1-methyl-3-isobutylxanthine has been researched along with Anesthesia in 7 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aims of this study were to determine whether a relationship exists between the occurrence of coronary artery occlusion-induced arrhythmias in the anaesthetized rat and the levels of cyclic AMP and cyclic GMP in both normal and ischaemic myocardium, and to assess whether such arrhythmias were modified by pretreatment with the phosphodiesterase inhibitors, quazodine and isobutyl methylxanthine (IBMX), or with the butyryl derivatives of cyclic AMP and cyclic GMP." | 3.67 | The relationship between coronary artery occlusion-induced arrhythmias and myocardial cyclic nucleotide levels in the anaesthetized rat. ( Kane, KA; Morcillo-Sanchez, EJ; Parratt, JR; Rodger, IW; Shahid, M, 1985) |
| " SCH23390 (3-30 nmol), a selective D-1 DA receptor antagonist, caused a progressive parallel shift to the right in the dose-response curve for DA-induced pancreatic secretion without changes in the maximal response." | 1.28 | Do D-1 dopamine receptors mediate dopamine-induced pancreatic exocrine secretion in anesthetized dogs? ( Chiba, S; Horiuchi, A; Iwatsuki, K; Yonekura, H, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avendano, CE | 1 |
| Billman, GE | 1 |
| Horiuchi, A | 2 |
| Iwatsuki, K | 2 |
| Ren, LM | 1 |
| Kuroda, T | 1 |
| Chiba, S | 2 |
| Mori, M | 1 |
| Tsushima, H | 1 |
| Matsuda, T | 1 |
| Hegde, SS | 1 |
| Lokhandwala, MF | 1 |
| Yonekura, H | 1 |
| Holbrook, M | 1 |
| Coker, SJ | 1 |
| Kane, KA | 1 |
| Morcillo-Sanchez, EJ | 1 |
| Parratt, JR | 1 |
| Rodger, IW | 1 |
| Shahid, M | 1 |
7 other studies available for 1-methyl-3-isobutylxanthine and Anesthesia
| Article | Year |
|---|---|
Effect of interventions that increase cyclic AMP levels on susceptibility to ventricular fibrillation in unanesthetized dogs.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Anesthesia; | 1994 |
Dual actions of glucagon: direct stimulation and indirect inhibition of dog pancreatic secretion.
Topics: 1-Methyl-3-isobutylxanthine; Anesthesia; Animals; Bicarbonates; Dogs; Dose-Response Relationship, Dr | 1993 |
Antidiuretic effects of dibutyryl-cyclic AMP microinjected into the hypothalamic paraventricular nucleus in a water-loaded and ethanol-anesthetized rat.
Topics: 1-Methyl-3-isobutylxanthine; Anesthesia; Animals; Atropine; Blood Pressure; Bucladesine; Cyclic AMP; | 1986 |
Involvement of cyclic-AMP in the hypotensive response to fenoldopam but not to quinpirole in the anaesthetized rat.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Anesthesia; Animals; Benzazepines; Blood Pressure; Cycli | 1988 |
Do D-1 dopamine receptors mediate dopamine-induced pancreatic exocrine secretion in anesthetized dogs?
Topics: 1-Methyl-3-isobutylxanthine; Anesthesia; Animals; Benzazepines; Cyclic AMP; Dogs; Dopamine; Ergoline | 1989 |
Comparison of the effects of isobutylmethylxanthine and milrinone on ischaemia-induced arrhythmias and platelet aggregation in anaesthetized rabbits.
Topics: 1-Methyl-3-isobutylxanthine; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bloo | 1989 |
The relationship between coronary artery occlusion-induced arrhythmias and myocardial cyclic nucleotide levels in the anaesthetized rat.
Topics: 1-Methyl-3-isobutylxanthine; Anesthesia; Animals; Arrhythmias, Cardiac; Bucladesine; Coronary Diseas | 1985 |