1-hydroxyprevitamin-d3 and Glomerulonephritis

Comparative assessment of the action of vitamin D2 in high doses, of oxydevit and rocaltrol applied in renal osteopathies has demonstrated that they are equally effective in elevating the calcium concentration in blood serum occurring at the expense of its increased absorption by the intestine. At the same time certain differences have been discovered in the action of these agents on endocrine regulation. The data obtained provide evidence in favour of the use of vitamin D2 in high doses or of its metabolites not only in renal osteopathies at the stage of chronic renal failure but also in the management of the disorders of phosphorus-calcium metabolism in patients with the nephrotic syndrome in the functional-compensation stage after continuous use of corticosteroids, heparin and diuretics.

Topics: Adolescent; Calcitriol; Calcium; Child; Child, Preschool; Chronic Disease; Chronic Kidney Disease-Mineral and Bone Disorder; Clinical Trials as Topic; Ergocalciferols; Glomerulonephritis; Humans; Hydroxycholecalciferols; Phosphorus