Compounds > 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
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1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Neutropenia

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with Neutropenia in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199015 (45.45)18.7374
1990's14 (42.42)18.2507
2000's3 (9.09)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blair, IA; Hergott, CB; Mesaros, C; Naidu, NA; Roche, AM; Weiser, JN1
Barberà, JA; Casas, A; Chung, KF; Gabrijelcic, J; Rabinovich, RA; Roca, J; Rodríguez-Roisin, R1
Asano, K; Fukunaga, K; Ishizaka, A; Nakajima, T; Naoki, K; Niimi, K; Oguma, T; Satoh, N; Shiomi, T; Shiraishi, Y; Suzuki, Y; Yamaguchi, K1
Alberton, M; Bussolino, F; Caligaris Cappio, F; Camussi, G; Coda, R; Macchiorlatti, E; Roffinello, C; Segoloni, G; Tetta, C1
Bussolino, F; Camussi, G; Tetta, C1
Björk, J; Smedegård, G1
Bussolino, F; Camussi, G; Chiara Deregibus, M; Segoloni, G; Tetta, C1
Bass, DA; DeChatelet, LR; Lewis, JC; McCall, CE; Miller, CH; O'Flaherty, JT; Waite, M; Wykle, RL1
Crawford, MH; Fitzpatrick, FA; Hanahan, DJ; McManus, LM; O'Rourke, RA; Pinckard, RN1
Demopoulos, CA; Hanahan, DJ; McManus, LM; Pinckard, RN1
Berndt, MC; Coughlan, AF; Dunlop, LC; Hancock, WW; Hau, H1
Filep, JG; Földes-Filep, E; Fournier, A1
Chang, SW1
Barnes, PJ; Carty, TJ; Chung, KF; Eskra, JD; O'Connor, BJ; Uden, S1
Eling, WM; Hermsen, CC; Huys, HL; van der Meer, JW; Vogels, MT1
Barberà, JA; Chung, KF; Lomeña, F; MacNee, W; Masclans, JR; Pavia, J; Piera, C; Roca, J; Rodriguez-Roisin, R1
Battistini, B; Farmer, P; Johnson, RJ; O'Brien, JG; Sirois, P; Zaharia, F1
Barberà, JA; Chung, KF; Gómez, FP; Iglesia, R; Roca, J; Rodriguez-Roisin, R1
Ashida, Y; Kitao, S; Kobayashi, K; Kyotani, K; Mochizuki, T; Nishizono, K; Scott, MA; Tsuchiya, R; Yamada, T1
Kistler, EB; Mitsuoka, H; Schmid-Schönbein, GW1
Goto, F; Yoshikawa, D1
Chen, YH; Morimoto, S; Nakamoto, Y; Ogihara, T; Sakaguchi, K1
Candler, RV; Carroll, RC; Jones, JB; Lothrop, CD; Pratt, HL; Urso, IM1
Barnes, PJ; Chung, KF; Kioumis, I; Lammers, JW; McCusker, M; Nichol, GM1
Keenan, CM; Wallace, JL1
McDonald, JW; Smallbone, BW; Taylor, NE1
Biftu, T; Doebber, TW; Wu, MS2
Mata, R; Muniain, MA; Pérez, JJ; Pozuelo, F; Rodríguez, MC; Rodríguez, MD; Romero, A1
Braquet, P; Cano, E; Fernandez-Gallardo, S; Sanchez Crespo, M1
Barnes, PJ; Chung, KF; McCusker, M; Roberts, NM1
Chang, SW; Feddersen, CO; Henson, PM; Voelkel, NF1
Issekutz, AC; Szpejda, M1

Trials

6 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Neutropenia

ArticleYear
Formoterol protects against platelet-activating factor-induced effects in asthma.
    The European respiratory journal, 2004, Volume: 23, Issue:1

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Airway Resistance; Asthma; Cough; Cross-Over Studies; Double-Blind Method; Dyspnea; Ethanolamines; Female; Flushing; Formoterol Fumarate; Humans; Male; Neutropenia; Platelet Activating Factor; Pulmonary Circulation; Pulmonary Gas Exchange; Ventilation-Perfusion Ratio

2004
Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans.
    American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:1

    Topics: Administration, Inhalation; Administration, Oral; Airway Resistance; Bronchoconstriction; Dihydropyridines; Dose-Response Relationship, Drug; Double-Blind Method; Eicosanoids; Humans; Imidazoles; Leukocyte Count; Leukotriene E4; Male; Neutropenia; Neutrophils; Platelet Activating Factor; Thromboxane B2

1994
Salbutamol reduces pulmonary neutrophil sequestration of platelet-activating factor in humans.
    American journal of respiratory and critical care medicine, 1996, Volume: 154, Issue:2 Pt 1

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Cross-Over Studies; Double-Blind Method; Erythrocytes; Female; Humans; Indium Radioisotopes; Lung; Male; Neutropenia; Neutrophils; Platelet Activating Factor; Radionuclide Imaging; Sodium Pertechnetate Tc 99m

1996
The effects of 5-lipoxygenase inhibition by zileuton on platelet-activating-factor-induced pulmonary abnormalities in mild asthma.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:5 Pt 1

    Topics: Adult; Airway Resistance; Asthma; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxyurea; Leukotrienes; Lipoxygenase Inhibitors; Male; Neutropenia; Oxygen; Platelet Activating Factor; Pulmonary Gas Exchange; Respiratory Mechanics; Ventilation-Perfusion Ratio

1998
Effects of prostacyclin on bronchoconstriction and neutropenia induced by inhaled platelet-activating factor in man.
    The Journal of allergy and clinical immunology, 1990, Volume: 85, Issue:4

    Topics: Administration, Inhalation; Adult; Agranulocytosis; Blood Pressure; Bronchial Spasm; Epoprostenol; Forced Expiratory Flow Rates; Heart Rate; Humans; Infusions, Intravenous; Male; Neutropenia; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Random Allocation

1990
Effect of a PAF antagonist, BN52063, on PAF-induced bronchoconstriction in normal subjects.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:1

    Topics: Adult; Bronchi; Female; Humans; Lactones; Methacholine Compounds; Neutropenia; Plant Extracts; Platelet Activating Factor; Respiratory Function Tests; Skin Tests

1988

Other Studies

27 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Neutropenia

ArticleYear
Bacterial exploitation of phosphorylcholine mimicry suppresses inflammation to promote airway infection.
    The Journal of clinical investigation, 2015, Oct-01, Volume: 125, Issue:10

    Topics: Animals; Bacterial Proteins; Carrier Proteins; Carrier State; Cell Wall; Haemophilus Infections; Haemophilus influenzae; Humans; Immune Evasion; Immunity, Innate; Immunoglobulin D; Lipoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Mimicry; N-Formylmethionine Leucyl-Phenylalanine; Nasal Cavity; Neutropenia; Neutrophil Activation; Neutrophils; Phagocytosis; Phosphorylcholine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pneumococcal Infections; Proteolysis; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Species Specificity; Streptococcus pneumoniae

2015
PAF responsiveness in Japanese subjects with plasma PAF acetylhydrolase deficiency.
    Biochemical and biophysical research communications, 2004, Apr-23, Volume: 317, Issue:1

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Administration, Inhalation; Adult; Alleles; Asthma; Bronchoconstriction; Female; Heterozygote; Homozygote; Humans; Japan; Kinetics; Lymphocytes; Male; Neutropenia; Platelet Activating Factor; Respiratory Function Tests

2004
Effect of prostacyclin (PGI2) on immune-complex-induced neutropenia.
    Immunology, 1983, Volume: 48, Issue:4

    Topics: Agranulocytosis; Animals; Antigen-Antibody Complex; Cell Aggregation; Epoprostenol; Neutropenia; Neutrophils; Platelet Activating Factor; Prostaglandins; Rabbits; Thrombocytopenia

1983
Inhibitory effect of prostacyclin (PGI2) on neutropenia induced by intravenous injection of platelet-activating-factor (PAF) in the rabbit.
    Prostaglandins, 1983, Volume: 25, Issue:3

    Topics: Agranulocytosis; Animals; Epoprostenol; Female; Kinetics; Male; Neutropenia; Platelet Activating Factor; Prostaglandins; Rabbits

1983
Acute microvascular effects of PAF-acether, as studied by intravital microscopy.
    European journal of pharmacology, 1983, Dec-09, Volume: 96, Issue:1-2

    Topics: Animals; Cheek; Cricetinae; Extravasation of Diagnostic and Therapeutic Materials; Indomethacin; Injections, Intravenous; Male; Mesocricetus; Microcirculation; Neutropenia; Platelet Activating Factor; Vasoconstriction

1983
Neutropenia induced by platelet-activating factor (PAF-acether) released from neutrophils: the inhibitory effect of prostacyclin (PGI2).
    Agents and actions, 1981, Volume: 11, Issue:6-7

    Topics: Agranulocytosis; Animals; Cell Aggregation; Epoprostenol; Humans; In Vitro Techniques; Lysophosphatidylcholines; Neutropenia; Neutrophils; Platelet Activating Factor; Prostaglandins; Rabbits

1981
Neutrophil responses to platelet-activating factor.
    Inflammation, 1981, Volume: 5, Issue:3

    Topics: Animals; Glucuronidase; Humans; In Vitro Techniques; Lysophosphatidylcholines; Muramidase; Neutropenia; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Rabbits

1981
Acetyl glyceryl ether phosphorylcholine. Intravascular alterations following intravenous infusion into the baboon.
    Laboratory investigation; a journal of technical methods and pathology, 1981, Volume: 45, Issue:4

    Topics: Animals; Blood Cell Count; Blood Coagulation Factors; Blood Proteins; Hematocrit; Infusions, Parenteral; Lysophosphatidylcholines; Neutropenia; Papio; Platelet Activating Factor; Platelet Factor 4; Species Specificity; Thrombocytopenia; Thromboxane B2; Thromboxanes

1981
Pathobiology of the intravenous infusion of acetyl glyceryl ether phosphorylcholine (AGEPC), a synthetic platelet-activating factor (PAF), in the rabbit.
    Journal of immunology (Baltimore, Md. : 1950), 1980, Volume: 124, Issue:6

    Topics: Animals; Basophils; Blood Platelets; Dose-Response Relationship, Drug; Female; Infusions, Parenteral; Leukocyte Count; Lysophosphatidylcholines; Male; Neutropenia; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Platelet Factor 4; Rabbits; Thrombocytopenia

1980
P-selectin and platelet-activating factor mediate initial endotoxin-induced neutropenia.
    The Journal of experimental medicine, 1994, Jan-01, Volume: 179, Issue:1

    Topics: Animals; Antibodies; Cells, Cultured; Endotoxins; Humans; Male; Neutropenia; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats

1994
Acute pro-inflammatory actions of endothelin-1 in the guinea-pig lung: involvement of ETA and ETB receptors.
    British journal of pharmacology, 1995, Volume: 115, Issue:2

    Topics: Animals; Azepines; Blood Pressure; Bosentan; Bronchopulmonary Sequestration; Capillary Permeability; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Guinea Pigs; In Vitro Techniques; Indoles; Injections, Intravenous; Lung; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Neutrophils; Peptide Fragments; Plasma Volume; Platelet Activating Factor; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate

1995
TNF potentiates PAF-induced pulmonary vasoconstriction in the rat: role of neutrophils and thromboxane A2.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:6

    Topics: Animals; Blood Pressure; Drug Synergism; Imidazoles; In Vitro Techniques; Lipopolysaccharides; Male; Neutropenia; Neutrophils; Platelet Activating Factor; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Thromboxane A2; Thromboxane-A Synthase; Tumor Necrosis Factor-alpha; Vasoconstriction

1994
Roles of tumor necrosis factor alpha, granulocyte-macrophage colony-stimulating factor, platelet-activating factor, and arachidonic acid metabolites in interleukin-1-induced resistance to infection in neutropenic mice.
    Infection and immunity, 1994, Volume: 62, Issue:5

    Topics: Animals; Arachidonic Acid; Female; Gram-Negative Bacterial Infections; Granulocyte-Macrophage Colony-Stimulating Factor; Immunoglobulin G; Interleukin-1; Mice; Neutropenia; Platelet Activating Factor; Tumor Necrosis Factor-alpha

1994
Effects of tranexamic acid and aprotinin on PAF-induced vascular permeability in normal, thrombocytopenic or neutropenic rats.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46 Suppl 2

    Topics: Animals; Antifibrinolytic Agents; Aprotinin; Bronchi; Capillary Permeability; Male; Neutropenia; Platelet Activating Factor; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Thrombocytopenia; Trachea; Tranexamic Acid; Trypsin Inhibitors

1997
Role of platelet activating factor in development of thrombocytopenia and neutropenia in dogs with endotoxemia.
    American journal of veterinary research, 1999, Volume: 60, Issue:2

    Topics: Animals; Blood Coagulation Tests; Dog Diseases; Dogs; Endotoxemia; Female; Isoquinolines; Leukocyte Count; Lipopolysaccharides; Male; Neutropenia; Pilot Projects; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Count; Pyridinium Compounds; Radioimmunoassay; Tetrahydroisoquinolines; Thrombocytopenia

1999
Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock.
    Shock (Augusta, Ga.), 2002, Volume: 17, Issue:3

    Topics: Animals; Blood Pressure; Endopeptidases; Esters; Gabexate; Guanidines; Humans; In Vitro Techniques; Inflammation; Intestinal Mucosa; Intestines; Leukocytes; Male; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phospholipases A; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion; Serine Endopeptidases; Serine Proteinase Inhibitors; Shock; Splanchnic Circulation; Survival Rate

2002
Effect of platelet-activating factor antagonist and leukotriene antagonist on endotoxin shock in the rat: role of the leukocyte.
    Circulatory shock, 1992, Volume: 38, Issue:1

    Topics: Animals; Chromones; Leukocyte Count; Leukocytes; Leukotriene Antagonists; Male; Neutropenia; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Wistar; Shock, Septic; Vinblastine

1992
Increases in circulating level of platelet-activating factor lag behind transient neutropenia during hemodialysis with cuprophane membranes.
    Nephron, 1991, Volume: 59, Issue:3

    Topics: Adult; Aged; Cellulose; Complement System Proteins; Humans; Kidney Failure, Chronic; Kidneys, Artificial; Male; Middle Aged; Neutropenia; Platelet Activating Factor; Platelet Count; Renal Dialysis

1991
Characterization of platelet function in cyclic hematopoietic dogs.
    Experimental hematology, 1991, Volume: 19, Issue:9

    Topics: Animals; Blood Proteins; Dog Diseases; Dogs; Female; Hematopoiesis; Heterozygote; Male; Neutropenia; Periodicity; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Storage Pool Deficiency; Thrombin; Type C Phospholipases

1991
Leukotriene B4 potentiates colonic ulceration in the rat.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:5

    Topics: Administration, Rectal; Animals; Colitis; Drug Synergism; Ethanol; Leukotriene B4; Leukotrienes; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Platelet Activating Factor; Rats; Rats, Inbred Strains; Ulcer

1990
Effects of L-652,731, a platelet-activating factor (PAF) receptor antagonist, on PAF- and complement-induced pulmonary hypertension in sheep.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Animals; Aspirin; Complement Activation; Complement System Proteins; Dose-Response Relationship, Drug; Endotoxins; Female; Furans; Hypertension, Pulmonary; Hypoxia; Neutropenia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sheep; Thromboxanes; Zymosan

1987
Platelet-activating factor (PAF) mediation of rat anaphylactic responses to soluble immune complexes. Studies with PAF receptor antagonist L-652,731.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Jun-15, Volume: 136, Issue:12

    Topics: Anaphylaxis; Animals; Antigen-Antibody Complex; Capillary Permeability; Female; Furans; Hydrolases; Hypotension; Kinetics; Liver; Lysosomes; Neutropenia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1986
[Effect of corticosteroids, quinacrine and L-652, 731 on experimental aggregation of polymorphonuclear leukocytes induced by complement and platelet activating factor (PAF)].
    Revista espanola de fisiologia, 1988, Volume: 44, Issue:4

    Topics: Agranulocytosis; Animals; Cell Aggregation; Complement System Proteins; Furans; Methylprednisolone; Methylprednisolone Hemisuccinate; Neutropenia; Platelet Activating Factor; Quinacrine; Rabbits; Zymosan

1988
Role of paf-acether in the mediation of pathophysiological responses to aggregated immunoglobulins. Studies with the platelet-activating factor receptor antagonist BN 52021.
    International journal of immunopharmacology, 1988, Volume: 10, Issue:4

    Topics: Acetylglucosaminidase; Animals; Diterpenes; Ginkgolides; Humans; Immunoglobulin G; Lactones; Metabolic Clearance Rate; Neutropenia; Platelet Activating Factor; Rats; Rats, Inbred Strains; Tissue Plasminogen Activator

1988
Platelet-activating factor mediates hemodynamic changes and lung injury in endotoxin-treated rats.
    The Journal of clinical investigation, 1987, Volume: 79, Issue:5

    Topics: Animals; Blood Pressure; Endotoxins; Hemodynamics; Lung; Male; Neutropenia; Phospholipid Ethers; Platelet Activating Factor; Pulmonary Circulation; Quinolinium Compounds; Rats; Rats, Inbred Strains; Salmonella enteritidis; Thiazoles; Time Factors; Vasoconstriction; Vinblastine

1987
Inhibition of the platelet activating factor (PAF)-induced in vivo responses in rats by trans-2,5-(3,4,5-trimethoxyphenyl) tetrahydrofuran (L-652,731), a PAF receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: Acetylglucosaminidase; Animals; Blood Pressure; Endotoxins; Female; Furans; Hydrolases; Leukopenia; Lysosomes; Neutropenia; Platelet Activating Factor; Rats; Rats, Inbred Strains

1986
Evidence that platelet activating factor may mediate some acute inflammatory responses. Studies with the platelet-activating factor antagonist, CV3988.
    Laboratory investigation; a journal of technical methods and pathology, 1986, Volume: 54, Issue:3

    Topics: Acute Disease; Animals; Blood Platelets; Capillary Permeability; Cell Movement; Inflammation; Leukocytes; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phospholipid Ethers; Platelet Activating Factor; Rabbits; Regional Blood Flow; Serum Albumin; Skin; Thiazoles; Thrombocytopenia

1986