1-methyl-3-isobutylxanthine has been researched along with Carcinoma, Small Cell in 6 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friedmann, AS | 1 |
| Fay, MJ | 1 |
| Memoli, VA | 1 |
| North, WG | 1 |
| Allam, M | 1 |
| Bertrand, R | 1 |
| Zhang-Sun, G | 1 |
| Pappas, J | 1 |
| Viallet, J | 2 |
| Maruno, K | 1 |
| Absood, A | 1 |
| Said, SI | 1 |
| Wittau, N | 1 |
| Grosse, R | 1 |
| Kalkbrenner, F | 1 |
| Gohla, A | 1 |
| Schultz, G | 1 |
| Gudermann, T | 1 |
| Kaur, G | 1 |
| Laborda, J | 1 |
| Blair, O | 1 |
| Gazdar, AF | 1 |
| Minna, JD | 1 |
| Sausville, EA | 1 |
| Verbeeck, MA | 1 |
| Sutanto, W | 1 |
| Burbach, JP | 1 |
6 other studies available for 1-methyl-3-isobutylxanthine and Carcinoma, Small Cell
| Article | Year |
|---|---|
Factors regulating the production of vasopressin-associated human neurophysin by small-cell carcinoma of the lung: evaluation by computer-enhanced quantitative immunocytochemistry.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Carcinoma, Small Cell; Colforsi | 1995 |
Cholera toxin triggers apoptosis in human lung cancer cell lines.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Apoptosis; bcl-2-Associated X Protein; Benzophenanthridines; | 1997 |
Vasoactive intestinal peptide inhibits human small-cell lung cancer proliferation in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Carcinoma, Small Cell; Cell Division; Colfo | 1998 |
The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Actin Cytoskeleton; Actins; Animals; Calcium Signaling; Carc | 2000 |
Growth inhibition by cholera toxin of human lung carcinoma cell lines: correlation with GM1 ganglioside expression.
Topics: 1-Methyl-3-isobutylxanthine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; C | 1992 |
Regulation of vasopressin messenger RNA levels in the small cell lung carcinoma cell line GLC-8: interactions between glucocorticoids and second messengers.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Aldosterone; Carcinoma, Small C | 1991 |