1-hydroxy-3-amino-2-pyrrolidone has been researched along with Inflammation in 5 studies
1-hydroxy-3-amino-2-pyrrolidone: a CNS depressant; structure in first source
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "After intraplantar injection of carrageenin, peripheral inflammation and spinal c-Fos expression are extensive, with the latter being sensitive to both large doses of morphine or N-methyl-D-aspartate receptor antagonism." | 3.69 | Concomitant administration of morphine and an N-methyl-D-aspartate receptor antagonist profoundly reduces inflammatory evoked spinal c-Fos expression. ( Besson, JM; Buritova, J; Chapman, V; Honoré, P, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buritova, J | 4 |
| Le Guen, S | 1 |
| Fournié-Zaluski, MC | 1 |
| Roques, BP | 1 |
| Besson, JM | 4 |
| Hunter, JC | 1 |
| Singh, L | 1 |
| Honoré, P | 3 |
| Chapman, V | 3 |
5 other studies available for 1-hydroxy-3-amino-2-pyrrolidone and Inflammation
| Article | Year |
|---|---|
Antinociceptive effects of RB101(S), a complete inhibitor of enkephalin-catabolizing enzymes, are enhanced by (+)-HA966, a functional NMDA receptor antagonist: a c-Fos study in the rat spinal cord.
Topics: Analgesics; Animals; Carrageenan; Disulfides; Drug Therapy, Combination; Enkephalins; Enzyme Inhibit | 2003 |
Role of excitatory amino acid receptors in the mediation of the nociceptive response to formalin in the rat.
Topics: Analgesics; Animals; Formaldehyde; Inflammation; Male; N-Methylaspartate; Nociceptors; Pain Measurem | 1994 |
Concomitant administration of morphine and an N-methyl-D-aspartate receptor antagonist profoundly reduces inflammatory evoked spinal c-Fos expression.
Topics: Analgesics, Opioid; Animals; Body Temperature; Carrageenan; Gene Expression; Genes, fos; Inflammatio | 1996 |
Interactions between NMDA- and prostaglandin receptor-mediated events in a model of inflammatory nociception.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dose-Response Relationship, Drug; Exc | 1996 |
Physiological contributions of neurokinin 1 receptor activation, and interactions with NMDA receptors, to inflammatory-evoked spinal c-Fos expression.
Topics: Analgesics; Animals; Blood-Brain Barrier; Dose-Response Relationship, Drug; Edema; Excitatory Amino | 1996 |