1-methyl-3-isobutylxanthine has been researched along with Aging in 52 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore the adaptive response of the endocrine pancreas in vivo and in vitro and the possible beneficial effect of the insulino-mimetic agent vanadyl sulfate (VOSO(4)), using glucocorticoid treatment to increase insulin resistance, in aging rats." | 7.71 | Dexamethasone-induced insulin resistance and pancreatic adaptive response in aging rats are not modified by oral vanadyl sulfate treatment. ( Barbera, M; Bergamini, E; Bombara, M; De Tata, V; Fierabracci, V; Masiello, P; Novelli, M, 2001) |
| "The effects and mechanisms of aging on corticosterone secretion in zona fasciculata-reticularis (ZFR) cells of ovariectomized (Ovx) rats were studied." | 7.71 | Involvement of cAMP but not PKA in the increase of corticosterone secretion in rat zona fasciculata-reticularis cells by aging. ( Lo, MJ; Wang, PS, 2002) |
| "These results suggest that the aging effects on the production of corticosterone in rat ZFR cells is associated with change of the generation of cAMP, the activity of 11 beta-hydroxylase and the protein expression of PRL receptor." | 7.70 | Aging effects on the secretion of corticosterone in male rats. ( Cho, WL; Kau, MM; Lo, MJ; Wang, PS, 2000) |
| "To explore the adaptive response of the endocrine pancreas in vivo and in vitro and the possible beneficial effect of the insulino-mimetic agent vanadyl sulfate (VOSO(4)), using glucocorticoid treatment to increase insulin resistance, in aging rats." | 3.71 | Dexamethasone-induced insulin resistance and pancreatic adaptive response in aging rats are not modified by oral vanadyl sulfate treatment. ( Barbera, M; Bergamini, E; Bombara, M; De Tata, V; Fierabracci, V; Masiello, P; Novelli, M, 2001) |
| "The effects and mechanisms of aging on corticosterone secretion in zona fasciculata-reticularis (ZFR) cells of ovariectomized (Ovx) rats were studied." | 3.71 | Involvement of cAMP but not PKA in the increase of corticosterone secretion in rat zona fasciculata-reticularis cells by aging. ( Lo, MJ; Wang, PS, 2002) |
| "These results suggest that the aging effects on the production of corticosterone in rat ZFR cells is associated with change of the generation of cAMP, the activity of 11 beta-hydroxylase and the protein expression of PRL receptor." | 3.70 | Aging effects on the secretion of corticosterone in male rats. ( Cho, WL; Kau, MM; Lo, MJ; Wang, PS, 2000) |
| " The influence of aging on the relaxant response and the change in cyclic nucleotide content induced by vasoactive intestinal polypeptide (VIP), nitric oxide (NO), electrical field stimulation of the non-adrenergic non-cholinergic neurones and substances acting at different levels of the cyclic AMP and cyclic GMP transduction pathways was studied in longitudinal muscle strips of the rat gastric fundus." | 3.69 | Influence of age on the signal transduction pathway of non-adrenergic non-cholinergic neurotransmitters in the rat gastric fundus. ( Lefebvre, RA; Smits, GJ, 1995) |
| " The characteristics of individual dose-response curves were compared according to the breed, season of birth and testicular weight of the lambs." | 1.29 | Secretion of transferrin in ovine seminiferous tubule cell cultures in response to FSH: influence of breed, season of birth and age of lambs. ( Fontaine, I; Monet-Kuntz, C, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (21.15) | 18.7374 |
| 1990's | 28 (53.85) | 18.2507 |
| 2000's | 10 (19.23) | 29.6817 |
| 2010's | 3 (5.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharpe, EJ | 1 |
| Larson, ED | 1 |
| Proenza, C | 1 |
| Bellinger, DL | 1 |
| Silva, D | 1 |
| Millar, AB | 1 |
| Molinaro, C | 1 |
| Ghamsary, M | 1 |
| Carter, J | 1 |
| Perez, S | 1 |
| Lorton, D | 1 |
| Lubahn, C | 1 |
| Araujoa, G | 1 |
| Thyagarajan, S | 1 |
| Chau, KM | 1 |
| Cornwall, GA | 1 |
| Takahashi, Y | 1 |
| Izumi, Y | 1 |
| Kohno, M | 1 |
| Kawamura, M | 1 |
| Ikeda, E | 1 |
| Nomori, H | 1 |
| Baamonde, C | 1 |
| Lumbreras, MA | 1 |
| MartInez-Cué, C | 1 |
| Vallina, IF | 1 |
| Flórez, J | 1 |
| Dierssen, M | 3 |
| Lo, MJ | 3 |
| Kau, MM | 2 |
| Wang, PS | 3 |
| Williams, JM | 1 |
| White, CR | 1 |
| Chang, MM | 1 |
| Injeti, ER | 1 |
| Zhang, L | 1 |
| Pearce, WJ | 1 |
| Slaughter, GR | 1 |
| Means, AR | 1 |
| Akita, T | 2 |
| Joyner, RW | 2 |
| Lu, C | 1 |
| Kumar, R | 2 |
| Hartzell, HC | 1 |
| Armstead, WM | 1 |
| Zuckerman, SL | 1 |
| Shibata, M | 1 |
| Parfenova, H | 1 |
| Leffler, CW | 1 |
| Howl, J | 1 |
| Rudge, SA | 1 |
| Lavis, RA | 1 |
| Davies, AR | 1 |
| Parslow, RA | 1 |
| Hughes, PJ | 1 |
| Kirk, CJ | 1 |
| Michell, RH | 1 |
| Wheatley, M | 1 |
| Smits, GJ | 1 |
| Lefebvre, RA | 1 |
| Bombara, M | 4 |
| Masiello, P | 4 |
| Novelli, M | 4 |
| Bergamini, E | 4 |
| Tolli, R | 1 |
| Monaco, L | 1 |
| Di Bonito, P | 1 |
| Canipari, R | 1 |
| Cuttler, L | 1 |
| Collins, BJ | 1 |
| Marone, PA | 1 |
| Szabo, M | 1 |
| Mulderry, PK | 1 |
| Simmons, KE | 1 |
| Jones, DJ | 1 |
| Lewis, DS | 1 |
| Soderstrom, PG | 1 |
| Monet-Kuntz, C | 1 |
| Fontaine, I | 1 |
| Kajiyama, Y | 1 |
| Sanai, Y | 1 |
| Ui, M | 1 |
| Knudsen, JH | 1 |
| Christensen, NJ | 1 |
| Bratholm, P | 1 |
| Brockway, PD | 1 |
| Hardin, JA | 1 |
| Gall, DG | 1 |
| Tanaka, J | 1 |
| Markerink-van Ittersum, M | 1 |
| Steinbusch, HW | 1 |
| De Vente, J | 1 |
| Klingler, C | 1 |
| Preisser, L | 1 |
| Barrault, MB | 1 |
| Lluel, P | 1 |
| Horgen, L | 1 |
| Teillet, L | 1 |
| Ancellin, N | 1 |
| Corman, B | 1 |
| Kanai, AJ | 1 |
| Mesaros, S | 1 |
| Finkel, MS | 1 |
| Oddis, CV | 1 |
| Birder, LA | 1 |
| Malinski, T | 1 |
| Noguchi, K | 1 |
| Tanaka, H | 1 |
| Shigenobu, K | 2 |
| Cadet, N | 1 |
| Paquin, J | 1 |
| De Tata, V | 2 |
| Cho, WL | 1 |
| Schutzer, WE | 1 |
| Xue, H | 1 |
| Reed, JF | 1 |
| Roullet, JB | 1 |
| Anderson, S | 1 |
| Mader, SL | 1 |
| Barbera, M | 1 |
| Fierabracci, V | 2 |
| Steinberger, A | 1 |
| Hintz, M | 1 |
| Heindel, JJ | 1 |
| Màrmol, F | 2 |
| Vivas, NM | 2 |
| Clos, MV | 2 |
| Badia, A | 2 |
| Villa, I | 1 |
| Guidobono, F | 1 |
| Netti, C | 1 |
| Pecile, A | 1 |
| Giovanazzi, S | 1 |
| Nicosia, S | 1 |
| Foged, N | 1 |
| Bertelsen, H | 1 |
| Johansen, T | 1 |
| Kazanietz, MG | 1 |
| Enero, MA | 1 |
| Gesek, FA | 1 |
| Schoolwerth, AC | 1 |
| Sato-Bigbee, C | 1 |
| Yu, RK | 1 |
| Gascón, S | 1 |
| Tsuchiyama, S | 1 |
| Tanigawa, K | 1 |
| Kato, Y | 1 |
| Draznin, B | 2 |
| Steinberg, JP | 1 |
| Leitner, JW | 2 |
| Sussman, KE | 2 |
| Bromberg, BB | 1 |
| Cripps, MM | 1 |
| Welch, MH | 1 |
| Goodman, M | 1 |
| Tsujimoto, G | 1 |
| Lee, CH | 1 |
| Hoffman, BB | 1 |
| Dumas, MY | 1 |
| Fanidi, A | 1 |
| Pageaux, JF | 1 |
| Courion, C | 1 |
| Nemoz, G | 1 |
| Prigent, AF | 1 |
| Pacheco, H | 1 |
| Laugier, C | 1 |
| Wang, SY | 1 |
| Rowe, JW | 1 |
| Wanstall, JC | 1 |
| O'Donnell, SR | 1 |
| Zeng, XP | 1 |
| Nakazawa, K | 1 |
| Kusuya, Y | 1 |
| Sato, M | 1 |
| Abe, K | 1 |
| Takeuchi, K | 1 |
| Yasujima, M | 1 |
| Hiwatari, M | 1 |
| Omata, K | 1 |
| Kasai, Y | 1 |
| Kudo, K | 1 |
| Kanazawa, M | 1 |
| Yoshida, K | 1 |
52 other studies available for 1-methyl-3-isobutylxanthine and Aging
| Article | Year |
|---|---|
Cyclic AMP reverses the effects of aging on pacemaker activity and If in sinoatrial node myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Aging; Animals; Cardiotonic Agents; Cells, Cultured; | 2017 |
Sympathetic nervous system and lymphocyte proliferation in the Fischer 344 rat spleen: a longitudinal study.
Topics: 1-Methyl-3-isobutylxanthine; Aging; alpha-Methyltyrosine; Animals; Concanavalin A; Cyclic AMP; Cytok | 2008 |
Reduced fertility in vitro in mice lacking the cystatin CRES (cystatin-related epididymal spermatogenic): rescue by exposure of spermatozoa to dibutyryl cAMP and isobutylmethylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Bucladesine; Cells, Cultured; Cystatins; Female; Gene E | 2011 |
Airway administration of dexamethasone, 3'-5'-cyclic adenosine monophosphate, and isobutylmethylxanthine facilitates compensatory lung growth in adult mice.
Topics: 1-Methyl-3-isobutylxanthine; Administration, Intranasal; Aging; Animals; Blotting, Western; Cyclic A | 2011 |
Postnatal handling induces long-term modifications in central beta-noradrenergic signalling in rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Cerebellum; | 2002 |
Effect of aging on corticosterone secretion in diestrous rats.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Ag | 2006 |
Chronic hypoxic decreases in soluble guanylate cyclase protein and enzyme activity are age dependent in fetal and adult ovine carotid arteries.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Carotid Arteries; Cyclic GMP; Cyclic GMP-Dependent Prot | 2006 |
Follicle-stimulating hormone activation of glycogen phosphorylase in the Sertoli cell-enriched rat testis.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Aging; Animals; Calcimycin; Cel | 1983 |
Developmental changes in modulation of calcium currents of rabbit ventricular cells by phosphodiesterase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Animals, Newborn; Calcium; Dose-Response Relationship, | 1994 |
Different pial arteriolar responses to acetylcholine in the newborn and juvenile pig.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Aging; Animals; Animals, Newborn; Arginine; Arterioles; | 1994 |
Rat testicular myoid cells express vasopressin receptors: receptor structure, signal transduction, and developmental regulation.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Amino Acid Sequence; Animals; Arginine Vasopr | 1995 |
Influence of age on the signal transduction pathway of non-adrenergic non-cholinergic neurotransmitters in the rat gastric fundus.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Analysis of Variance; Animals; Colforsin; Cyclic AMP; Cyclic GMP | 1995 |
Developmental changes in modulation of contractility of rabbit hearts.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Blood Pressure; Co | 1995 |
Impairment of the priming effect of glucose on insulin secretion from isolated islets of aging rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arginine; Blood Glucose; Glucose; In Vitro Techniques; | 1995 |
Hormonal regulation of urokinase- and tissue- type plasminogen activator in rat Sertoli cells.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Blotting, Northern; Bucladesine; Cells, Cultured; Cyclo | 1995 |
The effect of isobutylmethylxanthine, forskolin, and cholera toxin on growth hormone release from pituitary cell cultures of perinatal and mature rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Animals, Newborn; Cells, Cultured; Cholera Toxin; Colfo | 1993 |
Synergistic regulation of vasoactive intestinal polypeptide expression by cyclic AMP and calcium in newborn but not adult rat sensory neurons in culture.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl | 1993 |
6-Hydroxydopamine treatment of neonatal rats. I. Effects on the development of the spinal cord noradrenergic system.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Animals, Newborn; Cyclic AMP; Dihydroalprenolol; In Vit | 1993 |
In vivo and in vitro development of visceral adipose tissue in a nonhuman primate (Papio species).
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Aging; Analysis of Variance; Animals; Cell Differentiat | 1993 |
Secretion of transferrin in ovine seminiferous tubule cell cultures in response to FSH: influence of breed, season of birth and age of lambs.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Cells, Cultured; Follicle Stimulating Hormone; Male; Se | 1993 |
A role of asialoglycoproteins for plasma-membrane-induced inhibition of the switching from alpha 1 to beta subtypes in adrenergic response during primary culture of rat hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; As | 1996 |
Lymphocyte norepinephrine and epinephrine, but not plasma catecholamines predict lymphocyte cAMP production.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Aged, 80 and over; Aging; Cyclic AMP; Epinephrine; Humans; | 1996 |
Intestinal secretory response to atrial natriuretic peptide during postnatal development in the rabbit.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Atrial Natriuretic Factor; Chlorides; Cyclic GMP; Elect | 1996 |
Nitric oxide-mediated cGMP synthesis in oligodendrocytes in the developing rat brain.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Aging; Animals; Atrial Natr | 1997 |
Vasopressin V2 receptor mRNA expression and cAMP accumulation in aging rat kidney.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Angiotensin II; Animals; Chick Embryo; Cyclic AMP; Dehydration; | 1997 |
Beta-adrenergic regulation of constitutive nitric oxide synthase in cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl | 1997 |
Myocardial action potential prolongation by calcium channel activation under calcium free-EGTA conditions in guinea-pigs: developmental and regional variations.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adrenergic b | 1997 |
Conversion and storage of somatostatin are established before response to secretagogue stimuli in P19 neurons.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Carcinogens; Cell Differentiation; Central Nervous Syst | 2000 |
Age-dependent reduction in GLUT-2 levels is correlated with the impairment of the insulin secretory response in isolated islets of Sprague-Dawley rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Glucose Transporter Type 2; Insulin; Insulin Secretion; | 2000 |
Aging effects on the secretion of corticosterone in male rats.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Ag | 2000 |
Angiotensin II enhances beta-adrenergic receptor-mediated vasorelaxation in aortas from young but not old rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Aging; Angiotensin II; Animals; Aorta, Thorac | 2000 |
Dexamethasone-induced insulin resistance and pancreatic adaptive response in aging rats are not modified by oral vanadyl sulfate treatment.
Topics: 1-Methyl-3-isobutylxanthine; Adaptation, Physiological; Adrenal Glands; Aging; Animals; Blood Glucos | 2001 |
Involvement of cAMP but not PKA in the increase of corticosterone secretion in rat zona fasciculata-reticularis cells by aging.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Adrenocortic | 2002 |
Changes in cyclic AMP responses to FSH in isolated rat Sertoli cells during sexual maturation.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Cells, Cultured; Cyclic AMP; Follicle Stimulating Hormo | 1978 |
Post-train administration of 9-amino-1,2,3,4-tetrahydroacridine enhances passive avoidance retention and decreases beta-adrenoceptor-linked cyclic AMP formation in middle-aged rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Avoidance Learning; Cerebral Cortex; Conditioning, Psyc | 1992 |
Decrease in rat brain calcitonin binding sites and adenylyl-cyclase activity during ageing.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Animals; Autoradiography; Brain; Calcitonin; | 1992 |
Beta-adrenoceptor responsiveness in intact leukocytes from adults and newborn infants; effect of phosphodiesterase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Aging; Cyclic AMP; Humans; | 1990 |
Effects of different regimens of dietary restriction on the age-related decline in insulin secretory response of isolated rat pancreatic islets.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arginine; Diet, Reducing; Energy Intake; Glucose; In Vi | 1991 |
Decreased beta-adrenoceptor-mediated vasodilation in aorta from aged rats: possible involvement of a stimulatory GTP-binding protein.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Animals; Aorta; Clenbuterol; Colforsin; Cycli | 1991 |
Hormone responses of proximal Na(+)-H+ exchanger in spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Aging; Amiloride; Angiotensin II; Animals; A | 1991 |
Phosphorylation of nuclear proteins in myelinating oligodendrocytes and its control by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Aging; Animals; Brain; Cyclic AMP; Kinetics; Mo | 1991 |
Acute effects of tetrahydroaminoacridine on beta-adrenoceptor-linked cyclic AMP accumulation in brain of young and middle-aged rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Brain; Cerebral Cortex; Cholinesterase Inhibitors; Cycl | 1991 |
Effect of aging on the sensitivity of pancreatic beta-cells to insulin secretagogues in rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Blood Glucose; Female; Glucose; Insulin; Insulin Secret | 1991 |
The nature of insulin secretory defect in aging rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Exocytosis; Glucose; Glyburide; Glyceraldehyde; Insulin | 1985 |
Sympathomimetic protein secretion by young and aged lacrimal gland.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Cyclic AMP; Isoenzymes; Isoproterenol; Lacrimal Apparat | 1986 |
Insulin secretion in aging: studies with sequential gating of secretion vesicle margination and lysis.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Cytoplasmic Granules; Glucose; In Vitro Techniques; Ins | 1986 |
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Aging; B | 1986 |
Cyclic nucleotide phosphodiesterase activity in the quail oviduct: hormonal regulation and involvement in estrogen-induced growth.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterase | 1988 |
Age-related impairment in the short term regulation of insulin biosynthesis by glucose in rat pancreatic islets.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Aging; Animals; Dactinomycin; E | 1988 |
Age-dependence of the effects of pinacidil on rat aorta.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Aorta, Thoracic; Guanidines; In Vitro Techniques; Male; | 1989 |
Developmental increase in the inotropic and cyclic AMP response to isoproterenol in embryonic and newly hatched chicks.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Animals, Newborn; Chick Embryo; Chickens; Cyclic AMP; I | 1989 |
PGE2 synthesis in cultured renal papillary collecting tubule cells from young and aged spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Ca | 1989 |