Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Thrombopenia

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with Thrombopenia in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199035 (51.47)18.7374
1990's26 (38.24)18.2507
2000's4 (5.88)29.6817
2010's3 (4.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, Z; Jiang, Y; Li, L; Pan, M; Su, EM; Su, X; Sun, P; Sun, W; Wu, H; Yang, J; Yang, X; Zhao, C1
Byrnes, AP; Smith, JS; Tian, J; Xu, Z1
Althaus, K; Greinacher, A; Thiele, T1
Hirasawa, H; Matsuda, K; Nakanishi, K; Oda, S; Shiga, H; Ueno, H1
Fernandes, CJ; O'Donovan, DJ1
Lo, GK; Sigouin, CS; Warkentin, TE1
Greinacher, A1
Alberton, M; Bussolino, F; Caligaris Cappio, F; Camussi, G; Coda, R; Macchiorlatti, E; Roffinello, C; Segoloni, G; Tetta, C1
Deguchi, K; Murashima, S; Shirakawa, S1
Hiller, E; Riess, H1
Goguel, A; Houbouyan, L; Rosenthal, D; Roussi, J; Toulemonde, F1
Brain, H; Carter, CJ; Kelton, JG; Powers, PJ; Sheridan, D; Turpie, AG1
Guay, DR; Richard, A1
Kalmaz, GD; McDonald, TP1
High, JA; Namm, DH; Tadepalli, AS1
Demopoulos, CA; Kapoulas, VM; Tsabikakis, GE1
Crawford, MH; Fitzpatrick, FA; Hanahan, DJ; McManus, LM; O'Rourke, RA; Pinckard, RN1
Demopoulos, CA; Hanahan, DJ; McManus, LM; Pinckard, RN1
Hirayama, K; Matsuzaki, T; Noguchi, K; Ojiri, Y; Sakanashi, M; Shiroma, N1
Aishita, H; Fujitani, B; Katsube, N; Sakaguchi, K1
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Cruz, HN; de Queiroz-Paulo, M; Kaplan, MA; Martins, MA; Silva, PM1
Arreto, CD; Bureau, MF; Imaizumi, A; Vargaftig, BB1
Dodam, JR; Kruse-Elliott, KT; Olson, NC; Whorton, AR1
Kanagawa, H; Kojima, T; Nishihira, J; Suzuki, H; Taguchi, Y1
Barbosa-Filho, JM; Barreto, EO; Cordeiro, RS; de Silva, PM; Diaz, BL; Lima, MC; Martins, MA; Pereira, AP; Serra, MF1
Bailie, MB; Fink, GD; Pearson, JM; Roth, RA1
Battistini, B; Farmer, P; Johnson, RJ; O'Brien, JG; Sirois, P; Zaharia, F1
Barbosa-Filho, JM; Castro-Faria-Neto, HC; Cordeiro, RS; Herbert, JM; Tibiriça, E1
Ashida, Y; Kitao, S; Kobayashi, K; Kyotani, K; Mochizuki, T; Nishizono, K; Scott, MA; Tsuchiya, R; Yamada, T1
Adamson, LM; Podsiadly, BT; Roberts, TK; Smart, YC; Stanger, JD1
Aissa, J; Arnoux, B; Benveniste, J; Nathan, N1
Bernat, A; Gigo, V; Herbert, JM; Lale, A; LaPlace, MC; Le Fur, G; Lespy, L; Maffrand, JP; Savi, P; Valette, G1
Calvo, IF; da Rocha, FA; de Falco, V; Fernandes, AJ; Jancar, S; Sirois, P1
Heuer, H; Kempe, R; Meade, CJ1
Betteridge, KJ; Croy, BA; Johnstone, IB; Rieger, D; Scodras, JM1
Fenton, J; Gudewicz, PW; Kaplan, JE; Moon, DG; van der Zee, H1
Ban, C; Hasegawa, M; Ihara, Y; Inamori, K; Itoh, H; Li, XM; Mori, T; Okagaki, A; Sagawa, N1
Giers, G; Janzarik, H; Kempe, ER; Mueller-Eckhardt, C2
Ando, M; Matsuura, S; Suginami, H1
Halonen, M; Lohman, I1
Farhat, M; Feuerstein, G; Perera, PY; Rabinovici, R; Vogel, SN; Yue, TL1
Isetta, C; Jourdan, J; Kotaiche, M; Lugrin, D; Roul, C1
Jackson, SP; Salem, HH1
Straube, W1
Amiel, ML; Benveniste, J; Duquenne, C; Testart, J1
Braquet, P; Lejeune, V; Mencia-Huerta, JM; Touvay, C; Vilain, B1
Conard, J; Horellou, MH; Lecompte, T; Lecrubier, C; Potevin, F; Samama, M1
Driscoll, EM; Jackson, CV; Kunkel, SL; Lucchesi, BR; Schumacher, WA1
Adamus, WS; Lohmann, HF; Meade, CJ1
Meyers, KM1
Lian, EC1
Kelton, JG; Murphy, WG1
Adnot, S; Braquet, P; Lefort, J; Vargaftig, BB1
Broquet, C; Coeffier, E; Fichelle, J; Godfroid, JJ; Heymans, F; Jouquey, S; Lebbar, M; Michel, E; Redeuilh, C; Steiner, E1
Kanaji, K; Okuma, M; Sensaki, S; Sugiyama, T; Uchino, H; Ushikubi, F1
Adamson, LM; Murdoch, RN; Roberts, TK; Smart, YC; Stanger, JD1
Castro, HC; Cordeiro, RS; Lima, MC; Martins, MA; Neto, F; Silva, PM; Vargaftig, BB1
Angle, MJ; McManus, LM; Pinckard, RN; Showell, HJ1
Lefort, J; Malanchère, E; Pretolani, M; Vargaftig, BB1
Handley, DA; Saunders, RN; Van Valen, RG1
Aoki, H; Kohsaka, M; Nishikawa, M; Okamoto, M; Yoshida, K1
David, R; Pfueller, SL1
Braquet, P; Desquand, S; Lagente, V; Lefort, J; Randon, J; Touvay, C; Vargaftig, BB; Vilain, B1
Issekutz, AC; Szpejda, M1
O'Neill, C1
Morgan, K; Pockros, PJ; Sandler, RM; Schiffman, S; Seifer, DB; Weiss, LM; Wypych, J1

Reviews

8 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Thrombopenia

ArticleYear
[Heparin-induced thrombocytopenia].
    Der Internist, 2010, Volume: 51, Issue:9

    Topics: Acute Disease; Anticoagulants; Autoantibodies; Heparin; Humans; Platelet Activating Factor; Platelet Count; Platelet Factor 4; Thrombocytopenia

2010
Platelet transfusions in infants with necrotizing enterocolitis.
    Current hematology reports, 2006, Volume: 5, Issue:1

    Topics: Enterocolitis, Necrotizing; Humans; Infant, Newborn; Platelet Activating Factor; Platelet Transfusion; Practice Guidelines as Topic; Thrombocytopenia

2006
[Blood platelet aggregation].
    Nihon rinsho. Japanese journal of clinical medicine, 1981, Volume: 39, Issue:12

    Topics: Arachidonic Acids; Calcium; Glycoproteins; Humans; Lysophosphatidylcholines; Membrane Proteins; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Thrombocythemia, Essential; Thrombocytopenia

1981
Biochemical pharmacology of platelet-activating factor (and PAF antagonists) in relation to clinical and experimental thrombocytopenia.
    Biochemical pharmacology, 1991, Mar-01, Volume: 41, Issue:5

    Topics: Animals; Blood Platelets; Humans; Platelet Activating Factor; Platelet Count; Platelet Membrane Glycoproteins; Purpura, Thrombocytopenic; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thrombocytopenia

1991
[Early embryonal signals].
    Zentralblatt fur Gynakologie, 1989, Volume: 111, Issue:10

    Topics: Chaperonin 10; Female; Humans; Immunosuppressive Agents; Peptides; Platelet Activating Factor; Pregnancy; Pregnancy Proteins; Pregnancy Tests; Suppressor Factors, Immunologic; Thrombocytopenia

1989
Pathobiology of animal platelets.
    Advances in veterinary science and comparative medicine, 1985, Volume: 30

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclic AMP; Endotoxins; Epinephrine; Epoprostenol; Glycoproteins; Platelet Activating Factor; Platelet Aggregation; Thrombocytopenia; von Willebrand Factor

1985
Pathogenesis of thrombotic thrombocytopenic purpura.
    Seminars in hematology, 1987, Volume: 24, Issue:2

    Topics: Adult; Blood Platelets; Blood Proteins; Capillaries; Child, Preschool; Endothelium; Epoprostenol; Female; Humans; Microcirculation; Platelet Activating Factor; Platelet Aggregation; Purpura, Thrombotic Thrombocytopenic; Thrombocytopenia; Thrombosis; von Willebrand Factor

1987
Acute thrombocytopenia and thrombosis. Heparin-induced thrombocytopenia and thrombotic thrombocytopenic purpura.
    Annals of the New York Academy of Sciences, 1987, Volume: 509

    Topics: Blood Coagulation Factors; Endothelium, Vascular; Epoprostenol; Heparin; Humans; Platelet Activating Factor; Purpura, Thrombotic Thrombocytopenic; Thrombocytopenia; von Willebrand Factor

1987

Other Studies

60 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Thrombopenia

ArticleYear
Lipoxin A4 and platelet activating factor are involved in E. coli or LPS-induced lung inflammation in CFTR-deficient mice.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Bronchoalveolar Lavage; Chemokine CXCL2; Cystic Fibrosis Transmembrane Conductance Regulator; Escherichia coli; Lipopolysaccharides; Lipoxins; Mice, Inbred CFTR; Mutation; P-Selectin; Platelet Activating Factor; Platelet Count; Pneumonia; Thrombocytopenia

2014
Induction of shock after intravenous injection of adenovirus vectors: a critical role for platelet-activating factor.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2010, Volume: 18, Issue:3

    Topics: Adenoviridae; Animals; Cytokines; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Lipids; Mononuclear Phagocyte System; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock; Signal Transduction; Thrombocytopenia

2010
Coagulation/fibrinolysis abnormality and vascular endothelial damage in the pathogenesis of thrombocytopenic multiple organ failure.
    Critical care medicine, 2002, Volume: 30, Issue:10

    Topics: Adult; Aged; Blood Coagulation; Endothelium, Vascular; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Humans; Interleukin-6; Leukocyte Elastase; Male; Middle Aged; Multiple Organ Failure; Platelet Activating Factor; Platelet Count; Retrospective Studies; Sepsis; Thrombocytopenia; Thrombomodulin

2002
What is the potential for overdiagnosis of heparin-induced thrombocytopenia?
    American journal of hematology, 2007, Volume: 82, Issue:12

    Topics: Aged; Aged, 80 and over; Autoantibodies; Diagnosis, Differential; Female; Heparin; Humans; Male; Middle Aged; Platelet Activating Factor; Survival Analysis; Thrombocytopenia; Thrombosis

2007
Too many hits in HIT?
    American journal of hematology, 2007, Volume: 82, Issue:12

    Topics: Autoantibodies; Heparin; Humans; Platelet Activating Factor; Thrombocytopenia

2007
Effect of prostacyclin (PGI2) on immune-complex-induced neutropenia.
    Immunology, 1983, Volume: 48, Issue:4

    Topics: Agranulocytosis; Animals; Antigen-Antibody Complex; Cell Aggregation; Epoprostenol; Neutropenia; Neutrophils; Platelet Activating Factor; Prostaglandins; Rabbits; Thrombocytopenia

1983
Heparin and thrombocytopenia.
    Annals of internal medicine, 1984, Volume: 101, Issue:6

    Topics: Blood Coagulation Factors; Heparin; Humans; Platelet Activating Factor; Platelet Aggregation; Thrombocytopenia

1984
[Success of treatment with a low-molecular-weight heparin fraction in a case of pulmonary embolism complicated by heparin-induced thrombopenia].
    Nouvelle revue francaise d'hematologie, 1983, Volume: 25, Issue:4

    Topics: Adult; Blood Coagulation Factors; Female; Heparin; Humans; Molecular Weight; Platelet Activating Factor; Platelet Aggregation; Pulmonary Embolism; Thrombocytopenia

1983
Clinical usefulness of testing for a heparin-dependent platelet-aggregating factor in patients with suspected heparin-associated thrombocytopenia.
    The Journal of laboratory and clinical medicine, 1984, Volume: 103, Issue:4

    Topics: Adult; Aged; Blood Coagulation Factors; Female; Heparin; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Thrombocytopenia

1984
Heparin-induced thrombocytopenia--association with a platelet aggregating factor and cross-sensitivity to bovine and porcine heparin.
    Drug intelligence & clinical pharmacy, 1984, Volume: 18, Issue:5

    Topics: Adult; Animals; Blood Coagulation Factors; Blood Platelets; Cattle; Heparin; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Swine; Thrombocytopenia

1984
Effects of thrombopoietin on the number and diameter of marrow megakaryocytes of mice.
    Experimental hematology, 1983, Volume: 11, Issue:2

    Topics: Animals; Blood Platelets; Bone Marrow Cells; Cell Count; Glycoproteins; Immune Sera; Male; Megakaryocytes; Mice; Mice, Inbred C3H; Platelet Activating Factor; Platelet Count; Rabbits; Thrombocytopenia; Thrombopoietin

1983
Species specificity of the platelet responses to 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine.
    Thrombosis research, 1982, Feb-15, Volume: 25, Issue:4

    Topics: Anesthesia; Animals; Blood Coagulation; Blood Platelets; Calcium Chloride; Cats; Dogs; Ether; Guinea Pigs; Heart Rate; Horses; Humans; Hypotension; Lysophosphatidylcholines; Male; Mice; Mice, Inbred Strains; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Serotonin; Species Specificity; Thrombocytopenia

1982
Intravascular pathobiology of acetyl glyceryl ether phosphorylcholine (AGEPC), a synthetic platelet-activating factor (PAF). I. Intravenous infusion in guinea pigs.
    Immunology letters, 1981, Volume: 3, Issue:3

    Topics: Anaphylaxis; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; Infusions, Parenteral; Leukocyte Count; Leukopenia; Lysophosphatidylcholines; Male; Papio; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Rabbits; Thrombocytopenia

1981
Acetyl glyceryl ether phosphorylcholine. Intravascular alterations following intravenous infusion into the baboon.
    Laboratory investigation; a journal of technical methods and pathology, 1981, Volume: 45, Issue:4

    Topics: Animals; Blood Cell Count; Blood Coagulation Factors; Blood Proteins; Hematocrit; Infusions, Parenteral; Lysophosphatidylcholines; Neutropenia; Papio; Platelet Activating Factor; Platelet Factor 4; Species Specificity; Thrombocytopenia; Thromboxane B2; Thromboxanes

1981
Pathobiology of the intravenous infusion of acetyl glyceryl ether phosphorylcholine (AGEPC), a synthetic platelet-activating factor (PAF), in the rabbit.
    Journal of immunology (Baltimore, Md. : 1950), 1980, Volume: 124, Issue:6

    Topics: Animals; Basophils; Blood Platelets; Dose-Response Relationship, Drug; Female; Infusions, Parenteral; Leukocyte Count; Lysophosphatidylcholines; Male; Neutropenia; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Platelet Factor 4; Rabbits; Thrombocytopenia

1980
Haemodynamic and haematologic effects of Acanthaster planci venom in dogs.
    Toxicon : official journal of the International Society on Toxinology, 1994, Volume: 32, Issue:10

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Cells; Blood Pressure; Cardiac Output; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypotension; Indomethacin; Injections, Intravenous; Leukopenia; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Starfish; Tachyphylaxis; Thrombocytopenia; Vascular Resistance; Venoms

1994
Anti-platelet and anti-thrombotic effects of OP-41483.alpha-CD, a prostacyclin analogue, in experimental animals.
    Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 49, Issue:4

    Topics: Adenosine Diphosphate; alpha-Cyclodextrins; Animals; Arachidonic Acid; Blood Coagulation Factors; Blood Platelets; Blood Pressure; Collagen; Cyclodextrins; Dogs; Epoprostenol; Female; Fibrinolytic Agents; Humans; Macaca; Male; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Rabbits; Rats; Rats, Wistar; Species Specificity; Thrombocytopenia

1993
Pharmacological profile of epiyangambin: a furofuran lignan with PAF antagonist activity.
    Journal of lipid mediators, 1993, Volume: 7, Issue:1

    Topics: Animals; Furans; Lignans; Lignin; Male; Molecular Structure; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Wistar; Thrombocytopenia

1993
Pharmacological differentiation by pertussis toxin of the in vivo acute responses to fMLP and PAF in guinea-pig lungs.
    British journal of pharmacology, 1993, Volume: 108, Issue:2

    Topics: Acetylcholine; Animals; Blood Platelets; Blood Volume; Bronchoconstriction; Capillary Permeability; Female; Guinea Pigs; Leukocytes; Leukopenia; Lung; Male; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Thrombocytopenia; Virulence Factors, Bordetella

1993
Pertussis toxin attenuates platelet-activating factor-induced pulmonary hemodynamic alterations in pigs.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 1

    Topics: Animals; Blood Platelets; Calcimycin; GTP-Binding Proteins; Hemodynamics; Indomethacin; Injections, Intravenous; Lung; Pertussis Toxin; Phosphorylation; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Sodium Chloride; Swine; Thrombocytopenia; Thromboxane B2; Time Factors; Vasoconstriction; Virulence Factors, Bordetella

1993
Evidence for the production of platelet-activating factor by murine embryos and its putative role in the maternal physiology.
    Biochemistry and molecular biology international, 1995, Volume: 37, Issue:4

    Topics: Animals; Culture Techniques; Embryo, Mammalian; Female; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Pregnancy; Pregnancy Complications, Hematologic; Rabbits; Thrombocytopenia

1995
Clinical studies of IL-11, new platelet growth factor, presented.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:2

    Topics: Animals; Breast Neoplasms; Clinical Trials as Topic; Hematopoiesis; Humans; Interleukin-11; Neoplasms; Platelet Activating Factor; Recombinant Proteins; Sepsis; Thrombocytopenia

1997
Anti-allergic properties of the natural PAF antagonist yangambin.
    Planta medica, 1997, Volume: 63, Issue:3

    Topics: Animals; Anti-Allergic Agents; Eosinophils; Female; Furans; Leukocytosis; Lignans; Male; Neutrophils; Plant Extracts; Platelet Activating Factor; Pleurisy; Rats; Rats, Wistar; Thrombocytopenia

1997
Neither platelet activating factor nor leukotrienes are critical mediators of liver injury after lipopolysaccharide administration.
    Toxicology, 1997, Sep-05, Volume: 121, Issue:3

    Topics: Administration, Oral; Alanine Transaminase; Animals; Azepines; Blood Platelets; Chemical and Drug Induced Liver Injury; Female; Fibrinogen; Hydroxyurea; Injections, Intraperitoneal; Injections, Intravenous; Leukotrienes; Lipopolysaccharides; Lipoxygenase Inhibitors; Liver; Liver Diseases; Necrosis; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombocytopenia; Triazoles

1997
Effects of tranexamic acid and aprotinin on PAF-induced vascular permeability in normal, thrombocytopenic or neutropenic rats.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46 Suppl 2

    Topics: Animals; Antifibrinolytic Agents; Aprotinin; Bronchi; Capillary Permeability; Male; Neutropenia; Platelet Activating Factor; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Thrombocytopenia; Trachea; Tranexamic Acid; Trypsin Inhibitors

1997
Pharmacological evidence for the putative existence of two different subtypes of PAF receptors on platelets and leukocytes; studies with yangambin.
    Journal of lipid mediators and cell signalling, 1997, Volume: 17, Issue:1

    Topics: Animals; Blood Platelets; Furans; Guinea Pigs; Humans; Interleukin-1; Interleukin-6; Kinetics; Leukocytes; Leukopenia; Lignans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Burst; Thiazoles; Thrombocytopenia; Tumor Necrosis Factor-alpha

1997
Role of platelet activating factor in development of thrombocytopenia and neutropenia in dogs with endotoxemia.
    American journal of veterinary research, 1999, Volume: 60, Issue:2

    Topics: Animals; Blood Coagulation Tests; Dog Diseases; Dogs; Endotoxemia; Female; Isoquinolines; Leukocyte Count; Lipopolysaccharides; Male; Neutropenia; Pilot Projects; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Count; Pyridinium Compounds; Radioimmunoassay; Tetrahydroisoquinolines; Thrombocytopenia

1999
Prefertilization treatment of mice with platelet activating factor affects pregnancy.
    Molecular reproduction and development, 1992, Volume: 32, Issue:4

    Topics: Animals; Embryo Implantation; Embryonic and Fetal Development; Female; Fertilization; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Platelet Activating Factor; Pregnancy; Pregnancy, Animal; Thrombocytopenia

1992
Role of paf-acether in protamine-induced thrombocytopenia in rabbits.
    European journal of anaesthesiology, 1992, Volume: 9, Issue:4

    Topics: Animals; Heparin Antagonists; Platelet Activating Factor; Protamines; Rabbits; Thrombocytopenia

1992
Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:1

    Topics: Animals; Azepines; Blood Platelets; Bronchoconstriction; Guinea Pigs; Humans; Injections, Intravenous; Leukopenia; Male; Mice; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thrombocytopenia; Triazoles

1991
Mechanisms of thrombocytopenia in the acute phase of antigen-induced arthritis in rabbits.
    Prostaglandins, 1991, Volume: 42, Issue:6

    Topics: Animals; Arthritis, Experimental; Diterpenes; Econazole; Female; Ginkgolides; Indoles; Indomethacin; Lactones; Male; Platelet Activating Factor; Rabbits; Synovial Fluid; Thrombocytopenia; Thromboxane A2; Thromboxane B2

1991
Failure to detect platelet-activating factor using the splenectomized mouse bioassay.
    Journal of reproduction and fertility, 1991, Volume: 92, Issue:2

    Topics: Adenosine Diphosphate; Animals; Biological Assay; Blood Platelets; Cattle; Horses; Mice; Mice, Inbred Strains; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Splenectomy; Thrombin; Thrombocytopenia

1991
Thrombin-induced leukopenia and thrombocytopenia are attenuated by PAF antagonist WEB 2086.
    The Journal of laboratory and clinical medicine, 1991, Volume: 117, Issue:4

    Topics: Animals; Azepines; Carbon Dioxide; Cell Adhesion; Leukocyte Count; Leukopenia; Platelet Activating Factor; Sheep; Thrombin; Thrombocytopenia; Thromboxane B2; Triazoles

1991
The involvement of platelet-activating factor in thrombocytopenia and follicular rupture during gonadotropin-induced superovulation in immature rats.
    Endocrinology, 1991, Volume: 129, Issue:6

    Topics: Animals; Azepines; Chorionic Gonadotropin; Female; Gonadotropins, Equine; Indomethacin; Ovulation; Ovulation Induction; Platelet Activating Factor; Platelet Activation; Platelet Count; Rats; Rats, Inbred Strains; Superovulation; Thrombocytopenia; Triazoles; Vena Cava, Inferior

1991
PAF-acether-antagonist WEB 2086 for treatment of chronic idiopathic thrombocytopenia.
    Lancet (London, England), 1990, Jul-21, Volume: 336, Issue:8708

    Topics: Azepines; Chronic Disease; Drug Evaluation; Humans; Platelet Activating Factor; Thrombocytopenia; Triazoles

1990
Pregnancy suppression by a structurally related antagonist for platelet activating factor, CV-6209, in mice.
    Asia-Oceania journal of obstetrics and gynaecology, 1990, Volume: 16, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Embryo Implantation; Embryonic and Fetal Development; Embryonic Development; Female; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Count; Pregnancy; Pregnancy, Animal; Pyridinium Compounds; Thrombocytopenia; Time Factors

1990
Effects of the PAF antagonist WEB 2086 on PAF-induced physiologic alterations and on IgE anaphylaxis in the rabbit.
    The American review of respiratory disease, 1990, Volume: 142, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Bronchial Spasm; Hypotension; Immunoglobulin E; Leukopenia; Lung; Platelet Activating Factor; Rabbits; Thrombocytopenia; Triazoles

1990
Failure of the platelet-activating-factor antagonist WEB 2086 BS for treatment of chronic autoimmune thrombocytopenia.
    Blut, 1990, Volume: 61, Issue:1

    Topics: Adult; Aged; Autoimmune Diseases; Azepines; Chronic Disease; Drug Evaluation; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Prospective Studies; Thrombocytopenia; Triazoles

1990
Protective effect of BN 50739, a new platelet-activating factor antagonist, in endotoxin-treated rabbits.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:3

    Topics: Animals; Azepines; Blood Cell Count; Endotoxins; Leukopenia; Male; Platelet Activating Factor; Rabbits; Thrombocytopenia; Thromboxane B2; Triazoles

1990
[Thrombocytopenia induced by heparin and cardiac surgery with extracorporeal circulation].
    Annales francaises d'anesthesie et de reanimation, 1990, Volume: 9, Issue:4

    Topics: Blood Coagulation Factors; Cardiac Surgical Procedures; Extracorporeal Circulation; Female; Heparin; Humans; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Postoperative Period; Thrombocytopenia; Vitamin K

1990
Platelet aggregating activity in the plasma of patients with established thrombosis.
    Australian and New Zealand journal of medicine, 1989, Volume: 19, Issue:2

    Topics: Adult; Aged; Aspirin; Benzamidines; Blood Coagulation Factors; Edetic Acid; Humans; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Thrombocytopenia; Thrombosis; Time Factors

1989
Platelet aggregating activity in human embryo culture media free of PAF-acether.
    Human reproduction (Oxford, England), 1989, Volume: 4, Issue:3

    Topics: Animals; Biological Assay; Cells, Cultured; Culture Media; Embryo, Mammalian; Humans; Mice; Platelet Activating Factor; Platelet Aggregation; Thrombocytopenia

1989
Effect of cyclosporin A and the platelet-activating factor (PAF) antagonist, BN 52021, on PAF- and antigen- induced bronchoconstriction in the guinea-pig.
    Biochemical and biophysical research communications, 1989, Aug-30, Volume: 163, Issue:1

    Topics: Animals; Antigens; Bronchial Provocation Tests; Bronchial Spasm; Cyclosporins; Diterpenes; Ginkgolides; Guinea Pigs; Immunization, Passive; In Vitro Techniques; Lactones; Leukopenia; Male; Platelet Activating Factor; Thrombocytopenia

1989
[Platelet aggregation tests in 26 cases of heparin-induced thrombopenia. Methodological, diagnostic problems and therapeutic aspects].
    Journal des maladies vasculaires, 1987, Volume: 12 Suppl B

    Topics: Adult; Aged; Blood Coagulation Factors; Female; Heparin; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Thrombocytopenia

1987
Platelet-activating factor and the release of a platelet-derived coronary artery vasodilator substance in the canine.
    Circulation research, 1986, Volume: 58, Issue:2

    Topics: Animals; Aspirin; Coronary Circulation; Coronary Vessels; Diphenhydramine; Dogs; Histamine H1 Antagonists; Male; Methacholine Compounds; Methysergide; Nitroglycerin; Platelet Activating Factor; Thrombocytopenia; Vasodilation

1986
Idiopathic thrombocytopenia treated with Paf-acether antagonist WEB 2086.
    Lancet (London, England), 1988, Nov-12, Volume: 2, Issue:8620

    Topics: Administration, Oral; Azepines; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Count; Thrombocytopenia; Triazines; Triazoles

1988
Interference of the PAF-acether antagonist BN 52021 with endotoxin-induced hypotension in the guinea-pig.
    Prostaglandins, 1986, Volume: 32, Issue:6

    Topics: Animals; Diterpenes; Female; Ginkgolides; Guinea Pigs; Hypotension; Lactones; Male; Plant Extracts; Platelet Activating Factor; Shock, Septic; Thrombocytopenia

1986
Structure-activity relationship in PAF-acether. 3. Hydrophobic contribution to agonistic activity.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:5

    Topics: Animals; Blood Pressure; Bronchi; Chemical Phenomena; Chemistry; Constriction, Pathologic; Guinea Pigs; Male; Molecular Conformation; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thrombocytopenia

1987
A novel platelet aggregating factor found in a patient with defective collagen-induced platelet aggregation and autoimmune thrombocytopenia.
    Blood, 1987, Volume: 69, Issue:6

    Topics: Autoimmune Diseases; Blood Coagulation Factors; Blood Platelet Disorders; Collagen; Female; Humans; Immunoglobulin G; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Purpura, Thrombocytopenic; Thrombocytopenia; Thromboxane B2

1987
Mechanistic studies of early pregnancy associated thrombocytopenia (EPAT) in the mouse.
    American journal of reproductive immunology and microbiology : AJRIM, 1987, Volume: 13, Issue:4

    Topics: Animals; Blood Platelets; Embryonic Development; Female; Mice; Platelet Activating Factor; Platelet Count; Pregnancy; Pregnancy Complications, Hematologic; Thrombocytopenia

1987
Interactions between local inflammatory and systemic haematological effects of PAF-acether in the rat.
    European journal of pharmacology, 1987, Apr-29, Volume: 136, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Edema; Indomethacin; Inflammation; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombocytopenia

1987
Ontogeny of the responsiveness to intravenous platelet-activating factor.
    Laboratory investigation; a journal of technical methods and pathology, 1987, Volume: 57, Issue:3

    Topics: Aging; Anaphylaxis; Animals; Animals, Newborn; Female; Leukopenia; Lung; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Factor 4; Rabbits; Thrombocytopenia; Thromboxane B2

1987
Interference by the novel PAF-acether antagonist WEB 2086 with the bronchopulmonary responses to PAF-acether and to active and passive anaphylactic shock in guinea-pigs.
    European journal of pharmacology, 1987, Aug-21, Volume: 140, Issue:3

    Topics: Anaphylaxis; Animals; Azepines; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indicators and Reagents; Leukopenia; Male; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Radioimmunoassay; Respiratory System; Spectrometry, Fluorescence; Thrombocytopenia; Thromboxane B2; Triazines; Triazoles

1987
Vascular responses of platelet-activating factor in the Cebus apella primate and inhibitory profiles of antagonists SRI 63-072 and SRI 63-119.
    Immunopharmacology, 1986, Volume: 11, Issue:3

    Topics: Animals; Cebus; Indomethacin; Lung; Macaca mulatta; Male; Papio; Platelet Activating Factor; Platelet Aggregation; Thiazoles; Thrombocytopenia; Thromboxane B2

1986
Platelet activating factor (PAF) involvement in endotoxin-induced thrombocytopenia in rabbits: studies with FR-900452, a specific inhibitor of PAF.
    Thrombosis research, 1986, Jun-01, Volume: 42, Issue:5

    Topics: Animals; Cell Count; Depression, Chemical; Drug Interactions; Endotoxins; Indoles; Injections, Intravenous; Leukopenia; Male; Piperazines; Platelet Activating Factor; Rabbits; Thrombocytopenia; Time Factors

1986
Different platelet specificities of heparin-dependent platelet aggregating factors in heparin-associated immune thrombocytopenia.
    British journal of haematology, 1986, Volume: 64, Issue:1

    Topics: Antibody Specificity; Blood Coagulation Factors; Blood Platelets; Epinephrine; Heparin; Humans; Platelet Activating Factor; Platelet Aggregation; Thrombocytopenia

1986
Pharmacological control of the in vivo passive anaphylactic shock by the PAF-acether antagonist compound BN 52021.
    Pharmacological research communications, 1986, Volume: 18 Suppl

    Topics: Anaphylaxis; Animals; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; Lactones; Plant Extracts; Platelet Activating Factor; Propranolol; Pyrilamine; Thrombocytopenia

1986
Evidence that platelet activating factor may mediate some acute inflammatory responses. Studies with the platelet-activating factor antagonist, CV3988.
    Laboratory investigation; a journal of technical methods and pathology, 1986, Volume: 54, Issue:3

    Topics: Acute Disease; Animals; Blood Platelets; Capillary Permeability; Cell Movement; Inflammation; Leukocytes; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phospholipid Ethers; Platelet Activating Factor; Rabbits; Regional Blood Flow; Serum Albumin; Skin; Thiazoles; Thrombocytopenia

1986
Examination of the causes of early pregnancy-associated thrombocytopenia in mice.
    Journal of reproduction and fertility, 1985, Volume: 73, Issue:2

    Topics: Animals; Bleeding Time; Blood Coagulation; Culture Media; Embryonic Development; Female; Genotype; Mice; Mice, Inbred Strains; Parthenogenesis; Platelet Activating Factor; Platelet Count; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy, Animal; Pseudopregnancy; Splenectomy; Thrombocytopenia

1985
Heparin-induced thrombocytopenia and thrombosis: detection and specificity of a platelet-aggregating IgG.
    American journal of clinical pathology, 1985, Volume: 83, Issue:6

    Topics: Blood Coagulation Factors; Chromatography, Affinity; Female; Heparin; Humans; Immunoglobulin G; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Sepharose; Thrombocytopenia; Thrombosis

1985