Page last updated: 2024-10-29

1-methyl-3-isobutylxanthine and Compensatory Hyperinsulinemia

1-methyl-3-isobutylxanthine has been researched along with Compensatory Hyperinsulinemia in 4 studies

1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.

Compensatory Hyperinsulinemia: A GLUCOSE-induced HYPERINSULINEMIA, a marker of insulin-resistant state. It is a mechanism to compensate for reduced sensitivity to insulin.

Research Excerpts

ExcerptRelevanceReference
"When treatment with diazoxide and somatostatin for persistent hyperinsulinaemic hypoglycaemia of infancy failed, subtotal pancreatectomy was performed on a neonate on day 41."1.30Histochemical, clinical, and in vitro beta cell responses in a neonate with persistent hyperinsulinaemic hypoglycaemia of infancy. ( Hjelm, NM; Liew, CT; Panesar, NS; Poon, CW; Wong, GW, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balbo, SL1
Ribeiro, RA1
Mendes, MC1
Lubaczeuski, C1
Maller, AC1
Carneiro, EM1
Bonfleur, ML1
Yelich, MR1
Filkins, JP1
Panesar, NS1
Poon, CW1
Liew, CT1
Wong, GW1
Hjelm, NM1
Guerre-Millo, M1
Rouault, C1
Poulain, P1
André, J1
Poitout, V1
Peters, JM1
Gonzalez, FJ1
Fruchart, JC1
Reach, G1
Staels, B1

Other Studies

4 other studies available for 1-methyl-3-isobutylxanthine and Compensatory Hyperinsulinemia

ArticleYear
Vagotomy diminishes obesity in cafeteria rats by decreasing cholinergic potentiation of insulin release.
    Journal of physiology and biochemistry, 2016, Volume: 72, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Body Weight; Carbachol; Colforsin; Cyclic AMP;

2016
Role for calcium in the insulin hypersecretory state of the endotoxic rat pancreas.
    Circulatory shock, 1984, Volume: 14, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Endotoxins; Glucose; Hyperinsulinism; Insulin; Insuli

1984
Histochemical, clinical, and in vitro beta cell responses in a neonate with persistent hyperinsulinaemic hypoglycaemia of infancy.
    Archives of disease in childhood. Fetal and neonatal edition, 1998, Volume: 79, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Diazoxide; Diuretics; Glucose; Humans; Hyperinsulinism

1998
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
    Diabetes, 2001, Volume: 50, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carbachol; Dietary Fats; Drug Synergism; Fastin

2001