1-methyl-3-isobutylxanthine has been researched along with Blood Pressure, High in 16 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dose-response curves of the strips from both strains for alpha-adrenoceptor stimulation with NA determined after pretreatment with CTX were comparable to those determined in the absence of timolol." | 1.27 | Role of stimulatory GTP-binding protein (Gs) in reduced beta-adrenoceptor coupling in the femoral artery of spontaneously hypertensive rats. ( Asano, M; Masuzawa, K; Matsuda, T, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 8 (50.00) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, D | 1 |
| Ren, J | 1 |
| Gillespie, DG | 1 |
| Mi, Z | 2 |
| Jackson, EK | 2 |
| Dubey, RK | 1 |
| Lu, C | 1 |
| Pribanic, S | 1 |
| Debonneville, A | 1 |
| Jiang, C | 1 |
| Rotin, D | 1 |
| Dusseau, JW | 1 |
| Hutchins, PM | 1 |
| Dean, T | 1 |
| Kornhauser, R | 1 |
| Papapetropoulos, A | 1 |
| Marczin, N | 1 |
| Snead, MD | 1 |
| Cheng, C | 1 |
| Milici, A | 1 |
| Catravas, JD | 1 |
| Bogoyevitch, MA | 1 |
| Fuller, SJ | 1 |
| Sugden, PH | 1 |
| Grove, KL | 1 |
| Gonçalves, J | 1 |
| Picard, S | 1 |
| Thibault, G | 1 |
| Deschepper, CF | 1 |
| McConnell, BK | 1 |
| Moravec, CS | 1 |
| Morano, I | 1 |
| Bond, M | 1 |
| Osaki, J | 1 |
| Haneda, T | 1 |
| Kashiwagi, Y | 1 |
| Oi, S | 1 |
| Fukuzawa, J | 1 |
| Sakai, H | 1 |
| Kikuchi, K | 1 |
| Hopf, A | 1 |
| Schreiber, R | 1 |
| Mall, M | 1 |
| Greger, R | 1 |
| Kunzelmann, K | 1 |
| Snyder, PM | 1 |
| Nishimura, Y | 1 |
| Usui, H | 1 |
| Suzuki, A | 1 |
| Kajimoto, N | 1 |
| Yamanishi, Y | 1 |
| Asano, M | 3 |
| Masuzawa, K | 3 |
| Matsuda, T | 3 |
| Asano, T | 1 |
16 other studies available for 1-methyl-3-isobutylxanthine and Blood Pressure, High
| Article | Year |
|---|---|
Regulation of 3',5'-cAMP in preglomerular smooth muscle and endothelial cells from genetically hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonist | 2010 |
The extracellular cAMP-adenosine pathway significantly contributes to the in vivo production of adenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cyclic AMP; Hypertension; Male; Rats; Rats, Inbred | 2007 |
The PY motif of ENaC, mutated in Liddle syndrome, regulates channel internalization, sorting and mobilization from subapical pool.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Motifs; Animals; Cell Line; Cell Membrane; Cyclic AMP; Endoc | 2007 |
Elevated arteriolar adenosine 3',5'-cyclic monophosphate production by SHR.
Topics: 1-Methyl-3-isobutylxanthine; Albuterol; Animals; Arterioles; Blood Pressure; Body Weight; Cyclic AMP | 1982 |
Increased platelet reactivity to prostaglandin E1 in hypertension is linked with altered signal transduction.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Blood Platelets; Colforsin; Cyclic AMP; GTP Phosp | 1993 |
Smooth muscle cell responsiveness to nitrovasodilators in hypertensive and normotensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Base Sequence; Blotting, Northern; Cells, Cultured; | 1994 |
cAMP and protein synthesis in isolated adult rat heart preparations.
Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Depende | 1993 |
Comparison of ANP binding and sensitivity in brains from hypertensive and normotensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Brain; Cyclic GMP; Guanylate Cyclas | 1997 |
Troponin I phosphorylation in spontaneously hypertensive rat heart: effect of beta-adrenergic stimulation.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl | 1997 |
Pressure-induced expression of heat shock protein 70 mRNA in adult rat heart is coupled both to protein kinase A-dependent and protein kinase C-dependent systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Pressure; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic AM | 1998 |
Cystic fibrosis transmembrane conductance regulator inhibits epithelial Na+ channels carrying Liddle's syndrome mutations.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antibodies; Calcium-Binding Proteins; Cyclic AMP-Dependent Pro | 1999 |
Liddle's syndrome mutations disrupt cAMP-mediated translocation of the epithelial Na(+) channel to the cell surface.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Cells, Cultured; Cyclic AMP; Cystic Fibr | 2000 |
Relaxant response of isolated basilar arteries to calcitonin gene-related peptide in stroke-prone spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Basilar Artery; Bucladesine; Calcitonin Gene-Re | 1992 |
Evidence for reduced beta-adrenoceptor coupling to adenylate cyclase in femoral arteries from spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bucladesine; Colforsin; Femoral Artery; Hyp | 1988 |
Reduced function of the stimulatory GTP-binding protein in beta adrenoceptor-adenylate cyclase system of femoral arteries isolated from spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bucladesine; Cholera Toxin; Colforsin; Cycl | 1988 |
Role of stimulatory GTP-binding protein (Gs) in reduced beta-adrenoceptor coupling in the femoral artery of spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Antagonists; Animals; Bucladesine; Cholera Toxin; Colf | 1988 |