrido[2',3':4,5]pyrimido[6,1-b]quinazolin-8-one 36 exhibited even more potent anti-inflammatory activity and low gastric ulceration incidence compare to reference standard Indomethacin." | 3.75 | A new therapeutic approach in Parkinson's disease: some novel quinazoline derivatives as dual selective phosphodiesterase 1 inhibitors and anti-inflammatory agents. ( Bhatnagar, SP; Laddha, SS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laddha, SS | 1 |
| Bhatnagar, SP | 1 |
| Haglund, U | 1 |
| Elander, B | 1 |
| Fellenius, E | 1 |
| Leth, R | 1 |
| Rehnberg, O | 1 |
| Olbe, L | 1 |
| Schepp, W | 1 |
| Miederer, SE | 1 |
| Ruoff, HJ | 1 |
3 other studies available for 1-methyl-3-isobutylxanthine and Gastric Ulcer
| Article | Year |
|---|---|
A new therapeutic approach in Parkinson's disease: some novel quinazoline derivatives as dual selective phosphodiesterase 1 inhibitors and anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Child, Preschool; Cyclic Nucleotide Phosphodiesterases, Type 1; D | 2009 |
The effects of secretagogues of isolated human gastric glands.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Aminopyrine; Bucladesine; Carbachol; Duodenal Ulcer; Gastr | 1982 |
Intrinsic factor secretion from isolated human gastric mucosal cells.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Carbachol; Female; Gastric Mucosa; Histamine; Humans; In V | 1984 |