Compounds > 1-methyl-3-isobutylxanthine
Page last updated: 2024-10-29

1-methyl-3-isobutylxanthine and Central Hypothyroidism

1-methyl-3-isobutylxanthine has been researched along with Central Hypothyroidism in 4 studies

1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hagino, Y1
Uematsu, T1
Tachibana, M1
Tsuru, H1
Elks, ML1
Manganiello, VC1
Al-Turk, WA1
Shaheen, O1
Othman, S1
Müller, MJ1
Seitz, HJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Thyroid Hormone-Induced Lipolysis: An In Vivo Microdialysis Study[NCT00312715]41 participants (Actual)Observational2006-04-03Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for 1-methyl-3-isobutylxanthine and Central Hypothyroidism

ArticleYear
Effect of thyroid hormone on cyclic AMP phosphodiesterase in rat kidney.
    Japanese journal of pharmacology, 1980, Volume: 30, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Hypothyroidism; In Vitro

1980
Effects of thyroid hormone on regulation of lipolysis and adenosine 3',5'-monophosphate metabolism in 3T3-L1 adipocytes.
    Endocrinology, 1985, Volume: 117, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adipose Tissue;

1985
Effect of forskolin on cAMP accumulation and ketogenesis in isolated hepatocytes.
    General pharmacology, 1986, Volume: 17, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Glucagon; Hypothyroidism; In Vitro Tech

1986
Interrelation between thyroid state and the effect of glucagon on gluconeogenesis in perfused rat livers.
    Biochemical pharmacology, 1987, May-15, Volume: 36, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alanine; Aminoisobutyric Acids; An

1987