Page last updated: 2024-10-29

1-methyl-3-isobutylxanthine and Epilepsy, Absence

1-methyl-3-isobutylxanthine has been researched along with Epilepsy, Absence in 1 studies

1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.

Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Budde, T1
Caputi, L1
Kanyshkova, T1
Staak, R1
Abrahamczik, C1
Munsch, T1
Pape, HC1

Other Studies

1 other study available for 1-methyl-3-isobutylxanthine and Epilepsy, Absence

ArticleYear
Impaired regulation of thalamic pacemaker channels through an imbalance of subunit expression in absence epilepsy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Oct-26, Volume: 25, Issue:43

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adenine; Ani

2005