1-methyl-3-isobutylxanthine has been researched along with Acute Respiratory Distress Syndrome in 3 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with indomethacin attenuated the increase in Kf after 65% triolein but not after 99% triolein." | 1.30 | Triolein-induced pulmonary embolization and increased microvascular permeability in isolated perfused rat lungs. ( Kuwagata, Y; Nakata, Y; Sugimoto, H; Tanaka, H; Yoshioka, T, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sheridan, BC | 1 |
| McIntyre, RC | 1 |
| Meldrum, DR | 1 |
| Fullerton, DA | 1 |
| Nakata, Y | 1 |
| Tanaka, H | 1 |
| Kuwagata, Y | 1 |
| Yoshioka, T | 1 |
| Sugimoto, H | 1 |
| Riva, CM | 1 |
| Morganroth, ML | 1 |
| Ljungman, AG | 1 |
| Schoeneich, SO | 1 |
| Marks, RM | 1 |
| Todd, RF | 1 |
| Ward, PA | 1 |
| Boxer, LA | 1 |
3 other studies available for 1-methyl-3-isobutylxanthine and Acute Respiratory Distress Syndrome
| Article | Year |
|---|---|
Phosphodiesterase inhibition overcomes pulmonary vasomotor dysfunction in acute lung injury.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Cyclic GMP; Endothelium, Vascular; Endotoxins; Mal | 1997 |
Triolein-induced pulmonary embolization and increased microvascular permeability in isolated perfused rat lungs.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Pressure; Capillary Permeability; Cyclooxygenase Inhibit | 1999 |
Iloprost inhibits neutrophil-induced lung injury and neutrophil adherence to endothelial monolayers.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclase Inhibitors; Animals; Cell Adhesion; Cyclic AM | 1990 |