1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with MODS in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.03) | 18.7374 |
| 1990's | 18 (54.55) | 18.2507 |
| 2000's | 14 (42.42) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirasawa, H; Matsuda, K; Nakanishi, K; Oda, S; Shiga, H; Ueno, H | 1 |
| Biffl, WL; Carnaggio, R; Ciesla, DJ; Johnson, JL; Moore, EE; Silliman, CC | 1 |
| Bai, L; Bian, GY; Hao, J; Lei, M; Sun, CJ; Zhang, P; Zhang, Y | 1 |
| Shabanov, VV | 1 |
| Kraft, M; Lerch, MM; Mayerle, J; Meister, T; Simon, P | 1 |
| Kirkpatrick, CJ; Klinge, U; Klosterhalfen, B; Mittermayer, C; Schumpelick, V; Töns, C | 1 |
| Fujita, K; Kaido, T; Kasamatsu, T; Kohmoto, M; Tamura, J; Tanaka, J; Yoshida, M | 1 |
| Mariscalco, MM | 1 |
| Kambayashi, J; Kawasaki, T; Mori, T; Ou, MC; Sakon, M; Shiba, E; Shinozaki, K; Uemura, Y; Yukawa, M | 1 |
| Cerra, FB; Cipolle, MD; Pasquale, MD | 1 |
| Biffl, WL; Moore, EE | 1 |
| Gennis, P; Katz, DP; Kvetan, V; Pastores, SM; Thakkar, A | 1 |
| Botha, AJ; Goode, AW; Moore, EE; Moore, FA; Peterson, VM; Silliman, CC | 1 |
| Barnett, CC; Moore, EE; Moore, FA; Partrick, DA; Silliman, CC | 1 |
| Manji, M; Neoptolemos, JP; Wilson, PG | 1 |
| Johnson, JL; Moore, EE; Offner, PJ; Partrick, DA; Silliman, CC; Tamura, DY | 1 |
| Denizot, Y; Feiss, P; Nathan, N | 1 |
| Barnett, CC; Fullerton, DA; Meldrum, DR; Moore, EE; Partrick, DA; Silliman, CC | 1 |
| Bakker, J; Curtis, L; Spapen, H; Vincent, JL; Webster, NR | 1 |
| Cheung, LY; Childs, EW; Smalley, DM | 1 |
| Goshima, M; Hori, Y; Kuroda, Y; Takase, K; Takeyama, Y; Ueda, T | 1 |
| Buurman, WA; Froon, AH; Greve, JW; Poeze, M; Ramsay, G | 1 |
| Curtis, LD; Imrie, CW; Johnson, CD; Kingsnorth, AN; Larvin, M; Leeder, PC; McKay, C; McMahon, MJ; Neoptolemos, JP; Skaife, P; Toh, SK; Wilson, P | 1 |
| Ulrich, CD | 1 |
| Aiboshi, J; Ciesla, DJ; Moore, EE; Silliman, CC | 1 |
| Camussi, G; Guida, G; Mariano, F; Tetta, C; Triolo, G | 1 |
| Kistler, EB; Mitsuoka, H; Schmid-Schönbein, GW | 1 |
| Heuer, HO | 1 |
| Anderson, BO; Bensard, DD; Harken, AH | 1 |
| Basha, MA; Kasahara, K; Kunkel, SL; Lynch, JP; Standiford, TJ; Strieter, RM | 1 |
| Anderson, BO; Harken, AH | 1 |
| Charbonneau, P; Suisse, A | 1 |
| Lefer, AM | 1 |
12 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and MODS
| Article | Year |
|---|---|
[Conservative treatment of acute pancreatitis].
Topics: Acute Disease; Adjuvants, Immunologic; Analgesics; Animals; Anti-Bacterial Agents; APACHE; C-Reactive Protein; Cholangiography; Cholangiopancreatography, Endoscopic Retrograde; Clinical Trials as Topic; Disease Models, Animal; Double-Blind Method; Enteral Nutrition; Humans; Imidazoles; Leucine; Multicenter Studies as Topic; Multiple Organ Failure; Pancreatitis; Pancreatitis, Acute Necrotizing; Placebos; Platelet Activating Factor; Prognosis; Protease Inhibitors; Randomized Controlled Trials as Topic; Retrospective Studies; Tomography, X-Ray Computed | 2003 |
Secondary organ dysfunction. From clinical perspectives to molecular mediators.
Topics: Antibodies, Monoclonal; Critical Care; Cytokines; Eicosanoids; Energy Metabolism; Humans; Inflammation; Multiple Organ Failure; Nitric Oxide; Platelet Activating Factor; Reactive Oxygen Species; Resuscitation; Risk Factors; Severity of Illness Index; Survival Rate | 1993 |
Splanchnic ischaemia/reperfusion and multiple organ failure.
Topics: Animals; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Rats; Reperfusion Injury; Splanchnic Circulation | 1996 |
Posttraumatic multiple-organ dysfunction syndrome: role of mediators in systemic inflammation and subsequent organ failure.
Topics: Animals; Cytokines; Eicosanoids; Humans; Inflammation Mediators; Multiple Organ Failure; Multiple Trauma; Nitric Oxide; Platelet Activating Factor; Reactive Oxygen Species; Resuscitation; Risk Factors; Survival Rate; Systemic Inflammatory Response Syndrome | 1996 |
Acute pancreatitis as a model of sepsis.
Topics: Acute Disease; Cytokines; Endotoxins; Humans; Multiple Organ Failure; Pancreatitis; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Sepsis; Systemic Inflammatory Response Syndrome; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Lexipafant in severe acute pancreatitis: the final word?
Topics: Animals; Clinical Trials as Topic; Humans; Imidazoles; Leucine; Multiple Organ Failure; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Severity of Illness Index | 2001 |
Involvement of platelet-activating factor (PAF) in septic shock and priming as indicated by the effect of hetrazepinoic PAF antagonists.
Topics: Animals; Azepines; Endotoxins; Humans; Models, Biological; Multiple Organ Failure; Platelet Activating Factor; Shock, Septic; Triazoles | 1991 |
The role of platelet activating factor and its antagonists in shock, sepsis and multiple organ failure.
Topics: Animals; Chemotaxis, Leukocyte; Humans; Kidney; Multiple Organ Failure; Myocardial Reperfusion Injury; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic | 1991 |
Host responses in mediating sepsis and adult respiratory distress syndrome.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Coagulation; Complement System Proteins; Cross Infection; Cytokines; Endopeptidases; Humans; Intensive Care Units; Lipopolysaccharides; Liver; Multiple Organ Failure; Platelet Activating Factor; Pneumonia; Respiratory Distress Syndrome | 1990 |
Multiple organ failure: inflammatory priming and activation sequences promote autologous tissue injury.
Topics: Animals; Endotoxins; Humans; Inflammation; Lung; Multiple Organ Failure; Neutrophils; Peroxidase; Platelet Activating Factor; Respiratory Distress Syndrome | 1990 |
[Syndrome of multiple organ failure].
Topics: Antibodies, Monoclonal; Eicosanoids; Humans; Interleukin-1; Monitoring, Physiologic; Multiple Organ Failure; Oxygen Consumption; Platelet Activating Factor; Syndrome; Tumor Necrosis Factor-alpha | 1990 |
Induction of tissue injury and altered cardiovascular performance by platelet-activating factor: relevance to multiple systems organ failure.
Topics: Animals; Capillary Permeability; Cardiovascular System; Heart; Hemodynamics; Humans; Multiple Organ Failure; Platelet Activating Factor; Shock; Vascular Resistance | 1989 |
3 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and MODS
| Article | Year |
|---|---|
Phase II multicenter clinical study of the platelet-activating factor receptor antagonist BB-882 in the treatment of sepsis.
Topics: Adult; Aged; Aged, 80 and over; APACHE; Cytokines; Double-Blind Method; Europe; Female; Hemodynamics; Humans; Immunotherapy; Infusions, Intravenous; Lactic Acid; Leucine; Male; Middle Aged; Multiple Organ Failure; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Function Tests; Sepsis; Survival Analysis | 2000 |
Decreased organ failure in patients with severe SIRS and septic shock treated with the platelet-activating factor antagonist TCV-309: a prospective, multicenter, double-blind, randomized phase II trial. TCV-309 Septic Shock Study Group.
Topics: Adult; Aged; APACHE; Double-Blind Method; Female; Humans; Inflammation Mediators; Isoquinolines; Male; Middle Aged; Multiple Organ Failure; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prospective Studies; Pyridinium Compounds; Shock, Septic; Systemic Inflammatory Response Syndrome; Tetrahydroisoquinolines | 2000 |
Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis.
Topics: Acute Disease; Adult; Aged; Biomarkers; Double-Blind Method; E-Selectin; Female; Humans; Imidazoles; Interleukin-8; Length of Stay; Leucine; Logistic Models; Male; Middle Aged; Multiple Organ Failure; Pancreatitis; Placebos; Platelet Activating Factor; Prospective Studies | 2001 |
18 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and MODS
| Article | Year |
|---|---|
Coagulation/fibrinolysis abnormality and vascular endothelial damage in the pathogenesis of thrombocytopenic multiple organ failure.
Topics: Adult; Aged; Blood Coagulation; Endothelium, Vascular; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Humans; Interleukin-6; Leukocyte Elastase; Male; Middle Aged; Multiple Organ Failure; Platelet Activating Factor; Platelet Count; Retrospective Studies; Sepsis; Thrombocytopenia; Thrombomodulin | 2002 |
Clinically relevant hypertonicity prevents stored blood- and lipid-mediated delayed neutrophil apoptosis independent of p38 MAPK or caspase-3 activation.
Topics: Apoptosis; Blood Preservation; Caspase 3; Caspase Inhibitors; Caspases; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; In Vitro Techniques; Lysophosphatidylcholines; Mitogen-Activated Protein Kinases; Multiple Organ Failure; Neutrophils; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Pyridines; Saline Solution, Hypertonic | 2003 |
[Dynamic changes of platelet number in early multiple injury and it is effect on prognosis].
Topics: Adolescent; Adult; Aged; Blood Platelets; Child; Female; Humans; Male; Middle Aged; Multiple Organ Failure; Multiple Trauma; Platelet Activating Factor; Platelet Count; Prognosis | 2003 |
[Cytokines and other signal molecules in the pathogenesis of acute pancreatitis].
Topics: Acute Disease; Acute-Phase Proteins; Animals; Cell Adhesion Molecules; Chemokines; Cytokines; Free Radicals; Humans; Imidazoles; Interleukins; Leucine; Mice; Multiple Organ Failure; Pancreas; Pancreatitis; Platelet Activating Factor; Rabbits; Rats; Selectins; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha | 2003 |
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Critical Care; Epoprostenol; Escherichia coli Infections; Hemodynamics; Interleukin-6; Intestinal Mucosa; Intestines; Ion Channels; Ischemia; Lung; Microscopy, Electron; Multiple Organ Failure; Platelet Activating Factor; Postoperative Complications; Potassium; Pulmonary Gas Exchange; Respiratory Distress Syndrome; Shock, Septic; Swine; Thromboxane A2; Tumor Necrosis Factor-alpha | 1993 |
Significance of altered fluidity of plasma membranes of the liver and kidney in rats with sepsis.
Topics: Animals; Fluorescence Polarization; Kidney; Lipopolysaccharides; Liver; Male; Membrane Fluidity; Multiple Organ Failure; Platelet Activating Factor; Rats; Rats, Wistar; Sepsis | 1995 |
Leukocytes and the inflammatory response.
Topics: Adhesiveness; Age Factors; Animals; Antibodies, Monoclonal; Antigens, CD; CD11 Antigens; CD18 Antigens; Cell Adhesion Molecules; Cell Movement; Disease Models, Animal; Endothelium; Humans; Infant, Newborn; Inflammation; Interleukin-8; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Receptors, Leukocyte-Adhesion; Reperfusion Injury; Respiratory Distress Syndrome | 1993 |
Potential etiologic role of PAF in two major septic complications; disseminated intravascular coagulation and multiple organ failure.
Topics: Alanine Transaminase; Animals; Bacterial Infections; Blood Cell Count; Blood Urea Nitrogen; Cholangitis; Common Bile Duct; Disseminated Intravascular Coagulation; Endotoxins; Fibrinogen; Hematocrit; Liver; Male; Multiple Organ Failure; Partial Thromboplastin Time; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Rabbits | 1994 |
Sequential systemic platelet-activating factor and interleukin 8 primes neutrophils in patients with trauma at risk of multiple organ failure.
Topics: Adolescent; Adult; Aged; Female; Humans; Injury Severity Score; Interleukin-8; Male; Middle Aged; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Time Factors; Wounds and Injuries | 1996 |
Lipid mediators up-regulate CD11b and prime for concordant superoxide and elastase release in human neutrophils.
Topics: Humans; Inflammation; Leukocyte Elastase; Leukotriene B4; Macrophage-1 Antigen; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Respiratory Burst; Superoxides; Wounds and Injuries | 1997 |
Hypertonic saline activates lipid-primed human neutrophils for enhanced elastase release.
Topics: Humans; Leukotriene B4; Multiple Organ Failure; Multiple Trauma; Neutrophil Activation; Neutrophils; Osmolar Concentration; Pancreatic Elastase; Platelet Activating Factor; Resuscitation; Saline Solution, Hypertonic; Superoxides | 1998 |
Are lipid mediators implicated in the production of pro- and anti-inflammatory cytokines during cardiopulmonary bypass graft with extracorporeal circulation?
Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents; Cardiopulmonary Bypass; Cytokines; Dinoprostone; Extracorporeal Circulation; Humans; Inflammation Mediators; Interleukin-10; Interleukin-4; Interleukin-6; Interleukin-8; Leukotriene B4; Leukotriene C4; Lipid Metabolism; Lipids; Multiple Organ Failure; Platelet Activating Factor; Prospective Studies; Thromboxane B2; Tumor Necrosis Factor-alpha | 1999 |
Cardiopulmonary bypass renders patients at risk for multiple organ failure via early neutrophil priming and late neutrophil disability.
Topics: Adolescent; Adult; Aged; Cardiopulmonary Bypass; Female; Humans; Male; Middle Aged; Multiple Organ Failure; NADPH Oxidases; Neutrophils; Pancreatic Elastase; Platelet Activating Factor; Reactive Oxygen Species; Risk Factors; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
The local effect of PAF on leukocyte adherence to small bowel mesenteric venules following intra-abdominal contamination.
Topics: Animals; Cell Adhesion; Feces; Intestinal Perforation; Intestine, Small; Leukocytes; Male; Mesenteric Veins; Microcirculation; Multiple Organ Failure; Neutrophil Infiltration; Peritonitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Venules | 2000 |
Pancreatitis-associated ascitic fluid increases intracellular Ca(2+) concentration on hepatocytes.
Topics: Acute Disease; Animals; Ascitic Fluid; Calcium; Cells, Cultured; Dogs; Egtazic Acid; Liver; Male; Multiple Organ Failure; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Verapamil | 2000 |
Blood transfusion and the two-insult model of post-injury multiple organ failure.
Topics: Blood Preservation; Cell Adhesion; Cells, Cultured; Chemotaxis, Leukocyte; Drug Synergism; Endothelium, Vascular; Fibrinogen; Humans; Inflammation; Lysophosphatidylcholines; Models, Biological; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidative Stress; Platelet Activating Factor; Risk; Superoxides; Transfusion Reaction | 2001 |
Hemofiltration reduces the serum priming activity on neutrophil chemiluminescence in septic patients.
Topics: Acute Kidney Injury; Aged; Blood Physiological Phenomena; Hemofiltration; Humans; Interleukin-8; Luminescent Measurements; Middle Aged; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Reference Values; Respiratory Burst; Shock, Septic; Uremia | 2001 |
Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock.
Topics: Animals; Blood Pressure; Endopeptidases; Esters; Gabexate; Guanidines; Humans; In Vitro Techniques; Inflammation; Intestinal Mucosa; Intestines; Leukocytes; Male; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phospholipases A; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion; Serine Endopeptidases; Serine Proteinase Inhibitors; Shock; Splanchnic Circulation; Survival Rate | 2002 |