Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Pancreatitis

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with Pancreatitis in 93 studies

Research

Studies (93)

TimeframeStudies, this research(%)All Research%
pre-19904 (4.30)18.7374
1990's54 (58.06)18.2507
2000's33 (35.48)29.6817
2010's2 (2.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bloechle, C; Izbicki, JR; Kaifi, J; Kluth, D; Mann, O; Schneider, C; Strate, T; Tiefenbacher, WJ; Yekebas, E1
Cai, Y; Chen, L; Jiang, X; Tian, H; Wu, C; Xu, R; Ye, Q; Yuan, W; Zhang, X1
Mayerle, J1
Fangjie, Z; Guanghua, F; Jie, N; Meili, M; Xinmei, H; Xiping, Z; Yan, P1
Di, Y; Tong, CQ; Xia, SH1
Akbarshahi, H; Andersson, R; Rosendahl, AH; Westergren-Thorsson, G1
Abu-Zidan, FM; Windsor, JA1
Kingsnorth, AN; Makhija, R1
Chen, JW; Li, PY; Zhao, H; Zhou, XF; Zhou, YK1
Andersson, R; Börjesson, A; Haraldsen, P; Lasson, A; Olanders, K; Sun, ZW1
Chmiel, B1
Huseyinov, A; Ozutemiz, O; Saruc, M; Turkel, N; Tuzcuoglu, I; Yuce, G; Yuceyar, H1
Shabanov, VV1
Kraft, M; Lerch, MM; Mayerle, J; Meister, T; Simon, P1
Takeda, K1
Kuroda, Y; Takase, K; Ueda, T1
Andersson, E; Andersson, R; Börjesson, A; Leveau, P; Sun, Z; Wang, X1
Granger, J; Remick, D1
Clavien, PA; Heinrich, S; Rousson, V; Schäfer, M1
Liu, LR; Xia, SH1
Jancar, S; Machado, MC; Molan, NA; Shio, MT; Souza, LJ1
Di, Y; Hu, CX; Xia, GD; Xia, SH; Zhao, ZL1
Wang, L; Zhang, XP; Zhou, YF1
Bang, UC; Bendtsen, F; Nojgaard, C; Semb, S1
Formela, LJ; Galloway, SW; Kingsnorth, AN1
Alonso, R; Arévalo, M; Calvo, JJ; García, LJ; López-Novoa, JM; Montero, A; Rodríguez-Nodal, F; Sánchez-Vicente, C1
Hirano, T; Imamura, T; Kyogoku, T; Manabe, T; Ohshio, G; Yamamoto, M; Yoshitomi, S; Yotsumoto, F1
Abdo, EE; Bonizzia, A; Coelho, AM; Jancar, S; Kwasniewski, FH; Machado, MC; Sampietre, SN1
Chyczewski, L; Dabrowski, A; Gabryelewicz, A2
Albert, DH; Summers, JB1
Ji, Z; Li, S; Wang, B2
Battaglia, E; Camussi, G; De Giuli, P; De Martino, A; Dughera, L; Emanuelli, G; Gaia, E; Gubetta, L; Lupia, E; Montrucchio, G1
Formela, LJ; Kingsnorth, AN; Whittaker, M; Wood, LM1
Jewell, DP; Travis, SP1
Levine, BA; Olson, MS; Zhou, W2
Ihse, I; Kald, A; Kald, B; Tagesson, C1
Han, Q; Miller, JE; Olson, MS; Shen, F; Zhou, W1
Galloway, SW; Kingsnorth, AN1
Braquet, P; Gukovskaya, A; Gukovsky, S; Pandol, SJ; Poucell-Hatton, S; Reavey, P; Sandoval, D; Sisk, A1
Gabryelewicz, A1
Kingsnorth, AN1
Closa, D; Gelpí, E; Hotter, G; Pi, F; Prats, N; Roselló-Catafau, J1
Baxter, JN; Curran, FJ; Imrie, CW; McKay, C; Sharples, CE; Young, CA1
Curtis, LD1
Carter, G; Denham, D; Denham, W; Fink, G; Norman, J; Ward, K; Yang, J1
Manji, M; Neoptolemos, JP; Wilson, PG1
Andersson, R; Deng, X; Ihse, I; Soltesz, V; Sun, Z; Wang, X1
Abu-Zidan, FM1
Bhagat, L; Bhatia, M; Frossard, JL; Hofbauer, B; Lee, HS; Saluja, AK; Steer, ML1
Andersson, R; Börjesson, A; Sun, Z; Wang, X1
Johnson, CD1
Aldman, M; Andersson, R; Börjesson, A; Deng, X; Haraldsen, P; Leveau, P; Sun, Z; Wang, X1
Akizuki, E; Ishihara, K; Liang, J; Matsuda, T; Matsumura, F; Ogawa, M; Ohshiro, H; Okabe, K; Yamada, S; Yamaguchi, Y1
Markert, R; Modzelewski, B1
Ekiz, F; Fincan, K; Haklar, G; Köksoy, F; Soybir, G; Yalçin, O; Yüksel, M1
Bassi, C; Bradley, E; Dervenis, C; Imrie, CW; Johnson, CD; McMahon, MJ; Modlin, I1
Denham, W; Norman, J1
Blackstone, MO1
Imrie, CW; McKay, CJ2
Kuśnierz, B; Naskalski, JW1
Closa, D; Folch, E; Gelpí, E; Panés, J; Piqué, JM; Prats, N; Roselló-Catafau, J; Salas, A1
Goshima, M; Hori, Y; Kuroda, Y; Takase, K; Takeyama, Y; Ueda, T1
Chyczewski, L; Dlugosz, JW; Gabryelewicz, A; Siemiatkowski, A; Wereszczynska-Siemiatkowska, U1
Brady, M; Christmas, S; Neoptolemos, J; Slavin, J; Sutton, R1
Curtis, LD; Imrie, CW; Johnson, CD; Kingsnorth, AN; Larvin, M; Leeder, PC; McKay, C; McMahon, MJ; Neoptolemos, JP; Skaife, P; Toh, SK; Wilson, P1
Ashley, SW; Chandler, CF; Gloor, B; Kau, AW; Lane, JS; McFadden, DW; Reber, HA; Todd, KE1
Steer, ML1
Bhatia, M; Neoptolemos, JP; Slavin, J1
Geissler, F; Hauss, J; Ludwig, S; Tannapfel, A; Uhlmann, D; Witzigmann, H1
Li, J; Li, N; Tu, W; Zhu, W1
McKay, CJ1
Chen, YD; Zhou, ZG1
Banaś, M; Dembiński, A; Konturek, SJ; Stachura, J; Tomaszewska, R; Warzecha, Z1
Hirano, T; Manabe, T1
Dembinski, A; Gustaw, P; Jaworek, J; Konturek, PJ; Konturek, SJ; Stachura, J; Tomaszewska, R; Warzecha, Z1
Iwahisa, Y; Okamoto, H; Terasawa, M1
Creutzfeldt, W; Fayyazzi, A; Leonhardt, U; Seidensticker, F; Söling, HD; Stöckmann, F1
Ais, JG; Gómez-Garre, M; López-Farre, A; López-Novoa, JM; Novo, C; Romeo, JM1
Levine, BA; McCollum, MO; Olson, MS; Zhou, W1
Chao, W; Levine, BA; Olson, MS; Zhou, WG1
Ais, G; Braquet, P; Gomez-Garre, DN; López-Farre, A; López-Novoa, JM; Novo, C; Romeo, JM1
Baskin, DG; Beck, JC; Braquet, P; Glidden, D; Goodner, CJ; Lernmark, A; Wilson, C; Wilson, D1
Arita, Y; Furukawa, M; Kimura, T; Nawata, H; Sumii, T; Takano, S; Yamaguchi, H1
Polonskiĭ, VM1
Mikhailidis, DP; Peplow, PV1
Corvetti, G; Dughera, L; Emanuelli, G; Gaia, E; Gubetta, L; Montrucchio, G1
Bielawiec, M; Bodzenta-Lukaszyk, A; Gabryelewicz, A; Lukaszyk, A1
Clarke, GM; Leonelli, FM; Leong, LL; Strophair, JA; Sturm, MJ; Taylor, RR1
Braquet, P; De Giaccobi, G; Jancar, S; Mariano, M; Mencia-Huerta, JM; Sirois, P1

Reviews

30 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Pancreatitis

ArticleYear
Acute lung injury in acute pancreatitis--awaiting the big leap.
    Respiratory medicine, 2012, Volume: 106, Issue:9

    Topics: Acute Disease; Acute Lung Injury; Chemokines; Cytokines; Humans; Kupffer Cells; Macrophages; Mast Cells; Matrix Metalloproteinases; Neutrophils; NF-kappa B; Pancreatitis; Platelet Activating Factor; Poly(ADP-ribose) Polymerases; Substance P

2012
Lexipafant and acute pancreatitis: a critical appraisal of the clinical trials.
    The European journal of surgery = Acta chirurgica, 2002, Volume: 168, Issue:4

    Topics: Acute Disease; Anti-Inflammatory Agents; Clinical Trials as Topic; Humans; Imidazoles; Leucine; Pancreatitis; Platelet Activating Factor

2002
Cytokine storm in acute pancreatitis.
    Journal of hepato-biliary-pancreatic surgery, 2002, Volume: 9, Issue:4

    Topics: Acute Disease; Animals; Antibody Formation; Apoptosis; Disease Progression; Humans; Immunity, Cellular; Interleukin-1; Interleukin-10; Interleukin-6; Interleukins; Pancreatitis; Platelet Activating Factor; Systemic Inflammatory Response Syndrome; Tumor Necrosis Factor-alpha

2002
[Conservative treatment of acute pancreatitis].
    Medizinische Klinik (Munich, Germany : 1983), 2003, Dec-15, Volume: 98, Issue:12

    Topics: Acute Disease; Adjuvants, Immunologic; Analgesics; Animals; Anti-Bacterial Agents; APACHE; C-Reactive Protein; Cholangiography; Cholangiopancreatography, Endoscopic Retrograde; Clinical Trials as Topic; Disease Models, Animal; Double-Blind Method; Enteral Nutrition; Humans; Imidazoles; Leucine; Multicenter Studies as Topic; Multiple Organ Failure; Pancreatitis; Pancreatitis, Acute Necrotizing; Placebos; Platelet Activating Factor; Prognosis; Protease Inhibitors; Randomized Controlled Trials as Topic; Retrospective Studies; Tomography, X-Ray Computed

2003
[Role of increase in permeability and circulatory failure in the development of organ dysfunction in severe acute pancreatitis].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62, Issue:11

    Topics: Acute Disease; Animals; Bradykinin; Capillary Permeability; Formycins; Histamine; Humans; Interleukin-1; Microcirculation; Neutrophil Infiltration; Pancreatitis; Platelet Activating Factor; Ribonucleotides; Severity of Illness Index; Shock; Thrombin; Thrombophilia; Tumor Necrosis Factor-alpha

2004
[New aspects of pharmaco-therapy for acute pancreatitis].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62, Issue:11

    Topics: Acute Disease; Animals; Blood Proteins; Clinical Trials as Topic; Drug Design; Humans; Imidazoles; Leucine; Octreotide; Pancreatitis; Platelet Activating Factor; Proglumide; Pyridines; Receptor, Cholecystokinin A; Somatostatin

2004
Acute pancreatitis: models, markers, and mediators.
    Shock (Augusta, Ga.), 2005, Volume: 24 Suppl 1

    Topics: Acute Disease; Adult; Animals; Biomarkers; Cytokines; Disease Models, Animal; Humans; Inflammation; Pancreatitis; Platelet Activating Factor

2005
Evidence-based treatment of acute pancreatitis: a look at established paradigms.
    Annals of surgery, 2006, Volume: 243, Issue:2

    Topics: Acute Disease; Anti-Bacterial Agents; Antibiotic Prophylaxis; Aprotinin; Cholecystectomy; Enteral Nutrition; Evidence-Based Medicine; Gabexate; Gastrointestinal Agents; Humans; Imidazoles; Imipenem; Leucine; Meropenem; Octreotide; Pancreatitis; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Randomized Controlled Trials as Topic; Serine Proteinase Inhibitors; Sphincterotomy, Endoscopic; Thienamycins

2006
Role of platelet-activating factor in the pathogenesis of acute pancreatitis.
    World journal of gastroenterology, 2006, Jan-28, Volume: 12, Issue:4

    Topics: Acute Disease; Animals; Apoptosis; Bacterial Translocation; Endothelium, Vascular; Humans; Intestinal Mucosa; Leukocytes; Microcirculation; Pancreatitis; Platelet Activating Factor

2006
The pathogenic mechanism of severe acute pancreatitis complicated with renal injury: a review of current knowledge.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:2

    Topics: Acute Disease; Animals; Humans; Hyperuricemia; Inflammation Mediators; Kidney; Microcirculation; NF-kappa B; Pancreatitis; Phospholipases A2; Platelet Activating Factor; Trypsin; Tumor Necrosis Factor-alpha

2008
Pharmacological approach to acute pancreatitis.
    World journal of gastroenterology, 2008, May-21, Volume: 14, Issue:19

    Topics: Acute Disease; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Evidence-Based Medicine; Gabexate; Humans; Interleukin-10; Nitroglycerin; Octreotide; Pancreatitis; Platelet Activating Factor; Probiotics; Serine Proteinase Inhibitors; Treatment Outcome; Tumor Necrosis Factor-alpha

2008
Platelet activating factor antagonists.
    Advances in pharmacology (San Diego, Calif.), 1995, Volume: 32

    Topics: Animals; Asthma; Humans; Ischemia; Models, Biological; Pancreatitis; Platelet Activating Factor; Reperfusion Injury; Shock, Septic

1995
The role of platelet-activating factor in the pathogenesis of gastrointestinal disease.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 50, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Cholestasis; Colitis, Ulcerative; Crohn Disease; Diarrhea; Digestive System Physiological Phenomena; Enterocolitis, Pseudomembranous; Epithelium; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Hypertension, Portal; Ischemia; Microcirculation; Pancreatitis; Peptic Ulcer; Platelet Activating Factor

1994
Platelet-activating factor.
    Scandinavian journal of gastroenterology. Supplement, 1996, Volume: 219

    Topics: Acute Disease; Clinical Trials as Topic; Humans; Imidazoles; Leucine; Pancreatitis; Platelet Activating Factor

1996
The use of lexipafant in the treatment of acute pancreatitis.
    Advances in experimental medicine and biology, 1996, Volume: 416

    Topics: Acute Disease; Animals; Clinical Trials as Topic; Humans; Imidazoles; Leucine; Monocytes; Pancreatitis; Platelet Activating Factor

1996
Lexipafant (BB-882), a potent PAF antagonist in acute pancreatitis.
    Advances in experimental medicine and biology, 1996, Volume: 416

    Topics: Acute Disease; Animals; Leucine; Pancreatitis; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1996
Acute pancreatitis as a model of sepsis.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41 Suppl A

    Topics: Acute Disease; Cytokines; Endotoxins; Humans; Multiple Organ Failure; Pancreatitis; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Sepsis; Systemic Inflammatory Response Syndrome; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents

1998
Platelet-activating factor and platelet-activating factor antagonists in acute pancreatitis.
    Digestive surgery, 1999, Volume: 16, Issue:2

    Topics: Acute Disease; Animals; Disease Progression; Humans; Pancreatitis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prognosis; Rats; Sensitivity and Specificity; Treatment Outcome

1999
[Inflammatory mediators in the acute pancreatitis].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1999, Volume: 6, Issue:32

    Topics: Acute Disease; Acute-Phase Proteins; Cytokines; Humans; Leukocyte Elastase; Pancreatitis; Platelet Activating Factor

1999
Diagnosis, objective assessment of severity, and management of acute pancreatitis. Santorini consensus conference.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1999, Volume: 25, Issue:3

    Topics: Acute Disease; Anti-Bacterial Agents; Biomarkers; Disease Management; Enteral Nutrition; Humans; Necrosis; Pancreatitis; Platelet Activating Factor; Predictive Value of Tests; Prognosis; Protease Inhibitors; Risk Assessment; Severity of Illness Index; Sphincterotomy, Endoscopic; Tomography, X-Ray Computed; Treatment Outcome

1999
The potential role of therapeutic cytokine manipulation in acute pancreatitis.
    The Surgical clinics of North America, 1999, Volume: 79, Issue:4

    Topics: Acute Disease; Animals; Cytokines; Humans; Inflammation Mediators; Interleukin-1; Interleukin-6; Interleukin-8; Pancreatitis; Platelet Activating Factor; Tumor Necrosis Factor-alpha

1999
The scientific basis of medical therapy of acute pancreatitis. Could it work, and is there a role for lexipafant?
    Gastroenterology clinics of North America, 1999, Volume: 28, Issue:3

    Topics: Acute Disease; Humans; Imidazoles; Leucine; Pancreatitis; Platelet Activating Factor; Randomized Controlled Trials as Topic

1999
[Mediators of the inflammatory response in the course of acute pancreatitis].
    Przeglad lekarski, 1999, Volume: 56, Issue:7-8

    Topics: Acute Disease; Cytokines; Humans; Interleukins; Pancreatitis; Platelet Activating Factor; Tumor Necrosis Factor-alpha

1999
Cytokines and acute pancreatitis.
    Bailliere's best practice & research. Clinical gastroenterology, 1999, Volume: 13, Issue:2

    Topics: Acute Disease; Animals; Clinical Trials as Topic; Cytokines; Humans; Imidazoles; Immunosuppression Therapy; Interleukin-1; Leucine; Leukocytes; Pancreatitis; Platelet Activating Factor; Prognosis; Tumor Necrosis Factor-alpha

1999
The possible role of platelet-activating factor antagonist therapy in the management of severe acute pancreatitis.
    Bailliere's best practice & research. Clinical gastroenterology, 1999, Volume: 13, Issue:2

    Topics: Acute Disease; Adult; Aged; Controlled Clinical Trials as Topic; Female; Humans; Imidazoles; Leucine; Male; Middle Aged; Pancreatitis; Platelet Activating Factor; Prognosis; Severity of Illness Index; Treatment Outcome

1999
Inflammatory mediators as therapeutic targets in acute pancreatitis.
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:4

    Topics: Acute Disease; Chemokines; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-10; Pancreatitis; Platelet Activating Factor; Substance P; Tumor Necrosis Factor-alpha

2001
Importance of microcirculatory disturbances in the pathogenesis of pancreatitis.
    Zentralblatt fur Chirurgie, 2001, Volume: 126, Issue:11

    Topics: Acute Disease; Animals; Capillary Permeability; Chronic Disease; Endothelins; Free Radicals; Humans; Inflammation; Ischemia; Microcirculation; Nitric Oxide; Pancreas; Pancreatitis; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Rats

2001
Influencing factors of pancreatic microcirculatory impairment in acute panceatitis.
    World journal of gastroenterology, 2002, Volume: 8, Issue:3

    Topics: Acute Disease; Bradykinin; Capillary Permeability; Cell Adhesion; Cell Adhesion Molecules; Endothelins; Hemorheology; Humans; Ischemia; Leukocytes; Microcirculation; Nitric Oxide; Pancreas; Pancreatitis; Platelet Activating Factor; Vasoconstriction

2002
[Platelet activating factor as a mediator of lesions of the digestive system].
    Klinicheskaia meditsina, 1990, Volume: 68, Issue:8

    Topics: Animals; Colitis, Ulcerative; Disease Models, Animal; Humans; Liver Cirrhosis, Experimental; Pancreatitis; Peptic Ulcer; Platelet Activating Factor; Rats

1990
Platelet-activating factor (PAF) and its relation to prostaglandins, leukotrienes and other aspects of arachidonate metabolism.
    Prostaglandins, leukotrienes, and essential fatty acids, 1990, Volume: 41, Issue:2

    Topics: Animals; Arachidonic Acids; Asthma; Humans; Hypertension; Leukotrienes; Pancreatitis; Platelet Activating Factor; Prostaglandins

1990

Trials

3 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Pancreatitis

ArticleYear
Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis.
    The British journal of surgery, 1995, Volume: 82, Issue:10

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amylases; C-Reactive Protein; Double-Blind Method; E-Selectin; Female; Humans; Interleukin-6; Interleukin-8; Lipase; Male; Middle Aged; Pancreatitis; Platelet Activating Factor

1995
Platelet-activating factor.
    Scandinavian journal of gastroenterology. Supplement, 1996, Volume: 219

    Topics: Acute Disease; Clinical Trials as Topic; Humans; Imidazoles; Leucine; Pancreatitis; Platelet Activating Factor

1996
Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis.
    Gut, 2001, Volume: 48, Issue:1

    Topics: Acute Disease; Adult; Aged; Biomarkers; Double-Blind Method; E-Selectin; Female; Humans; Imidazoles; Interleukin-8; Length of Stay; Leucine; Logistic Models; Male; Middle Aged; Multiple Organ Failure; Pancreatitis; Placebos; Platelet Activating Factor; Prospective Studies

2001

Other Studies

61 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Pancreatitis

ArticleYear
Effect of platelet-activating factor antagonist WEB 2086 on microcirculatory disorders in acute experimental pancreatitis of graded severity.
    Pancreas, 2009, Volume: 38, Issue:1

    Topics: Amylases; Animals; Azepines; Capillaries; Cell Adhesion; Ceruletide; Disease Models, Animal; Edema; Female; Glycodeoxycholic Acid; Leukocytes; Microcirculation; Oligopeptides; Pancreas; Pancreatitis; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Regional Blood Flow; Severity of Illness Index; Taurocholic Acid; Time Factors; Triazoles

2009
Effect of baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis.
    Pancreas, 2009, Volume: 38, Issue:7

    Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascites; Dinoprostone; Flavonoids; Inflammation Mediators; Interleukin-1beta; Male; Microcirculation; Pancreas; Pancreatitis; Phospholipases A2; Platelet Activating Factor; Random Allocation; Rats; Rats, Sprague-Dawley; Thromboxane B2

2009
A novel role for leucocytes in determining the severity of acute pancreatitis.
    Gut, 2009, Volume: 58, Issue:11

    Topics: Acute Disease; Animals; Biomarkers; Capillaries; Humans; Imidazoles; Inflammation Mediators; Leucine; Leukocytes; Mice; Pancreatitis; Platelet Activating Factor; Prognosis; Severity of Illness Index

2009
Effects of dexamethasone and Salvia miltiorrhizae on the small intestine and immune organs of rats with severe acute pancreatitis.
    Inflammation, 2010, Volume: 33, Issue:4

    Topics: Acute Disease; Animals; Dexamethasone; Drug Evaluation, Preclinical; Interleukin-1beta; Intestinal Mucosa; Intestine, Small; Lymphoid Tissue; Male; Microcirculation; Pancreatitis; Plant Preparations; Platelet Activating Factor; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-2; Reperfusion Injury; Salvia miltiorrhiza; Severity of Illness Index

2010
[Effect of ginkgolide B on plasma levels of interleukin-12 and PAF in severe acute pancreatitis in rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2008, Volume: 24, Issue:2

    Topics: Acute Disease; Animals; Ginkgolides; Interleukin-12; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar

2008
Influence of platelet activating factor on expression of adhesion molecules in experimental pancreatitis.
    World journal of gastroenterology, 2003, Volume: 9, Issue:2

    Topics: Amylases; Animals; Cell Adhesion Molecules; Mice; Mice, Inbred Strains; Pancreas; Pancreatitis; Peroxidase; Platelet Activating Factor

2003
Multimodal management - of value in fulminant acute pancreatitis?
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2003, Volume: 3, Issue:1

    Topics: Acetylcysteine; Acute Disease; Animals; Antibodies, Monoclonal; Capillary Permeability; Drug Therapy, Combination; Free Radical Scavengers; Imidazoles; Leucine; Male; Pancreatitis; Platelet Activating Factor; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley

2003
[The influence of select pathophysiologic factors of acute pancreatitis on erythrocytes' deformability examined in vitro].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2002, Volume: 55, Issue:11-12

    Topics: Acetaldehyde; Acute Disease; Adult; Bilirubin; Cholagogues and Choleretics; Erythrocyte Deformability; Humans; In Vitro Techniques; Lipopolysaccharides; Oxidants; Pancreatitis; Platelet Activating Factor; Superoxides; Taurocholic Acid; Trypsin

2002
An experimental model of hemolysis-induced acute pancreatitis.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2003, Volume: 36, Issue:7

    Topics: Acute Disease; Amylases; Anemia, Hemolytic; Animals; Disease Models, Animal; Hemolysis; Lipase; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2003
[Cytokines and other signal molecules in the pathogenesis of acute pancreatitis].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2003, Issue:9

    Topics: Acute Disease; Acute-Phase Proteins; Animals; Cell Adhesion Molecules; Chemokines; Cytokines; Free Radicals; Humans; Imidazoles; Interleukins; Leucine; Mice; Multiple Organ Failure; Pancreas; Pancreatitis; Platelet Activating Factor; Rabbits; Rats; Selectins; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha

2003
Severity of pancreatitis-associated gut barrier dysfunction is reduced following treatment with the PAF inhibitor lexipafant.
    Biochemical pharmacology, 2005, May-01, Volume: 69, Issue:9

    Topics: Acute Disease; Animals; Capillary Permeability; Chromium Radioisotopes; Endothelium, Vascular; Humans; Imidazoles; Interleukin-1; Interleukin-6; Intestinal Mucosa; Intestine, Small; Iodine Radioisotopes; Leucine; Leukocytes; Male; Pancreatitis; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Serum Albumin; Taurodeoxycholic Acid

2005
Acute pancreatitis affects non-parenchymal liver cells by a mechanism dependent on platelet-activating factor.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2007, Volume: 7, Issue:1

    Topics: Acute Disease; Animals; Azepines; Candida albicans; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitric Oxide; Pancreatitis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Taurocholic Acid; Triazoles; Tumor Necrosis Factors

2007
Significance of platelet activating factor receptor expression in pancreatic tissues of rats with severe acute pancreatitis and effects of BN52021.
    World journal of gastroenterology, 2007, Jun-07, Volume: 13, Issue:21

    Topics: Acute Disease; Amylases; Animals; Fibrinolytic Agents; Gene Expression Regulation; Ginkgolides; Lactones; Male; Pancreatitis; Platelet Activating Factor; Platelet Membrane Glycoproteins; Random Allocation; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; RNA, Messenger

2007
Platelet-activating factor mediates pancreatic function derangement in caerulein-induced pancreatitis in rats.
    Clinical science (London, England : 1979), 1994, Volume: 87, Issue:1

    Topics: Acute Disease; Amylases; Animals; Ascitic Fluid; Ceruletide; Cholecystokinin; Diterpenes; Ginkgolides; Lactones; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar

1994
Platelet-activating factor involvement in the aggravation of acute pancreatitis in rabbits.
    Digestion, 1994, Volume: 55, Issue:4

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Hemodynamics; Lipase; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rabbits

1994
Effect of PAF antagonists on cerulein-induced pancreatitis.
    Journal of lipid mediators and cell signalling, 1995, Volume: 11, Issue:1

    Topics: Acute Disease; Amylases; Animals; Azepines; Capillary Permeability; Ceruletide; Diterpenes; Evans Blue; Ginkgolides; Lactones; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles

1995
The effect of platelet activating factor antagonist (BN 52021) on acute experimental pancreatitis with reference to multiorgan oxidative stress.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1995, Volume: 17, Issue:2

    Topics: Acute Disease; Amylases; Animals; Disease Models, Animal; Diterpenes; Ginkgolides; Lactones; Liver; Lung; Male; Malondialdehyde; Organ Specificity; Oxidative Stress; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Sulfhydryl Compounds

1995
[The role of platelet activating factor in mesenterioangial microcirculatory disturbance complicated with acute pancreatitis in rats].
    Zhonghua yi xue za zhi, 1995, Volume: 75, Issue:3

    Topics: Acute Disease; Animals; Diterpenes; Ginkgolides; Lactones; Male; Microcirculation; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock, Septic; Splanchnic Circulation; Taurocholic Acid

1995
Role of platelet activating factor in acute pancreatitis induced by lipopolysaccharides in rabbits.
    European journal of pharmacology, 1994, Aug-22, Volume: 261, Issue:3

    Topics: Acute Disease; Animals; Escherichia coli; Female; Lipopolysaccharides; Male; Necrosis; Pancreatitis; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1994
Amelioration of experimental acute pancreatitis with a potent platelet-activating factor antagonist.
    The British journal of surgery, 1994, Volume: 81, Issue:12

    Topics: Acute Disease; Animals; Ischemia; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar

1994
Lipid mediator production in acute and chronic pancreatitis in the rat.
    The Journal of surgical research, 1994, Volume: 56, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Chronic Disease; Dinoprostone; Diterpenes; Eicosanoids; Ginkgolides; Lactones; Leukotriene B4; Ligation; Male; Masoprocol; Pancreatic Ducts; Pancreatitis; Platelet Activating Factor; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Thromboxane B2

1994
Release of platelet-activating factor in acute experimental pancreatitis.
    Pancreas, 1993, Volume: 8, Issue:4

    Topics: Acute Disease; Animals; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar

1993
Platelet-activating factor: a mediator of pancreatic inflammation during cerulein hyperstimulation.
    The American journal of pathology, 1993, Volume: 142, Issue:5

    Topics: Animals; Azepines; Calcium; Ceruletide; Male; Osmolar Concentration; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazoles

1993
Evidence for altered cellular calcium in the pathogenetic mechanism of acute pancreatitis in rats.
    The Journal of surgical research, 1996, Volume: 60, Issue:1

    Topics: Acute Disease; Animals; Calcium; Calcium Channel Blockers; Ceruletide; Drug Synergism; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thromboxane B2; Verapamil

1996
Lung injury in the microembolic model of acute pancreatitis and amelioration by lexipafant (BB-882), a platelet-activating factor antagonist.
    Pancreas, 1996, Volume: 13, Issue:2

    Topics: Acute Disease; Animals; Capillary Permeability; Coloring Agents; Evans Blue; Kidney; Leucine; Lung; Lung Diseases; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar

1996
The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis.
    Gastroenterology, 1996, Volume: 111, Issue:4

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Diterpenes; Ginkgolides; Lactones; Lipase; Male; Neutrophils; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

1996
Etiology and pathogenesis of acute pancreatitis--current view.
    Roczniki Akademii Medycznej w Bialymstoku (1995), 1995, Volume: 40, Issue:2

    Topics: Acute Disease; Animals; Free Radicals; Humans; Nitric Oxide; Pancreatitis; Platelet Activating Factor; Reactive Oxygen Species

1995
Free radical enhancement promotes leucocyte recruitment through a PAF and LTB4 dependent mechanism.
    Free radical biology & medicine, 1997, Volume: 22, Issue:6

    Topics: Animals; Diterpenes; Free Radicals; Ginkgolides; Indoles; Lactones; Leukotriene B4; Lipase; Male; Neutrophils; Pancreas; Pancreatitis; Peroxidase; Platelet Activating Factor; Rats; Rats, Wistar; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines

1997
Gene targeting demonstrates additive detrimental effects of interleukin 1 and tumor necrosis factor during pancreatitis.
    Gastroenterology, 1997, Volume: 113, Issue:5

    Topics: Amylases; Animals; Gene Targeting; Interleukin-1; Interleukin-6; Lipase; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatitis; Platelet Activating Factor; Receptors, Interleukin-1; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha

1997
Effect of a platelet-activating factor antagonist on pancreatitis-associated gut barrier dysfunction in rats.
    Pancreas, 1998, Volume: 17, Issue:2

    Topics: Acute Disease; Animals; Bacterial Translocation; Calcium; Capillary Permeability; Endothelium, Vascular; Enterobacteriaceae; Hematocrit; Imidazoles; Intestinal Mucosa; Leucine; Lipase; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Taurodeoxycholic Acid

1998
Hope or hype for lexipafant?
    Nature, 1998, Oct-01, Volume: 395, Issue:6701

    Topics: Clinical Trials as Topic; Humans; Imidazoles; Leucine; Pancreatitis; Platelet Activating Factor

1998
Effect of recombinant platelet-activating factor acetylhydrolase on two models of experimental acute pancreatitis.
    Gastroenterology, 1998, Volume: 115, Issue:5

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acute Disease; Animals; Bile Ducts; Ceruletide; Disease Models, Animal; Gastrointestinal Agents; Ligation; Lung; Lung Diseases; Male; Opossums; Pancreas; Pancreatic Ducts; Pancreatitis; Phospholipases A; Platelet Activating Factor; Rats; Rats, Wistar; Recombinant Proteins

1998
Inhibition of platelet-activating factor, intercellular adhesion molecule 1 and platelet endothelial cell adhesion molecule 1 reduces experimental pancreatitis-associated gut endothelial barrier dysfunction.
    The British journal of surgery, 1999, Volume: 86, Issue:3

    Topics: Animals; Capillaries; Endothelium, Vascular; Gastrointestinal Diseases; Imidazoles; Intercellular Adhesion Molecule-1; Interleukins; Leucine; Leukocytes; Lymphocyte Activation; Male; Pancreatitis; Platelet Activating Factor; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley

1999
Treatment with lexipafant ameliorates the severity of pancreatic microvascular endothelial barrier dysfunction in rats with acute hemorrhagic pancreatitis.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1999, Volume: 25, Issue:1

    Topics: Acute Disease; Animals; Body Water; Capillary Permeability; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Gastrointestinal Hemorrhage; Imidazoles; Interleukin-1; Interleukin-6; Leucine; Male; Microcirculation; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Serum Albumin; Time Factors

1999
Platelet-activating factor antagonist (TCV-309) attenuates the priming effects of bronchoalveolar macrophages in cerulein-induced pancreatitis rats.
    Pancreas, 1999, Volume: 18, Issue:4

    Topics: Animals; Ceruletide; Chemokines, CXC; Chemotactic Factors; Growth Inhibitors; Growth Substances; Hemorrhage; Intercellular Signaling Peptides and Proteins; Isoquinolines; Kinetics; Lipopolysaccharides; Lung; Lung Diseases; Macrophages, Alveolar; Male; Pancreatitis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rats; Rats, Wistar; RNA, Messenger; Sepsis; Tetrahydroisoquinolines

1999
[The role of platelet activating factor in pathogenesis of acute pancreatitis in dogs].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1997, Volume: 35, Issue:2

    Topics: Acute Disease; Amylases; Animals; Diterpenes; Dogs; Female; Ginkgolides; Lactones; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Random Allocation; Taurocholic Acid; Trypsin

1997
The effects of free oxygen radical scavenger and platelet-activating factor antagonist agents in experimental acute pancreatitis.
    Pancreas, 1999, Volume: 19, Issue:2

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Deferoxamine; Disease Models, Animal; Edema; Free Radical Scavengers; Ginkgo biloba; Inflammation; Leukocytes; Luminescent Measurements; Male; Mice; Pancreas; Pancreatitis; Phytotherapy; Plants, Medicinal; Platelet Activating Factor

1999
ICAM-1 in cerulein-induced pancreatitis.
    Gastroenterology, 1999, Volume: 117, Issue:3

    Topics: Animals; Ceruletide; Intercellular Adhesion Molecule-1; Pancreatitis; Platelet Activating Factor

1999
H(2)O(2) and PARS mediate lung P-selectin upregulation in acute pancreatitis.
    Free radical biology & medicine, 2000, Apr-15, Volume: 28, Issue:8

    Topics: Acute Disease; Amylases; Animals; Benzamides; Catalase; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation; Hydrogen Peroxide; Lipase; Lung; Male; P-Selectin; Pancreatitis; Peroxidase; Platelet Activating Factor; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Respiratory Distress Syndrome; Superoxide Dismutase; Taurocholic Acid; Xanthine Oxidase

2000
Pancreatitis-associated ascitic fluid increases intracellular Ca(2+) concentration on hepatocytes.
    The Journal of surgical research, 2000, Volume: 93, Issue:1

    Topics: Acute Disease; Animals; Ascitic Fluid; Calcium; Cells, Cultured; Dogs; Egtazic Acid; Liver; Male; Multiple Organ Failure; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Verapamil

2000
Lysosomal activity of pulmonary alveolar macrophages in acute experimental pancreatitis in rats with reference to positive PAF-antagonist (BN 52021) effect.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2000, Volume: 52, Issue:2

    Topics: Acute Disease; Animals; beta-N-Acetylhexosaminidases; Bronchoalveolar Lavage Fluid; Cathepsin B; Diterpenes; Ginkgolides; Lactones; Lymphocytes; Lysosomes; Macrophages, Alveolar; Male; Neutrophils; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Taurocholic Acid

2000
Platelet activating factor antagonism reduces the systemic inflammatory response in a murine model of acute pancreatitis.
    The Journal of surgical research, 2001, Volume: 99, Issue:2

    Topics: Acute Disease; Amylases; Animals; Disease Models, Animal; Female; Imidazoles; Interleukin-1; Leucine; Lung; Mice; Pancreatitis; Peroxidase; Platelet Activating Factor; Tumor Necrosis Factor-alpha

2001
Relationship between pancreatitis and lung diseases.
    Respiration physiology, 2001, Volume: 128, Issue:1

    Topics: Acute Disease; Animals; Complement C5a; Disease Models, Animal; Female; Humans; Intercellular Adhesion Molecule-1; Lung Diseases; Mice; Mice, Knockout; Neutrophils; Pancreatitis; Platelet Activating Factor; Rats; Receptors, CCR1; Receptors, Chemokine; Substance P

2001
Effects of platelet activating factor antagonist (BN50739) on gut mucosal injury in acute severe pancreatitis in pigs.
    Chinese medical journal, 2000, Volume: 113, Issue:8

    Topics: Acute Disease; Animals; Azepines; Intestinal Mucosa; Pancreatitis; Platelet Activating Factor; Swine; Triazoles

2000
Recent developments in the management of acute pancreatitis.
    Digestive surgery, 2002, Volume: 19, Issue:2

    Topics: Acute Disease; Antibiotic Prophylaxis; Cholangiopancreatography, Endoscopic Retrograde; Drainage; Humans; Imidazoles; Laparoscopy; Leucine; Pancreatitis; Platelet Activating Factor

2002
Platelet activating factor (PAF) inhibitor (TCV-309) reduces caerulein- and PAF-induced pancreatitis. A morphologic and functional study in the rat.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1992, Volume: 43, Issue:4

    Topics: Acute Disease; Animals; Ceruletide; Isoquinolines; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Regional Blood Flow; Tetrahydroisoquinolines

1992
"Cocktail" therapy for acute pancreatitis: combined therapy of protease inhibitor, xanthine oxidase inhibitor and platelet activating factor antagonist in rat caerulein-induced pancreatis.
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1992, Nov-01, Volume: 61, Issue:6

    Topics: Acute Disease; Allopurinol; Animals; Ceruletide; Drug Therapy, Combination; Gabexate; Male; Pancreatitis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Xanthine Oxidase

1992
Role of platelet activating factor in pathogenesis of acute pancreatitis in rats.
    Gut, 1992, Volume: 33, Issue:9

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Isoquinolines; Male; Pancreatic Juice; Pancreatitis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines

1992
Suppression of the Arthus reaction by Y-24180, a potent and specific antagonist of platelet-activating factor.
    Agents and actions, 1992, Volume: 35, Issue:3-4

    Topics: Animals; Arthus Reaction; Azepines; Capillary Permeability; Disease Models, Animal; Female; Guinea Pigs; Male; Molecular Structure; Ovalbumin; Pancreatitis; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Skin; Skin Diseases; Triazoles

1992
Influence of a platelet-activating factor antagonist on severe pancreatitis in two experimental models.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1992, Volume: 12, Issue:2

    Topics: Animals; Ascites; Azepines; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Survival Rate; Triazoles

1992
[The physiopathology of acute pancreatitis: the role of platelet-activating factor (PAF)].
    Revista espanola de enfermedades digestivas, 1992, Volume: 81, Issue:1

    Topics: Acute Disease; Animals; Ascitic Fluid; Biological Assay; Disease Models, Animal; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains

1992
Role of platelet-activating factor in pancreatitis-associated acute lung injury in the rat.
    The American journal of pathology, 1992, Volume: 140, Issue:4

    Topics: Animals; Azepines; Bronchoalveolar Lavage Fluid; Diterpenes; Eicosanoids; Enzymes; Ginkgolides; Lactones; Lung; Pancreatitis; Platelet Activating Factor; Rats; Triazoles

1992
Evidence for platelet-activating factor as a late-phase mediator of chronic pancreatitis in the rat.
    The American journal of pathology, 1990, Volume: 137, Issue:6

    Topics: Amylases; Animals; Azepines; Chronic Disease; Diterpenes; Ginkgolides; Lactones; Ligation; Male; Pancreas; Pancreatic Ducts; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Time Factors; Triazoles

1990
Role of platelet-activating factor in hemodynamic derangements in an acute rodent pancreatic model.
    Gastroenterology, 1992, Volume: 102, Issue:1

    Topics: Acute Disease; Animals; Diterpenes; Ginkgolides; Hemodynamics; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Splanchnic Circulation

1992
Effects of ginkgolide B, a platelet-activating factor inhibitor on insulitis in the spontaneously diabetic BB rat.
    Autoimmunity, 1991, Volume: 9, Issue:3

    Topics: Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Eosinophils; Female; Ginkgolides; Immunohistochemistry; Islets of Langerhans; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred BB

1991
Role of endogenous platelet-activating factor(PAF) in stress-induced hemorrhagic pancreatitis in rats.
    Gastroenterologia Japonica, 1991, Volume: 26, Issue:1

    Topics: Animals; Ceruletide; Male; Pancreatitis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Stress, Physiological

1991
The effect of platelet activating factor antagonist (BN 52021) on cerulein-induced acute pancreatitis with reference to oxygen radicals.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1991, Volume: 8, Issue:1

    Topics: alpha-Amylases; Animals; Ceruletide; Diterpenes; Edema; Free Radicals; Ginkgolides; Lactones; Lipid Peroxidation; Male; Oxygen; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Superoxide Dismutase

1991
Experimental acute pancreatitis induced by platelet activating factor in rabbits.
    The American journal of pathology, 1989, Volume: 134, Issue:2

    Topics: Acute Disease; Amylases; Animals; Blood Chemical Analysis; Female; Ischemia; Male; Microscopy, Electron; Pancreas; Pancreatitis; Platelet Activating Factor; Rabbits

1989
Does acute experimental pancreatitis affect blood platelet function?
    Thrombosis research, 1989, Feb-01, Volume: 53, Issue:3

    Topics: Acute Disease; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Dogs; Hemostasis; In Vitro Techniques; Pancreatitis; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Thromboxane B2

1989
Plasma levels of the lyso-derivative of platelet-activating factor in acute severe systemic illness.
    Clinical science (London, England : 1979), 1989, Volume: 77, Issue:5

    Topics: Acute Disease; Adult; Aged; Aorta, Abdominal; Aortic Aneurysm; Female; Humans; Infections; Male; Middle Aged; Pancreatitis; Platelet Activating Factor; Shock, Cardiogenic

1989
Immune complex induced pancreatitis: effect of BN 52021, a selective antagonist of platelet-activating factor.
    Prostaglandins, 1988, Volume: 35, Issue:5

    Topics: Animals; Capillary Permeability; Disease Models, Animal; Diterpenes; Ginkgolides; Immune Complex Diseases; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains

1988