Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Necrosis

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with Necrosis in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199010 (18.87)18.7374
1990's38 (71.70)18.2507
2000's5 (9.43)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bennett, SA; Bonin, F; Brewer, C; Bullock, P; Franks, DJ; Imbeault, S; Morin, J; Nault, MC; Shen, TY1
Kawasaki, T; Kobayashi, Y; Murohisa, G; Nakamura, H; Nakamura, S1
Alloatti, G; Berta, G; Cappello, S; Gattullo, D; Losano, G; Mognetti, B; Pagliaro, P; Penna, C1
Aladağ, M; Ara, C; Demirel, U; Firat, S; Harputluoglu, MM; Hilmioğlu, F; Karadağ, N; Karincaoğlu, M; Temel, I; Yücel, N1
Adams, JG; Dhar, A; Shukla, SD; Silver, D1
Caplan, MS; Hsueh, W; Huang, W; MacKendrick, W; Sun, XM; Tien, J1
Battaglia, E; Camussi, G; De Giuli, P; De Martino, A; Dughera, L; Emanuelli, G; Gaia, E; Gubetta, L; Lupia, E; Montrucchio, G1
Crawford, SE; Hsueh, W; Huang, L; Tan, X1
Caplan, MS; Hsueh, W; Liu, Y; Sun, X1
Furió, V; Pellón, MI; Sánchez Crespo, M; Steil, AA1
Patterson, JS; Provost, PJ; Stick, JA; Wilson, DV1
Caplan, M; Hsueh, W; MacKendrick, W1
Furukawa, M; Johnston, JM; Lee, EL1
Altavilla, D; Bussolino, F; Calapai, G; Campo, GM; Canale, P; Caputi, AP; Ioculano, M; Saitta, A; Squadrito, F; Zingarelli, B1
Baba, S; Muro, H; Nakamura, S; Onuki, Y1
Borobia, FG; Escriba, JM; Fabregat, J; Farran, L; Figueras, J; Jaurrieta, E; Rafecas, A; Torras, J1
Ito, Y; Miki, H; Saito, K; Sugatani, J; Uyama, M1
Aguirre, B; Alvarez, T; Fernandez, L; González-Fajardo, JA; Ramos, G; Vaquero, C1
Bree, M; Granger, DN; Hsueh, W; Huang, W; Qu, XW; Sun, XM1
Adams, JG; Dhar, A; Shukla, S; Silver, D; Slocum, M1
Adler, L; Caplan, MS; Hedlund, E; Hsueh, W; Lickerman, M1
Bailie, MB; Fink, GD; Pearson, JM; Roth, RA1
Gonzalez-Crussi, F; Hsueh, W; Huang, W; Qu, X; Rozenfeld, RA; Sun, X1
Chang, H; Gonzalez-Crussi, F; Hsueh, W; Qu, XW; Remick, DG; Tan, XD; Wang, H1
Bitler, CM; Pulliam, L; Stubblebine, M; Zhou, M1
Bulkley, GB; Hsueh, W; Huang, W; Qu, XW; Rozenfeld, RA1
Fink, MP1
Hsueh, W; Huang, W; Qu, XW; Rozenfeld, RA; Sun, X; Tan, XD1
Bassi, C; Bradley, E; Dervenis, C; Imrie, CW; Johnson, CD; McMahon, MJ; Modlin, I1
Aksungar, FB; Bilsel, S; Bozkurt, A; Cetinel, U; Coşkun, T; Granger, DN; Haklar, G; Kurtel, H; Oktar, BK; Yegen, BC; Yüksel, M1
Levine, BA; McCollum, MO; Olson, MS; Zhou, W1
Chakrabarty, S; Flores, NA; Fluck, DS; Sheridan, DJ1
al Attiyah, R; Rook, GA; Rosen, H1
Caplan, MS; Hsueh, W; Kelly, A; Zhang, C1
Caplan, MS; Hsueh, W; Sun, XM1
Carter, EA; Schiffrin, EJ; Schroeder, S; Trop, M1
Chakrabarty, S; Sheridan, DJ; Thomas, P1
Carter, EA; Schiffrin, EJ; Trop, M1
Hsueh, W; Zhang, C1
Hara, A; Ikeda, M; Kaneko, H; Shiba, T; Takeuchi, S; Yoshida, H1
Hsueh, W; Sun, XM3
Ichikawa, Y; Kioka, K; Kobayashi, K; Mizoguchi, Y; Morisawa, S; Yamamoto, S1
Krieglstein, J; Mennel, HD; Oberpichler, H; Rossberg, C; Sauer, D1
Lee, TC; Malone, B; Snyder, F; Woodard, D1
Gonzalez-Crussi, F; Hsueh, W1
Arroyave, JL; Gonzalez-Crussi, F; Hsueh, W3
Wallace, JL; Whittle, BJ1
Braquet, P; Drouet, Y; Droy-Lefaix, MT; Geraud, G1
Anderson, RC; Arroyave, JL; Gonzalez-Crussi, F; Houlihan, WJ; Hsueh, W; Lee, ML1

Reviews

4 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Necrosis

ArticleYear
Nitric oxide and the gut: one more piece in the puzzle.
    Critical care medicine, 1999, Volume: 27, Issue:2

    Topics: Animals; Intestinal Mucosa; Intestines; Necrosis; Nitric Oxide; Platelet Activating Factor; Rats

1999
Diagnosis, objective assessment of severity, and management of acute pancreatitis. Santorini consensus conference.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1999, Volume: 25, Issue:3

    Topics: Acute Disease; Anti-Bacterial Agents; Biomarkers; Disease Management; Enteral Nutrition; Humans; Necrosis; Pancreatitis; Platelet Activating Factor; Predictive Value of Tests; Prognosis; Protease Inhibitors; Risk Assessment; Severity of Illness Index; Sphincterotomy, Endoscopic; Tomography, X-Ray Computed; Treatment Outcome

1999
Hypoxia, PAF, and necrotizing enterocolitis.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Azepines; Enterocolitis; Humans; Hypoxia; Intestines; Necrosis; Platelet Activating Factor; Quinolinium Compounds; Triazoles

1991
Ischemic bowel necrosis induced by platelet-activating factor: an experimental model.
    Methods and achievements in experimental pathology, 1988, Volume: 13

    Topics: Animals; Complement Activation; Disease Models, Animal; Endotoxins; Enterocolitis, Pseudomembranous; Intestine, Small; Ischemia; Necrosis; Platelet Activating Factor; Rats

1988

Other Studies

49 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Necrosis

ArticleYear
Platelet activating factor-induced apoptosis is inhibited by ectopic expression of the platelet activating factor G-protein coupled receptor.
    Journal of neurochemistry, 2002, Volume: 82, Issue:6

    Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cytoprotection; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; In Situ Nick-End Labeling; Micelles; Necrosis; PC12 Cells; Pheochromocytoma; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Transfection

2002
Involvement of platelet-activating factor in hepatic apoptosis and necrosis in chronic ethanol-fed rats given endotoxin.
    Liver, 2002, Volume: 22, Issue:5

    Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Therapy, Combination; Escherichia coli; Ethanol; Fas Ligand Protein; fas Receptor; Hepatitis, Alcoholic; Immunoenzyme Techniques; In Situ Nick-End Labeling; Isoquinolines; Lipopolysaccharides; Liver; Male; Membrane Glycoproteins; Necrosis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines

2002
Platelet-activating factor induces cardioprotection in isolated rat heart akin to ischemic preconditioning: role of phosphoinositide 3-kinase and protein kinase C activation.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5

    Topics: Alkaloids; Animals; Azepines; Benzophenanthridines; Cardiotonic Agents; Chromones; Coronary Circulation; Enzyme Inhibitors; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Morpholines; Myocardial Reperfusion Injury; Myocardium; Necrosis; Perfusion; Phenanthridines; Phosphatidylinositol 3-Kinases; Platelet Activating Factor; Platelet Aggregation Inhibitors; Protein Kinase C; Rats; Rats, Wistar; Triazoles; Ventricular Function, Left

2005
The effects of Gingko biloba extract on acetic acid-induced colitis in rats.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2006, Volume: 17, Issue:3

    Topics: Acetic Acid; Animals; Antioxidants; Biomarkers; Colitis; Disease Models, Animal; Fibrosis; Ginkgo biloba; Intestinal Mucosa; Male; Malondialdehyde; Necrosis; Oxidative Stress; Phytotherapy; Plant Extracts; Platelet Activating Factor; Rats; Rats, Wistar

2006
Effect of pentoxifylline on tissue injury and platelet-activating factor production during ischemia-reperfusion injury.
    Journal of vascular surgery, 1995, Volume: 21, Issue:5

    Topics: Animals; Blood Pressure; Dogs; Female; Heart Rate; Infusions, Intravenous; Models, Cardiovascular; Muscle, Skeletal; Necrosis; Organ Size; Pentoxifylline; Platelet Activating Factor; Reperfusion Injury; Time Factors

1995
Endogenous bacterial toxins are required for the injurious action of platelet-activating factor in rats.
    Gastroenterology, 1995, Volume: 109, Issue:1

    Topics: Analysis of Variance; Animals; Bacterial Toxins; Drug Therapy, Combination; Endotoxins; Intestines; Male; Metronidazole; Necrosis; Neomycin; Platelet Activating Factor; Polymyxin B; Rats; Rats, Sprague-Dawley; Shock; Specific Pathogen-Free Organisms

1995
Role of platelet activating factor in acute pancreatitis induced by lipopolysaccharides in rabbits.
    European journal of pharmacology, 1994, Aug-22, Volume: 261, Issue:3

    Topics: Acute Disease; Animals; Escherichia coli; Female; Lipopolysaccharides; Male; Necrosis; Pancreatitis; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1994
Platelet-activating factor and endotoxin induce tumour necrosis factor gene expression in rat intestine and liver.
    Immunology, 1994, Volume: 83, Issue:1

    Topics: Animals; Blotting, Northern; Drug Synergism; Gene Expression Regulation; Intestine, Small; Lipopolysaccharides; Liver; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; RNA, Messenger; Shock, Septic; Tumor Necrosis Factor-alpha

1994
Endotoxin-resistant mice are protected from PAF-induced bowel injury and death. Role of TNF, complement activation, and endogenous PAF production.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:3

    Topics: Animals; Complement Activation; Endotoxins; Intestine, Small; Male; Mice; Mice, Inbred C3H; Necrosis; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Shock, Septic; Tumor Necrosis Factor-alpha

1995
Study of the effector mechanism involved in the production of haemorrhagic necrosis of the small intestine in rat passive anaphylaxis.
    British journal of pharmacology, 1994, Volume: 112, Issue:4

    Topics: Anaphylaxis; Animals; Blood Pressure; Capillary Permeability; Complement System Proteins; Dinitrophenols; Gastrointestinal Hemorrhage; Intestine, Small; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Tumor Necrosis Factor-alpha

1994
Histologic and ultrastructural changes after large-colon torsion, with and without use of a specific platelet-activating factor antagonist (WEB 2086), in ponies.
    American journal of veterinary research, 1994, Volume: 55, Issue:5

    Topics: Animals; Azepines; Colon; Colonic Diseases; Edema; Epithelium; Female; Horse Diseases; Horses; Intestinal Mucosa; Male; Microscopy, Electron; Necrosis; Neutrophils; Platelet Activating Factor; Torsion Abnormality; Triazoles

1994
Endogenous nitric oxide protects against platelet-activating factor-induced bowel injury in the rat.
    Pediatric research, 1993, Volume: 34, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Enterocolitis, Pseudomembranous; Hematocrit; Intestines; Male; Mesenteric Artery, Superior; Necrosis; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Superoxides

1993
Platelet-activating factor-induced ischemic bowel necrosis: the effect of platelet-activating factor acetylhydrolase.
    Pediatric research, 1993, Volume: 34, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Disease Models, Animal; Enterocolitis, Pseudomembranous; Female; Humans; Infant, Newborn; Intestines; Ischemia; Milk, Human; Necrosis; Phospholipases A; Platelet Activating Factor; Rats; Rats, Wistar

1993
Platelet activating factor interaction with tumor necrosis factor in myocardial ischaemia-reperfusion injury.
    Journal of lipid mediators, 1993, Volume: 8, Issue:1

    Topics: Analysis of Variance; Animals; Biological Assay; Creatine Kinase; Isoenzymes; Leukopenia; Macrophages; Male; Myocardial Ischemia; Myocardial Reperfusion; Necrosis; Peroxidase; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha

1993
[Experimental studies on the relation of platelet activating factor (PAF) to high mortality in sublethal endotoxemia after massive hepatectomy and effects of its antagonist].
    Nihon Geka Gakkai zasshi, 1993, Volume: 94, Issue:5

    Topics: Animals; Disseminated Intravascular Coagulation; Endotoxins; Escherichia coli; Hepatectomy; Liver; Male; Necrosis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Shock, Septic

1993
Platelet-activating factor antagonist BN52021 improves survival in normothermic liver ischemia in rats.
    Transplantation proceedings, 1993, Volume: 25, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Graft Survival; Ischemia; Lactones; Liver Circulation; Liver Transplantation; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Wistar; Reperfusion Injury

1993
Corneal PAF acetylhydrolase increases in anterior segment ischemia in rabbits.
    Experimental eye research, 1993, Volume: 57, Issue:1

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Anterior Eye Segment; Cornea; Ischemia; Male; Necrosis; Phospholipases A; Platelet Activating Factor; Rabbits; Time Factors

1993
Protective effect of a platelet-activating factor antagonist (WEB-2086) in postischemic renal failure.
    Annals of vascular surgery, 1996, Volume: 10, Issue:1

    Topics: Acute Kidney Injury; Animals; Azepines; Disease Models, Animal; Diuresis; Female; Ischemia; Kidney; Kidney Function Tests; Male; Necrosis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Triazoles

1996
Role of leukocyte beta 2-integrin in PAF-induced shock and intestinal injury.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 1

    Topics: Animals; Antibodies; Blood Pressure; CD18 Antigens; Intestine, Small; Leukocyte Count; Leukocytes; Macrophage-1 Antigen; Male; Necrosis; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock

1996
Role of platelet-activating factor in skeletal muscle ischemia-reperfusion injury.
    Advances in experimental medicine and biology, 1996, Volume: 416

    Topics: Animals; Azepines; Dogs; Female; Heart Rate; In Vitro Techniques; Ischemia; Muscle, Skeletal; Necrosis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Reperfusion Injury; Triazoles

1996
The platelet-activating factor receptor antagonist WEB 2170 prevents neonatal necrotizing enterocolitis in rats.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 24, Issue:3

    Topics: Animals; Animals, Newborn; Azepines; Enterocolitis, Pseudomembranous; Intestinal Mucosa; Intestine, Small; Necrosis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1997
Neither platelet activating factor nor leukotrienes are critical mediators of liver injury after lipopolysaccharide administration.
    Toxicology, 1997, Sep-05, Volume: 121, Issue:3

    Topics: Administration, Oral; Alanine Transaminase; Animals; Azepines; Blood Platelets; Chemical and Drug Induced Liver Injury; Female; Fibrinogen; Hydroxyurea; Injections, Intraperitoneal; Injections, Intravenous; Leukotrienes; Lipopolysaccharides; Lipoxygenase Inhibitors; Liver; Liver Diseases; Necrosis; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombocytopenia; Triazoles

1997
P-selectin-deficient mice are protected from PAF-induced shock, intestinal injury, and lethality.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1

    Topics: Animals; Anticoagulants; CD18 Antigens; Death; Hypotension; Intercellular Adhesion Molecule-1; Intestine, Small; Intestines; Leukocyte-Adhesion Deficiency Syndrome; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Necrosis; P-Selectin; Platelet Activating Factor; Polysaccharides; Rats; Shock; Species Specificity

1997
Platelet-activating factor (PAF) up-regulates plasma and tissue PAF-acetylhydrolase activity in the rat: effect of cycloheximide.
    Pediatric research, 1997, Volume: 42, Issue:5

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Cycloheximide; Intestinal Mucosa; Intestines; Male; Necrosis; Phospholipases A; Platelet Activating Factor; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Up-Regulation

1997
Differential modulation of cell death proteins in human brain cells by tumor necrosis factor alpha and platelet activating factor.
    Journal of neuroscience research, 1998, Nov-15, Volume: 54, Issue:4

    Topics: AIDS Dementia Complex; Apoptosis; Astrocytes; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Brain; Cell Aggregation; Cells, Cultured; DNA Fragmentation; Gene Expression Regulation; Humans; Necrosis; Neurons; Oligodendroglia; Platelet Activating Factor; Protein Isoforms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Transfection; Tumor Necrosis Factor-alpha

1998
The role of xanthine oxidase in platelet activating factor induced intestinal injury in the rat.
    Gut, 1999, Volume: 44, Issue:2

    Topics: Allopurinol; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelium; Ileum; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Xanthine Dehydrogenase; Xanthine Oxidase

1999
Roles of nitric oxide synthases in platelet-activating factor-induced intestinal necrosis in rats.
    Critical care medicine, 1999, Volume: 27, Issue:2

    Topics: Animals; Drug Evaluation, Preclinical; Enzyme Inhibitors; Intestine, Small; Male; Necrosis; Neutrophils; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Activating Factor; Prospective Studies; Random Allocation; Rats; Rats, Sprague-Dawley; Shock

1999
Endothelin-1-induced PMN infiltration and mucosal dysfunction in the rat small intestine.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Azepines; Cell Movement; Endothelin-1; Female; Injections, Intra-Arterial; Intercellular Adhesion Molecule-1; Intestinal Mucosa; Intestine, Small; Luminescent Measurements; Male; Necrosis; Neutrophils; Oxidative Stress; Peroxidase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Triazoles

2000
Inflammation and platelet-activating factor production during hepatic ischemia/reperfusion.
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:5

    Topics: Alanine Transaminase; Allopurinol; Animals; Azepines; Gadolinium; Hepatitis; Ischemia; Leukocytes; Liver; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Triazoles

1992
Effects of the PAF antagonists BN50726 and BN50739 on arrhythmogenesis and extent of necrosis during myocardial ischaemia/reperfusion in rabbits.
    British journal of pharmacology, 1992, Volume: 107, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Azepines; Blood Pressure; Electrocardiography; Heart Rate; Hemodynamics; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Necrosis; Platelet Activating Factor; Rabbits; Thienopyridines; Triazoles

1992
A model for the investigation of factors influencing haemorrhagic necrosis mediated by tumour necrosis factor in tissue sites primed with mycobacterial antigen preparations.
    Clinical and experimental immunology, 1992, Volume: 88, Issue:3

    Topics: Animals; Antigens, Bacterial; Complement System Proteins; Elapid Venoms; Female; Hemorrhage; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Misoprostol; Mycobacterium; Necrosis; Platelet Activating Factor; Skin Diseases; Tumor Necrosis Factor-alpha

1992
Platelet activating factor-induced shock and intestinal necrosis in the rat: role of endogenous platelet-activating factor and effect of saline infusion.
    Critical care medicine, 1991, Volume: 19, Issue:8

    Topics: Animals; Azepines; Intestine, Large; Isotonic Solutions; Male; Necrosis; Peroxidase; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock; Sodium Chloride; Triazoles

1991
Platelet-activating factor induces intestinal necrosis, but not septic shock, in germ-free and specific-pathogen-free rodents.
    Burns : journal of the International Society for Burn Injuries, 1991, Volume: 17, Issue:4

    Topics: Animals; Female; Germ-Free Life; Intestine, Small; Lipopolysaccharides; Mice; Mice, Inbred C3H; Necrosis; Platelet Activating Factor; Rats; Salmonella typhi; Shock, Septic; Specific Pathogen-Free Organisms

1991
Contribution of platelets and platelet-activating factor (PAF) to the arrhythmogenic, haemodynamic and necrotic effects of acute myocardial ischaemia.
    European heart journal, 1991, Volume: 12, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Blood Platelets; Diterpenes; Ginkgolides; Hypotension; Imidazoles; Immune Sera; Lactones; Myocardial Infarction; Necrosis; Platelet Activating Factor; Platelet Activation; Pyridines; Rabbits; Thromboxane A2; Thromboxane-A Synthase

1991
Effect of platelet activating factor on reticuloendothelial system function.
    Burns : journal of the International Society for Burn Injuries, 1991, Volume: 17, Issue:3

    Topics: Animals; Burns; Cecum; Disease Models, Animal; Injections, Intravenous; Intestine, Small; Mononuclear Phagocyte System; Necrosis; Platelet Activating Factor; Rats; Stomach; Technetium Tc 99m Sulfur Colloid

1991
PAF-induced bowel necrosis. Effects of vasodilators.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:5

    Topics: Alprostadil; Animals; Hydralazine; Hypotension; Indazoles; Intestinal Diseases; Leukopenia; Male; Mesenteric Arteries; Necrosis; Nitroglycerin; Phenoxybenzamine; Platelet Activating Factor; Prazosin; Rats; Rats, Inbred Strains; SRS-A; Vasodilator Agents

1991
Mechanism of acute gastrointestinal mucosal damage in endotoxic shock and the effect of Fragmin.
    Seminars in thrombosis and hemostasis, 1990, Volume: 16 Suppl

    Topics: Acute Disease; Animals; Benzoquinones; Dogs; Gastric Mucosa; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Intestinal Mucosa; Leukotriene B4; Lipoxygenase Inhibitors; Necrosis; Phospholipid Ethers; Platelet Activating Factor; Shock, Septic

1990
Platelet-activating factor produces shock, in vivo complement activation, and tissue injury in mice.
    Journal of immunology (Baltimore, Md. : 1950), 1991, Jul-15, Volume: 147, Issue:2

    Topics: Animals; Blood Pressure; Complement Activation; Complement C5; Dose-Response Relationship, Drug; Hematocrit; Intestinal Diseases; Leukocyte Count; Lipopolysaccharides; Mice; Mice, Mutant Strains; Necrosis; Neutrophils; Platelet Activating Factor; Shock; Tumor Necrosis Factor-alpha; Vinblastine

1991
Possible involvement of platelet-activating factor in the induction of liver cell injury.
    Osaka city medical journal, 1990, Volume: 36, Issue:2

    Topics: Animals; Cell Adhesion; Liver; Male; Mice; Mice, Inbred BALB C; Necrosis; Platelet Activating Factor

1990
PAF antagonist ginkgolide B reduces postischemic neuronal damage in rat brain hippocampus.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1990, Volume: 10, Issue:1

    Topics: Animals; Brain Ischemia; Cell Survival; Diterpenes; Ginkgolides; Hippocampus; Lactones; Male; Necrosis; Neurons; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains

1990
Tumor necrosis factor-induced bowel necrosis: the role of platelet-activating factor.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1989, Volume: 19

    Topics: Animals; Drug Synergism; Intestines; Leukopenia; Lipopolysaccharides; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Recombinant Proteins; Thiazoles; Tumor Necrosis Factor-alpha

1989
Renal necrosis and the involvement of a single enzyme of the de novo pathway for the biosynthesis of platelet-activating factor in the rat kidney inner medulla.
    Biochemical and biophysical research communications, 1989, Sep-15, Volume: 163, Issue:2

    Topics: Animals; Diacylglycerol Cholinephosphotransferase; Ethylamines; Kidney; Kidney Cortex; Kidney Medulla; Microsomes; Necrosis; Platelet Activating Factor; Rats

1989
Platelet-activating factor-induced ischemic bowel necrosis. An investigation of secondary mediators in its pathogenesis.
    The American journal of pathology, 1986, Volume: 122, Issue:2

    Topics: Alprostadil; Animals; Blood Pressure; Catechols; Chromones; Diethylcarbamazine; Disease Models, Animal; Hematocrit; Indomethacin; Intestines; Ischemia; Leukocyte Count; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Masoprocol; Methacrylates; Necrosis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salmonella typhi; Thromboxane-A Synthase; Verapamil

1986
Effects of inhibitors of arachidonic acid metabolism on Paf-induced gastric mucosal necrosis and haemoconcentration.
    British journal of pharmacology, 1986, Volume: 89, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Pressure; Dexamethasone; Gastric Mucosa; Hematocrit; Male; Necrosis; Platelet Activating Factor; Prednisolone; Pyrazoles; Rats; Rats, Inbred Strains

1986
The amplificative role of PAF-acether in the oxidative stress following reperfusion of ischemic stomach.
    Basic life sciences, 1988, Volume: 49

    Topics: Allopurinol; Animals; Female; Free Radicals; Gastric Mucosa; Ischemia; Necrosis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reference Values; Reperfusion Injury; Stomach; Superoxide Dismutase

1988
Sequential release of leukotrienes and norepinephrine in rat bowel after platelet-activating factor. A mechanistic study of platelet-activating factor-induced bowel necrosis.
    Gastroenterology, 1988, Volume: 94, Issue:6

    Topics: Animals; Catecholamines; Disease Models, Animal; Guinea Pigs; Intestine, Small; Ischemia; Male; Necrosis; Norepinephrine; Platelet Activating Factor; Rats; SRS-A; Vasoconstriction

1988
Bowel necrosis induced by tumor necrosis factor in rats is mediated by platelet-activating factor.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:5

    Topics: Animals; Digestive System; Disease Models, Animal; Ischemia; Lipopolysaccharides; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha

1988
Platelet-activating factor: an endogenous mediator for bowel necrosis in endotoxemia.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1987, Volume: 1, Issue:5

    Topics: Animals; Intestines; Ischemia; Lipopolysaccharides; Necrosis; Platelet Activating Factor; Rats; Salmonella typhi

1987
Platelet activating factor-induced ischemic bowel necrosis: the effect of PAF antagonists.
    European journal of pharmacology, 1986, Apr-09, Volume: 123, Issue:1

    Topics: Animals; Body Weight; Hematocrit; Intestine, Small; Ischemia; Lipopolysaccharides; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Splanchnic Circulation; Thiazoles

1986