1-hexanol has been researched along with Chronic Hepatitis B in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 6 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ayithan, N; Chen, D; Fletcher, SP; Kottilil, S; Poonia, B; Tan, SK; Tang, L; Wallin, JJ | 1 |
| Balsitis, S; Chamberlain, J; Chu, R; Cote, P; Daffis, S; Delaney, WE; Fletcher, SP; Hung, M; Kang, D; Li, B; Li, L; Ma, S; Mackman, R; Menne, S; Mish, M; Pattabiraman, D; Ramakrishnan, D; Ramirez, R; Rowe, W; Santos, R; Spurlock, S; Suresh, M; Voitenleitner, C; Yon, C; Zheng, J | 1 |
| Aktoudianakis, V; Appleby, T; Chamberlain, J; Chin, G; Daffis, S; Delaney, WE; Fletcher, SP; Jin, H; Lee, G; Mackman, RL; Metobo, S; Mish, M; Niu, C; Perry, JK; Pyun, P; Santos, R; Suekawa-Pirrone, K; Villasenor, AG; Yu, H; Zablocki, J; Zheng, J | 1 |
| Ayithan, N; Daffis, S; Fletcher, SP; Gaggar, A; Gane, EJ; German, P; Grant, EP; Joshi, A; Kottilil, S; Lam, T; Lau, AH; Ling, J; Lutz, JD; Mackman, RL; Mathias, A; Poonia, B; Reyes, M; Tan, SK; Woo, J; Wu, P | 1 |
| Amin, OE; Chu, R; Colbeck, EJ; Daffis, S; Davies, J; Fletcher, SP; Frey, C; Javanbakht, H; Khan, S; Lehar, S; Maini, MK; Micolochick Steuer, H; Palazzo, A; Pallett, LJ; Pattabiraman, D; Peiser, L; Ramakrishnan, D; Rosenberg, WMC | 1 |
| Arora, P; Chen, DY; Gaggar, A; Gane, EJ; Kim, HJ; Kim, YJ; Lim, YS; McDonald, C; Nguyen, AH; Roberts, SK; Tan, SK; Visvanathan, K; Wallin, JJ | 1 |
3 trial(s) available for 1-hexanol and Chronic Hepatitis B
| Article | Year |
|---|---|
Safety, pharmacokinetics and pharmacodynamics of selgantolimod, an oral Toll-like receptor 8 agonist: a Phase Ia study in healthy subjects.
Topics: Administration, Oral; Adult; Antiviral Agents; Chemokines; Dose-Response Relationship, Drug; Female; Hepatitis B, Chronic; Hexanols; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-12; Male; Pyrimidines; Toll-Like Receptor 8; Young Adult | 2020 |
Therapeutic Potential of TLR8 Agonist GS-9688 (Selgantolimod) in Chronic Hepatitis B: Remodeling of Antiviral and Regulatory Mediators.
Topics: Adult; Aged; Animals; Antiviral Agents; CD8-Positive T-Lymphocytes; Cohort Studies; Disease Models, Animal; Female; Healthy Volunteers; Hep G2 Cells; Hepatitis B, Chronic; Hexanols; Host-Pathogen Interactions; Humans; Killer Cells, Natural; Leukocytes, Mononuclear; Male; Marmota; Middle Aged; Primary Cell Culture; Pyrimidines; T-Lymphocytes, Regulatory; Toll-Like Receptor 8; Young Adult | 2021 |
Safety, Pharmacokinetics, and Pharmacodynamics of the Oral TLR8 Agonist Selgantolimod in Chronic Hepatitis B.
Topics: Adult; Antiviral Agents; Dizziness; Dose-Response Relationship, Drug; Female; Headache; Hepatitis B, Chronic; Hexanols; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-12 Subunit p40; Male; Middle Aged; Nausea; Pyrimidines; Sustained Virologic Response; Toll-Like Receptor 8 | 2021 |
3 other study(ies) available for 1-hexanol and Chronic Hepatitis B
| Article | Year |
|---|---|
Follicular Helper T (T
Topics: Antiviral Agents; B-Lymphocytes; Case-Control Studies; CD40 Ligand; Cells, Cultured; Enzyme-Linked Immunospot Assay; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hexanols; Host-Pathogen Interactions; Humans; Inducible T-Cell Co-Stimulator Protein; Interleukins; Proto-Oncogene Proteins c-bcl-6; Pyrimidines; Signal Transduction; T Follicular Helper Cells; Toll-Like Receptor 8; Treatment Outcome | 2021 |
Toll-Like Receptor 8 Agonist GS-9688 Induces Sustained Efficacy in the Woodchuck Model of Chronic Hepatitis B.
Topics: Animals; Antiviral Agents; Disease Models, Animal; DNA, Viral; Hepatitis Antibodies; Hepatitis Antigens; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Hexanols; Humans; Marmota; Pyrimidines; Toll-Like Receptor 8; Virus Replication | 2021 |
Discovery of GS-9688 (Selgantolimod) as a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B.
Topics: Administration, Oral; Animals; Antiviral Agents; Crystallography, X-Ray; Dogs; Drug Discovery; Hepatitis B virus; Hepatitis B, Chronic; Hexanols; Humans; Macaca fascicularis; Molecular Structure; Protein Domains; Pyridines; Pyrimidines; Rats; Structure-Activity Relationship; Toll-Like Receptor 8 | 2020 |