Compounds > 1-hydroxy-3-amino-2-pyrrolidone

1-hydroxy-3-amino-2-pyrrolidone and Ache

1-hydroxy-3-amino-2-pyrrolidone has been researched along with Ache in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (50.00)18.2507
2000's4 (40.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Castro Bastos, L; Martins, MA; Melo, NE; Tonussi, CR1
Besson, JM; Buritova, J; Fournié-Zaluski, MC; Le Guen, S; Roques, BP1
Carrigan, KA; Dykstra, LA; Fischer, BD1
Adam, F; Bonnet, F; Le Bars, D1
Millan, MJ; Seguin, L2
Besson, JM; Buritova, J; Chapman, V; Honoré, P1
Christensen, D; Guilbaud, G; Idänpään-Heikkilä, JJ; Kayser, V1
Christensen, D; Guilbaud, G; Kayser, V1
Hayes, RL; Lu, J; Mao, J; Mayer, DJ; Price, DD1

Other Studies

10 other study(ies) available for 1-hydroxy-3-amino-2-pyrrolidone and Ache

ArticleYear
Dependency of nociception facilitation or inhibition after periaqueductal gray matter stimulation on the context.
    Behavioural brain research, 2010, Dec-25, Volume: 214, Issue:2

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; Glycine; Kynurenic Acid; Male; Microinjections; Pain; Pain Measurement; Periaqueductal Gray; Pyrrolidinones; Rats; Rats, Wistar

2010
Antinociceptive effects of RB101(S), a complete inhibitor of enkephalin-catabolizing enzymes, are enhanced by (+)-HA966, a functional NMDA receptor antagonist: a c-Fos study in the rat spinal cord.
    European journal of pain (London, England), 2003, Volume: 7, Issue:3

    Topics: Analgesics; Animals; Carrageenan; Disulfides; Drug Therapy, Combination; Enkephalins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Immunohistochemistry; Inflammation; Male; Naloxone; Narcotic Antagonists; Pain; Phenylalanine; Proto-Oncogene Proteins c-fos; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord

2003
Effects of N-methyl-D-aspartate receptor antagonists on acute morphine-induced and l-methadone-induced antinociception in mice.
    The journal of pain, 2005, Volume: 6, Issue:7

    Topics: Analgesia; Analgesics, Opioid; Animals; Central Nervous System; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyrrolidinones; Reaction Time; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate

2005
Tolerance to morphine analgesia: evidence for stimulus intensity as a key factor and complete reversal by a glycine site-specific NMDA antagonist.
    Neuropharmacology, 2006, Volume: 51, Issue:2

    Topics: Analgesics, Opioid; Animals; Blood Pressure; Drug Tolerance; Electric Stimulation; Heart Rate; Injections, Intravenous; Male; Morphine; Nerve Fibers, Unmyelinated; Pain; Pain Threshold; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex; Stereoisomerism; Sural Nerve

2006
Chemically-diverse ligands at the glycine B site coupled to N-methyl-D-aspartate (NMDA) receptors selectively block the late phase of formalin-induced pain in mice.
    Neuroscience letters, 1994, Aug-29, Volume: 178, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Acetates; Acetic Acid; Animals; Anticonvulsants; Cycloserine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Formaldehyde; Indoles; Ligands; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain; Propionates; Pyrrolidinones; Quinolones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate

1994
(+)-HA 966, a partial agonist at the glycine site coupled to NMDA receptors, blocks formalin-induced pain in mice.
    European journal of pharmacology, 1993, Jul-20, Volume: 238, Issue:2-3

    Topics: Animals; Formaldehyde; Glycine; Hindlimb; Male; Mice; Pain; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate

1993
The contribution of NMDA receptor activation to spinal c-Fos expression in a model of inflammatory pain.
    British journal of pharmacology, 1995, Volume: 116, Issue:1

    Topics: Animals; Carrageenan; Disease Models, Animal; Drug Interactions; Edema; Male; Myelitis; Pain; Proto-Oncogene Proteins c-fos; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Time Factors

1995
The antinociceptive effect of combined systemic administration of morphine and the glycine/NMDA receptor antagonist, (+)-HA966 in a rat model of peripheral neuropathy.
    British journal of pharmacology, 1998, Volume: 125, Issue:8

    Topics: Analgesics, Opioid; Animals; Binding Sites; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Glycine; Hot Temperature; Male; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Nociceptors; Pain; Peripheral Nervous System Diseases; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Mechanical

1998
Complete prevention but stimulus-dependent reversion of morphine tolerance by the glycine/NMDA receptor antagonist (+)-HA966 in neuropathic rats.
    Anesthesiology, 2000, Volume: 92, Issue:3

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Drug Tolerance; Excitatory Amino Acid Antagonists; Injections, Intravenous; Male; Morphine; Pain; Pain Measurement; Peripheral Nervous System Diseases; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate

2000
Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy.
    Brain research, 1992, Dec-11, Volume: 598, Issue:1-2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Pain; Peripheral Nervous System Diseases; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve

1992