1-hydroxy-3-amino-2-pyrrolidone and Allodynia studies

1-hydroxy-3-amino-2-pyrrolidone and Allodynia

1-hydroxy-3-amino-2-pyrrolidone: a CNS depressant; structure in first source

Research Excerpts

Excerpt	Relevance	Reference
"Pretreatment with naloxone, an opioid receptor antagonist (1."	1.31	Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors. ( Moriyama, T; Okuda, K; Sakurada, C; Sakurada, S; Sakurada, T; Sugiyama, A; Tan-No, K; Watanabe, C, 2002)
"Thermal hyperalgesia to radiant heat was assessed by using a foot-withdrawal test and NMDA/non-NMDA receptor antagonists were administered intrathecally onto the lumbar spinal cord before and after nerve injury."	1.28	Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy. ( Hayes, RL; Lu, J; Mao, J; Mayer, DJ; Price, DD, 1992)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	1 (33.33)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

1 (33.33)

18.2507

2000's

1 (33.33)

29.6817

2010's

1 (33.33)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Kayser, V	1
Latrémolière, A	1
Hamon, M	1
Bourgoin, S	1
Sakurada, T	1
Watanabe, C	1
Okuda, K	1
Sugiyama, A	1
Moriyama, T	1
Sakurada, C	1
Tan-No, K	1
Sakurada, S	1
Mao, J	1
Price, DD	1
Hayes, RL	1
Lu, J	1
Mayer, DJ	1

Studies

Kayser, V

Latrémolière, A

Hamon, M

Bourgoin, S

Sakurada, T

Watanabe, C

Okuda, K

Sugiyama, A

Moriyama, T

Sakurada, C

Tan-No, K

Sakurada, S

Mao, J

Price, DD

Hayes, RL

Lu, J

Mayer, DJ

Other Studies

3 other studies available for 1-hydroxy-3-amino-2-pyrrolidone and Allodynia

Article	Year
N-methyl-D-aspartate receptor-mediated modulations of the anti-allodynic effects of 5-HT1B/1D receptor stimulation in a rat model of trigeminal neuropathic pain. European journal of pain (London, England), 2011, Volume: 15, Issue:5 Topics: Analgesics, Non-Narcotic; Animals; Cycloserine; Dihydroergotamine; Disease Models, Animal; Drug Syne	2011
Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors. Brain research. Molecular brain research, 2002, Jan-31, Volume: 98, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding, Competitive; Di	2002
Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy. Brain research, 1992, Dec-11, Volume: 598, Issue:1-2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Hot Temperature; Hyperalgesia; I	1992

Article

Year

N-methyl-D-aspartate receptor-mediated modulations of the anti-allodynic effects of 5-HT1B/1D receptor stimulation in a rat model of trigeminal neuropathic pain.

European journal of pain (London, England), 2011, Volume: 15, Issue:5

Topics: Analgesics, Non-Narcotic; Animals; Cycloserine; Dihydroergotamine; Disease Models, Animal; Drug Syne

2011

Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors.

Brain research. Molecular brain research, 2002, Jan-31, Volume: 98, Issue:1-2

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding, Competitive; Di

2002

Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy.

Brain research, 1992, Dec-11, Volume: 598, Issue:1-2

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Hot Temperature; Hyperalgesia; I

1992