1-methyl-3-isobutylxanthine has been researched along with Chronic Disease in 2 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schermuly, RT | 1 |
| Pullamsetti, SS | 1 |
| Kwapiszewska, G | 1 |
| Dumitrascu, R | 1 |
| Tian, X | 1 |
| Weissmann, N | 1 |
| Ghofrani, HA | 1 |
| Kaulen, C | 1 |
| Dunkern, T | 1 |
| Schudt, C | 1 |
| Voswinckel, R | 1 |
| Zhou, J | 1 |
| Samidurai, A | 1 |
| Klepetko, W | 1 |
| Paddenberg, R | 1 |
| Kummer, W | 1 |
| Seeger, W | 1 |
| Grimminger, F | 1 |
| Asfaha, S | 1 |
| MacNaughton, WK | 1 |
| Appleyard, CB | 1 |
| Chadee, K | 1 |
| Wallace, JL | 1 |
2 other studies available for 1-methyl-3-isobutylxanthine and Chronic Disease
| Article | Year |
|---|---|
Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cell Division; Chronic Di | 2007 |
Persistent epithelial dysfunction and bacterial translocation after resolution of intestinal inflammation.
Topics: 1-Methyl-3-isobutylxanthine; Acute Disease; Animals; Bacteria, Aerobic; Bacterial Toxins; Bacterial | 2001 |