Page last updated: 2024-08-26

1-methyl-1,2,3,4-tetrahydroisoquinoline and Parkinsonian Disorders

1-methyl-1,2,3,4-tetrahydroisoquinoline has been researched along with Parkinsonian Disorders in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Abe, K; Chiba, T; Ishikawa, R; Kambe, T; Munakata, H; Saitoh, T; Taguchi, K1
Antkiewicz-Michaluk, L; Michaluk, J; Nalepa, I; Romańska, I; Wąsik, A; Zelek-Molik, A1
Antkiewicz-Michaluk, L; Romańska, I; Wąsik, A1
Antkiewicz-Michaluk, L; Michaluk, J; Polak, D; Romańska, I; Wąsik, A1
Kotake, Y; Ohta, S; Okuda, K2
Fujitani, M; Kotake, Y; Makino, Y; Ohta, S; Shintani, H; Yamakawa, T1
Abe, K; Miyatake, T; Ren, J; Sano, T; Shinohara, T; Taguchi, K; Utsunomiya, I; Wasai, T1
Abe, K; Ishiwata, K; Kawamura, K; Koyanagi, Y; Saitoh, T; Sano, T; Senda, M; Taguchi, K; Toda, J1

Other Studies

9 other study(ies) available for 1-methyl-1,2,3,4-tetrahydroisoquinoline and Parkinsonian Disorders

ArticleYear
Preventative effects of 1-methyl-1,2,3,4-tetrahydroisoquinoline derivatives (
    Canadian journal of physiology and pharmacology, 2022, Jul-01, Volume: 100, Issue:7

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Humans; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neuroprotective Agents; Parkinsonian Disorders; Tetrahydroisoquinolines

2022
Neuroprotective Effect of the Endogenous Amine 1MeTIQ in an Animal Model of Parkinson's Disease.
    Neurotoxicity research, 2016, Volume: 29, Issue:3

    Topics: Animals; Brain; Corpus Striatum; Disease Models, Animal; Dopamine; Hyperkinesis; Male; Neuroprotective Agents; Parkinson Disease; Parkinsonian Disorders; Rats; Rats, Wistar; Tetrahydroisoquinolines

2016
Comparison of the Effects of Acute and Chronic Administration of Tetrahydroisoquinoline Amines on the In Vivo Dopamine Release: A Microdialysis Study in the Rat Striatum.
    Neurotoxicity research, 2016, Volume: 30, Issue:4

    Topics: Animals; Corpus Striatum; Dopamine; Dopamine Agents; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Parkinsonian Disorders; Rats, Wistar; Tetrahydroisoquinolines; Time Factors

2016
The impact of 1MeTIQ on the dopaminergic system function in the 6-OHDA model of Parkinson's disease.
    Pharmacological reports : PR, 2016, Volume: 68, Issue:6

    Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Male; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Substantia Nigra; Tetrahydroisoquinolines

2016
Determination method of 1-methyl-1,2,3, 4-tetrahydroisoquinoline, an endogenous parkinsonism-preventing substance, by radioimmunoassay.
    Life sciences, 2002, May-03, Volume: 70, Issue:24

    Topics: Animals; Antibody Formation; Blotting, Western; Brain Chemistry; Dopamine Antagonists; Female; Haptens; Immune Sera; Isoquinolines; Male; Parkinsonian Disorders; Rabbits; Radioimmunoassay; Rats; Rats, Wistar; Sensitivity and Specificity; Serum Albumin, Bovine; Tetrahydroisoquinolines; Time Factors

2002
Parkinsonism-preventing activity of 1-methyl-1,2,3,4-tetrahydroisoquinoline derivatives in C57BL mouse in vivo.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:7

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Brain; Dopamine; Dopamine Antagonists; Mice; Mice, Inbred C57BL; Parkinsonian Disorders; Tetrahydroisoquinolines

2006
Regional distribution of parkinsonism-preventing endogenous tetrahydroisoquinoline derivatives and an endogenous parkinsonism-preventing substance-synthesizing enzyme in monkey brain.
    Neuroscience letters, 1999, Nov-26, Volume: 276, Issue:1

    Topics: Animals; Brain; Isoquinolines; Macaca fascicularis; Parkinsonian Disorders; Tetrahydroisoquinolines; Tissue Distribution

1999
Stereoselective effect of (R)- and (S)-1-methyl-1,2,3,4-tetrahydroisoquinolines on a mouse model of Parkinson's disease.
    Brain research bulletin, 2001, Sep-01, Volume: 56, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Cell Count; Disease Models, Animal; Dopamine; Dopamine Antagonists; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypokinesia; Immunohistochemistry; Isoquinolines; Levodopa; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Neurotoxins; Parkinsonian Disorders; Serotonin; Stereoisomerism; Substantia Nigra; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase

2001
Evaluation of neurotoxicity of TIQ and MPTP and of parkinsonism-preventing effect of 1-MeTIQ by in vivo measurement of pre-synaptic dopamine transporters and post-synaptic dopamine D(2) receptors in the mouse striatum.
    Journal of neurochemistry, 2001, Volume: 79, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Hypokinesia; Isoquinolines; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Parkinsonian Disorders; Radioligand Assay; Receptors, Dopamine D2; Stereoisomerism; Substantia Nigra; Synapses; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase; Up-Regulation

2001