1-methyl-3-isobutylxanthine has been researched along with Choriocarcinoma in 4 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "These retinoid-treated choriocarcinoma cells remained responsive to 8BrcAMP or compounds that increase intracellular cAMP concentrations and to BrdUrd; the production to PS beta G and hCG was greatly stimulated by 8BrcAMP, cholera toxin, or MIX, and the production of hCG and hCG alpha was greatly inhibited by BrdUrd." | 1.26 | Effects of retinoic acid on differentiation of choriocarcinoma cells in vitro. ( Chou, JY, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chou, JY | 1 |
| Telfer, JF | 1 |
| Green, CD | 1 |
| King, SC | 1 |
| Tiller, AA | 1 |
| Chang, AS | 1 |
| Lam, DM | 1 |
| Cool, DR | 1 |
| Leibach, FH | 1 |
| Bhalla, VK | 1 |
| Mahesh, VB | 1 |
| Ganapathy, V | 1 |
4 other studies available for 1-methyl-3-isobutylxanthine and Choriocarcinoma
| Article | Year |
|---|---|
Effects of retinoic acid on differentiation of choriocarcinoma cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Cell Line; Cell Transformation, | 1982 |
Induction of germ-cell alkaline phosphatase by butyrate and cyclic AMP in BeWo choriocarcinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Bucladesine; Cell Line; Cholera Toxin; Choriocarc | 1993 |
Differential regulation of the imipramine-sensitive serotonin transporter by cAMP in human JAr choriocarcinoma cells, rat PC12 pheochromocytoma cells, and C33-14-B1 transgenic mouse fibroblast cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Cells, Cultured; Cholera Toxin; Choriocarcin | 1992 |
Expression and cyclic AMP-dependent regulation of a high affinity serotonin transporter in the human placental choriocarcinoma cell line (JAR).
Topics: 1-Methyl-3-isobutylxanthine; Antidepressive Agents; Biological Transport, Active; Bucladesine; Carri | 1991 |