1-methyl-3-isobutylxanthine has been researched along with Colonic Neoplasms in 8 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A close dose-response relationship existed for forskolin and for cholera toxin between cAMP generation and carcinoembryonic antigen release." | 1.27 | Effects of cyclic adenosine 3':5'-monophosphate upon glycoprotein and carcinoembryonic antigen synthesis and release by human colon cancer cells. ( Hwang, WI; Kim, YS; Sack, TL, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hauri, HP | 1 |
| Sander, B | 1 |
| Naim, H | 1 |
| Tabcharani, JA | 1 |
| Boucher, A | 1 |
| Eng, JW | 1 |
| Hanrahan, JW | 1 |
| Velcich, A | 1 |
| Augenlicht, LH | 1 |
| Daneker, GW | 1 |
| Lund, SA | 1 |
| Caughman, SW | 1 |
| Staley, CA | 1 |
| Wood, WC | 1 |
| Gamet, L | 1 |
| Murat, JC | 1 |
| Remaury, A | 1 |
| Remesy, C | 1 |
| Valet, P | 1 |
| Paris, H | 1 |
| Denis-Pouxviel, C | 1 |
| Yedgar, S | 1 |
| Eidelman, O | 1 |
| Malden, E | 1 |
| Roberts, D | 1 |
| Etcheberrigaray, R | 1 |
| Goping, G | 1 |
| Fox, C | 1 |
| Pollard, HB | 1 |
| Champigny, G | 1 |
| Verrier, B | 1 |
| Lazdunski, M | 1 |
| Hwang, WI | 1 |
| Sack, TL | 1 |
| Kim, YS | 1 |
8 other studies available for 1-methyl-3-isobutylxanthine and Colonic Neoplasms
| Article | Year |
|---|---|
Induction of lactase biosynthesis in the human intestinal epithelial cell line Caco-2.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenocarcinoma; beta-Galactosid | 1994 |
Regulation of an inwardly rectifying K channel in the T84 epithelial cell line by calcium, nucleotides and kinases.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Bacterial Toxins; Calcium; Cell Membrane; Colon | 1994 |
Regulated expression of an intestinal mucin gene in HT29 colonic carcinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Bucladesine; Calcimycin; Colforsin; Colonic Neoplasms; | 1993 |
Anti-metastatic prostacyclins inhibit the adhesion of colon carcinoma to endothelial cells by blocking E-selectin expression.
Topics: 1-Methyl-3-isobutylxanthine; Antineoplastic Agents; Bucladesine; Carcinoma; Cell Adhesion; Cells, Cu | 1996 |
Vasoactive intestinal peptide and forskolin regulate proliferation of the HT29 human colon adenocarcinoma cell line.
Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Blood; Cell Division; Colforsin; Colonic Neoplasms; Cyc | 1992 |
Cyclic AMP-independent secretion of mucin by SW1116 human colon carcinoma cells. Differential control by Ca2+ ionophore A23187 and arachidonic acid.
Topics: 1-Methyl-3-isobutylxanthine; Arachidonic Acid; Calcimycin; Cell Line; Colforsin; Colonic Neoplasms; | 1992 |
A voltage, calcium, and ATP sensitive non selective cation channel in human colonic tumor cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Adenosine Triphosphate; Calcimycin; Calcium; Cell Line; | 1991 |
Effects of cyclic adenosine 3':5'-monophosphate upon glycoprotein and carcinoembryonic antigen synthesis and release by human colon cancer cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Carcinoembryoni | 1986 |