1-methyl-3-isobutylxanthine has been researched along with Arthritis, Rheumatoid in 2 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Westhoff, CS | 1 |
| Freudiger, D | 1 |
| Petrow, P | 1 |
| Seyfert, C | 1 |
| Zacher, J | 1 |
| Kriegsmann, J | 1 |
| Pap, T | 1 |
| Gay, S | 1 |
| Stiehl, P | 1 |
| Gromnica-Ihle, E | 1 |
| Wernicke, D | 1 |
| Cho, ML | 1 |
| Kim, WU | 1 |
| Min, SY | 1 |
| Min, DJ | 1 |
| Min, JK | 1 |
| Lee, SH | 1 |
| Park, SH | 1 |
| Cho, CS | 1 |
| Kim, HY | 1 |
2 other studies available for 1-methyl-3-isobutylxanthine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Characterization of collagenase 3 (matrix metalloproteinase 13) messenger RNA expression in the synovial membrane and synovial fibroblasts of patients with rheumatoid arthritis.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoi | 1999 |
Cyclosporine differentially regulates interleukin-10, interleukin-15, and tumor necrosis factor a production by rheumatoid synoviocytes.
Topics: 1-Methyl-3-isobutylxanthine; Antimetabolites; Antirheumatic Agents; Arthritis, Rheumatoid; Bucladesi | 2002 |