1-methyl-3-isobutylxanthine has been researched along with Bronchial Spasm in 2 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The contents of histamine and cyclic nucleotides were studied in leukocytes before and after a bronchoprovocation test on patients with extrinsic asthma." | 7.66 | Changes in histamine and cyclic nucleotide levels after bronchoprovocation in patients with extrinsic asthma. ( Andersson, RG; Brundin, A; Lindgren, BR, 1978) |
| "The contents of histamine and cyclic nucleotides were studied in leukocytes before and after a bronchoprovocation test on patients with extrinsic asthma." | 3.66 | Changes in histamine and cyclic nucleotide levels after bronchoprovocation in patients with extrinsic asthma. ( Andersson, RG; Brundin, A; Lindgren, BR, 1978) |
| " As a whole the pharmacodynamic profile of isbufylline is promising and, in the clinical setting, this compound might exert enhanced antiasthma effects coupled to a low incidence of central and cardiovascular adverse effects." | 1.28 | Pharmacodynamic profile of isbufylline, a new antibronchospastic xanthine devoid of central excitatory actions. ( Antonelli, T; Bacciarelli, C; Ballati, L; Beani, L; Borea, PA; Giachetti, A; Manzini, S; Meini, S, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lindgren, BR | 1 |
| Andersson, RG | 1 |
| Brundin, A | 1 |
| Manzini, S | 1 |
| Meini, S | 1 |
| Giachetti, A | 1 |
| Beani, L | 1 |
| Borea, PA | 1 |
| Antonelli, T | 1 |
| Ballati, L | 1 |
| Bacciarelli, C | 1 |
2 other studies available for 1-methyl-3-isobutylxanthine and Bronchial Spasm
| Article | Year |
|---|---|
Changes in histamine and cyclic nucleotide levels after bronchoprovocation in patients with extrinsic asthma.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Allergens; Asthma; Bronchial Spasm; Cyclic AMP; Cycl | 1978 |
Pharmacodynamic profile of isbufylline, a new antibronchospastic xanthine devoid of central excitatory actions.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anticonvulsants; Blood Pressure; Brain Chemistry; Bronchial Sp | 1990 |