1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with Innate Inflammatory Response in 410 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 103 (25.12) | 18.7374 |
| 1990's | 150 (36.59) | 18.2507 |
| 2000's | 89 (21.71) | 29.6817 |
| 2010's | 50 (12.20) | 24.3611 |
| 2020's | 18 (4.39) | 2.80 |
| Authors | Studies |
|---|---|
| Abohassan, M; Al Shahrani, M; Alshahrani, MY; Begum, N; Radhakrishnan, S; Rajagopalan, P | 1 |
| English, CJ; Lohning, AE; Mayr, HL; Reidlinger, DP | 1 |
| Dalli, J; Gomez, EA; Jouvene, CC | 1 |
| Sharif, NA | 1 |
| Grunebaum, E; Sussman, G; Upton, JEM; Vadas, P | 1 |
| Ito, H; Kanzaki, K; Kawakami, Y; Maruoka, S; Miki, Y; Mori, Y; Murakami, M; Nagasaki, Y; Okamoto, K; Sawazumi, R; Suzuki-Yamamoto, T; Takahashi, Y; Tamenobu, A; Toda, K; Tsukayama, I; Yamamoto, K | 1 |
| Alves, NG; Boric, M; Breslin, JW; Burboa, PC; Durán, RG; Durán, WN; Golenhofen, N; Iwahashi, T; Kim, DD; Lillo, MA; Mujica, PE; Nepali, PR; Sánchez, FA; Thomas, AP; Zhang, J | 1 |
| Airoldi, C; Basello, K; Cappelletti, M; Ciliberti, A; Costanzi, A; Dessì, DA; Familiari, A; Lanzone, A; Neri, C; Speciani, AF; Tersigni, C | 1 |
| Belio, Ú; Carrera-Lasfuentes, P; de la Rosa, X; Domper-Arnal, MJ; Hawkins, M; Higuera, GA; Irún, P; Lanas, A; Sánchez-Luengo, M | 1 |
| Brown, L; Panchal, SK | 1 |
| Huard, A; Khey, KMW; Mahmoud, SH | 1 |
| Arifulin, EA; Azbukina, NV; Baksheeva, VE; Chistyakov, DV; Chistyakov, VV; Gancharova, OS; Goriainov, SV; Komarov, SV; Philippov, PP; Senin, II; Sergeeva, MG; Tikhomirova, NK; Tiulina, VV; Zamyatnin, AA; Zernii, EY | 1 |
| Chen, H; Pang, C; Xiao, X; Xu, C; Zhang, M; Zhu, W; Zhuang, X | 1 |
| Abraham, SN; Bergmeier, W; Boulaftali, Y; Choi, HW; Karhausen, J; Lee, RH; Ma, Q; Maddipati, KR; Mathew, JP | 1 |
| Chaithra, VH; Chen, CH; Ke, LY; Marathe, GK | 1 |
| Antonopoulou, S; Demopoulos, CA; Theoharides, TC | 1 |
| Cheng, Q; Du, Y; Wu, H | 1 |
| Antonopoulou, S; Demopoulos, C; Theoharides, TC | 1 |
| Bauer, JM; Bernhard, S; Erber, M; Fauler, M; Föhr, KJ; Hoffmann, A; Huber-Lang, M; Hug, S; Knapp, CL; Messerer, DAC; Radermacher, P; Stratmann, AEP; Vidoni, L; Wohlgemuth, L | 1 |
| Fauland, A; Gabrielsson, S; Larssen, P; Lukic, A; Radmark, O; Samuelsson, B; Wheelock, CE | 1 |
| Dumas, E; Lavoie, SS; Neagoe, PE; Sirois, MG; Vulesevic, B; White, M | 1 |
| Lordan, R; Tsoupras, A; Zabetakis, I | 1 |
| Anthony, DC; Barteneva, NS; Dukhinova, M; Kopeikina, E; Kuznetsova, I; Levchuk, K; Liu, JYH; Ponomarev, ED; Rudd, J; Strekalova, T; Veniaminova, E; Veremeyko, T; Wing-Ho, KK; Yau, SSY; Yung, AWY; Yung, WH | 1 |
| He, S; Mo, YZ; Wei, JF; Wei, XL; Yang, H | 1 |
| Cai, SQ; Chen, HB; Shang, MY; Wang, RF; Wang, TM | 1 |
| Bennett, SA; Fai, S; Herrmann, N; Lanctôt, KL; Mazereeuw, G; Swardfager, W; Valenzuela, N; Xu, H | 1 |
| Chen, K; Xia, SH; Xiang, XH; Xu, W | 1 |
| Bellanti, F; Giudetti, AM; Serviddio, G; Siculella, L; Stanca, E; Vendemiale, G | 1 |
| Eidem, LE; Feuerherm, AJ; Johansen, B; Jørgensen, KM; Lægreid, A; Sommerfelt, RM | 1 |
| Danker, K; Hildmann, A; Klein, A; Lucka, L; Schön, M; Schön, MP; Semini, G; Shmanai, V | 1 |
| Bessi, VL; Bitencourt, CS; Borgeat, P; Faccioli, LH; Hamdan, L; Huynh, DN; Lefebvre, JS; Lévesque, T; Marleau, S; Ménard, L; Sohouhenou, F | 1 |
| Morimoto, R; Shimizu, T; Shindou, H; Tarui, M | 1 |
| Montagni, M; Parente, R; Ridolo, E; Triggiani, M | 1 |
| Berbée, JF; Habets, KL; Havekes, LM; Kooijman, S; Korporaal, SJ; Lammers, B; Meurs, I; Rensen, PC; Romijn, JA; van der Stoep, M; van Eck, M | 1 |
| Abdulnour, RE; Colas, RA; Colby, JK; Dalli, J; Krishnamoorthy, N; Levy, BD; Petasis, NA; Serhan, CN; Tan, SH; Timmons, JY | 1 |
| Higa, R; Ikari, A; Ishii, S; Matsui, M; Miwa, M; Miyake, M; Shimizu, T; Sugatani, J; Yamaguchi, M; Yamazaki, Y | 1 |
| Cai, J; Feng, SQ; Gao, Z; Gozal, D; Liu, Y; Shields, CB; Shields, LBE; Wang, Y; Zhang, Y; Zhao, YZ; Zhu, Q | 1 |
| Ebina, K; Sato, A; Yokoyama, I | 1 |
| Piuri, G; Speciani, AF | 1 |
| Aquino, EN; Castro, MS; Correa, JR; Fontes, W; Neves, AC; Santos, KC; Souza, PE; Uribe, CE | 1 |
| Damiani, E; Ullrich, SE | 1 |
| Andolina, G; Calado, Â; Faggio, C; Saldanha, C; Silva-Herdade, AS | 1 |
| Filgueiras, LR; Ishizuka, EK; Jancar, S; Rios, FJ; Serezani, CH | 1 |
| Cai, J; Chu, T; Gao, Z; Liu, Y; Shields, CB; Shields, LBE; Wang, Y; Zhang, YP; Zhu, Q | 1 |
| Al-Hassani, M; Cai, S; Hingtgen, CM; Pollok, KE; Sitzman, LA; Travers, JB; Zhang, Q | 1 |
| Behnk, A; Günther, A; Hecker, M; Mayer, K; Ott, J; Pose, A; Schaefer, MB; Schulz, R; Seeger, W; Weissmann, N | 1 |
| Durán, RG; Durán, WN; Kim, DD; Meininger, CJ; Sánchez, FA | 1 |
| McIntyre, TM; Prescott, SM; Stafforini, DM | 1 |
| Chen, H; Cui, Y; Ding, W; Dong, C; Ezoulin, JM; Heymans, F; Hu, J; Li, J; Shao, B; Zhou, W; Zhu, X | 1 |
| Bar-Eli, M; Melnikova, VO | 1 |
| Chang, W; Chen, J; Hoyle, GW; Schlueter, CF | 1 |
| Cripps, MW; Cureton, EL; Curran, B; Dua, MM; Ereso, AQ; Sadjadi, J; Victorino, GP | 1 |
| Hakim-Rad, K; Maurer, M; Metz, M | 1 |
| Constantinescu, CS; Edwards, LJ | 1 |
| Camerer, E; Cornelissen, I; Coughlin, SR; Duong, DN; Palmer, D; Pappu, R; Pham, TH; Regard, JB; Srinivasan, Y; Wong, JS | 1 |
| Bazan, HE; Kenchegowda, S | 1 |
| Berge, RK; Felberg, HS; Johansen, B; Jørgensen, KM; Laegreid, A | 1 |
| Weyrich, AS; Yost, CC; Zimmerman, GA | 1 |
| Ritter, JM | 1 |
| Baccei, CS; Bain, G; Broadhead, AR; Chapman, C; Correa, LD; Darlington, JV; Evans, JF; Hutchinson, JH; King, CD; Lee, C; Lorrain, DS; Prasit, P; Prodanovich, PP; Roppe, J; Santini, AM; Stearns, B; Stock, NS; Zunic, J | 1 |
| Adamson, RH; Altangerel, A; Clark, JF; Curry, FR; Sarai, RK; Thirkill, TL | 1 |
| Asaka, N; Kakuo, H; Kiniwa, M; Ohmori, K; Oka, T; Sasaki, E; Togawa, M; Yamada, S | 1 |
| Liu, SH; Ma, K; Xu, B; Xu, XR | 1 |
| Faxvaag, A; Feuerherm, AJ; Johansen, B; Leistad, L | 1 |
| Beaugie, C; Byrne, SN; Halliday, GM; Leighton, S; O'Sullivan, C | 1 |
| Beuve, AV; Durán, RG; Durán, WN; Fulton, DJ; González, FG; Iwahashi, T; Kim, DD; Rana, R; Sánchez, FA | 1 |
| Altomare, A; Behar, J; Biancani, P; Cao, W; Cicala, M; Guarino, MP; Harnett, KM; Ma, J; Orlando, RC; Paterson, WG | 1 |
| Marentette, JO; McHowat, J; Rastogi, P; Sharma, J; Turk, J; Young, DM | 1 |
| Janakiram, NB; Mohammed, A; Rao, CV | 1 |
| Bieberbach, EWR; Fernandes, LC; Kryczyk, M; Michelotto, PV; Muehlmann, LA; Nishiyama, A; Zanatta, AL | 1 |
| DaSilva, SC; Konger, RL; Kozman, AA; Martel, KC; Rezania, S; Sahu, RP; Travers, JB; Warren, SJ; Yao, Y | 1 |
| Dona, M; Fredman, G; Irimia, D; Krishnamoorthy, S; Oh, SF; Serhan, CN | 1 |
| Aoki, J; Ebina, K; Kumagai, T; Sato, A | 1 |
| He, P; Yuan, D | 1 |
| Koutsilieris, M; Mavragani, CP; Moschos, MM; Nitoda, E | 1 |
| Lambeau, G; Murakami, M | 1 |
| Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Pinto, LG; Verri, WA; Vieira, SM; Zaperlon, AC; Zarpelon, AC | 1 |
| Berman, B; Cockerell, CJ | 1 |
| Argenziano, M; Besana, A; Comas, GM; Danilo, P; Feinmark, SJ; Harleton, E; Robinson, RB; Rosen, MR; Rosen, TS | 1 |
| Ebina, K; Sato, A | 1 |
| Prescott, SM; Weyrich, AS; Zimmerman, GA | 1 |
| Magnusson, JE; Teather, LA; Wurtman, RJ | 1 |
| Gute, DC; Ishida, S; Korthuis, RJ; Shigematsu, S | 1 |
| Kulikov, VI; Muzya, GI | 1 |
| Bussolati, B; Camussi, G; Mantovani, A; Peri, G; Salvidio, G; Verzola, D | 1 |
| Benjamim, CF; Cunha, Fde Q; Ferreira, SH; Rios-Santos, F; Zavery, D | 1 |
| John Chapman, M; Tselepis, AD | 1 |
| Hara, M; Ishida, S; Korthuis, RJ; Sakata, T; Shigematsu, S; Takahashi, N; Yoshimatsu, H | 1 |
| Harrison, KA; Marathe, GK; McIntyre, TM; Murphy, RC; Neilsen, PO; Watanabe, J; Weyrich, AS; Zimmerman, GA | 1 |
| Bar-Or, D; Curtis, CG; Rael, LT; Shimonkevitz, RP; Thomas, GW; Winkler, JV; Yukl, RL | 1 |
| Calabresi, L; Franceschini, G; Gomaraschi, M | 1 |
| Chien, EK; Elovitz, MA; Phillippe, M; Rychlik, DF; Wang, Z | 1 |
| Galani, V; Lekka, ME; Liokatis, S; Nakos, G; Nathanail, C | 1 |
| McIntyre, TM; Prescott, SM; Stafforini, DM; Zimmerman, GA | 2 |
| Barnes, PJ | 6 |
| Bancalari, E; Huang, J; Rodriguez, MM; Smalling, WE; Suguihara, C | 1 |
| Andrade, SP; Barcelos, LS; Campos, PP; Ferreira, MA; Teixeira, MM; Vasconcelos, AC | 1 |
| Balestrieri, C; Balestrieri, ML; De Prisco, R; Iorio, EL; Moriello, VS; Nicolaus, B; Pari, P; Servillo, L; Strazzullo, G | 1 |
| Chan, JS; Filep, JG; József, L; Khreiss, T | 1 |
| De Plaen, IG; Han, XB; Hsueh, W; Liu, X | 1 |
| Brown, GE; Cherepanov, V; Degousee, N; Downey, GP; Gelb, MH; Ghomashchi, F; Glogauer, M; Grinstein, S; Harkin, DW; Kelvin, D; Koh, A; Lindsay, TF; Nallan, L; Plumb, J; Rubin, BB; Sadilek, M; Smart, BP; Stefanski, E; Sun, C; Vachon, E; Yaffe, MB | 1 |
| Favier, J; Lemieux, C; Maliba, R; Merhi, Y; Sirois, MG; Théorêt, JF | 1 |
| Bulger, E; Cuschieri, J; Garcia, I; Jelacic, S; Maier, RV | 1 |
| Fukuda, S; Greener, Y; Jablonski, E; Killam, AL; Schmid-Schönbein, GW; Suematsu, M; Tojo, SJ; Yasu, T | 1 |
| Behar, J; Biancani, P; Cao, W; Cheng, L; Fiocchi, C; Harnett, KM | 1 |
| Castro Faria Neto, HC; Prescott, SM; Stafforini, DM; Zimmerman, GA | 1 |
| Azuma, J; Fujio, Y; Maeda, M; Matsuda, T; Nariai, T; Sumita, C; Yamane, M | 1 |
| Chen, XH; Liao, WH; Ou-Yang, XY; Wang, WJ | 1 |
| Billings, SD; Johnson, C; Marathe, GK; McIntyre, TM; Murphy, RC; Pei, Y; Southall, MD; Spandau, D; Travers, JB; Zimmerman, GA | 1 |
| Antonopoulou, S; Athanasopoulos, S; Fragopoulou, E; Milias, GA; Nomikos, T | 1 |
| Choi, IW; Im, SY; Kim, JH; Kim, YS; Ko, HM; Lee, HK; Lee, JH; Lee, YC; Park, YM; You, HJ | 1 |
| Al-Hassani, M; Billings, SD; Howard, KM; Ishii, S; Mousdicas, N; Perkins, SM; Shimizu, T; Travers, JB; Yi, Q; Zhang, Q | 1 |
| Granger, J; Remick, D | 1 |
| Doi, K; Fujita, T; Ishii, S; Kihara, Y; Kita, Y; Nakao, A; Negishi, K; Noiri, E; Okamoto, K; Shimizu, T; Suzuki, Y; Toda, A; Yokomizo, T | 1 |
| Denizot, Y; Descottes, B; Labrousse, F; Mathonnet, M; Truffinet, V; Valleix, D | 1 |
| Karabina, SA; Ninio, E | 1 |
| Kurnatowska, A; Lewkowicz, N; Lewkowicz, P; Tchórzewski, H | 1 |
| Calixto, JB; Kassuya, CA; Marotta, DM; Menezes-de-Lima, O; Rehder, VL; Silvestre, A | 1 |
| Ananthaswamy, HN; Bucana, C; Byrne, S; Matsumura, Y; Nghiem, DX; Ullrich, SE; Walterscheid, JP; Wolf, P | 1 |
| Byrne, SN; Matsumura, Y; Miyahara, Y; Nghiem, DX; Ullrich, SE | 1 |
| Harayama, T; Hishikawa, D; Ishii, S; Nakanishi, H; Shimizu, T; Shindou, H; Taguchi, R | 1 |
| Bown, MJ; London, NJ; Sandford, RM; Sayers, RD | 1 |
| Clandinin, MT; Ma, DW; Park, EJ; Ramanujam, K; Suh, M; Thomson, AB; Thomson, B | 1 |
| Collot-Teixeira, S; Martin, J; McGregor, JL; McGregor, L | 1 |
| Andrade, SP; Bakhle, YS; Barcelos, LS; Ferreira, MA; Teixeira, MM | 1 |
| Bar-Eli, M; Melnikova, V | 1 |
| Chen, MF; Ding, WL; Gu, HY; Hu, JJ; Liu, WC | 1 |
| Harayama, T; Ogasawara, R; Shimizu, T; Shindou, H; Suwabe, A | 1 |
| Fukunaga, A; Khaskhely, NM; Khaskina, P; Sreevidya, CS; Ullrich, SE | 1 |
| Colditz, IG; Movat, HZ | 2 |
| Benveniste, J; Mencia-Huerta, JM; Roubin, R | 1 |
| O'Flaherty, JT | 2 |
| Pinckard, RN | 1 |
| Bach, MK | 1 |
| Bohn, A; Borgeat, P; Bremm, KD; Brom, HJ; Crea, AE; Falsone, G; König, W; Pison, U; Spur, B; Theobald, K | 1 |
| Vargaftig, BB | 1 |
| Goetzl, EJ; Kaplan, AP | 1 |
| Kalter, ES | 1 |
| Satouchi, K | 1 |
| Weksler, BB | 1 |
| O'Flaherty, JT; Wykle, RL | 1 |
| Issekutz, AC | 1 |
| Hechtman, HB; Shepro, D; Valeri, CR | 1 |
| Henson, PM; Larsen, GL | 1 |
| Bult, H; Herman, AG | 1 |
| Gunby, P | 1 |
| Huston, L; Leid, RW; Liggitt, HD | 1 |
| Barth, T; Bekemeier, H; Hänsel, F; Hirschelmann, R; Sänze, JU | 1 |
| Basran, GS; Dewar, A; Morley, J; Page, CP; Paul, W; Wood, L | 1 |
| Morley, J; Page, CP; Paul, W | 1 |
| Myśliwiec, B; Myśliwiec, M | 1 |
| Miller, CL | 1 |
| Henson, PM | 2 |
| Arnoux, B; Benveniste, J; Durand, J; Rigaud, M; Vargaftig, BB | 1 |
| Czarneztki, BM | 1 |
| Betz, SJ; Henson, PM | 1 |
| Clark, PO; Demopoulos, CA; Halonen, M; Hanahan, DJ; Kniker, WT; McManus, LM; Pinckard, RN; Shaw, JO | 1 |
| Gimbrone, MA | 1 |
| Benveniste, J; Chignard, M; Lefort, J; Vargaftig, BB | 1 |
| Bessin, P; Bonnet, J; Loiseau, AM; Orvoen, M | 1 |
| Kanwar, S; Kubes, P | 1 |
| Martin, JG | 1 |
| Banerjee, A; Botha, AJ; Kim, FJ; Moore, EE; Moore, FA; Peterson, VM | 1 |
| Levi-Schaffer, F; Slavin, S; Vourka-Karussis, U | 1 |
| Collins, PD; Connolly, DT; Williams, TJ | 1 |
| Lorant, DE; McEver, RP; McIntyre, TM; Prescott, SM; Topham, MK; Whatley, RE; Zimmerman, GA | 1 |
| Fan, TP; Gresham, GA; Guard, S; Hu, DE; Watling, KJ | 1 |
| Bazan, NG | 1 |
| Das, A; Larkin, SW; Nourshargh, S; Williams, TJ | 1 |
| Chen, XS; Funk, CD; Griffis, G; Kurre, U | 1 |
| Guinot, P | 1 |
| Bonavida, B; Mencia-Huerta, JM | 1 |
| Green, PG; Jänig, W; Levine, JD; Miao, FJ | 1 |
| Coffman, TM; Goulet, JL; Koller, BH; Latour, AM; Snouwaert, JN | 1 |
| Gardner, CR; Laskin, DL; Laskin, JD | 1 |
| Belogi, L; Cavallo, G; Cifone, MG; Croce, C; Guida, G; Mainiero, F; Santiangeli, C; Santoni, A; Tubaro, E | 1 |
| Crissinger, KD | 1 |
| Fairbairn, SM; Hellewell, PG; Norman, KE; Rossi, AG; Teixeira, MM; Williams, TJ | 1 |
| Battram, CH; Jordan, R; Lewis, SA; Raeburn, D; Sharma, S; Souness, JE; Tomkinson, A; Underwood, SL; Webber, SE; Woodman, VR | 1 |
| Abe, T; Matsuda, K; Nagai, H; Omata, T; Segawa, Y; Yoshida, K | 1 |
| Benoit, JN; Granger, DN; Harris, NR | 1 |
| Chen, XS; Funk, CD; Johnson, EN; Sheller, JR | 1 |
| Caplan, MS; MacKendrick, W | 1 |
| Braquet, PG; Guinot, P; Hosford, D; Koltai, M | 1 |
| Bernard, GR; Christman, BW | 1 |
| De Clerck, F; Folkerts, G; Nijkamp, FP; Reijnart, I; Span, P | 1 |
| Mariscalco, MM | 1 |
| Bergmann, R; Gokel, M; Hammer, C; Saumweber, DM | 1 |
| Catania, A; Ceriani, G; Lipton, JM; Macaluso, A | 1 |
| Rothenberger, DA; Wiltz, O | 1 |
| Henderson, WR; Koenig, JQ; Luchtel, DL; McBride, DE; Williams, PV | 1 |
| Barbier, A; Boisseau, MR; Braquet, P; Carpentier, P; Clostre, F; Ladure, P; Taccoen, A | 1 |
| Akutagawa, H; Mayumi, M; Mikawa, H; Morita, M; Nambu, M; Ohshima, Y; Uenoyama, Y | 1 |
| Green, PG; Heller, PH; Levine, JD; Luo, J | 1 |
| Ino, M; Miwa, M; Mizoguchi, K; Nakamura, S; Okamoto, G; Okamoto, Y; Sugatani, J; Suzuki, Y; Yoshida, H | 1 |
| Schleimer, RP | 1 |
| Bozza, PT; Castro Faria Neto, HC; Cordeiro, RS; e Silva, PM; Lima, MC; Martins, MA; Vargaftig, BB | 1 |
| Lobb, RR; Nourshargh, S; Weg, VB; Williams, TJ | 1 |
| Egido, J; Gómez-Guerrero, C; González, E; Hernando, P; Ruiz-Ortega, M | 1 |
| Bennett, SA; Birnboim, HC; Leite, LC | 1 |
| Johnston, FL; Kanwar, S; Kubes, P; Reinhardt, PH; Woodman, RC | 1 |
| Northover, AM | 2 |
| Cerra, FB; Cipolle, MD; Pasquale, MD | 1 |
| Alabaster, VA; Moore, BA | 1 |
| Feuerstein, G; Hallenbeck, JM; Liu, Y; Sirén, AL | 1 |
| Durán, WN; Fallek, SR; Hobson, RW; Noel, AA | 1 |
| Barnett, CC; Biffl, WL; Moore, EE; Moore, FA | 1 |
| Chapman, MJ; Dentan, C; Lesnik, P; Ninio, E | 1 |
| Nadel, JA | 1 |
| Bauer, J; Carlson, RP; Glaser, KB; Hartman, DA; Lock, YW; Sung, ML; Walter, T | 1 |
| Biffl, WL; Moore, EE | 1 |
| Kohno, S; Nabe, T; Yamamura, H | 1 |
| Allan, G; Bazan, NG | 1 |
| Ahluwalia, A; Flower, RJ; Harris, HJ; Harris, JG; Perretti, M; Wheller, SK | 1 |
| Calignano, A; Cozzolino, A; Mancuso, F; Metafora, S; Porta, R | 1 |
| Lin, CC; Lin, CY | 1 |
| Byrum, RS; Goulet, JL; Griffiths, RJ; Koller, BH | 1 |
| Boukedes, SS; Campbell, EJ; Campbell, MA; Owen, CA | 1 |
| Saito, K | 1 |
| Albert, DH; Carter, GW; Curtin, M; Davidsen, SK; Heyman, HR; Luo, G; Magoc, TJ; Morgan, DW; Sheppard, GS; Summers, JB; Tapang, P; Xu, L | 1 |
| FitzGerald, GA | 1 |
| El-Shazly, AE; Eura, M; Ishikawa, T; Masuyama, K | 1 |
| Gingras, D; Lacasse, C; Rola-Pleszczynski, M; Stankova, J; Turcotte, S | 1 |
| Chen, W; Li, S; Liu, B; Zhang, H | 1 |
| Bryant, AE; Bunting, M; Lorant, DE; McIntyre, TM; Prescott, SM; Stevens, DL; Zimmerman, GA | 1 |
| Gerritsen, ME; Granger, DN; Henninger, DD | 1 |
| Bjursten, LM; Schmid-Schönbein, GW; Tung, DK; Zweifach, BW | 1 |
| Barnett, CC; Moore, EE; Moore, FA; Partrick, DA; Silliman, CC | 1 |
| Oh-ishi, S | 1 |
| LeClerc, JL; Vincent, JL; Wan, S | 1 |
| Gonzalez-Crussi, F; Hsueh, W; Qu, XW; Sun, XM; Tan, XD | 1 |
| DeLano, FA; Forrest, MJ; Schmid-Schönbein, GW | 1 |
| Buades, J; Camussi, G; Mariano, F; Ronco, C; Tetta, C; Wratten, ML | 1 |
| Mantovani, A | 1 |
| Bratton, DL; Fadok, VA; Freed, PW; Henson, PM; Konowal, A; Westcott, JY | 1 |
| Erickson, KL | 1 |
| Nagai, A; Takeda, Y; Tamaoki, J; Yamawaki, I | 1 |
| Costa, JJ; Delano, FA; Harris, AG; Schmid-Schönbein, GW; Zweifach, BW | 1 |
| Heller, A; Koch, T; Schmeck, J; van Ackern, K | 1 |
| Barnathan, ES; Buck, CA; Cines, DB; Hug, BA; Konkle, BA; Loscalzo, J; McCrae, KR; McEver, RP; Pober, JS; Pollak, ES; Schmidt, AM; Schwartz, BS; Stern, DM; Wick, TM; Zimmerman, GA | 1 |
| Kitayama, J; Mackay, CR; Ponath, PD; Springer, TA | 1 |
| Kitsiouli, EI; Lekka, ME; Nakos, G; Tsangaris, I | 1 |
| Tuder, RM; Voelkel, NF | 1 |
| Goracci, G; Gresele, P; Guerra, M; Mezzasoma, AM; Ribaldi, E; Staffolani, N | 1 |
| Bochner, BS; Kurashige, T; Matsumoto, K; Wakiguchi, H | 1 |
| Hood, AF; Morin, SM; Pei, Y; Travers, J | 1 |
| Pace-Asciak, CR; Reynaud, D; Wang, MM | 1 |
| Barber, LA; Clay, KL; Hood, AF; Johnson, CA; Morelli, JG; Morin, SM; Murphy, RC; Pei, Y; Travers, JB; Williams, DA | 1 |
| Alonso, A; Bayón, Y; Hernández, M; Nieto, ML; Sánchez Crespo, M | 1 |
| McNulty, CA; Symon, FA; Wardlaw, AJ | 1 |
| Chistov, IV; Dugina, TN; Glusa, E; Pinelis, VG; Storozhevykh, TP; Strukova, SM; Umarova, BA | 1 |
| Calabrese, S; Delbello, C; Dobrina, A; Fiotti, N; Giansante, C; Guarnieri, G; Ponte, E; Zacchi, T | 1 |
| Ekiz, F; Fincan, K; Haklar, G; Köksoy, F; Soybir, G; Yalçin, O; Yüksel, M | 1 |
| Peplow, PV | 1 |
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| Di Virgilio, F; Dichmann, S; Ferrari, D; Hofmann, C; Idzko, M; Luttmann, W; Norgauer, J; Virchow, C; Zimpfer, U | 1 |
| Filler, SG; Orozco, AS; Zhou, X | 1 |
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| László, F; Morschl, E; Nemcsik, J; Pávó, I; Pozsár, J; Whittle, BJ | 1 |
| Harrison, KA; Marathe, GK; McIntyre, TM; Murphy, RC; Prescott, SM; Zimmerman, GA | 1 |
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| Harrison, KA; Marathe, GK; McIntyre, TM; Morrow, JD; Murphy, RC; Prescott, SM; Roberts, LJ; Tjoelker, LW; Zimmerman, GA | 1 |
| Aiboshi, J; Ciesla, DJ; Moore, EE; Silliman, CC | 1 |
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| de Castro Faria Neto, HC; Marathe, GK; McIntyre, TM; Prescott, SM; Silva, AR; Tjoelker, LW; Zimmerman, GA | 1 |
| Blaser, K; Simon, HU; Thomet, OA; Wiesmann, UN | 1 |
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| Bozza, MT; Bozza, PT; Caiado, LF; Castro-Faria-Neto, HC; de Assis, EF; Marathe, GK; McIntyre, TM; Prescott, SM; Silva, AR; Zimmerman, GA | 1 |
| Carlson, SL; Hostettler, ME; Knapp, PE | 1 |
| Cruzado, JM; Grinyó, JM; Herrero-Fresneda, I; Hurtado, I; Lloberas, N; Riera, M; Torras, J | 1 |
| Akasawa, A; Iida, M; Matsumoto, K; Moriyama, H; Saito, H; Yoshikawa, M | 1 |
| Burroughs, M; Cabellos, C; Forrest, M; MacIntyre, DE; Prasad, S; Tuomanen, E | 1 |
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| Abela, AP; Daniel, EE; Janssen, LJ; O'Byrne, PM | 1 |
| Flohé, S; Heinrich, PC; Hörstmann-Jungemann, K; Kirkpatrick, CJ; Klosterhalfen, B; Offner, F; Vogel, P | 1 |
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| Horii, T; Kobayashi, Y; Okuyama, H; Saito, K; Satouchi, K; Watanabe, S; Yoshida, Y | 1 |
| Kushner, I | 1 |
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| Hirasawa, N; Mue, S; Ohuchi, K; Omata, M; Tsurufuji, S; Watanabe, M | 1 |
| Sharma, JN | 1 |
| Buckman, D; Iverson, L; Srivastava, A; Thomas, TK; Weis, W; Will, PC; Wilson, C | 1 |
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| Egido, J; Gomez-Chiarri, M; Gonzalez, E; Lerma, JL; Ortiz, A | 1 |
| Hayashi, M; Imai, Y; Oh-ishi, S | 1 |
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| Brain, SD; Buckley, TL; Rampart, M; Williams, TJ | 1 |
| Buehn, MJ; Dabney, JM; Dobbins, DE | 1 |
| Braquet, M; Egido, J; Gómez-Guerrero, C; González, E; Herrero-Beaumont, G; Maestre, C; Zarco, P | 1 |
| Mohsin, SS; Sharma, JN | 1 |
| McIntyre, TM; Otsuka, K; Prescott, SM; Zimmerman, GA | 1 |
| Daniel, EE; O'Byrne, P | 1 |
| Boney, RS; Rosenbaum, JT; Samples, JR; Valone, FH | 1 |
| Oda, M; Saito, K; Satouchi, K | 1 |
| Kantengwa, S; Polla, BS | 1 |
| Dusting, GJ; Stewart, AG | 1 |
| Hirasawa, N; Mue, S; Ohuchi, K; Omata, M; Sugidachi, A; Tsurufuji, S; Watanabe, M | 1 |
| Chilton, FH; Lichtenstein, LM | 1 |
| Maraganore, JM; McIntyre, TM; Prescott, SM; Seeger, AR; Zimmerman, GA | 1 |
| Srimal, RC; Srivastava, R | 1 |
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| Bussolino, F; Camussi, G; Esposito, C; Metafora, S; Peluso, G; Porta, R; Tetta, C | 1 |
| Conklyn, M; Conyers, G; Cramer, E; Milks, L; Showell, H | 1 |
| Csato, M; Dobozy, A; Judák, R; Kenderessy, AS | 1 |
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| Benveniste, J; Chignard, M; Coëffier, E; Delautier, D; Denizot, Y; Le Couedic, JP | 1 |
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| Hedqvist, P; Lindbom, L; Ohlén, A; Raud, J; Thureson-Klein, A | 1 |
| Baber, NS; Bolognese, JA; Goldenberg, MM; James, I; Sciberras, DG | 1 |
| Gustafson, KS; Jacob, HS; Nelson, RD; Vercellotti, GM; Yin, HQ | 1 |
| Bekemeier, H; Sänze, JU | 1 |
| Benveniste, J; Denizot, Y | 1 |
| Braquet, P; Hosford, D; Mencia-Huerta, JM; Sturk, A; ten Cate, JW | 1 |
| Coyle, AJ; Page, CP; Spina, D | 1 |
| Hsueh, W; Needleman, P; Spaethe, SM | 1 |
| Beneker, C; Meisters, TM; Pover, P; Raaijmakers, JA; van Geffen, EC | 1 |
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| Agrawal, DK; Bewtra, AK; Hopp, RJ; Townley, RG | 1 |
| Hayashi, I; Hayashi, M; Oh-ishi, S; Utsunomiya, I; Yamaki, K | 1 |
| Lee, TH | 1 |
| Ikeda, I; Oda, M; Saito, K; Satouchi, K | 1 |
| Brain, SD; Hellewell, PG; Jose, PJ; Nourshargh, S; Rampart, M; Williams, TJ | 1 |
| Braquet, P; Jancar, S; Sirois, P | 1 |
| Errasfa, M; Fradin, A; Poincelot-Canton, B; Rothhut, B; Russo-Marie, F | 1 |
| Archer, CB; MacDonald, DM; Morley, J; Page, CP; Paul, W; Sanjar, S | 1 |
| Ghezzi, E | 1 |
| Hellewell, PG; Jose, PJ; Williams, TJ | 1 |
| Cordeiro, RN; Hatmi, M; Lima, MC; Malanchère, E; Martins, MA; Silva, PM; Vargaftig, BB | 1 |
| Flower, RJ | 1 |
| Auer, H; Egger, D; Fechter, M; Popper, H | 1 |
| Beneker, C; De Boer, E; Harmsen, HJ; Raaijmakers, JA; Van Rozen, RJ | 1 |
| Stimler-Gerard, NP | 1 |
| Bodmer, JL; Bray, MA; McKearn-Smith, C; Metz-Virca, G; Virca, GD | 1 |
| Fortes, ZB; Lagente, V | 1 |
| Cordeiro, RS; Martins, MA; Silva, PM | 1 |
| Coyle, AJ; Page, CP; Robertson, DN | 1 |
| Blank, ML; Johnson, D; Lee, TC; Malone, B; Robinson, M; Snyder, F; Woodard, DS | 1 |
| Botting, R; Vane, J | 1 |
| Smith, TF | 1 |
| Hayashi, Y; Hirasawa, N; Ohuchi, K; Sugidachi, A; Tsurufuji, S; Watanabe, M | 1 |
| Peers, SH | 1 |
| Miadonna, A; Tedeschi, A | 1 |
| Rosenbaum, JT; Rubin, RM | 1 |
| Page, CP; Robertson, DN | 2 |
| Banner, B; Chapchap, P; Esquivel, CO; Makowka, L; Mazzaferro, V; Miller, C; Pan, C; Podesta, L; Pressley, D; Todo, S | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Packham, MA | 1 |
| Morley, J | 1 |
| Hayashi, M; Oh, S; Yamaki, K | 1 |
| Angle, MJ; McManus, LM; Pinckard, RN | 1 |
| McIntyre, TM; Prescott, SM; Zimmerman, GA | 1 |
| Oxholm, P; Winther, K | 1 |
| Alvemini, D; Morley, J; Page, CP; Sanjar, S | 1 |
| McManus, LM | 1 |
| Castro, HC; Cordeiro, RS; Lima, MC; Martins, MA; Neto, F; Silva, PM; Vargaftig, BB | 1 |
| Henderson, B; Higgs, GA; Pettipher, ER | 1 |
| Braquet, P; Cournot, A; Duchier, J; Guinot, P | 1 |
| Castanheira, JR; Cordeiro, RS; Faria Neto, HC; Martins, MA; Silva, PM; Vargaftig, BB | 1 |
| Morley, J; Page, CP | 1 |
| Archer, CB; MacDonald, DM; Morley, J; Page, CP; Paul, W | 1 |
| Harlan, JM | 1 |
| Ip, M; Kwan, S; Lam, WK; So, SY | 1 |
| Moore, TL; Weiss, TD | 1 |
| Benveniste, J; Dulioust, A; Haye-Legrand, I; Ninio, E; Roubin, R | 1 |
| Issekutz, AC; Szpejda, M | 1 |
| De Nucci, G; Fitzgerald, MF; Flower, RJ; Parente, L | 1 |
| Aliaga, M; Barbara, M; Caillol, V; Tarayre, JP; Tisne-Versailles, J | 1 |
| Archer, CB; Guerreiro, D; Morley, J; Page, CP | 1 |
130 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Innate Inflammatory Response
| Article | Year |
|---|---|
The association between dietary patterns and the novel inflammatory markers platelet-activating factor and lipoprotein-associated phospholipase A2: a systematic review.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Atherosclerosis; Biomarkers; Humans; Inflammation; Platelet Activating Factor | 2022 |
Utility of the Specialized Pro-Resolving Mediators as Diagnostic and Prognostic Biomarkers in Disease.
Topics: Biomarkers; Chromatography, Liquid; Eicosanoids; Humans; Inflammation; Platelet Activating Factor; Prognosis | 2022 |
PAF-induced inflammatory and immuno-allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects.
Topics: Conjunctivitis, Allergic; Eye Diseases; Histamine; Humans; Inflammation; Platelet Activating Factor | 2022 |
Platelet Activating Factor (PAF): A Mediator of Inflammation.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Anaphylaxis; Animals; Child; Humans; Inflammation; Platelet Activating Factor | 2022 |
Inflammatory Pathways Following Subarachnoid Hemorrhage.
Topics: Brain Ischemia; Endothelin-1; Humans; Inflammation; Intracranial Aneurysm; Metabolic Networks and Pathways; Mitogen-Activated Protein Kinases; Oxyhemoglobins; Platelet Activating Factor; Reactive Oxygen Species; Serotonin; Subarachnoid Hemorrhage; Thrombin | 2020 |
Effect of acyl and alkyl analogs of platelet-activating factor on inflammatory signaling.
Topics: Acylation; Alkylation; Humans; Inflammation; Platelet Activating Factor; Signal Transduction | 2020 |
The roles of small-molecule inflammatory mediators in rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Inflammation; Inflammation Mediators; Interleukin-1alpha; Interleukin-6; Leukotrienes; Lipoxins; Nitric Oxide; Platelet Activating Factor; Prostaglandins; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2021 |
COVID-19, microthromboses, inflammation, and platelet activating factor.
Topics: Antiviral Agents; Blood Platelets; COVID-19; Cyproheptadine; Disseminated Intravascular Coagulation; Gene Expression Regulation; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Lung; Luteolin; Mast Cells; Platelet Activating Factor; Pulmonary Embolism; Quercetin; SARS-CoV-2; Severe Acute Respiratory Syndrome | 2020 |
Inflammation, not Cholesterol, Is a Cause of Chronic Disease.
Topics: Cholesterol; Chronic Disease; Diet, Healthy; Diet, Mediterranean; Exercise; Health Behavior; Humans; Incidence; Inflammation; Life Style; Observational Studies as Topic; Platelet Activating Factor; Risk Factors | 2018 |
Platelet activating factors in depression and coronary artery disease: a potential biomarker related to inflammatory mechanisms and neurodegeneration.
Topics: Animals; Biomarkers; Blood Platelets; Coronary Artery Disease; Depressive Disorder; Humans; Inflammation; Nerve Degeneration; Oxidative Stress; Platelet Activating Factor; Signal Transduction | 2013 |
Anaphylaxis and cardiovascular diseases: a dangerous liaison.
Topics: Anaphylaxis; Cardiovascular Diseases; Histamine; Humans; Inflammation; Mastocytosis; Platelet Activating Factor; Prostaglandins | 2014 |
Understanding the connection between platelet-activating factor, a UV-induced lipid mediator of inflammation, immune suppression and skin cancer.
Topics: Animals; Blood Platelets; DNA Repair; Humans; Immunosuppression Therapy; Inflammation; Mast Cells; Platelet Activating Factor; Receptors, G-Protein-Coupled; Skin; Skin Neoplasms; Ultraviolet Rays | 2016 |
Current Understanding of Platelet-Activating Factor Signaling in Central Nervous System Diseases.
Topics: Animals; Blood Platelets; Central Nervous System Diseases; Humans; Inflammation; Neurons; Platelet Activating Factor; Signal Transduction | 2017 |
Inflammation and melanoma metastasis.
Topics: Chemokines; Disease Progression; Humans; Immune System; Inflammation; Interleukins; Keratinocytes; Melanoma; Neoplasm Invasiveness; Neoplasm Metastasis; Platelet Activating Factor; Platelet Activation; Receptor, PAR-1; Stromal Cells | 2009 |
Mast cells: makers and breakers of allergic inflammation.
Topics: Animals; Antigen Presentation; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Cell Degranulation; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Inflammation; Interleukin-10; Lectins; Mast Cells; Mice; Platelet Activating Factor | 2009 |
Platelet activating factor/platelet activating factor receptor pathway as a potential therapeutic target in autoimmune diseases.
Topics: Animals; Autoimmune Diseases; Humans; Inflammation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction | 2009 |
Significance of lipid mediators in corneal injury and repair.
Topics: Animals; Arachidonic Acid; Cornea; Corneal Injuries; Humans; Inflammation; Lipid Metabolism; Platelet Activating Factor; Wound Healing | 2010 |
The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses.
Topics: Animals; Humans; Inflammation; Platelet Activating Factor; Sepsis; Signal Transduction | 2010 |
Role of lipoxins, resolvins, and other bioactive lipids in colon and pancreatic cancer.
Topics: Animals; Antineoplastic Agents; Arachidonic Acids; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Fatty Acids, Omega-3; Humans; Inflammation; Lipoxins; Lipoxygenases; Pancreatic Neoplasms; Platelet Activating Factor | 2011 |
Ocular actions of platelet-activating factor: clinical implications.
Topics: Animals; Eye Diseases; Humans; Inflammation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled | 2012 |
Emerging roles of secreted phospholipase A(2) enzymes: an update.
Topics: Animals; Arachidonic Acid; Atherosclerosis; Catalysis; Fatty Acids, Nonesterified; Glycerophospholipids; Humans; Hydrolysis; Inflammation; Mice; Phospholipases A2, Secretory; Platelet Activating Factor | 2013 |
Inflammation, bioactive lipids and atherosclerosis: potential roles of a lipoprotein-associated phospholipase A2, platelet activating factor-acetylhydrolase.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Arteriosclerosis; Humans; Inflammation; Lipids; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 2002 |
Endothelial protection by high-density lipoproteins: from bench to bedside.
Topics: Blood Coagulation; Cardiovascular Diseases; Endothelins; Endothelium, Vascular; Epoprostenol; Humans; Inflammation; Lipoproteins, HDL; Nitric Oxide; Platelet Activating Factor | 2003 |
Platelet-activating factor, a pleiotrophic mediator of physiological and pathological processes.
Topics: Acetyltransferases; Animals; Humans; Inflammation; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction | 2003 |
Acute pancreatitis: models, markers, and mediators.
Topics: Acute Disease; Adult; Animals; Biomarkers; Cytokines; Disease Models, Animal; Humans; Inflammation; Pancreatitis; Platelet Activating Factor | 2005 |
Plasma PAF-acetylhydrolase: an unfulfilled promise?
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Anti-Inflammatory Agents; Asthma; Atherosclerosis; Biomarkers; Disease Models, Animal; Humans; Inflammation; Lipoproteins, LDL; Macrophages; Oxidation-Reduction; Phosphatidylcholines; Platelet Activating Factor; Recombinant Proteins; Sepsis | 2006 |
[Biological action and clinical application of shark liver oil].
Topics: Animals; Antineoplastic Agents; Apoptosis; Diglycerides; Fish Oils; Humans; Inflammation; Neoplasms; Neovascularization, Pathologic; Platelet Activating Factor; Sharks; Signal Transduction; Squalene | 2006 |
The genetic basis of abdominal aortic aneurysms: a review.
Topics: Aortic Aneurysm, Abdominal; Family; Genetic Predisposition to Disease; HLA Antigens; Humans; Incidence; Inflammation; Inheritance Patterns; Interleukins; Matrix Metalloproteinases, Secreted; Methylenetetrahydrofolate Reductase (NADPH2); Models, Genetic; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Platelet Activating Factor; Polymorphism, Genetic; Receptors, CCR2; Receptors, Chemokine; Tissue Inhibitor of Metalloproteinases | 2007 |
The dialogue between endothelial cells and monocytes/macrophages in vascular syndromes.
Topics: Animals; Anti-Inflammatory Agents; Cardiovascular Agents; Cardiovascular Diseases; Cell Adhesion Molecules; Cell Communication; Chemokines; Endothelial Cells; Genomics; Humans; Inflammation; Intercellular Adhesion Molecule-1; Macrophages; Membrane Glycoproteins; Monocytes; P-Selectin; Platelet Activating Factor; Platelet Endothelial Cell Adhesion Molecule-1; Signal Transduction; Vascular Cell Adhesion Molecule-1 | 2007 |
Inflammation and melanoma growth and metastasis: the role of platelet-activating factor (PAF) and its receptor.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Humans; Inflammation; Lung Neoplasms; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Melanoma; Neovascularization, Pathologic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteins; Receptors, G-Protein-Coupled; Signal Transduction | 2007 |
Lipid mediators of inflammation and allergy.
Topics: Anaphylatoxins; Anaphylaxis; Animals; Antibodies; Arachidonic Acids; Autacoids; Blood Platelets; Bradykinin; Complement System Proteins; Dogs; Haplorhini; Histamine; Humans; Hypersensitivity; Inflammation; Lipids; Neutrophils; Platelet Activating Factor; Rabbits; Serotonin | 1982 |
The "new" chemical mediators of inflammation.
Topics: Animals; Arachidonic Acids; Autacoids; Humans; In Vitro Techniques; Inflammation; Oxygenases; Platelet Activating Factor; Prostaglandins | 1982 |
Mediators of anaphylaxis and inflammation.
Topics: Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Autacoids; Chemical Phenomena; Chemistry; Chemotactic Factors; Chemotactic Factors, Eosinophil; Histamine; Humans; Hydrolases; Inflammation; Leukocytes; Leukotriene B4; Mast Cells; Platelet Activating Factor; Prostaglandins; Serotonin; SRS-A; Structure-Activity Relationship; Thromboxanes; Vasoactive Intestinal Peptide | 1982 |
Inflammatory mediators and acute infections.
Topics: Arachidonic Acid; Arachidonic Acids; Complement Activation; Factor XII; Histamine; Humans; Infections; Inflammation; Neutrophils; Platelet Activating Factor; Receptors, Histamine H1; Receptors, Histamine H2; Shock, Septic | 1984 |
[Platelet activating factor (PAF)--a new chemical mediator of inflammation].
Topics: Animals; Capillary Permeability; Inflammation; Muscle Contraction; Neutrophils; Platelet Activating Factor; Rabbits | 1983 |
Platelets and the inflammatory response.
Topics: Animals; Blood Coagulation; Blood Platelets; Capillary Permeability; Cell Communication; Chemotactic Factors; Complement Activation; Humans; Inflammation; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet-Derived Growth Factor; Rabbits; Rats | 1983 |
Biology and biochemistry of platelet-activating factor.
Topics: Anaphylaxis; Animals; Blood Platelets; Calcium; Dogs; Guinea Pigs; Humans; Inflammation; Leukocytes; Lipid Metabolism; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats | 1983 |
Role of polymorphonuclear leukocytes in the vascular responses of acute inflammation.
Topics: Acute Disease; Animals; Blood Coagulation Factors; Capillary Permeability; Chemotactic Factors; Cricetinae; Dinoprostone; Epoprostenol; Inflammation; Neutrophils; Platelet Activating Factor; Prostaglandins E; Rabbits; Vasomotor System | 1984 |
Role of humoral mediators in adult respiratory distress syndrome.
Topics: Animals; Arachidonic Acids; Chemotaxis, Leukocyte; Chromones; Dogs; Guinea Pigs; Humans; Hypertension, Pulmonary; Inflammation; Ketanserin; Leukocyte Count; Leukocytes; Lung; Piperidines; Platelet Activating Factor; Pulmonary Embolism; Respiratory Distress Syndrome; Serotonin; Serotonin Antagonists; SRS-A; Thromboxane A2 | 1984 |
Mediators of inflammation.
Topics: Animals; Capillary Permeability; Chemotaxis, Leukocyte; Complement C5; Histamine; Humans; Hyperemia; Inflammation; Kinins; Peptides; Platelet Activating Factor; Prostaglandins; Vasodilation | 1983 |
[Blood platelets, prostaglandin and complement interactions in inflammation].
Topics: Animals; Blood Platelets; Complement Activation; Complement System Proteins; Humans; Inflammation; Platelet Activating Factor; Prostaglandins; Rabbits; Thromboxanes | 1982 |
Infection in massively injured patients.
Topics: Bacterial Infections; Blood Coagulation Factors; Burns; Complement Activation; Glucocorticoids; Glycoproteins; Humans; Immunity, Cellular; Inflammation; Macrophages; Plasminogen Activators; Platelet Activating Factor; Pyrogens; Sepsis; Wounds and Injuries | 1982 |
Molecular pathobiology of acetyl glyceryl ether phosphorylcholine: evidence for the structural and functional identity with platelet-activating factor.
Topics: Animals; Blood Platelets; Chemical Phenomena; Chemistry; Humans; Hypersensitivity; Inflammation; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Factor 4; Serotonin | 1980 |
[Animal models of bronchial hyperreactivity].
Topics: Adenosine; Animals; Asthma; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chronic Disease; Cytokines; Dextrans; Disease Models, Animal; Dogs; Guinea Pigs; Inflammation; Leukotrienes; Lipoxygenase; Mast Cells; Ozone; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Tachykinins | 1994 |
Platelet-activating factor and the cytokine network in inflammatory processes.
Topics: Animals; Asthma; Cytokines; Endothelium, Vascular; Humans; Inflammation; Lymphocytes; Platelet Activating Factor | 1994 |
Animal models of necrotizing enterocolitis.
Topics: Animals; Disease Models, Animal; Enterocolitis, Pseudomembranous; Ileum; Inflammation; Ischemia; Platelet Activating Factor; Reperfusion; Splanchnic Circulation | 1995 |
Inflammatory mediators and intestinal injury.
Topics: Animals; Endothelins; Enterocolitis, Pseudomembranous; Humans; Infant, Newborn; Inflammation; Intestines; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 1994 |
Platelet-activating factor antagonists: scientific background and possible clinical applications.
Topics: Animals; Antibodies, Monoclonal; Brain Ischemia; Bronchoconstriction; Humans; Inflammation; Lipopolysaccharides; Myocardial Ischemia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic | 1994 |
Antilipid mediator and antioxidant therapy in adult respiratory distress syndrome.
Topics: Acetylcysteine; Adrenal Cortex Hormones; Antioxidants; Clinical Trials as Topic; Disease Models, Animal; Epoprostenol; Humans; Inflammation; Intensive Care Units; Leukotrienes; Lipid Peroxidation; Middle Aged; Platelet Activating Factor; Respiratory Distress Syndrome; Thromboxanes; Treatment Failure | 1993 |
[Etiology of "pouchitis"].
Topics: Bacterial Infections; Bile Acids and Salts; Fatty Acids, Volatile; Free Radicals; Gastrointestinal Hormones; Humans; Ileitis; Inflammation; Platelet Activating Factor; Proctocolectomy, Restorative | 1993 |
[Microcirculation and rheology].
Topics: Capillary Permeability; Capillary Resistance; Cytokines; Humans; Inflammation; Microcirculation; Platelet Activating Factor; Rheology; Vasoconstriction; Venous Insufficiency | 1994 |
An overview of glucocorticoid anti-inflammatory actions.
Topics: Anti-Inflammatory Agents; Arachidonic Acid; Blood Vessels; Cytokines; Endothelium, Vascular; Epithelium; Glucocorticoids; Humans; Inflammation; Interleukins; Leukocyte Count; Leukocytes; Platelet Activating Factor; Steroids | 1993 |
Secondary organ dysfunction. From clinical perspectives to molecular mediators.
Topics: Antibodies, Monoclonal; Critical Care; Cytokines; Eicosanoids; Energy Metabolism; Humans; Inflammation; Multiple Organ Failure; Nitric Oxide; Platelet Activating Factor; Reactive Oxygen Species; Resuscitation; Risk Factors; Severity of Illness Index; Survival Rate | 1993 |
New perspectives on basic mechanisms in lung disease. 3. Drug intervention in asthma: present and future.
Topics: Asthma; Forecasting; Humans; Inflammation; Leukotrienes; Platelet Activating Factor; Technology, Pharmaceutical | 1993 |
Splanchnic ischaemia/reperfusion and multiple organ failure.
Topics: Animals; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Rats; Reperfusion Injury; Splanchnic Circulation | 1996 |
PAF response to inflammatory and non-inflammatory stimuli.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Anterior Chamber; Genitalia, Male; Inflammation; Ischemia; Male; Phospholipases A; Platelet Activating Factor; Rabbits; Saccharomyces cerevisiae | 1996 |
Cigarettes and the wages of sn-2: oxidized species of PAF in smoking hamsters.
Topics: Animals; Cricetinae; Cytokines; Free Radicals; Humans; Inflammation; Leukocytes; Platelet Activating Factor; Smoking | 1997 |
[Analysis of chemical mediators involved in acute inflammatory reaction with the rat pleurisy model].
Topics: Animals; Arachidonic Acid; Capillary Permeability; Carrageenan; Cell Movement; Chemokines; Complement System Proteins; Disease Models, Animal; Eicosanoids; Histamine; Inflammation; Kallikrein-Kinin System; Male; Neutrophils; Platelet Activating Factor; Pleurisy; Rats; Zymosan | 1997 |
Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies.
Topics: Adrenal Cortex Hormones; Anticoagulants; Antioxidants; Aprotinin; Arachidonic Acids; Cardiopulmonary Bypass; Cell Adhesion Molecules; Complement Activation; Cytokines; Endothelins; Endotoxins; Equipment Design; Free Radicals; Gene Expression; Heparin; Humans; Inflammation; Inflammation Mediators; Leukocytes; Leukopenia; Nitric Oxide; Platelet Activating Factor; Reactive Oxygen Species; Serine Proteinase Inhibitors; Systemic Inflammatory Response Syndrome; Ultrafiltration | 1997 |
Relevance of platelet-activating factor in inflammation and sepsis: mechanisms and kinetics of removal in extracorporeal treatments.
Topics: Adsorption; Animals; Cell Adhesion; Endothelium, Vascular; Hemofiltration; Humans; Inflammation; Platelet Activating Factor; Sepsis | 1997 |
The interplay between primary and secondary cytokines. Cytokines involved in the regulation of monocyte recruitment.
Topics: Chemokine CCL2; Chemokine CCL4; Chemokine CCL7; Colony-Stimulating Factors; Cytokines; Humans; Inflammation; Interleukin-1; Interleukin-6; Macrophage Inflammatory Proteins; Monocyte Chemoattractant Proteins; Platelet Activating Factor; Receptors, Interleukin-1; Tumor Necrosis Factor-alpha | 1997 |
Dietary fat, breast cancer, and nonspecific immunity.
Topics: Animals; Breast Neoplasms; Dietary Fats; Female; Humans; Immunity; Inflammation; Mammary Neoplasms, Experimental; Platelet Activating Factor; Tumor Cells, Cultured | 1998 |
Lipid mediators in inflammatory disorders.
Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Fatty Acids, Omega-3; Humans; Inflammation; Inflammation Mediators; Leukotriene Antagonists; Lipid Metabolism; Lipoxygenase Inhibitors; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Prostaglandins | 1998 |
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
Topics: Animals; Arteriosclerosis; Blood Cells; Blood Coagulation; Cell Adhesion; Cell Adhesion Molecules; Cell Differentiation; Cells, Cultured; Endothelial Growth Factors; Endothelins; Endothelium, Vascular; Epoprostenol; Extracellular Matrix; Female; Fibrinolysis; Fibroblast Growth Factor 2; Hemodynamics; Humans; Inflammation; Lymphokines; Male; Mice; Neovascularization, Physiologic; Nitric Oxide; Platelet Activating Factor; Pre-Eclampsia; Pregnancy; Thrombosis; Umbilical Veins; Vascular Diseases; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Pulmonary hypertension and inflammation.
Topics: Animals; Arachidonate 5-Lipoxygenase; Endothelial Growth Factors; Endothelins; Humans; Hypertension, Pulmonary; Inflammation; Insulin-Like Growth Factor I; Lymphokines; Platelet Activating Factor; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Mechanisms of cell signaling in immune-mediated inflammation.
Topics: Anaphylatoxins; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chemokines; Chemotactic Factors; Dinoprostone; GTP-Binding Proteins; Immunoglobulin G; Inflammation; Leukocytes; Leukotriene B4; Leukotrienes; Lipids; Mice; Models, Biological; NF-kappa B; Phagocytes; Phospholipases A; Platelet Activating Factor; Signal Transduction; Thromboxane A2 | 1998 |
Regulation of platelet-activating factor (PAF) activity in human diseases by phospholipase A2 inhibitors, PAF acetylhydrolases, PAF receptor antagonists and free radical scavengers.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Enzyme Inhibitors; Free Radical Scavengers; Humans; Inflammation; Ischemia; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1999 |
Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice.
Topics: Amino Acid Sequence; Animals; Guinea Pigs; Humans; Inflammation; Mice; Mice, Knockout; Mice, Transgenic; Molecular Sequence Data; Phenotype; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Binding; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sequence Alignment; Signal Transduction | 2000 |
[Evaluation of time course and inter-relationship of inflammatory mediators in experimental inflammatory reaction].
Topics: Animals; Complement System Proteins; Cytokines; Histamine; Humans; Inflammation; Inflammation Mediators; Kallikrein-Kinin System; Platelet Activating Factor; Rats; Time Factors | 2000 |
Bioactive phospholipid oxidation products.
Topics: Animals; Cricetinae; Free Radicals; Gas Chromatography-Mass Spectrometry; Glycerophospholipids; Humans; Inflammation; Lipid Peroxidation; Lipoproteins, LDL; Mass Spectrometry; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Smoke | 2000 |
Platelet-activating factor and related lipid mediators.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Humans; Inflammation; Leukocytes; Oxidation-Reduction; Phospholipases A; Phospholipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction | 2000 |
Platelet-activating factor acetylhydrolases in health and disease.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Anti-Inflammatory Agents; Biomarkers; Cardiovascular Diseases; Cell Line; Cells, Cultured; Cloning, Molecular; Erythrocytes; Europe; Gene Expression Regulation; Humans; Inflammation; Isoenzymes; Japan; Mutation; Phospholipases A; Phospholipids; Platelet Activating Factor; Substrate Specificity; Tumor Cells, Cultured | 2000 |
Lipid inflammatory mediators: leukotrienes, prostaglandins, platelet-activating factor.
Topics: Animals; Asthma; Eicosanoids; Humans; Hypersensitivity; Inflammation; Inflammation Mediators; Leukotrienes; Lipid Metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Platelet Activating Factor; Prostaglandins | 2002 |
Lipoprotein-associated phospholipase A2: a potential new risk factor for coronary artery disease and a therapeutic target.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Biomarkers; Coronary Artery Disease; Enzyme Inhibitors; Fatty Acids, Nonesterified; Humans; Infections; Inflammation; Lipoproteins, LDL; Lysophosphatidylcholines; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Risk Factors | 2001 |
Importance of microcirculatory disturbances in the pathogenesis of pancreatitis.
Topics: Acute Disease; Animals; Capillary Permeability; Chronic Disease; Endothelins; Free Radicals; Humans; Inflammation; Ischemia; Microcirculation; Nitric Oxide; Pancreas; Pancreatitis; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Rats | 2001 |
Asthma as a chronic inflammatory disease and the implications for future therapy.
Topics: Adrenergic beta-Agonists; Asthma; Blood Platelets; Bronchoconstriction; Bronchodilator Agents; Chronic Disease; Eosinophils; Humans; Inflammation; Lung; Platelet Activating Factor | 1992 |
Neutrophil chemotactic factors.
Topics: Animals; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Humans; Inflammation; Leukotriene B4; Neuropeptides; Neutrophils; Platelet Activating Factor; Platelet Factor 4 | 1991 |
Platelet activating factor and asthma.
Topics: Animals; Asthma; Humans; Inflammation; Models, Biological; Muscle, Smooth; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Physiological Phenomena; Respiratory System | 1991 |
Platelet-activating factor (PAF)--a putative mediator in inflammatory tissue injury.
Topics: Animals; Blood Platelets; Cytokines; Humans; Inflammation; Leukotrienes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reperfusion Injury; Signal Transduction | 1991 |
LTB4 and PAF in the cytokine network.
Topics: Animals; Cytokines; Humans; Inflammation; Interferon-gamma; Interleukin-1; Interleukin-6; Leukotriene B4; Macrophages; Models, Biological; Monocytes; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 1991 |
C-reactive protein and the acute-phase response.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Blood Sedimentation; C-Reactive Protein; Complement Activation; Humans; Inflammation; Neutrophils; Phagocytosis; Platelet Activating Factor | 1990 |
Pro-inflammatory actions of the platelet activating factor: relevance to rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Humans; Inflammation; Platelet Activating Factor; Rabbits; Rats | 1991 |
[The pathophysiological role of the platelet activating factor].
Topics: Animals; Asthma; Blood Pressure; Cardiac Output; Humans; Inflammation; Myocardial Contraction; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Shock | 1991 |
Paf-acether in human skin.
Topics: Humans; Inflammation; Platelet Activating Factor; Skin; Skin Physiological Phenomena | 1991 |
The role of platelet-activating factor (PAF) in experimental glomerular injury.
Topics: Animals; Glomerulonephritis; Inflammation; Kidney; Kidney Glomerulus; Nephrotic Syndrome; Platelet Activating Factor | 1991 |
Modification of the eicosanoid system and cell signalling by precursor fatty acids.
Topics: Animals; Arteriosclerosis; Calcium; Cell Division; Dietary Fats; Diglycerides; Eicosanoids; Fatty Acids, Essential; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Free Radicals; Humans; Inflammation; Interleukin-1; Membrane Lipids; Models, Biological; Nitric Oxide; Oxygen; Platelet Activating Factor; Signal Transduction; Tumor Necrosis Factor-alpha | 1991 |
Dietary omega-3 fatty acids: effects on lipid mediators of inflammation and rheumatoid arthritis.
Topics: Arachidonate 5-Lipoxygenase; Arthritis, Rheumatoid; Dietary Fats; Fatty Acids, Omega-3; Humans; Inflammation; Lipids; Platelet Activating Factor | 1991 |
Molecular genetics, structure, and function of C-reactive protein.
Topics: Animals; C-Reactive Protein; Complement Pathway, Classical; Genes; Humans; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Opsonin Proteins; Platelet Activating Factor; Protein Binding; Protein Conformation; Receptors, Fc | 1991 |
The role of chemical mediators in the pathogenesis of inflammation with emphasis on the kinin system.
Topics: Anaphylatoxins; Animals; Autacoids; Complement System Proteins; Humans; Inflammation; Interleukin-1; Kallikreins; Kinins; Neutrophils; Platelet Activating Factor | 1990 |
Brief review: molecular mechanisms of neutrophil binding to endothelium involving platelet-activating factor and cytokines.
Topics: Antigens, CD; CD18 Antigens; Cell Adhesion; Cytokines; Endothelium, Vascular; Humans; In Vitro Techniques; Inflammation; Macrophage-1 Antigen; Neutrophils; Platelet Activating Factor; Receptors, Leukocyte-Adhesion | 1990 |
Heat shock proteins and inflammation.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Arthritis; Asthma; Cytokines; Extracellular Matrix; Fever; Heat-Shock Proteins; Humans; Inflammation; Leukotrienes; Metallothionein; Phagocytosis; Platelet Activating Factor; Prostaglandins | 1991 |
Overview of eicosanoid metabolism and relationship to platelet-activating factor.
Topics: Animals; Eicosanoids; Humans; Inflammation; Platelet Activating Factor | 1990 |
Lipid mediators of the allergic reaction.
Topics: Animals; Arachidonic Acids; Basophils; Eicosanoids; Fatty Acids, Unsaturated; Hypersensitivity; Inflammation; Leukotrienes; Lipoxygenase; Mast Cells; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1990 |
Arachidonic acid cascade and platelet-activating factor in the network of eye inflammatory mediators: therapeutic implications in uveitis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Autoimmunity; Endophthalmitis; Humans; Hypersensitivity; Inflammation; Platelet Activating Factor; Uveitis | 1990 |
Multiple organ failure: inflammatory priming and activation sequences promote autologous tissue injury.
Topics: Animals; Endotoxins; Humans; Inflammation; Lung; Multiple Organ Failure; Neutrophils; Peroxidase; Platelet Activating Factor; Respiratory Distress Syndrome | 1990 |
Phospholipase A2 activation is the pivotal step in the effector pathway of inflammation.
Topics: Animals; Cytokines; Enzyme Activation; Enzyme Induction; Humans; Inflammation; Interleukin-1; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 1990 |
The role of platelet-activating factor in inflammation.
Topics: Animals; Humans; Inflammation; Platelet Activating Factor | 1990 |
Lipid mediators of inflammation in gastric ulcer.
Topics: Animals; Humans; Inflammation; Leukotrienes; Models, Biological; Platelet Activating Factor; Prostaglandins; Stomach Ulcer; Thromboxanes | 1990 |
Mechanisms of glucocorticoid action in pulmonary disease.
Topics: Animals; Annexins; Arachidonic Acid; Arachidonic Acids; Asthma; Calcium-Binding Proteins; Chemotactic Factors; Glucocorticoids; Glycoproteins; Histamine Release; Humans; Inflammation; Lung; Lung Diseases; Platelet Activating Factor; Protein Biosynthesis; Pulmonary Gas Exchange; Receptors, Glucocorticoid; Status Asthmaticus | 1985 |
Mediators of airway inflammation.
Topics: Arachidonic Acids; Free Radicals; Histamine Release; Humans; Immunity, Cellular; Inflammation; Mast Cells; Membrane Lipids; Models, Biological; Platelet Activating Factor; Prostaglandins; Respiratory Tract Infections | 1986 |
Melanocytes, melanogenesis, and inflammation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Epidermal Cells; Humans; Inflammation; Keratins; Melanins; Melanocytes; Monophenol Monooxygenase; Phorbol Esters; Photosensitivity Disorders; Platelet Activating Factor; Prostaglandins; Swine | 1986 |
The synthesis, catabolism, and pathophysiological role of platelet-activating factor.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Infections; Humans; Immune System Diseases; Immunity, Cellular; Inflammation; Platelet Activating Factor; Platelet Activation | 1989 |
The role of platelet activating factor in allergic inflammation.
Topics: Animals; Humans; Hypersensitivity; Inflammation; Platelet Activating Factor | 1989 |
[The barley cell or mastocyte: cellular and molecular biology].
Topics: Anaphylaxis; Animals; Blood Coagulation Factors; Cell Differentiation; Cytoplasmic Granules; Exocytosis; Histamine Release; Humans; Hypersensitivity; Immunity, Cellular; Inflammation; Mast Cells; Mice; Platelet Activating Factor; Rats; Receptors, IgE; Receptors, Immunologic; Serotonin; SRS-A; Stem Cells | 1985 |
Platelet-activating factor and airway reactivity.
Topics: Animals; Asthma; Blood Platelets; Bronchial Spasm; Humans; Inflammation; Platelet Activating Factor; Respiratory Hypersensitivity | 1989 |
Asthma and allergic rhinitis.
Topics: Asthma; Humans; Inflammation; Mast Cells; Microcirculation; Nervous System; Platelet Activating Factor; Rhinitis | 1989 |
PAF--a perspective.
Topics: Animals; Humans; Inflammation; Platelet Activating Factor | 1989 |
Alteration in microvascular permeability induced by products released during inflammation.
Topics: Animals; Bradykinin; Capillary Permeability; Complement C5; Complement C5a; Histamine; Humans; Inflammation; Leukotriene B4; Lung; Neuropeptides; Platelet Activating Factor; Prostaglandins; SRS-A | 1988 |
Interactions of arachidonic acid metabolites and platelet activating factor and mechanism of action in hypersensitivity reactions.
Topics: Animals; Arachidonic Acids; Dinoprostone; Diterpenes; Eicosanoic Acids; Enzyme Activation; Ginkgolides; Guinea Pigs; Hypersensitivity; Inflammation; Lactones; Leukotriene B4; Lung; Muscle Contraction; Phospholipases; Phospholipases A; Platelet Activating Factor; Prostaglandins E; SRS-A; Thromboxane B2 | 1987 |
Autacoids and some mediators in allergic and non allergic forms.
Topics: Animals; Arachidonic Acids; Autacoids; Histamine; Humans; Hypersensitivity; Inflammation; Lipoxygenase; Models, Biological; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1986 |
Immunopharmacology of anaphylatoxin-induced bronchoconstrictor responses.
Topics: Anaphylatoxins; Animals; Bronchi; Bronchial Spasm; Complement Activation; Complement C3; Complement C3a; Complement C5; Complement C5a; Dose-Response Relationship, Drug; Inflammation; Leukotriene B4; Lung; Mice; Muscle Contraction; Peptides; Platelet Activating Factor; SRS-A | 1986 |
Inflammatory mechanisms and nocturnal asthma.
Topics: Adenosine; Asthma; Blood Platelets; Circadian Rhythm; Eosinophils; Epithelium; Histamine; Humans; Inflammation; Lymphocytes; Macrophages; Mast Cells; Neutrophils; Platelet Activating Factor; Prostaglandins; SRS-A | 1988 |
Role of PAF-acether in the vascular events of inflammation.
Topics: Capillary Permeability; Humans; Inflammation; Platelet Activating Factor; Vasodilation | 1988 |
Proinflammatory activity of platelet-activating factor: pharmacological modulation and cellular involvement.
Topics: Blood Platelets; Edema; Humans; Inflammation; Leukocytes; Platelet Activating Factor | 1988 |
Drugs affecting pulmonary responses to platelet activating factor as novel anti-asthma drugs.
Topics: Animals; Asthma; Blood Platelets; Humans; Inflammation; Lung; Platelet Activating Factor | 1988 |
Inflammation and the mechanism of action of anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Bradykinin; Colchicine; Cyclooxygenase Inhibitors; Gold; Histamine; Humans; Inflammation; Interleukin-1; Lipoxygenase Inhibitors; Platelet Activating Factor; Salicylates | 1987 |
Allergy and pseudoallergy: an overview of basic mechanisms.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Basophils; Chemotaxis; Drug Hypersensitivity; Histamine; Humans; Hypersensitivity; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Inflammation; Mast Cells; Platelet Activating Factor | 1987 |
[Mediators of immunologic inflammation of the respiratory tract].
Topics: Allergens; Arachidonic Acid; Arachidonic Acids; Asthma; Blood Platelets; Bronchial Provocation Tests; Histamine; Humans; Inflammation; Kinins; Leukocytes; Leukotrienes; Macrophages; Mast Cells; Nasal Provocation Tests; Platelet Activating Factor; Prostaglandins; Respiratory Hypersensitivity; Rhinitis, Allergic, Seasonal | 1988 |
Platelet-activating factor and asthma.
Topics: Asthma; Bronchi; Capillary Permeability; Humans; Inflammation; Muscle, Smooth; Platelet Activating Factor | 1988 |
The role of PAF in altered airway responsiveness.
Topics: Animals; Asthma; Bronchial Spasm; Humans; Inflammation; Platelet Activating Factor | 1988 |
New concepts in the pathogenesis of bronchial hyperresponsiveness.
Topics: Asthma; Axons; Eosinophils; Epithelial Cells; Humans; Inflammation; Macrophages; Mast Cells; Muscle Contraction; Neuropeptides; Platelet Activating Factor; Reflex | 1987 |
Platelet activation--an overview.
Topics: Animals; Blood Platelets; Hemostasis; Humans; Inflammation; Platelet Activating Factor; Platelet Aggregation; Thrombosis | 1987 |
Properties of PAF relevant to asthma.
Topics: Animals; Asthma; Bronchi; Humans; Inflammation; Platelet Activating Factor | 1987 |
PAF and airway hyperreactivity; prospects for novel prophylactic anti-asthma drugs.
Topics: Animals; Asthma; Bronchi; Humans; Inflammation; Platelet Activating Factor | 1987 |
Thrombocyte involvement in immune inflammatory reactions.
Topics: Antigen-Antibody Reactions; Antigens, Surface; Blood Coagulation; Blood Platelets; Cell Membrane; Cell Survival; Collagen; Complement System Proteins; Contractile Proteins; Cytoplasmic Granules; Humans; Inflammation; Lymphokines; Neutrophils; Phagocytosis; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Receptors, Fc | 1986 |
Inflammatory mediators of asthma.
Topics: Airway Resistance; Allergens; Animals; Asthma; Blood Platelets; Bronchial Provocation Tests; Bronchial Spasm; Humans; Inflammation; Mast Cells; Platelet Activating Factor; Respiratory Hypersensitivity | 1986 |
Age dependency of the inflammatory response.
Topics: Aging; Amines; Animals; Chemotactic Factors; Humans; Inflammation; Platelet Activating Factor; Prostaglandins; Vasoconstriction | 1986 |
Pathobiology of platelet-activating factors.
Topics: Animals; Cardiovascular Diseases; Humans; Inflammation; Lung Diseases; Platelet Activating Factor | 1986 |
Leukocyte-endothelial interactions.
Topics: Antigen-Presenting Cells; Antigens; Capillary Permeability; Cell Adhesion; Cell Membrane; Cell Movement; Culture Techniques; Cytoplasmic Granules; Endothelium; Glycoproteins; Humans; Inflammation; Interleukin-1; Isoelectric Point; Lactoferrin; Leukocytes; Lipoxygenase; Lymphocytes; Monocytes; Neutrophils; Phospholipases; Platelet Activating Factor; Platelet Adhesiveness | 1985 |
Mediators of inflammation.
Topics: Arachidonic Acid; Arachidonic Acids; Chemotactic Factors, Eosinophil; Complement Membrane Attack Complex; Complement Pathway, Alternative; Complement Pathway, Classical; Complement System Proteins; Factor XI; Factor XII; Histamine; Humans; Inflammation; Kininogens; Mast Cells; Platelet Activating Factor; Prekallikrein | 1985 |
5 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Innate Inflammatory Response
| Article | Year |
|---|---|
Resolvin E2 formation and impact in inflammation resolution.
Topics: Animals; Chemotaxis; Down-Regulation; Eicosapentaenoic Acid; Female; Humans; Immunity, Innate; Inflammation; Integrins; Male; Mice; Neutrophils; Phagocytosis; Platelet Activating Factor | 2012 |
The impact of intravenous fat emulsion administration in acute lung injury.
Topics: Adolescent; Adult; Aged; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Case-Control Studies; Drug Monitoring; Fat Emulsions, Intravenous; Female; Humans; Inflammation; Lung Compliance; Male; Middle Aged; Neutrophils; Phospholipids; Platelet Activating Factor; Proteins; Pulmonary Circulation; Pulmonary Gas Exchange; Respiration, Artificial; Respiratory Distress Syndrome; Survival Analysis; Treatment Outcome; Vascular Resistance | 2004 |
Failure of salmeterol to inhibit circulating white cell responses and bronchoconstriction induced by platelet activating factor.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Bronchoconstriction; Double-Blind Method; Female; Humans; Inflammation; Leukocyte Count; Lymphocytes; Lymphopenia; Male; Neutrophils; Platelet Activating Factor; Salmeterol Xinafoate | 1992 |
Inflammatory responses to intradermal injection of platelet activating factor, histamine and prostaglandin E2 in healthy volunteers: a double blind investigation.
Topics: Dinoprostone; Double-Blind Method; Histamine Release; Humans; Inflammation; Injections, Intradermal; Male; Pain; Platelet Activating Factor; Prostaglandins E; Sensory Thresholds; Skin Tests | 1987 |
Inhibition of PAF-acether induced weal and flare reaction in man by a specific PAF antagonist.
Topics: Adult; Humans; Inflammation; Lactones; Male; Placebos; Plant Extracts; Platelet Activating Factor; Time Factors | 1986 |
275 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Innate Inflammatory Response
| Article | Year |
|---|---|
FNF-12, a novel benzylidene-chromanone derivative, attenuates inflammatory response in in vitro and in vivo asthma models mediated by M2-related Th2 cytokines via MAPK and NF-kB signaling.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Benzylidene Compounds; Cytokines; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Inflammation; Macrophages; MAP Kinase Signaling System; Models, Animal; NF-kappa B; Platelet Activating Factor; Rats; Th2 Cells | 2022 |
Malabaricone C derived from nutmeg inhibits arachidonate 5-lipoxygenase activity and ameliorates psoriasis-like skin inflammation in mice.
Topics: Animals; Arachidonate 5-Lipoxygenase; Inflammation; Leukotrienes; Mice; Myristica; Platelet Activating Factor; Psoriasis | 2022 |
Endothelial mechanisms for inactivation of inflammation-induced hyperpermeability.
Topics: Animals; Capillary Permeability; Endothelial Cells; Endothelium; Endothelium, Vascular; Humans; Inflammation; Mice; Mice, Knockout; Platelet Activating Factor; Vascular Endothelial Growth Factor A | 2023 |
B-cell-activating factor (BAFF) and platelet-activating factor (PAF) in pregnancies complicated by maternal obesity and diabetes: a preliminary study.
Topics: Biomarkers; Diabetes, Gestational; Female; Humans; Inflammation; Longitudinal Studies; Obesity; Obesity, Maternal; Platelet Activating Factor; Pregnancy; Prospective Studies | 2023 |
Pharmacokinetics and Changes in Lipid Mediator Profiling after Consumption of Specialized Pro-Resolving Lipid-Mediator-Enriched Marine Oil in Healthy Subjects.
Topics: Chromatography, Liquid; Docosahexaenoic Acids; Fatty Acids, Omega-3; Healthy Volunteers; Humans; Inflammation; Inflammation Mediators; Pilot Projects; Platelet Activating Factor; Tandem Mass Spectrometry | 2023 |
Cholesterol versus Inflammation as Cause of Chronic Diseases.
Topics: Cholesterol; Chronic Disease; Exercise; Humans; Inflammation; Platelet Activating Factor | 2019 |
Mechanisms and Treatment of Light-Induced Retinal Degeneration-Associated Inflammation: Insights from Biochemical Profiling of the Aqueous Humor.
Topics: Animals; Antioxidants; Aqueous Humor; Arachidonic Acid; Disease Models, Animal; Docosahexaenoic Acids; Edema; Inflammation; Light; Lipid Peroxidation; Macular Degeneration; Male; Mitochondria; Oxidative Stress; Oxylipins; Plastoquinone; Platelet Activating Factor; Rabbits; Retina; Retinal Degeneration | 2020 |
ROBO4 deletion ameliorates PAF-mediated skin inflammation via regulating the mRNA translation efficiency of LPCAT1/LPCAT2 and the expression of PAF receptor.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Animals; Blotting, Western; Computational Biology; Enzyme-Linked Immunosorbent Assay; Inflammation; Mass Spectrometry; Mice; Mice, Inbred C57BL; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Biosynthesis; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Sequence Analysis, RNA | 2020 |
Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury.
Topics: Animals; Blood Platelets; Cell Degranulation; Disease Susceptibility; Inflammation; Mast Cells; Organ Specificity; Platelet Activating Factor; Platelet Activation; Rats | 2020 |
Coronavirus 2019, Microthromboses, and Platelet Activating Factor.
Topics: Betacoronavirus; Coronavirus Infections; COVID-19; Humans; Inflammation; Mast Cells; Pandemics; Platelet Activating Factor; Platelet Aggregation; Pneumonia, Viral; SARS-CoV-2; Thrombosis | 2020 |
Activation of Neutrophil Granulocytes by Platelet-Activating Factor Is Impaired During Experimental Sepsis.
Topics: Animals; Endotoxemia; Female; Humans; Hydrogen-Ion Concentration; Inflammation; Male; Membrane Potentials; NADPH Oxidase 2; Neutrophil Activation; Platelet Activating Factor; Sepsis; Swine | 2021 |
GM-CSF- and M-CSF-primed macrophages present similar resolving but distinct inflammatory lipid mediator signatures.
Topics: Arachidonate 5-Lipoxygenase; Cell Differentiation; Eicosanoids; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation; Lipid Metabolism; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Neutrophils; Platelet Activating Factor | 2017 |
Synthesis of Human Neutrophil Extracellular Traps Contributes to Angiopoietin-Mediated In Vitro Proinflammatory and Proangiogenic Activities.
Topics: Angiopoietin-1; Angiopoietin-2; CD18 Antigens; Cells, Cultured; Endothelial Cells; Extracellular Matrix; Extracellular Traps; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Neutrophils; Platelet Activating Factor; Receptor, TIE-2; Signal Transduction; Up-Regulation | 2018 |
Platelets mediate protective neuroinflammation and promote neuronal plasticity at the site of neuronal injury.
Topics: Animals; Blood Platelets; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Encephalitis; Female; Glycolipids; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroimmunomodulation; Neuronal Plasticity; Neurons; Platelet Activating Factor; Serotonin | 2018 |
Induction of mast-cell accumulation by promutoxin, an Arg-49 phospholipase A2.
Topics: Animals; Bothrops; Cell Adhesion Molecules; Cyproheptadine; Ginkgolides; Histamine; Histamine Release; Inflammation; Lactones; Male; Mast Cells; Mice; Mice, Inbred BALB C; Peritoneum; Phospholipases A2; Phospholipases A2, Secretory; Platelet Activating Factor; Reptilian Proteins; Snake Venoms; Terfenadine | 2013 |
Alkyl and phenolic glycosides from Saussurea stella.
Topics: Animals; Anti-Inflammatory Agents; Coumaric Acids; Disaccharides; Female; Flavonoids; Furans; Glucosides; Glucuronidase; Glycosides; Hydroxybenzoates; Inflammation; Isoflavones; Lignans; Male; Molecular Structure; Neutrophils; Phytotherapy; Plant Extracts; Platelet Activating Factor; Quinic Acid; Rats, Wistar; Saussurea | 2013 |
Roles of BN52021 in platelet-activating factor pathway in inflammatory MS1 cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Fibrinolytic Agents; G-Protein-Coupled Receptor Kinases; Ginkgolides; Inflammation; Islets of Langerhans; Lactones; Lipopolysaccharides; Mice; p38 Mitogen-Activated Protein Kinases; Phospholipase C beta; Phospholipases A2; Platelet Activating Factor; Protein-Tyrosine Kinases; Signal Transduction | 2013 |
Down-regulation of LPCAT expression increases platelet-activating factor level in cirrhotic rat liver: potential antiinflammatory effect of silybin.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Animals; Antioxidants; Blotting, Western; Chromatography, Thin Layer; Down-Regulation; Gene Expression Regulation; Inflammation; Liver Cirrhosis; Male; Microsomes, Liver; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Silybin; Silymarin | 2013 |
Platelet-activating factor induces proliferation in differentiated keratinocytes.
Topics: Apoptosis; Cell Cycle; Cell Differentiation; Cell Line; Cell Movement; Cell Proliferation; Cyclooxygenase 2; Gene Expression Profiling; Gene Expression Regulation; Humans; Inflammation; Keratinocytes; Mitosis; Platelet Activating Factor; Re-Epithelialization; Wound Healing | 2013 |
Inositol-C2-PAF down-regulates components of the antigen presentation machinery in a 2D-model of epidermal inflammation.
Topics: Adaptive Immunity; Anti-Inflammatory Agents; Antigens, CD; Cell Culture Techniques; Cytokines; Gene Expression Regulation; Humans; Immunity, Innate; Inflammation; Inositol; Keratinocytes; Platelet Activating Factor; Protein Array Analysis | 2014 |
Cooperative role of endogenous leucotrienes and platelet-activating factor in ischaemia-reperfusion-mediated tissue injury.
Topics: Amidines; Animals; Azepines; Biological Assay; Carbamates; Dermis; Disease Models, Animal; Extravasation of Diagnostic and Therapeutic Materials; Extremities; Inflammation; Leukotriene B4; Leukotrienes; Male; Mice; Mice, Inbred C57BL; Myocardial Ischemia; Neutrophil Infiltration; Platelet Activating Factor; Platelet Membrane Glycoproteins; Propionates; Quinolines; Rabbits; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Reperfusion Injury; Triazoles | 2013 |
Rapid production of platelet-activating factor is induced by protein kinase Cα-mediated phosphorylation of lysophosphatidylcholine acyltransferase 2 protein.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Animals; CHO Cells; Cricetulus; Gene Knockdown Techniques; Inflammation; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Phosphorylation; Platelet Activating Factor; Protein Kinase C-alpha; Serine; Signal Transduction | 2014 |
Hematopoietic α7 nicotinic acetylcholine receptor deficiency increases inflammation and platelet activation status, but does not aggravate atherosclerosis.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Aorta; Aortic Diseases; Atherosclerosis; Blood Platelets; Bone Marrow Transplantation; Diet, Western; Disease Models, Animal; Female; Genotype; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Inflammation; Inflammation Mediators; Leukocytes; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Plaque, Atherosclerotic; Platelet Activating Factor; Receptors, LDL; Time Factors | 2015 |
Maresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective.
Topics: Animals; Arachidonate 12-Lipoxygenase; Blood Platelets; Bronchoalveolar Lavage Fluid; Cell Hypoxia; Chemotaxis, Leukocyte; Disease Models, Animal; Docosahexaenoic Acids; Heterografts; Humans; Hydrochloric Acid; Inflammation; Lung; Male; Metabolomics; Mice; Mice, Inbred BALB C; Molecular Structure; Neutrophils; Platelet Activating Factor; Platelet Transfusion; Recombinant Proteins; Respiratory Distress Syndrome; Thrombin | 2014 |
A platelet-activating factor (PAF) receptor deficiency exacerbates diet-induced obesity but PAF/PAF receptor signaling does not contribute to the development of obesity-induced chronic inflammation.
Topics: Animals; Cells, Cultured; Diet, High-Fat; Inflammation; Male; Mice; Mice, Knockout; Obesity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction | 2015 |
Attenuated Reactive Gliosis and Enhanced Functional Recovery Following Spinal Cord Injury in Null Mutant Mice of Platelet-Activating Factor Receptor.
Topics: Animals; Astrocytes; Axons; Cervical Vertebrae; Extracellular Matrix; Female; Forelimb; Gliosis; Inflammation; Mice, Inbred C57BL; Mice, Knockout; Microglia; Myelin Sheath; Neuronal Plasticity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Recovery of Function; Spinal Cord Injuries | 2016 |
Angiotensin peptides attenuate platelet-activating factor-induced inflammatory activity in rats.
Topics: Angiotensins; Animals; Edema; Inflammation; Male; Peptides; Platelet Activating Factor; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2015 |
Measuring Biomarkers for an Innovative Personal Food Profile.
Topics: B-Cell Activating Factor; Biomarkers; Diet; Food Analysis; Humans; Immunoglobulin G; Inflammation; Inflammation Mediators; Interleukin-6; Platelet Activating Factor; Precision Medicine; Sirtuins | 2015 |
Proteomic Analysis of Neutrophil Priming by PAF.
Topics: Cytokines; Humans; Inflammation; Mass Spectrometry; Neutrophils; Platelet Activating Factor; Proteomics; Reactive Oxygen Species; Systemic Inflammatory Response Syndrome | 2016 |
Erythrocyte deformability - A partner of the inflammatory response.
Topics: Abdominal Muscles; Animals; Blood Viscosity; Disease Models, Animal; Endothelial Cells; Erythrocyte Deformability; Erythrocytes; Inflammation; Intravital Microscopy; Leukocyte Rolling; Mice, Transgenic; Neutrophils; Nitric Oxide; Platelet Activating Factor; Regional Blood Flow; Stress, Mechanical; Time Factors; Venules | 2016 |
PAFR activation of NF-κB p65 or p105 precursor dictates pro- and anti-inflammatory responses during TLR activation in murine macrophages.
Topics: Animals; Cytokines; Inflammation; Inflammation Mediators; Interleukin-10; Lipopolysaccharides; Lipoproteins; Macrophages, Peritoneal; Male; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; NF-kappa B p50 Subunit; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptors; Transcription Factor RelA | 2016 |
Involvement of platelet-activating factor in ultraviolet B-induced hyperalgesia.
Topics: Animals; Bone Marrow Transplantation; Hyperalgesia; Inflammation; Lipids; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Neurons; Oxygen; Phospholipids; Platelet Activating Factor; Ultraviolet Rays | 2009 |
Peroxisome proliferator-activated receptor-alpha reduces inflammation and vascular leakage in a murine model of acute lung injury.
Topics: Acute Lung Injury; Animals; Capillaries; Disease Models, Animal; Endotoxins; Inflammation; Lipopolysaccharides; Mice; Mice, Transgenic; Peroxisome Proliferators; Platelet Activating Factor; PPAR alpha; Pressure; Pulmonary Artery; Pyrimidines | 2008 |
Internalization of eNOS via caveolae regulates PAF-induced inflammatory hyperpermeability to macromolecules.
Topics: Animals; Capillary Permeability; Cattle; Caveolae; Cells, Cultured; Dextrans; Dynamin II; Endocytosis; Endothelial Cells; Fluorescein-5-isothiocyanate; Inflammation; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Platelet Activating Factor; RNA Interference; RNA, Small Interfering; Time Factors; Transfection | 2008 |
The emerging roles of PAF acetylhydrolase.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Apoptosis; Humans; Inflammation; Platelet Activating Factor; Substrate Specificity | 2009 |
Protection of PMS777, a new AChE inhibitor with PAF antagonism, against amyloid-beta-induced neuronal apoptosis and neuroinflammation.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Furans; Humans; Inflammation; Neurons; Platelet Activating Factor; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2009 |
Common pathways for activation of proinflammatory gene expression by G protein-coupled receptors in primary lung epithelial and endothelial cells.
Topics: Animals; Chemokine CXCL1; Endothelial Cells; Epithelial Cells; Gene Expression Regulation; Humans; Inflammation; Interleukin-8; Lung; Male; Microvessels; Platelet Activating Factor; Rats; Receptors, G-Protein-Coupled; Signal Transduction; Substance P | 2009 |
Lipoxin a(4) attenuates microvascular fluid leak during inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Fluids; Capillary Permeability; Endothelium, Vascular; Female; Inflammation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lipoxins; Microcirculation; Models, Animal; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Signal Transduction | 2009 |
Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice.
Topics: Animals; Capillary Permeability; Erythrocyte Transfusion; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Inflammation; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Platelet Activating Factor; Receptors, Lysosphingolipid; Sphingosine | 2009 |
Platelet activating factor stimulates arachidonic acid release in differentiated keratinocytes via arachidonyl non-selective phospholipase A2.
Topics: Arachidonic Acid; Calcium; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Group IV Phospholipases A2; Group VI Phospholipases A2; Humans; Inflammation; Inflammation Mediators; Ionophores; Isoenzymes; Keratinocytes; Organometallic Compounds; Phospholipase A2 Inhibitors; Phospholipases A2; Phospholipases A2, Secretory; Platelet Activating Factor; Signal Transduction; Sulfides | 2010 |
Novel targets and regulatory ordeal by QT interval.
Topics: Animals; Electrocardiography; Heart Rate; Humans; Inflammation; Platelet Activating Factor; Rats; Thrombosis | 2010 |
Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Chronic Disease; Cysteine; Disease Models, Animal; Female; Humans; Indoles; Inflammation; Leukotriene B4; Leukotrienes; Lung; Male; Membrane Proteins; Mice; Pentanoic Acids; Platelet Activating Factor; Propionates; Rats; Substrate Specificity; Zymosan | 2010 |
Sphingosine-1-phosphate modulation of basal permeability and acute inflammatory responses in rat venular microvessels.
Topics: Acute Disease; Animals; Antigens, CD; Bradykinin; Cadherins; Capillary Permeability; Cell Adhesion; Cells, Cultured; Cortactin; Endothelial Cells; Fluorescent Antibody Technique; Humans; Inflammation; Lysophospholipids; Male; Membrane Proteins; Mesentery; Microscopy, Confocal; Occludin; Platelet Activating Factor; rac GTP-Binding Proteins; Rats; Sphingosine; Time Factors; Venules | 2010 |
Effects of the new benzimidazole derivative TAS-203, an orally active phosphodiesterase 4 inhibitor, on airway inflammation in rats and emetic responses in ferrets.
Topics: Animals; Anti-Inflammatory Agents; Benzimidazoles; Chemotaxis, Leukocyte; Cloning, Molecular; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Ferrets; Guinea Pigs; Humans; Inflammation; Lipopolysaccharides; Male; Nitriles; Phosphodiesterase 4 Inhibitors; Platelet Activating Factor; Rats; Rats, Inbred BN; Rats, Inbred Lew; Respiratory Tract Diseases; Tissue Distribution; Triazoles; Tumor Necrosis Factor-alpha; Vomiting | 2010 |
[Effects of p38 mitogen-activated protein kinase in protection of carbon monoxide against lipopolysaccharide induced rat small intestine injury].
Topics: Animals; Carbon Monoxide; Down-Regulation; Inflammation; Intercellular Adhesion Molecule-1; Intestine, Small; Lipopolysaccharides; Male; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Rats; Rats, Sprague-Dawley | 2009 |
Multiple phospholipase A2 enzymes participate in the inflammatory process in osteoarthritic cartilage.
Topics: Aged; Aged, 80 and over; Arachidonic Acid; Cartilage, Articular; Cells, Cultured; Chondrocytes; Dinoprostone; Female; Humans; Inflammation; Interleukin-1beta; Isoenzymes; Male; Middle Aged; Oleic Acid; Osteoarthritis, Hip; Osteoarthritis, Knee; Phospholipases A2; Platelet Activating Factor; RNA, Messenger; Tumor Necrosis Factor-alpha | 2011 |
The immune-modulating cytokine and endogenous Alarmin interleukin-33 is upregulated in skin exposed to inflammatory UVB radiation.
Topics: Adult; Animals; Blotting, Western; Carcinoma, Squamous Cell; Female; Fibroblasts; Fluorescent Antibody Technique; Humans; Inflammation; Interleukin-33; Interleukins; Keratinocytes; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neutrophils; Platelet Activating Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Skin Neoplasms; Ultraviolet Rays | 2011 |
Functional significance of cytosolic endothelial nitric-oxide synthase (eNOS): regulation of hyperpermeability.
Topics: Calibration; Cell Membrane; Cytosol; DNA, Complementary; Humans; Inflammation; Microscopy, Fluorescence; Nitric Oxide; Nitric Oxide Synthase Type III; Permeability; Phosphorylation; Platelet Activating Factor; Protein Transport; Subcellular Fractions | 2011 |
Esophageal disease: updated information on inflammation.
Topics: Esophageal Diseases; Humans; Inflammation; Mast Cells; Platelet Activating Factor | 2011 |
Lung endothelial cell platelet-activating factor production and inflammatory cell adherence are increased in response to cigarette smoke component exposure.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Cell Adhesion; Cell Line; Endothelial Cells; Group VI Phospholipases A2; Humans; Inflammation; Lung; Mice; Mice, Knockout; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pulmonary Disease, Chronic Obstructive; Receptors, G-Protein-Coupled; Tobacco Smoke Pollution | 2012 |
Pulmonary inflammation due to exercise-induced pulmonary haemorrhage in Thoroughbred colts during race training.
Topics: Animals; Bronchoalveolar Lavage Fluid; Hemorrhage; Horse Diseases; Horses; Inflammation; Lung Diseases; Macrophages, Alveolar; Male; Oxidative Stress; Physical Conditioning, Animal; Platelet Activating Factor | 2011 |
Loss of the platelet activating factor receptor in mice augments PMA-induced inflammation and cutaneous chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Synthetic biotinylated peptide compounds derived from Asp-hemolysin: novel potent inhibitors of platelet-activating factor.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Biotin; Biotinylation; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Fungal Proteins; Hemolysin Proteins; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Male; Peptide Fragments; Peptides; Platelet Activating Factor; Rats; Rats, Wistar | 2012 |
Vascular remodeling alters adhesion protein and cytoskeleton reactions to inflammatory stimuli resulting in enhanced permeability increases in rat venules.
Topics: Actins; Animals; Antigens, CD; Cadherins; Calcium; Capillary Permeability; Cell Adhesion; Cell Proliferation; Endothelium, Vascular; Female; Fura-2; Inflammation; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Stress Fibers; Venules | 2012 |
The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Immune System Diseases; Inflammation; Joint Diseases; Leukocyte Disorders; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, G-Protein-Coupled; Time Factors; Zymosan | 2013 |
Pathobiology of actinic keratosis: ultraviolet-dependent keratinocyte proliferation.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; DNA; fas Receptor; Humans; Immune Tolerance; Inflammation; Keratinocytes; Keratosis, Actinic; Platelet Activating Factor; Signal Transduction; Skin; Skin Neoplasms; Sunlight; T-Lymphocytes, Regulatory; Tumor Suppressor Protein p53; Ultraviolet Rays; Urocanic Acid | 2013 |
Ability to induce atrial fibrillation in the peri-operative period is associated with phosphorylation-dependent inhibition of TWIK protein-related acid-sensitive potassium channel 1 (TASK-1).
Topics: Animals; Atrial Fibrillation; CHO Cells; Cricetinae; Cricetulus; Dogs; Electrophysiology; Humans; Inflammation; Male; Muscle Cells; Nerve Tissue Proteins; Perioperative Period; Peroxidase; Phosphorylation; Platelet Activating Factor; Potassium Channels, Tandem Pore Domain; Protein Kinase C; Threonine | 2013 |
Endothelin-3 at low concentrations attenuates inflammatory responses via the endothelin B2 receptor.
Topics: Animals; Edema; Endothelin-3; Inflammation; Male; Nitric Oxide; Platelet Activating Factor; Rats; Rats, Wistar; Receptor, Endothelin B; Zymosan | 2013 |
Platelets, endothelial cells, inflammatory chemokines, and restenosis: complex signaling in the vascular play book.
Topics: Animals; Blood Platelets; Cell Adhesion; Cell Communication; Chemokine CCL5; Chemokines; Endothelium, Vascular; Graft Occlusion, Vascular; Humans; Inflammation; Leukocytes; Mice; P-Selectin; Platelet Activating Factor; Signal Transduction | 2002 |
Platelet-activating factor antagonists decrease the inflammatory nociceptive response in rats.
Topics: Animals; Azepines; Diterpenes; Dose-Response Relationship, Drug; Formaldehyde; Ginkgolides; Inflammation; Lactones; Male; Pain; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thienopyridines; Time Factors; Triazoles | 2002 |
Bradykinin-induced proinflammatory signaling mechanisms.
Topics: Animals; Antibodies, Monoclonal; Bradykinin; Capillary Permeability; Cell Adhesion; Cell Count; Enzyme Inhibitors; Enzymes; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Lymphatic System; Male; Mast Cells; Microcirculation; Microscopy, Video; P-Selectin; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Splanchnic Circulation; Video Recording | 2002 |
Influence of acyl and plasmalogenic analogs of platelet activating factor on chemotaxis of human leukocytes in vitro and their inflammatory and antiinflammatory activity in vivo.
Topics: Acylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cattle; Chemotaxis, Leukocyte; Disease Models, Animal; Edema; Hindlimb; Humans; Inflammation; Leukocytes; Plasmalogens; Platelet Activating Factor; Rats; Rats, Wistar; Time Factors | 2002 |
The long pentraxin PTX3 is synthesized in IgA glomerulonephritis and activates mesangial cells.
Topics: Animals; C-Reactive Protein; Cell Division; Cell Size; Cells, Cultured; CHO Cells; Cricetinae; Glomerular Mesangium; Glomerulonephritis, IGA; Hot Temperature; Humans; Inflammation; Platelet Activating Factor; Protein Binding; Recombinant Proteins; Serum Amyloid P-Component | 2003 |
A critical role of leukotriene B4 in neutrophil migration to infectious focus in cecal ligaton and puncture sepsis.
Topics: Animals; Cecum; Cell Movement; Dihydropyridines; Eicosanoids; Imidazoles; Indoles; Inflammation; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred C57BL; Neutrophils; Peritoneum; Platelet Activating Factor; Prostaglandins; Time Factors; Wounds, Penetrating | 2003 |
Resveratrol, a red wine constituent polyphenol, prevents superoxide-dependent inflammatory responses induced by ischemia/reperfusion, platelet-activating factor, or oxidants.
Topics: Animals; Antioxidants; Cell Adhesion; Flavonoids; Free Radicals; Hypoxanthine; Inflammation; Leukocytes; Leukotriene B4; Male; Oxidants; Phenols; Platelet Activating Factor; Polyphenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Superoxide Dismutase; Superoxides; Time Factors; Xanthine Oxidase | 2003 |
Endotoxins stimulate neutrophil adhesion followed by synthesis and release of platelet-activating factor in microparticles.
Topics: Blood Platelets; Calcium; Cell Adhesion; Cell Line; Endotoxins; Humans; Inflammation; Ligands; Lipid Metabolism; Mass Spectrometry; Microscopy, Confocal; Neutrophils; Oxygen; Platelet Activating Factor; Temperature; Time Factors | 2003 |
Copper stimulates the synthesis and release of interleukin-8 in human endothelial cells: a possible early role in systemic inflammatory responses.
Topics: Cells, Cultured; Copper; Culture Media; Cytokines; Dose-Response Relationship, Drug; Eicosanoids; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Interleukin-1; Interleukin-8; Oligopeptides; Peptides; Platelet Activating Factor; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha; Umbilical Veins | 2003 |
A new model for inflammation-induced preterm birth: the role of platelet-activating factor and Toll-like receptor-4.
Topics: Animals; Blotting, Western; Disease Models, Animal; Female; Immunohistochemistry; Inflammation; Lipopolysaccharides; Membrane Glycoproteins; Mice; Obstetric Labor, Premature; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Pregnancy; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Toll-Like Receptor 4; Toll-Like Receptors; Uterus | 2003 |
Ceramide lances the lungs.
Topics: Animals; Ceramides; Humans; Inflammation; Lung; Lysophospholipids; Mice; Platelet Activating Factor; Respiratory Distress Syndrome; Sphingomyelin Phosphodiesterase; Sphingosine; Tumor Necrosis Factor-alpha | 2004 |
Protective effect of pentoxifylline on volume-induced lung injury in newborn piglets.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Biomechanical Phenomena; Inflammation; Lung; Lung Diseases; Lung Injury; Pentoxifylline; Peroxidase; Placebos; Platelet Activating Factor; Respiration, Artificial; Swine; Thromboxane B2; Tidal Volume | 2004 |
Sponge-induced angiogenesis and inflammation in PAF receptor-deficient mice (PAFR-KO).
Topics: Acetylglucosaminidase; Administration, Topical; Animals; Blood Vessels; Chemokines; Dihydropyridines; Fibroblasts; Granulation Tissue; Granuloma; Hemoglobins; Imidazoles; Implants, Experimental; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Knockout; Neovascularization, Pathologic; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polyurethanes; Porifera; Receptors, G-Protein-Coupled; Skin | 2004 |
Lycopene in association with alpha-tocopherol or tomato lipophilic extracts enhances acyl-platelet-activating factor biosynthesis in endothelial cells during oxidative stress.
Topics: Acetyl-CoA C-Acetyltransferase; Acetyltransferases; alpha-Tocopherol; Animals; Antioxidants; Carotenoids; Cattle; Cells, Cultured; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrogen Peroxide; Inflammation; Lipoproteins, LDL; Lycopene; Oxidative Stress; Oxygen; Plant Extracts; Platelet Activating Factor; Pulmonary Artery; Solanum lycopersicum; Time Factors | 2004 |
Activation of extracellular signal-regulated kinase couples platelet-activating factor-induced adhesion and delayed apoptosis of human neutrophils.
Topics: Androstadienes; Apoptosis; bcl-Associated Death Protein; Carrier Proteins; Caspase 3; Caspases; CD11b Antigen; CD18 Antigens; Cell Adhesion; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flow Cytometry; Granulocytes; Humans; Inflammation; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Activating Factor; Signal Transduction; Time Factors; Up-Regulation; Wortmannin | 2004 |
Macrophage inflammatory protein-2 mediates the bowel injury induced by platelet-activating factor.
Topics: Animals; Antibodies, Blocking; Chemokine CXCL2; Chemokines; Chemokines, CXC; Gene Expression Regulation; Hematocrit; Hypotension; Ileum; Inflammation; Inflammation Mediators; Inflammatory Bowel Diseases; Intercellular Signaling Peptides and Proteins; Leukocyte Count; Leukopenia; Male; Monokines; Neutrophil Infiltration; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activ
Topics: Animals; Arachidonic Acid; Bronchoalveolar Lavage Fluid; CD11b Antigen; Cytosol; Dose-Response Relationship, Drug; Escherichia coli; Group IV Phospholipases A2; Humans; Inflammation; Ionomycin; Leukotriene B4; Mice; Mice, Transgenic; NADPH Oxidases; Neutrophils; Oxygen; Phagocytosis; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pneumonia; Pyrrolidines; Receptors, IgG; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Angiopoietins can directly activate endothelial cells and neutrophils to promote proinflammatory responses.
Topics: Angiopoietin-1; Angiopoietin-2; CD18 Antigens; Cell Adhesion; Cell Survival; Cells, Cultured; Drug Synergism; Endothelium, Vascular; Humans; Inflammation; Neutrophil Activation; Neutrophil Infiltration; Neutrophils; P-Selectin; Platelet Activating Factor; Protein Transport; Receptor, TIE-2; Umbilical Veins; Vascular Endothelial Growth Factor A | 2005 |
Calcium/calmodulin-dependent kinase II is required for platelet-activating factor priming.
Topics: Blood Platelets; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cytokines; Cytosol; Endotoxins; Escherichia coli; Humans; Immunoprecipitation; Inflammation; Interleukin-10; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; MAP Kinase Kinase 4; Membrane Glycoproteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Monocytes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Protein Isoforms; Receptors, Cell Surface; Signal Transduction; Time Factors; Toll-Like Receptor 4; Toll-Like Receptors; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2005 |
Activated leukocytes and endothelial cells enhance retention of ultrasound contrast microspheres containing perfluoropropane in inflamed venules.
Topics: Animals; Blood Pressure; Endothelial Cells; Erythrocytes; Fluorocarbons; Heart Rate; Inflammation; Kinetics; Leukocytes; Male; Microcirculation; Microscopy, Fluorescence; Microspheres; Platelet Activating Factor; Rats; Rats, Wistar; Ultrasonography; Venules | 2005 |
Platelet-activating factor and prostaglandin E2 impair esophageal ACh release in experimental esophagitis.
Topics: Acetylcholine; Animals; Cats; Dinoprostone; Esophagitis; Esophagus; Inflammation; Interleukin-1; Interleukin-6; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Reactive Oxygen Species | 2005 |
Regulating inflammation through the anti-inflammatory enzyme platelet-activating factor-acetylhydrolase.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Blood Platelets; Gene Expression Regulation; Inflammation; Phospholipases A2; Platelet Activating Factor; Polymorphism, Genetic | 2005 |
Platelet activating factor induces cytoskeletal reorganization through Rho family pathway in THP-1 macrophages.
Topics: Adenoviridae; Arteriosclerosis; beta-Galactosidase; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cytoskeleton; Gene Transfer Techniques; Guanine Nucleotide Dissociation Inhibitors; Guanosine Triphosphate; Humans; Immunoblotting; Inflammation; Macrophages; Platelet Activating Factor; Pseudopodia; rac1 GTP-Binding Protein; rho GTP-Binding Proteins; rho-Specific Guanine Nucleotide Dissociation Inhibitors; rhoA GTP-Binding Protein; Time Factors; Up-Regulation | 2005 |
[Inhibitory effect of ginkgolide B on angiogenesis in chronic inflammation].
Topics: Animals; Cell Line; Diterpenes; Female; Fibrinolytic Agents; Fibroblasts; Ginkgolides; Granuloma; Humans; Inflammation; Interleukin-1; Lactones; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Platelet Activating Factor; RNA, Messenger; Tumor Necrosis Factor-alpha; U937 Cells | 2005 |
Ultraviolet B radiation generates platelet-activating factor-like phospholipids underlying cutaneous damage.
Topics: Animals; Apoptosis; Calcium; Caspase 3; Caspases; Cell Line; Cell Transplantation; Chromatography, High Pressure Liquid; Epidermal Cells; Epidermis; Humans; Inflammation; Keratinocytes; Ligands; Light; Lipids; Mass Spectrometry; Mice; Mice, SCID; Models, Chemical; Neutrophils; Oxygen; Phospholipid Ethers; Phospholipids; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Skin; Time Factors; Tyrosine; Ultraviolet Rays; Xenopus | 2005 |
Effects of eccentric exercise-induced muscle injury on blood levels of platelet activating factor (PAF) and other inflammatory markers.
Topics: Adult; C-Reactive Protein; Complement C3; Creatine Kinase; Elbow Joint; Exercise; Fibrinogen; Humans; Inflammation; L-Lactate Dehydrogenase; Leukocyte Count; Male; Muscle Contraction; Muscle, Skeletal; Platelet Activating Factor; Torque | 2005 |
TNF-alpha induces the late-phase airway hyperresponsiveness and airway inflammation through cytosolic phospholipase A(2) activation.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytosol; Disease Models, Animal; Enzyme Activation; Histamine; Inflammation; Leukotriene B4; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Phospholipases A; Platelet Activating Factor; Pulmonary Eosinophilia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Staphylococcal lipoteichoic acid inhibits delayed-type hypersensitivity reactions via the platelet-activating factor receptor.
Topics: Animals; Calcium; Cell Line; Dermatitis, Atopic; Dinitrofluorobenzene; Drug Hypersensitivity; Drug Synergism; Humans; Hypersensitivity, Delayed; Inflammation; Interleukin-10; Lipopolysaccharides; Mice; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Skin; Staphylococcal Infections; Staphylococcus aureus; Teichoic Acids; Th1 Cells; Th2 Cells | 2005 |
Attenuation of folic acid-induced renal inflammatory injury in platelet-activating factor receptor-deficient mice.
Topics: Animals; Chemokine CCL2; Chemotaxis; Fibrosis; Folic Acid; Inflammation; Kidney Diseases; Leukocytes; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Time Factors; Tumor Necrosis Factor-alpha | 2006 |
Platelet-activating factor in cirrhotic liver and hepatocellular carcinoma.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Aged; Carcinoma, Hepatocellular; Cell Communication; Female; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Neovascularization, Pathologic; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 2006 |
Antiinflammatory and antiallodynic actions of the lignan niranthin isolated from Phyllanthus amarus. Evidence for interaction with platelet activating factor receptor.
Topics: Analgesics; Animals; Anisoles; Anti-Inflammatory Agents; Azepines; Binding, Competitive; Carrageenan; Cerebral Cortex; Dioxoles; Inflammation; Lignans; Male; Mice; Pain Measurement; Pain Threshold; Peroxidase; Phyllanthus; Plant Extracts; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pleurisy; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Tetrahydronaphthalenes; Time Factors; Triazoles | 2006 |
Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosis.
Topics: Animals; Apoptosis; Candida albicans; Candidiasis; Combined Modality Therapy; Female; Ficusin; Humans; Hypersensitivity, Delayed; Immune Tolerance; Immunosuppression Therapy; Inflammation; Interleukin-10; Lymphoma, T-Cell, Cutaneous; Male; Mice; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Psoriasis; PUVA Therapy; Receptors, G-Protein-Coupled; Signal Transduction | 2006 |
A role for inflammatory mediators in the induction of immunoregulatory B cells.
Topics: Adoptive Transfer; Animals; Antigens, CD19; B-Lymphocytes; Dermatitis, Contact; Dihydropyridines; Flow Cytometry; Fluorescein-5-isothiocyanate; Immune Tolerance; Inflammation; Interleukin-10; Leukocyte Common Antigens; Lymphocyte Activation; Mice; Mice, Mutant Strains; Platelet Activating Factor; Serotonin; Serotonin Antagonists; Ultraviolet Rays | 2006 |
A single enzyme catalyzes both platelet-activating factor production and membrane biogenesis of inflammatory cells. Cloning and characterization of acetyl-CoA:LYSO-PAF acetyltransferase.
Topics: Acetyltransferases; Animals; Cell Membrane; CHO Cells; Cloning, Molecular; Cricetinae; Cricetulus; Gene Expression Regulation, Enzymologic; Glycerophospholipids; Humans; Inflammation; Lipopolysaccharides; Macrophages, Peritoneal; Membrane Lipids; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Platelet Activating Factor | 2007 |
Dietary ganglioside inhibits acute inflammatory signals in intestinal mucosa and blood induced by systemic inflammation of Escherichia coli lipopolysaccharide.
Topics: Animals; Cholesterol; Dietary Fats; Dinoprostone; Gangliosides; Inflammation; Interleukin-1beta; Intestinal Mucosa; Leukotriene B4; Lipopolysaccharides; Male; Membrane Microdomains; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha | 2007 |
Tumor growth, angiogenesis and inflammation in mice lacking receptors for platelet activating factor (PAF).
Topics: Acetylglucosaminidase; Animals; Ascites; Carcinoma, Ehrlich Tumor; Chemokine CCL2; Chemokines, CXC; Inflammation; Mice; Mice, Inbred BALB C; Mice, Knockout; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Peritoneal Cavity; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Regional Blood Flow; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2007 |
Lipopolysaccharide-induced cerebral inflammatory damage and the therapeutic effect of platelet activating factor receptor antagonist.
Topics: Animals; Behavior, Animal; Brain Diseases; Fibrinolytic Agents; Ginkgolides; Hippocampus; Immunohistochemistry; Inflammation; Lactones; Lipopolysaccharides; Maze Learning; Microglia; Microscopy, Electron, Transmission; Neurons; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled | 2007 |
Identification of a novel noninflammatory biosynthetic pathway of platelet-activating factor.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Animals; Calcium; Inflammation; Lung; Macrophages; Mice; Mice, Inbred C57BL; Microsomes; Models, Biological; Platelet Activating Factor; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Transfection | 2008 |
Inhibition of photocarcinogenesis by platelet-activating factor or serotonin receptor antagonists.
Topics: Animals; Apoptosis; Epidermis; Female; Immune System; Inflammation; Light; Mice; Neoplasms, Radiation-Induced; Platelet Activating Factor; Receptors, Serotonin; Serotonin Antagonists; Skin Neoplasms; Sunlight; Ultraviolet Rays | 2008 |
Desensitization of acute inflammatory lesions to chemotaxins and endotoxin.
Topics: Acute Disease; Animals; Caseins; Chemotactic Factors; Desensitization, Immunologic; Dose-Response Relationship, Immunologic; Endotoxins; Female; Inflammation; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Zymosan | 1984 |
Release of platelet-activating factor (PAF-acether) and leukotrienes C and D from inflammatory macrophages.
Topics: Animals; Autacoids; Chromatography, High Pressure Liquid; Female; Inflammation; Lysophosphatidylcholines; Macrophages; Mice; Mice, Inbred C57BL; Platelet Activating Factor; SRS-A | 1982 |
Interdependence of inflammatory signals in various immunological systems.
Topics: Animals; Complement C5; Complement C5a; Eosinophils; Guinea Pigs; Histamine Release; Humans; Immunity, Cellular; Inflammation; Leukotriene B4; Muscle Contraction; Neutrophils; Platelet Activating Factor; Rats | 1983 |
[Mediators of inflammation. Their nature and their role].
Topics: Anti-Inflammatory Agents; Bradykinin; Histamine; Humans; Inflammation; Leukotriene B4; Platelet Activating Factor; Prostaglandins; Serotonin | 1982 |
Lipid and peptide mediators of inflammation. Summary.
Topics: Animals; Humans; Inflammation; Leukotriene B4; Peptide Hydrolases; Platelet Activating Factor; SRS-A | 1983 |
Inflammatory mediators released by complement-derived peptides.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Complement C3; Complement C3b; Complement C5; Complement C5a; Complement C5b; Complement System Proteins; Humans; Inflammation; Lysosomes; Oxygen; Peptides; Platelet Activating Factor | 1983 |
A new piece for the puzzle of inflammation.
Topics: Animals; Haplorhini; Humans; Inflammation; Platelet Activating Factor; Rabbits | 1984 |
Aggregation of bovine platelets by acetyl glyceryl ether phosphorylcholine (platelet activating factor).
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cattle; In Vitro Techniques; Inflammation; Platelet Activating Factor; Platelet Aggregation | 1984 |
On the nature of the vasoreactivity depressing factor (VDF) in inflammation and anaphylaxis in the rat and mouse.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alprostadil; Anaphylaxis; Animals; Anti-Inflammatory Agents; Epoprostenol; Female; Histamine; Indomethacin; Inflammation; Male; Mice; Mice, Inbred Strains; Norepinephrine; Platelet Activating Factor; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains; Serotonin; Vasopressins | 1984 |
Kinetics of neutrophil accumulation in acute inflammatory lesions induced by chemotaxins and chemotaxinigens.
Topics: Acute Disease; Animals; Caseins; Chemotactic Factors; Concanavalin A; Dose-Response Relationship, Immunologic; Endotoxins; Female; Inflammation; Kinetics; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Zymosan | 1984 |
PAF-acether: a putative mediator of asthma and inflammation.
Topics: Animals; Asthma; Guinea Pigs; Humans; Inflammation; Leukocytes; Lung; Platelet Activating Factor; Serum Albumin; Skin | 1983 |
Inflammatory actions of platelet activating factor (Pafacether) in guinea-pig skin.
Topics: Alprostadil; Animals; Blood Proteins; Erythrocyte Aggregation; Guinea Pigs; Inflammation; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Skin | 1983 |
Platelet-activating factor (PAF) as a mediator of neutrophil-platelet interactions in inflammation.
Topics: Arachidonic Acid; Arachidonic Acids; Basophils; Blood Coagulation Factors; Blood Platelets; Humans; Immunoglobulin E; In Vitro Techniques; Inflammation; Lysophosphatidylcholines; Neutrophils; Platelet Activating Factor | 1981 |
Release of platelet-activating factor (PAF-acether) and arachidonic acid metabolites from alveolar macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Humans; In Vitro Techniques; Inflammation; Lysophosphatidylcholines; Macrophages; Papio; Platelet Activating Factor; Pulmonary Alveoli; Rats | 1981 |
Effect of platelet activating factor on leukocytes. II. Enhancement of eosinophil chemotactic factor and beta-glucuronidase release.
Topics: Calcimycin; Chemotactic Factors; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Complement System Proteins; Drug Synergism; Eosinophils; Glucuronidase; Humans; Inflammation; Neutrophils; Platelet Activating Factor; Zymosan | 1982 |
Neutrophil and platelet interactions in "allergic" and inflammatory reactions: a role for acetyl glyceryl ether phosphorylcholine (platelet-activating factor).
Topics: Animals; Basophils; Blood Platelets; Humans; Hypersensitivity; Inflammation; Lysophosphatidylcholines; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Rabbits | 1981 |
Blood vessels and the new mediators of inflammation.
Topics: Animals; Blood Platelets; Blood Vessels; Capillary Permeability; Humans; Inflammation; Lysophosphatidylcholines; Platelet Activating Factor; Rabbits | 1982 |
Platelet-tissue interaction: role of platelet-activating factor (PAF-acether).
Topics: Anaphylaxis; Animals; Antigen-Antibody Complex; Blood Platelets; Bronchi; Capillary Permeability; Inflammation; Lysophosphatidylcholines; Macrophages; Mice; Platelet Activating Factor; Platelet Aggregation; Rabbits | 1980 |
Platelet-activating factor acether (PAF-acether) involvement in acute inflammatory and pain processes.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Drug Interactions; Edema; Inflammation; Lysophosphatidylcholines; Pain; Platelet Activating Factor; Prostaglandins; Rats; Time Factors | 1981 |
Histamine induces leukocyte rolling in post-capillary venules. A P-selectin-mediated event.
Topics: Animals; Antigens, CD; CD18 Antigens; Cell Adhesion; Cromolyn Sodium; Histamine; Inflammation; Leukocytes; Male; Mast Cells; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Time Factors; Venules | 1994 |
Postinjury neutrophil priming and activation: an early vulnerable window.
Topics: Adolescent; Adult; Female; Humans; Inflammation; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides; Time Factors; Wounds and Injuries | 1995 |
Investigations on the role of inflammatory and anti-inflammatory agents on the treatment of murine B cell leukemia by recombinant human interleukin-2.
Topics: Animals; Anti-Inflammatory Agents; Bradykinin; Dinoprostone; Freund's Adjuvant; Histamine; Inflammation; Interleukin-2; Leukemia, B-Cell; Lipopolysaccharides; Mice; Mice, Inbred BALB C; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Recombinant Proteins; Substance P | 1993 |
Characterization of the increase in vascular permeability induced by vascular permeability factor in vivo.
Topics: Animals; Aprotinin; Bradykinin; Capillary Permeability; Dinoprostone; Endothelial Growth Factors; Heparin; Histamine Antagonists; Humans; In Vitro Techniques; Inflammation; Iodine Radioisotopes; Lymphokines; Male; Neutrophils; Platelet Activating Factor; Rabbits; Recombinant Proteins; Skin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 1993 |
Inflammatory roles of P-selectin.
Topics: Antigens, CD; Calcium; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cell Membrane; Cells, Cultured; Endothelium, Vascular; Humans; Inflammation; Microscopy, Electron, Scanning; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thrombin; Umbilical Veins; Up-Regulation | 1993 |
Stimulation of angiogenesis by substance P and interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Indomethacin; Inflammation; Interleukin-1; Male; Neovascularization, Pathologic; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Prostaglandins; Rats; Rats, Wistar; Receptors, Interleukin-1; Receptors, Neurokinin-1; Regional Blood Flow; Substance P; Xenon Radioisotopes | 1993 |
Inflammation. A signal terminator.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Inflammation; Phospholipases A; Platelet Activating Factor; Rats; Recombinant Proteins | 1995 |
Interleukin-1-induced leukocyte extravasation across rat mesenteric microvessels is mediated by platelet-activating factor.
Topics: Animals; Azepines; Cell Adhesion; Chemotaxis, Leukocyte; Dihydropyridines; Edema; Imidazoles; Inflammation; Interleukin-1; Leukocytes; Male; Mesentery; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins; Skin; Triazoles | 1995 |
Leukotriene-deficient mice generated by targeted disruption of the 5-lipoxygenase gene.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bone Marrow Cells; Carrageenan; Dinoprostone; Female; Inflammation; Leukotriene C4; Leukotrienes; Macrophages; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Phagocytosis; Phenotype; Platelet Activating Factor; Spleen; Tetradecanoylphorbol Acetate | 1995 |
Inflammatory membrane-derived lipids and their antagonists.
Topics: Animals; Humans; Inflammation; Membrane Lipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1994 |
Negative feedback neuroendocrine control of the inflammatory response in rats.
Topics: Adrenal Glands; Afferent Pathways; Animals; Arthritis, Experimental; Bradykinin; Electric Stimulation; Feedback; Freund's Adjuvant; Hindlimb; Hypophysectomy; Hypothalamus; Inflammation; Joints; Male; Metyrapone; Models, Biological; Neurosecretory Systems; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sympathectomy; Sympathetic Nervous System | 1995 |
Altered inflammatory responses in leukotriene-deficient mice.
Topics: Anaphylaxis; Animals; Arachidonate 5-Lipoxygenase; Chemotaxis, Leukocyte; Dinoprostone; Edema; Inflammation; Leukotriene C4; Leukotrienes; Macrophages; Mice; Mice, Knockout; Neutrophils; Platelet Activating Factor; Thromboxane B2 | 1994 |
Distinct biochemical responses of hepatic macrophages and endothelial cells to platelet-activating factor during endotoxemia.
Topics: Acute Disease; Animals; Calcium; Endothelium; Endotoxins; Hydrogen-Ion Concentration; Inflammation; Liver; Macrophage Activation; Macrophages; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Toxemia | 1995 |
In vitro and in vivo impact of a new glycosphingolipid on neutrophils.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Calcimycin; Cell Adhesion; Chemotaxis, Leukocyte; Eicosanoids; Erythrocytes; Gangliosides; Hemolysis; Humans; In Vitro Techniques; Inflammation; Leukocyte Count; Mice; Neutrophils; Phagocytosis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Superoxides | 1994 |
Studies on the mechanisms involved in the inflammatory response in a reversed passive Arthus reaction in guinea-pig skin: contribution of neutrophils and endogenous mediators.
Topics: Animals; Anti-Inflammatory Agents; Arthus Reaction; CD18 Antigens; Edema; Guinea Pigs; Histamine H1 Antagonists; Indium Radioisotopes; Inflammation; Inflammation Mediators; Leukocytes; Lipoxygenase Inhibitors; Neutrophils; Nitric Oxide; Platelet Activating Factor; Rabbits; Skin; Zymosan | 1994 |
Anti-inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor.
Topics: Albuterol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Bronchial Hyperreactivity; Bronchial Spasm; Bronchodilator Agents; Capillary Permeability; Guinea Pigs; Hemodynamics; Histamine; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Platelet Activating Factor; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram | 1994 |
Effects of ZCR-2060 on allergic airway inflammation and cell activation in guinea-pigs.
Topics: Animals; Benzoates; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Inflammation; Leukotriene B4; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperidines; Platelet Activating Factor; Respiratory Hypersensitivity; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Capillary filtration during acute inflammation: role of adherent neutrophils.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Capillaries; CD11 Antigens; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Filtration; Inflammation; Leukotriene B4; Male; Muscle, Smooth, Vascular; Neutrophils; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Receptors, Leukocyte-Adhesion; Splanchnic Circulation | 1993 |
Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene.
Topics: Anaphylaxis; Animals; Arachidonate 5-Lipoxygenase; Base Sequence; Female; Inflammation; Leukotrienes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Molecular Sequence Data; Platelet Activating Factor; Shock; Shock, Septic | 1994 |
Virus-induced airway hyperresponsiveness in the guinea-pig: possible involvement of histamine and inflammatory cells.
Topics: Aerosols; Albumins; Animals; Bronchial Hyperreactivity; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Inflammation; Luminescent Measurements; Lung; Male; Parainfluenza Virus 3, Human; Paramyxoviridae Infections; Platelet Activating Factor; Therapeutic Irrigation; Trachea | 1993 |
Leukocytes and the inflammatory response.
Topics: Adhesiveness; Age Factors; Animals; Antibodies, Monoclonal; Antigens, CD; CD11 Antigens; CD18 Antigens; Cell Adhesion Molecules; Cell Movement; Disease Models, Animal; Endothelium; Humans; Infant, Newborn; Inflammation; Interleukin-8; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Receptors, Leukocyte-Adhesion; Reperfusion Injury; Respiratory Distress Syndrome | 1993 |
Hyperacute rejection in an ex vivo model of renal xenografting. Role of the mediator response and its pharmacologic manipulation by the specific platelet-activating factor antagonist WEB 2086BS.
Topics: Adult; Animals; Antibodies, Heterophile; Antibody Formation; Azepines; Female; Graft Rejection; Hematocrit; Hemoglobins; Humans; Inflammation; Kidney; Kidney Transplantation; Male; Perfusion; Platelet Activating Factor; Pressure; Prostaglandins; Swine; Transplantation, Heterologous; Triazoles; Tumor Necrosis Factor-alpha; Vascular Resistance | 1994 |
Central neurogenic antiinflammatory action of alpha-MSH: modulation of peripheral inflammation induced by cytokines and other mediators of inflammation.
Topics: alpha-MSH; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Edema; Female; Inflammation; Injections, Intraventricular; Interleukin-1; Interleukin-8; Leukotriene B4; Mice; Mice, Inbred BALB C; Platelet Activating Factor | 1994 |
Inflammatory effects of ozone in the upper airways of subjects with asthma.
Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Inflammation; Interleukin-8; Leukocyte Count; Leukotriene B4; Male; Nasal Lavage Fluid; Ozone; Platelet Activating Factor; Respiratory Mechanics; Respiratory System | 1994 |
Inhibitory effects of azelastine hydrochloride on Ca2+ influx, actin polymerization and release of eosinophil cationic protein of an eosinophilic leukaemia cell line EoL-1.
Topics: Actins; Blood Proteins; Bucladesine; Calcimycin; Calcium-Transporting ATPases; Cell Differentiation; Culture Media; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Eosinophils; Humans; Hypersensitivity; Immunoglobulin G; Inflammation; Leukemia, Eosinophilic, Acute; Leukemia, T-Cell; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Phthalazines; Platelet Activating Factor; Polymers; Ribonucleases; Tumor Cells, Cultured | 1993 |
Further substantiation of a significant role for the sympathetic nervous system in inflammation.
Topics: Animals; Arthritis; Bradykinin; Exudates and Transudates; Inflammation; Knee Joint; Lidocaine; Male; Norepinephrine; Oxidopamine; Platelet Activating Factor; Potassium; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Sympathetic Fibers, Postganglionic; Sympathetic Nervous System | 1993 |
PAF-releasing factor in human serum and inflammatory exudate.
Topics: Carrier Proteins; Cholesterol Esters; Exudates and Transudates; Fatty Acids; Humans; Inflammation; Neutrophils; Phosphatidylcholines; Platelet Activating Factor; Triglycerides | 1993 |
Role of PAF in the allergic pleurisy caused by ovalbumin in actively sensitized rats.
Topics: Analysis of Variance; Animals; Azepines; Chemotactic Factors, Eosinophil; Diterpenes; Drug Hypersensitivity; Eosinophils; Female; Freund's Adjuvant; Ginkgolides; Inflammation; Lactones; Leukocyte Count; Male; Oligopeptides; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles | 1993 |
A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo.
Topics: Animals; Antibodies, Monoclonal; Edema; Eosinophils; Guinea Pigs; Inflammation; Leukotriene B4; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Receptors, Very Late Antigen; Zymosan | 1993 |
Interaction of mesangial cells with IgA and IgG immune complexes: a possible mechanism of glomerular injury in IgA nephropathy.
Topics: Antigen-Antibody Complex; Dinoprostone; Glomerular Mesangium; Glomerulonephritis, IGA; Humans; Immunoglobulin A; Immunoglobulin G; Inflammation; Myeloma Proteins; Platelet Activating Factor; Receptors, Fc; Receptors, Immunologic; Superoxides; Tumor Necrosis Factor-alpha | 1993 |
Platelet activating factor, an endogenous mediator of inflammation, induces phenotypic transformation of rat embryo cells.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Embryo, Mammalian; Inflammation; Phenotype; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1993 |
Effects of human neutrophil elastase (HNE) on neutrophil function in vitro and in inflamed microvessels.
Topics: Animals; Cell Adhesion; Cephalosporins; Chemotaxis, Leukocyte; Endothelium, Vascular; Humans; Inflammation; Leukocyte Elastase; Male; Microcirculation; Neutrophils; Pancreatic Elastase; Platelet Activating Factor; Pyrrolidines; Rats; Rats, Wistar; Splanchnic Circulation; Superoxides; Tetradecanoylphorbol Acetate; Umbilical Veins; Venules | 1993 |
An in vitro method for assessing the effects of pro-inflammatory and anti-inflammatory compounds on microvascular permeability in the rat small intestine.
Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Carbon; Diterpenes; Drug Evaluation, Preclinical; Ginkgolides; In Vitro Techniques; Inflammation; Intestine, Small; Lactones; Male; Perfusion; Plant Extracts; Platelet Activating Factor; Rats; Rats, Sprague-Dawley | 1993 |
Increased release of tumor necrosis factor-alpha into the cerebrospinal fluid and peripheral circulation of aged rats.
Topics: Aging; Animals; Cerebrovascular Disorders; Endothelium, Vascular; Inflammation; Injections, Intraventricular; Lipopolysaccharides; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1993 |
Inhibition of nitric oxide synthase attenuates primed microvascular permeability in the in vivo microcirculation.
Topics: Animals; Arginine; Capillary Permeability; Cheek; Cricetinae; Cromolyn Sodium; Dextrans; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Histamine; Inflammation; Macrophage-1 Antigen; Male; Mast Cells; Mesocricetus; Microcirculation; Microscopy, Video; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor | 1995 |
Interleukin-6 delays neutrophil apoptosis via a mechanism involving platelet-activating factor.
Topics: Apoptosis; Humans; Inflammation; Interleukin-6; Neutrophils; Platelet Activating Factor | 1996 |
Phagocytic activation induces formation of platelet-activating factor in human monocyte-derived macrophages and in macrophage-derived foam cells. Relevance to the inflammatory reaction in atherogenesis.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyltransferases; Arteriosclerosis; Cells, Cultured; Foam Cells; Humans; Inflammation; Lipase; Macrophage Activation; Macrophages; Monocytes; Opsonin Proteins; Phagocytosis; Phospholipases A; Platelet Activating Factor; Zymosan | 1996 |
Genetics reveals importance of platelet activating factor in asthma and possibly other inflammatory states.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Asthma; Humans; Inflammation; Phospholipases A; Platelet Activating Factor | 1996 |
Cellular and topical in vivo inflammatory murine models in the evaluation of inhibitors of phospholipase A2.
Topics: Animals; Anti-Inflammatory Agents; Eicosanoids; Ellagic Acid; Homosteroids; Humans; Inflammation; Macrophages; Male; Mice; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Sesterterpenes; Skin; Synovial Fluid; Terpenes | 1995 |
Sephadex G-200-induced eosinophil infiltration into airways in non-sensitized and sensitized guinea pigs, and responsiveness of the cells to stimuli in vitro.
Topics: Aluminum Hydroxide; Animals; Antigens; Bronchoalveolar Lavage Fluid; Calcimycin; Dextrans; Eosinophils; Gels; Guinea Pigs; Indicators and Reagents; Inflammation; Injections, Intraperitoneal; Injections, Intravenous; Ionophores; Leukocyte Count; Leukotriene B4; Male; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Respiratory System; Superoxides; Thromboxane B2 | 1996 |
Platelet-activating factor is both a modulator of synaptic function and a mediator of cerebral injury and inflammation.
Topics: Animals; Brain; Brain Ischemia; Inflammation; Platelet Activating Factor; Signal Transduction; Synaptic Transmission | 1996 |
Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1.
Topics: Animals; Annexin A1; Anti-Inflammatory Agents; Antibodies; Chemotaxis, Leukocyte; Corticosterone; Dexamethasone; Inflammation; Inflammation Mediators; Interleukin-1; Mice; Neutrophils; Platelet Activating Factor | 1996 |
Inhibition of zymosan-induced air-pouch inflammation by rat seminal vesicle protein and by its spermidine derivative.
Topics: Animals; Dinoprostone; Inflammation; Male; Mice; Platelet Activating Factor; Prostatic Secretory Proteins; Proteins; Rats; Seminal Plasma Proteins; Spermidine; Zymosan | 1996 |
Bronchoconstriction and eosinophil recruitment in guinea pig lungs after platelet activating factor administration.
Topics: Acetylcholine; Airway Resistance; Animals; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cell Count; Dose-Response Relationship, Drug; Eosinophilia; Female; Guinea Pigs; Inflammation; Lung; Lung Compliance; Lymphocyte Count; Macrophages; Male; Neutrophils; Platelet Activating Factor; Respiratory Function Tests | 1997 |
Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses.
Topics: 5-Lipoxygenase-Activating Proteins; Anaphylaxis; Animals; Arachidonic Acid; Carrier Proteins; DNA, Complementary; Edema; Eicosanoids; Hypersensitivity, Delayed; Immunoglobulin E; Inflammation; Macrophages, Peritoneal; Membrane Proteins; Mice; Mice, Knockout; Peritonitis; Peroxidase; Platelet Activating Factor; RNA, Messenger; Transcription, Genetic; Zymosan | 1997 |
Cytokines regulate membrane-bound leukocyte elastase on neutrophils: a novel mechanism for effector activity.
Topics: Humans; Inflammation; Interleukin-8; Ions; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Surface Properties; Tumor Necrosis Factor-alpha; Up-Regulation | 1997 |
Pharmacology of ABT-491, a highly potent platelet-activating factor receptor antagonist.
Topics: Acute Disease; Animals; Blood Platelets; Dose-Response Relationship, Drug; Endotoxemia; Guinea Pigs; Humans; Imidazoles; Indoles; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock | 1997 |
Immunoregulatory effect of substance P in human eosinophil migratory function.
Topics: Adjuvants, Immunologic; Chemotaxis, Leukocyte; Dipeptides; Eosinophils; Humans; Hypersensitivity; In Vitro Techniques; Indoles; Inflammation; Interleukin-5; Male; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Recombinant Proteins; Substance P | 1996 |
Platelet-activating factor stimulates interleukin-6 production by human endothelial cells and synergizes with tumor necrosis factor for enhanced production of granulocyte-macrophage colony stimulating factor.
Topics: Azepines; Drug Synergism; Endothelium, Vascular; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation; Inflammation Mediators; Interleukin-6; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Triazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Effects of MTX and BN52021 on PAF-induced chemotaxis of PMNs and intraepidermal accumulation of inflammatory cells in guinea pigs.
Topics: Animals; Chemotaxis, Leukocyte; Dermatologic Agents; Diterpenes; Drugs, Chinese Herbal; Epidermis; Ginkgolides; Guinea Pigs; Inflammation; Lactones; Methotrexate; Neutrophils; Platelet Activating Factor; Random Allocation | 1996 |
Alpha toxin from Clostridium perfringens induces proinflammatory changes in endothelial cells.
Topics: Animals; Cell Adhesion; Cells, Cultured; Clostridium perfringens; Endothelium, Vascular; Epoprostenol; Humans; Inflammation; Neutrophils; Platelet Activating Factor; Rats; Type C Phospholipases | 1997 |
Low-density lipoprotein receptor knockout mice exhibit exaggerated microvascular responses to inflammatory stimuli.
Topics: Animals; Cell Adhesion; Cell Movement; Inflammation; Leukocytes; Leukotriene B4; Mice; Mice, Knockout; Microcirculation; Muscle, Skeletal; Platelet Activating Factor; Receptors, LDL; Tumor Necrosis Factor-alpha | 1997 |
Leukocyte contribution to parenchymal cell death in an experimental model of inflammation.
Topics: Animals; Cell Death; Chemotaxis, Leukocyte; Endothelium; Inflammation; Male; Mesentery; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rats; Rats, Wistar; Triazines; Xanthine Oxidase | 1997 |
Lipid mediators up-regulate CD11b and prime for concordant superoxide and elastase release in human neutrophils.
Topics: Humans; Inflammation; Leukocyte Elastase; Leukotriene B4; Macrophage-1 Antigen; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Respiratory Burst; Superoxides; Wounds and Injuries | 1997 |
Injurious and protective mechanisms in the gut. Interaction of PAF, phospholipase A2, eicosanoids, and nitric oxide synthase.
Topics: Animals; Eicosanoids; Enzyme Activation; Enzyme Inhibitors; Group II Phospholipases A2; Guanidines; Inflammation; Intestinal Mucosa; Isothiuronium; Leukotriene C4; Male; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1997 |
Attenuation of oxygen free radical formation and tissue injury during experimental inflammation by P-selectin blockade.
Topics: Animals; Antibodies, Monoclonal; Cell Adhesion; Cell Movement; Endothelium, Vascular; Inflammation; Male; Mesentery; Microcirculation; Neutrophils; Oxidative Stress; P-Selectin; Platelet Activating Factor; Propidium; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxides | 1997 |
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
Topics: Apoptosis; Cytokines; Dinoprostone; Humans; Inflammation; Jurkat Cells; Leukotriene C4; Macrophages; Neutrophils; Phagocytosis; Platelet Activating Factor; Solubility; Thromboxane B2; Transforming Growth Factor beta | 1998 |
Inhaled cromoglycate reduces airway neurogenic inflammation via tachykinin antagonism.
Topics: Administration, Inhalation; Animals; Anti-Asthmatic Agents; Capillary Permeability; Cromolyn Sodium; Dose-Response Relationship, Drug; Inflammation; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Specific Pathogen-Free Organisms; Substance P; Tachykinins; Trachea | 1997 |
Mechanisms of cell injury in rat mesentery and cremaster muscle.
Topics: Abdomen; Animals; Cell Adhesion; Endothelium, Vascular; Inflammation; Leukocyte Count; Leukopenia; Mesentery; Muscles; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors | 1998 |
The C-C chemokine receptor CCR3 participates in stimulation of eosinophil arrest on inflammatory endothelium in shear flow.
Topics: Antigens, CD; CD18 Antigens; Cell Adhesion; Chemotaxis, Leukocyte; Endothelium, Vascular; Eosinophils; Humans; Inflammation; Integrin alpha4; Integrins; Intercellular Adhesion Molecule-1; Interferon-gamma; Platelet Activating Factor; Receptors, CCR3; Receptors, Chemokine; Rheology; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Virulence Factors, Bordetella | 1998 |
Bronchoalveolar lavage fluid characteristics of early intermediate and late phases of ARDS. Alterations in leukocytes, proteins, PAF and surfactant components.
Topics: Adolescent; Adult; Aged; Biomarkers; Bronchoalveolar Lavage Fluid; Case-Control Studies; Disease Progression; Female; Humans; Inflammation; Leukocyte Count; Male; Middle Aged; Platelet Activating Factor; Prognosis; Prospective Studies; Proteins; Pulmonary Surfactants; Reproducibility of Results; Respiratory Distress Syndrome; Time Factors | 1998 |
PAF levels in saliva are regulated by inflammatory cells.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Analysis of Variance; Cell-Free System; Centrifugation; Female; Humans; Inflammation; Inflammation Mediators; Male; Middle Aged; Periodontitis; Phospholipases A; Platelet Activating Factor; Radioimmunoassay; Saliva; Toothbrushing | 1998 |
Altered expression of CD11b and CD62L after cross-linking of CD45 isoforms on human eosinophils.
Topics: Antibodies, Monoclonal; Cross-Linking Reagents; Eosinophils; Humans; Hypersensitivity; In Vitro Techniques; Inflammation; L-Selectin; Leukocyte Common Antigens; Macrophage-1 Antigen; Platelet Activating Factor; Signal Transduction | 1998 |
Antiinflammatory activity of the platelet-activating factor receptor antagonist A-85783.
Topics: Animals; Anti-Inflammatory Agents; Ear; Indoles; Inflammation; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Skin; Thiazoles | 1998 |
In vivo stimulation of 12(S)-lipoxygenase in the rat skin by bradykinin and platelet activating factor: formation of 12(S)-HETE and hepoxilins, and actions on vascular permeability.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Arachidonate 12-Lipoxygenase; Bradykinin; Capillary Permeability; Enzyme Activation; Inflammation; Inflammation Mediators; Male; Platelet Activating Factor; Rats; Rats, Wistar; Skin | 1999 |
Identification and pharmacological characterization of platelet-activating factor and related 1-palmitoyl species in human inflammatory blistering diseases.
Topics: Animals; Binding, Competitive; Blister; Blotting, Northern; Calcimycin; Calcium; Dose-Response Relationship, Drug; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycerylphosphorylcholine; Humans; Inflammation; KB Cells; Pemphigoid, Bullous; Phosphatidylcholines; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Wistar; Retroviridae; Time Factors; Transduction, Genetic | 1998 |
Characterization of the integrin and activation steps mediating human eosinophil and neutrophil adhesion to chronically inflamed airway endothelium.
Topics: CD11 Antigens; CD18 Antigens; Cell Adhesion; Endothelium; Eosinophils; Epithelium; Granulocyte-Macrophage Colony-Stimulating Factor; GTP-Binding Proteins; Humans; Inflammation; Integrins; Interleukin-3; Interleukin-5; Interleukin-8; Nasal Polyps; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Receptors, CCR3; Receptors, Chemokine; Virulence Factors, Bordetella | 1999 |
Modulation of mast cell activity by a peptide agonist of the thrombin receptor: role of nitric oxide.
Topics: Animals; Calcimycin; Inflammation; Mast Cells; Nitric Oxide; Peptide Fragments; Peritoneum; Platelet Activating Factor; Rats; Receptors, Thrombin; Thrombin | 1999 |
Atherosclerosis and inflammation. Patterns of cytokine regulation in patients with peripheral arterial disease.
Topics: Acute-Phase Proteins; Aged; Aged, 80 and over; Arteriosclerosis; CD11 Antigens; Cytokines; Exercise Test; Female; Humans; Inflammation; Inflammation Mediators; Interleukin-1; Interleukin-6; Leukocyte Count; Leukocyte Elastase; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Activating Factor; Receptors, Cytokine; Superoxides; Tumor Necrosis Factor-alpha | 1999 |
The effects of free oxygen radical scavenger and platelet-activating factor antagonist agents in experimental acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Ceruletide; Deferoxamine; Disease Models, Animal; Edema; Free Radical Scavengers; Ginkgo biloba; Inflammation; Leukocytes; Luminescent Measurements; Male; Mice; Pancreas; Pancreatitis; Phytotherapy; Plants, Medicinal; Platelet Activating Factor | 1999 |
Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1.
Topics: Angiopoietin-1; Animals; Arterioles; Binding Sites; Capillaries; Capillary Permeability; Ear; Endothelial Growth Factors; Endothelium, Vascular; Inflammation; Inflammation Mediators; Lymphokines; Membrane Glycoproteins; Mice; Mice, Transgenic; Microcirculation; Mustard Plant; Neovascularization, Physiologic; Plant Extracts; Plant Lectins; Plant Oils; Plants, Medicinal; Platelet Activating Factor; Ricin; Serotonin; Skin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Venules | 1999 |
Adenosine triphosphate-induced oxygen radical production and CD11b up-regulation: Ca(++) mobilization and actin reorganization in human eosinophils.
Topics: Actin Cytoskeleton; Actins; Adenosine Triphosphate; Calcium Signaling; Chemokine CCL11; Chemokines, CC; Complement C5a; Cytokines; Egtazic Acid; Eosinophils; Flow Cytometry; Free Radicals; Fura-2; Humans; Inflammation; Macrophage-1 Antigen; Pertussis Toxin; Platelet Activating Factor; Reactive Oxygen Species; Receptors, Purinergic P2; Respiratory Burst; Thionucleotides; Up-Regulation; Virulence Factors, Bordetella | 2000 |
Mechanisms of the proinflammatory response of endothelial cells to Candida albicans infection.
Topics: Candida albicans; Endothelium, Vascular; Humans; Inflammation; Interleukin-1; Platelet Activating Factor; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2000 |
Integrin alpha(2)beta(1) (VLA-2) is a principal receptor used by neutrophils for locomotion in extravascular tissue.
Topics: Adult; Animals; Antibodies, Monoclonal; Blister; Cell Adhesion; Chemotactic Factors; Chemotaxis, Leukocyte; Collagen; Gelatin; Gels; Humans; Inflammation; Integrin beta1; Integrins; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Microscopy, Video; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Wistar; Receptors, Collagen | 2000 |
Association among filamentous actin content, CD11b expression, and membrane deformability in stimulated and unstimulated bovine neutrophils.
Topics: Actins; Animals; Blood; Cattle; Cell Membrane; Exotoxins; Inflammation; Interleukin-8; Lipopolysaccharides; Macrophage-1 Antigen; Male; Mannheimia haemolytica; Neutrophils; Platelet Activating Factor; Tumor Necrosis Factor-alpha; Zymosan | 2000 |
Interactions of pro-inflammatory and vasoactive mediators with nitric oxide in the regulation of rat vascular permeability during laparotomy.
Topics: Albumins; Animals; Capillary Permeability; Enzyme Inhibitors; Inflammation; Laparotomy; Leukotrienes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Platelet Activating Factor; Rats; Rats, Wistar; Thromboxanes | 2000 |
Capsaicin inhibits platelet-activating factor-induced cytosolic Ca2+ rise and superoxide production.
Topics: Apoptosis; Biological Transport; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Capsaicin; Cytosol; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Inflammation; Platelet Activating Factor; Superoxides; Thapsigargin; Type C Phospholipases; Up-Regulation | 2000 |
L-selectin facilitates emigration and extravascular locomotion of leukocytes during acute inflammatory responses in vivo.
Topics: Acute Disease; Animals; Cell Adhesion; Cell Movement; Chemokine CXCL1; Chemokines; Chemokines, CXC; Chemotaxis, Leukocyte; Cytokines; In Vitro Techniques; Inflammation; L-Selectin; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Video; Muscle, Skeletal; Perfusion; Platelet Activating Factor | 2000 |
Inhibition of neutrophil L-selectin shedding: a potential anti-inflammatory effect of aprotinin.
Topics: Aprotinin; Cardiopulmonary Bypass; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Inflammation; L-Selectin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Serine Proteinase Inhibitors | 2000 |
Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver.
Topics: Animals; Carbon Tetrachloride; Cell Line; Chromatography, High Pressure Liquid; Diterpenes; Fluorescent Dyes; Free Radical Scavengers; Free Radicals; Fura-2; Ginkgolides; Humans; Inflammation; Inflammation Mediators; Lactones; Lipoproteins, LDL; Liver; Oxidation-Reduction; Phosphatidylcholines; Phospholipases A; Phospholipases A1; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins | 2001 |
Blood transfusion and the two-insult model of post-injury multiple organ failure.
Topics: Blood Preservation; Cell Adhesion; Cells, Cultured; Chemotaxis, Leukocyte; Drug Synergism; Endothelium, Vascular; Fibrinogen; Humans; Inflammation; Lysophosphatidylcholines; Models, Biological; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidative Stress; Platelet Activating Factor; Risk; Superoxides; Transfusion Reaction | 2001 |
BMS-229724 is a tight-binding inhibitor of cytosolic phospholipase A2 that acts at the lipid/water interface and possesses anti-inflammatory activity in skin inflammation models.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Carcinogens; Chlorobenzenes; Dinoprostone; Dose-Response Relationship, Drug; Erythema; Female; Guinea Pigs; Humans; Inflammation; Leukotriene B4; Male; Mice; Neutrophils; Phorbol Esters; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Skin; Sulfones | 2001 |
Lysophosphatidylcholine and lyso-PAF display PAF-like activity derived from contaminating phospholipids.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Calcium; Drug Contamination; Fluorescence; Humans; Hydrolysis; Inflammation; Lysophosphatidylcholines; Mice; Phospholipases A; Phospholipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins; Transfection | 2001 |
Differential inhibition of inflammatory effector functions by petasin, isopetasin and neopetasin in human eosinophils.
Topics: Active Transport, Cell Nucleus; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Calcium; Cell Nucleus; Cells, Cultured; Complement C5a; Cysteine; Cytoplasm; Enzyme Inhibitors; Eosinophil Granule Proteins; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Ribonucleases; Sesquiterpenes | 2001 |
Promotion of platelet aggregation by sera from brucellosis patients with antiphosphatidylcholine antibodies.
Topics: Antibodies, Bacterial; Antibody Specificity; Brucella; Brucellosis; Humans; Inflammation; Phosphatidylcholines; Platelet Activating Factor; Platelet Aggregation | 2001 |
The macrophage response to endotoxin requires platelet activating factor.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Base Sequence; Cells, Cultured; Endotoxins; In Vitro Techniques; Inflammation; Macrophages, Alveolar; Male; Mitogen-Activated Protein Kinases; Molecular Sequence Data; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Platelet Activating Factor; Rabbits; Recombinant Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha | 2002 |
Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock.
Topics: Animals; Blood Pressure; Endopeptidases; Esters; Gabexate; Guanidines; Humans; In Vitro Techniques; Inflammation; Intestinal Mucosa; Intestines; Leukocytes; Male; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phospholipases A; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion; Serine Endopeptidases; Serine Proteinase Inhibitors; Shock; Splanchnic Circulation; Survival Rate | 2002 |
Monocyte chemoattractant protein-1 and 5-lipoxygenase products recruit leukocytes in response to platelet-activating factor-like lipids in oxidized low-density lipoprotein.
Topics: Animals; Arachidonate 5-Lipoxygenase; Cell Movement; Chemokine CCL2; Chemokines; Disease Models, Animal; Diterpenes; Eosinophils; Ginkgolides; Humans; Inflammation; Lactones; Leukocytes; Lipoproteins, LDL; Mice; Neutrophils; Phospholipids; Platelet Activating Factor; Pleural Effusion; Pleurisy; RNA, Messenger | 2002 |
Platelet-activating factor induces cell death in cultured astrocytes and oligodendrocytes: involvement of caspase-3.
Topics: Animals; Animals, Newborn; Antigens, Differentiation; Astrocytes; Azepines; Caspase 3; Caspases; Cell Death; Cells, Cultured; Central Nervous System; Diterpenes; Dose-Response Relationship, Drug; Free Radical Scavengers; Ginkgolides; Glial Fibrillary Acidic Protein; Inflammation; Lactones; Mice; Mice, Inbred CBA; Oligodendroglia; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Spinal Cord Injuries; Triazoles | 2002 |
Postischemic renal oxidative stress induces inflammatory response through PAF and oxidized phospholipids. Prevention by antioxidant treatment.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Ascorbic Acid; Creatinine; Deoxyguanosine; DNA Damage; Inflammation; Ischemia; Kidney; Lipoproteins, LDL; Oxidative Stress; Platelet Activating Factor; Rabbits; Rats | 2002 |
Effect of extracellular matrix proteins on platelet-activating factor-induced eosinophil chemotaxis.
Topics: Animals; Antibodies, Monoclonal; Cattle; CD18 Antigens; Chemotaxis, Leukocyte; Collagen Type IV; Eosinophils; Extracellular Matrix Proteins; Fibronectins; Humans; Hyaluronic Acid; Hypersensitivity; In Vitro Techniques; Inflammation; Laminin; Platelet Activating Factor; Serum Albumin, Bovine; Vitronectin | 2002 |
Differing roles for platelet-activating factor during inflammation of the lung and subarachnoid space. The special case of Streptococcus pneumoniae.
Topics: Animals; Brain; Cell Degranulation; Inflammation; Lipopolysaccharides; Lung; Meningitis, Pneumococcal; Neutralization Tests; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Pneumonia, Pneumococcal; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Streptococcus pneumoniae; Subarachnoid Space; Teichoic Acids | 1992 |
Platelet-activating factor in inflammation and pulmonary disorders.
Topics: Humans; Inflammation; Lung; Lung Diseases; Platelet Activating Factor | 1992 |
Comparative effects of tetrandrine and berbamine on subcutaneous air pouch inflammation induced by interleukin-1, tumour necrosis factor and platelet-activating factor.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Inflammation; Interleukin-1; Male; Platelet Activating Factor; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1992 |
Stimulation of PAF-synthesis in pulmonary artery endothelial cells by Staphylococcus aureus alpha-toxin.
Topics: Adenosine Triphosphate; Animals; Bacterial Toxins; Calcimycin; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemolysin Proteins; Inflammation; Platelet Activating Factor; Pulmonary Artery; Staphylococcus aureus; Swine | 1992 |
Effects of neutrophil depletion and repletion on PAF-induced hyperresponsiveness of canine trachea.
Topics: Animals; Capillary Permeability; Dogs; Female; Inflammation; Leukocytes; Male; Muscle Contraction; Muscle, Smooth; Neutrophils; Parasympathetic Nervous System; Platelet Activating Factor; Trachea | 1992 |
Effects of inflammatory mediators on canine airway neuromuscular function.
Topics: Acetylcholine; Animals; Bronchoconstrictor Agents; Dogs; Electrophysiology; Histamine; In Vitro Techniques; Inflammation; Leukotrienes; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Parasympathomimetics; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Respiratory System | 1992 |
Time course of various inflammatory mediators during recurrent endotoxemia.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Inflammation; Interleukin-6; Lipopolysaccharides; Platelet Activating Factor; Pulmonary Wedge Pressure; Shock, Septic; Swine; Thromboxane B2; Time Factors; Tumor Necrosis Factor-alpha | 1992 |
Effect of dietary alpha-linolenate on platelet-activating factor production in rat peritoneal polymorphonuclear leukocytes.
Topics: alpha-Linolenic Acid; Animals; Calcimycin; Dietary Fats, Unsaturated; Inflammation; Leukotriene B4; Linolenic Acids; Male; Neutrophils; Phosphatidylcholines; Phosphatidylethanolamines; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Inbred Strains | 1991 |
Eosinophil activation on biologic surfaces. Production of O2- in response to physiologic soluble stimuli is differentially modulated by extracellular matrix components and endothelial cells.
Topics: Endothelium, Vascular; Eosinophils; Extracellular Matrix; Humans; In Vitro Techniques; Inflammation; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Substance P; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
A role of peripheral leukocytes in vascular permeability and edema formation in air pouch type allergic inflammation in rats.
Topics: Animals; Capillary Permeability; Chemotaxis, Leukocyte; Cyclophosphamide; Dinoprostone; Edema; Hypersensitivity; In Vitro Techniques; Inflammation; Leukocyte Count; Leukocytes; Male; Neutrophils; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serotonin; SRS-A | 1991 |
Platelet activating factor as a proinflammatory mediator in acetic-induced colitis in the rat.
Topics: Acetates; Animals; Azepines; Colitis; Inflammation; Platelet Activating Factor; Polyunsaturated Alkamides; Pyridines; Rats; Rats, Inbred Strains; Triazoles | 1991 |
Involvement of platelet-activating factor in zymosan-induced rat pleurisy.
Topics: Animals; Cyproheptadine; Eosinophils; Inflammation; Leukocytes; Male; Mast Cells; Neutrophils; Platelet Activating Factor; Pleurisy; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Zymosan | 1991 |
Molecular biology. Inflammatory activities.
Topics: Animals; Cloning, Molecular; GTP-Binding Proteins; Guinea Pigs; Humans; Inflammation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1991 |
[PAF synthesis and its regulation].
Topics: Acetyltransferases; Animals; Arachidonic Acid; Arachidonic Acids; Diacylglycerol Cholinephosphotransferase; Inflammation; Kidney; Macrophages; Neutrophils; Platelet Activating Factor; Spleen | 1991 |
Time-dependent synergistic interactions between the vasodilator neuropeptide, calcitonin gene-related peptide (CGRP) and mediators of inflammation.
Topics: Animals; Calcitonin Gene-Related Peptide; Complement C5a; Drug Synergism; Epoprostenol; In Vitro Techniques; Indium Radioisotopes; Inflammation; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Time Factors; Zymosan | 1991 |
The inflammatory actions of platelet activating factor are blocked by levorotatory terbutaline.
Topics: Animals; Blood Pressure; Bradykinin; Dogs; Edema; Histamine; Inflammation; Injections, Intra-Arterial; Lymph; Lymphatic System; Molecular Conformation; Platelet Activating Factor; Receptors, Adrenergic, beta; Terbutaline | 1990 |
Cooperation between tumor necrosis factor (TNF) and platelet-activating factor (PAF) in the inflammatory response.
Topics: Animals; Arthritis; Diterpenes; Drug Synergism; Ginkgolides; Humans; In Vitro Techniques; Inflammation; Lactones; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides; Tumor Necrosis Factor-alpha | 1990 |
Effect of inflammatory mediators on airway nerves and muscle.
Topics: Acetylcholine; Animals; Bronchoconstriction; Dogs; Humans; In Vitro Techniques; Inflammation; Leukotrienes; Muscle Contraction; Muscle, Smooth; Ozone; Platelet Activating Factor; Prostaglandins; Respiratory System; Thromboxanes; Trachea | 1991 |
Synthesis of platelet activating factor by ocular tissue from inflamed eyes.
Topics: Animals; Calcimycin; Chromatography, High Pressure Liquid; Ciliary Body; Cornea; Endotoxins; Eye; Female; Inflammation; Iris; Male; Platelet Activating Factor; Platelet Aggregation; Rabbits; Retina | 1991 |
[PAF and diseases].
Topics: Animals; Female; Humans; Inflammation; Ischemia; Nephritis; Platelet Activating Factor; Pregnancy; Shock, Septic; Stomach Ulcer | 1991 |
Possible role for platelet-activating factor in neutrophil infiltration in allergic inflammation in rats.
Topics: Animals; Benzoquinones; Furans; Hypersensitivity; Immunization; Inflammation; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1990 |
Hirudin-based peptides block the inflammatory effects of thrombin on endothelial cells.
Topics: Calcimycin; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Hirudins; Humans; Inflammation; Kinetics; Peptide Fragments; Platelet Activating Factor; Thrombin | 1990 |
Amplification of platelet response during acute inflammation in rats.
Topics: Acute Disease; Animals; Egtazic Acid; Gallic Acid; Heparin; Inflammation; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Aggregation; Platelet Factor 4; Rats | 1990 |
Tumor necrosis factor primes the effects of platelet-activating factor on rat vascular permeability.
Topics: Animals; Capillary Permeability; Drug Synergism; Inflammation; Interleukin-1; Male; Organ Specificity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 1990 |
An anti-inflammatory protein secreted from the rat seminal vesicle epithelium inhibits the synthesis of platelet-activating factor and the release of arachidonic acid and prostacyclin.
Topics: Acetyltransferases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Epoprostenol; Humans; Inflammation; Macrophages; Male; Neutrophils; Platelet Activating Factor; Proteins; Rats; Rats, Inbred Lew; Recombinant Proteins; Seminal Vesicles; Thrombin; Tumor Necrosis Factor-alpha | 1990 |
A factor in serum lowers resistance and opens tight junctions of MDCK cells.
Topics: Animals; Azepines; Blood; Cell Line; Chromatography, Gel; Complement C3a; Complement C5a; Culture Media; Dogs; Humans; Inflammation; Intercellular Junctions; Kidney; Kinetics; Molecular Weight; Platelet Activating Factor; Serum Albumin; Triazoles | 1990 |
Inflammatory mediators are involved in the Candida albicans killing activity of human epidermal cells.
Topics: Candida albicans; Dexamethasone; Dinoprostone; Diterpenes; Epidermal Cells; Epidermis; Ginkgolides; Humans; Indomethacin; Inflammation; Interleukin-1; Lactones; Phagocytosis; Platelet Activating Factor; Recombinant Proteins; Ultraviolet Rays | 1990 |
Novel aspect of Crohn's disease: increased content of platelet-activating factor in ileal and colonic mucosa.
Topics: Adolescent; Adult; Aged; Child; Crohn Disease; Humans; Ileum; Inflammation; Intestinal Mucosa; Middle Aged; Platelet Activating Factor | 1990 |
Cooperation between platelets and neutrophils for paf-acether (platelet-activating factor) formation.
Topics: Animals; Blood Platelets; Cell Communication; Female; Humans; Inflammation; L-Lactate Dehydrogenase; Male; Muramidase; Neutrophils; Platelet Activating Factor; Rabbits; Thrombin; Zymosan | 1990 |
Effects of proinflammatory mediators on canine neutrophil chemotaxis and aggregation.
Topics: Analysis of Variance; Animals; Cell Aggregation; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a, des-Arginine; Dogs; Dose-Response Relationship, Drug; Inflammation; Leukotrienes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor | 1990 |
Inflammatory exudates in skin windows induced by 1-0-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine.
Topics: Animals; Exudates and Transudates; Inflammation; Leukocytes; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Skin Window Technique | 1990 |
Inflammatory oedema induced by synergism between calcitonin gene-related peptide (CGRP) and mediators of increased vascular permeability.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Complement C5; Complement C5a, des-Arginine; Dinoprostone; Drug Synergism; Edema; Histamine; Inflammation; Injections, Intradermal; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Platelet Activating Factor; Prostaglandins E; Rabbits; Rats; Rats, Inbred Lew; Skin; Species Specificity; Substance P | 1985 |
Leukotriene B4, platelet-activating factor and substance P as mediators of acute inflammation.
Topics: Acute Disease; Animals; Cheek; Cricetinae; Inflammation; Leukotriene B4; Mesocricetus; Mouth Mucosa; Muscles; Platelet Activating Factor; Rabbits; Substance P | 1987 |
Platelet-activating factor primes neutrophil responses to agonists: role in promoting neutrophil-mediated endothelial damage.
Topics: Benzofurans; Cell Aggregation; Cell Survival; Diterpenes; Endothelium, Vascular; Fetal Hemoglobin; Furans; Ginkgolides; Hemoglobins, Abnormal; Humans; Inflammation; Lactones; Lignans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides | 1988 |
Vasodepression ex vivo after administration of inflammatory mediators in vivo in the rat.
Topics: Alprostadil; Animals; Biological Factors; Bradykinin; Endotoxins; Epoprostenol; Escherichia coli; Female; Histamine; Inflammation; Norepinephrine; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Serotonin; SRS-A; Substance P; Vasoconstriction | 1989 |
The effects of TMB-8 on the shape changes of vascular endothelial cells resulting from exposure to various inflammatory agents.
Topics: Animals; Bradykinin; Calcimycin; Calcium Channel Blockers; Dinoprostone; Endothelium, Vascular; Gallic Acid; Guinea Pigs; Histamine; In Vitro Techniques; Inflammation; Leukotrienes; Platelet Activating Factor; Vena Cava, Inferior | 1989 |
[Contamination of fermented milk products by proinflammatory autacoid paf-acether].
Topics: Dairy Products; Fermentation; Food Contamination; Inflammation; Platelet Activating Factor; Protein Precursors | 1989 |
Pharmacological manipulation of inflammation in rabbit hydronephrosis: effects of a combined cyclooxygenase/lipoxygenase inhibitor ethoxyquin, a thromboxane synthase inhibitor RS-5186 and a PAF antagonist L-659,989.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Ethoxyquin; Fatty Acids, Nonesterified; Furans; Hydronephrosis; Inflammation; Kidney; Leukotriene B4; Lipoxygenase Inhibitors; Male; Perfusion; Platelet Activating Factor; Quinolines; Rabbits; Thiophenes; Thromboxane-A Synthase | 1989 |
Inflammatory mediators and beta-adrenoceptor function.
Topics: Arachidonic Acids; Cyclic AMP; Humans; Inflammation; Leukotriene B4; Lung; Lymphocytes; Platelet Activating Factor; Radioligand Assay; Receptors, Adrenergic, beta; SRS-A | 1989 |
Pharmacological demonstration of inflammatory mediators using experimental inflammatory models: rat pleurisy induced by carrageenin and phorbol myristate acetate.
Topics: Animals; Capillary Permeability; Carrageenan; Disease Models, Animal; Epoprostenol; Guinea Pigs; Inflammation; Kinins; Platelet Activating Factor; Pleurisy; Prostaglandins; Rabbits; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
[Platelet-activating factor producing cell--target cell interactions].
Topics: Animals; Blood Platelets; Cells, Cultured; Inflammation; Neutrophils; Platelet Activating Factor; Platelet Aggregation | 1989 |
Inhibition of eicosanoid and PAF formation by dexamethasone in rat inflammatory polymorphonuclear neutrophils may implicate lipocortin 's'.
Topics: Annexins; Calcimycin; Dexamethasone; Dinoprostone; Glycoproteins; Humans; Inflammation; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1988 |
Effects of serum albumin, indomethacin and histamine H1-antagonists on Paf-acether-induced inflammatory responses in the skin of experimental animals and man.
Topics: Adult; Animals; Blood Proteins; Chlorpheniramine; Guinea Pigs; Histamine H1 Antagonists; Humans; Indomethacin; Inflammation; Male; Platelet Activating Factor; Pyrilamine; Serum Albumin; Skin | 1985 |
Inflammatory mechanisms in the Arthus reaction.
Topics: Animals; Antigen-Antibody Complex; Arthus Reaction; Complement C5; Complement C5a; Dinoprostone; Edema; Histamine H1 Antagonists; Inflammation; Male; Neutrophils; Platelet Activating Factor; Prostaglandins E; Rabbits | 1986 |
Mediators of inflammation and antagonism of experimental pleurisy in the rat by fenspiride.
Topics: Animals; Female; Guinea Pigs; Inflammation; Male; Platelet Activating Factor; Pleurisy; Rats; Rats, Inbred Strains; Spiro Compounds; Zymosan | 1988 |
Background and discovery of lipocortins.
Topics: Animals; Annexins; Anti-Inflammatory Agents; Aspirin; Glucocorticoids; Glycoproteins; Humans; Inflammation; Lung; Macrophages; Phospholipases; Platelet Activating Factor; Prostaglandins; Steroids | 1986 |
Experimental eosinophilia and inflammation--the effect of various inflammatory mediators and chemoattractants.
Topics: Acid Phosphatase; Animals; Arylsulfatases; Blood Proteins; Bradykinin; Carrageenan; Cell Movement; Chemotactic Factors; Chemotactic Factors, Eosinophil; Disease Models, Animal; Eosinophil Granule Proteins; Eosinophilia; Eosinophils; Female; Guinea Pigs; Histamine; Inflammation; Isoenzymes; Male; Neutrophils; Peroxidase; Peroxidases; Platelet Activating Factor; Ribonucleases; Time Factors; Trichinellosis | 1986 |
Phospholipase A2 products induce pulmonary beta-adrenoceptor deviations.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dihydroalprenolol; Guinea Pigs; In Vitro Techniques; Inflammation; Lung; Male; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Receptors, Adrenergic, beta | 1986 |
Stimulated release of neutral proteinases elastase and cathepsin G from inflammatory rat polymorphonuclear leukocytes.
Topics: Animals; Calcimycin; Cathepsin G; Cathepsins; Cytoplasmic Granules; Dose-Response Relationship, Drug; Inflammation; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serine Endopeptidases | 1987 |
Alkylacetylglycerols versus lyso-PAF as precursors in PAF biosynthesis and the role of arachidonic acid in PAF metabolism.
Topics: Acetyltransferases; Animals; Arachidonic Acid; Arachidonic Acids; Glycerides; In Vitro Techniques; Inflammation; Lipids; Platelet Activating Factor; Rabbits | 1986 |
Platelet-activating factor in the inflammatory exudate in the anaphylactic phase of allergic inflammation in rats.
Topics: Adenosine Diphosphate; Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Exudates and Transudates; Inflammation; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Inbred Strains; Thiazoles | 1987 |
Dexamethasone inhibits platelet activating factor-induced inflammation in the paw but not the pleural cavity of rats.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Dexamethasone; Edema; Female; Foot; Indomethacin; Inflammation; Male; Platelet Activating Factor; Pleura; Pyrazoles; Rats; Rats, Inbred Strains | 1988 |
A platelet-activating factor antagonist inhibits interleukin 1-induced inflammation.
Topics: Animals; Aqueous Humor; Capillary Permeability; Dinoprostone; Eye; Female; Flurbiprofen; Inflammation; Interleukin-1; Leukocyte Count; Platelet Activating Factor; Prednisolone; Prostaglandins E; Proteins; Quinolinium Compounds; Rabbits; Recombinant Proteins | 1988 |
Prolongation of pig-to-dog renal xenograft survival by modification of the inflammatory mediator response.
Topics: Alprostadil; Animals; Biopsy; Dogs; Epoprostenol; Female; Graft Survival; Inflammation; Kidney; Kidney Transplantation; Male; Platelet Activating Factor; Platelet Count; Quinolinium Compounds; Renal Circulation; Swine; Transplantation, Heterologous | 1987 |
Inflammatory effects of acetylglycerylether phosphorylcholine: vascular permeability increase and induction of pleurisy in rats.
Topics: Animals; Azo Compounds; Bradykinin; Capillary Permeability; Dexamethasone; Guinea Pigs; Histamine; Indomethacin; Inflammation; Injections; Leukocyte Count; Male; Methysergide; Phospholipid Ethers; Platelet Activating Factor; Pleural Effusion; Pleurisy; Prostaglandins; Pyrilamine; Rabbits; Rats; Rats, Inbred Strains; Serotonin; Skin; Skin Physiological Phenomena; Thiazoles; Trypan Blue | 1986 |
Age-dependent differential development of leukotactic and vasoactive responsiveness to acute inflammatory mediators.
Topics: Aging; Animals; Blood; Bradykinin; Capillary Permeability; Chemotaxis, Leukocyte; Dinoprostone; Female; Histamine; Inflammation; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Prostaglandins E; Rabbits; Zymosan | 1986 |
Thrombin stimulates neutrophil adherence by an endothelial cell-dependent mechanism: characterization of the response and relationship to platelet-activating factor synthesis.
Topics: Blood Coagulation; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium; Extracellular Matrix; Humans; In Vitro Techniques; Inflammation; Microscopy, Electron, Scanning; Muscle, Smooth, Vascular; Neutrophils; Platelet Activating Factor; Thrombin; Time Factors | 1986 |
Interactions between local inflammatory and systemic haematological effects of PAF-acether in the rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Edema; Indomethacin; Inflammation; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombocytopenia | 1987 |
PAF-acether in chronic arthritis.
Topics: Animals; Arthritis; Arthritis, Rheumatoid; Chronic Disease; Disease Models, Animal; Humans; Inflammation; Injections, Intra-Articular; Male; Ovalbumin; Platelet Activating Factor; Rabbits; Synovial Fluid | 1987 |
Desensitization to PAF-induced rat paw oedema by repeated intraplantar injections.
Topics: Animals; Carbamates; Carrageenan; Drug Tolerance; Edema; Inflammation; Injections; Injections, Intravenous; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Evidence favouring PAF rather than leukotrienes in the pathogenesis of asthma.
Topics: Asthma; Bronchi; Eosinophils; Humans; Inflammation; Mucus; Platelet Activating Factor; Respiratory System; SRS-A | 1986 |
Inflammatory characteristics of PAF-acether in the skin of experimental animals and man.
Topics: Animals; Dinoprostone; Humans; Inflammation; Platelet Activating Factor; Prostaglandins E; Skin Tests | 1985 |
Changing concepts on pathogenesis of asthma.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Asthma; Bronchi; Chemotactic Factors; Child; Epithelium; Humans; Inflammation; Macrophages; Mast Cells; Platelet Activating Factor; Pulmonary Alveoli; Vagus Nerve | 1985 |
Biosynthesis of paf-acether: VIII: Impairment of paf-acether production in activated macrophages does not depend upon acetyltransferase activity.
Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Acetyltransferases; Animals; Female; Glycerylphosphorylcholine; Inflammation; Kinetics; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Platelet Activating Factor | 1986 |
Evidence that platelet activating factor may mediate some acute inflammatory responses. Studies with the platelet-activating factor antagonist, CV3988.
Topics: Acute Disease; Animals; Blood Platelets; Capillary Permeability; Cell Movement; Inflammation; Leukocytes; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phospholipid Ethers; Platelet Activating Factor; Rabbits; Regional Blood Flow; Serum Albumin; Skin; Thiazoles; Thrombocytopenia | 1986 |
The effect of glucocorticoids on lyso-PAF formation in vitro and in vivo.
Topics: Animals; Dexamethasone; Exudates and Transudates; Glucocorticoids; Guinea Pigs; In Vitro Techniques; Inflammation; Lung; Macrophages; Platelet Activating Factor; Rats; Time Factors | 1986 |
Inflammatory action of PAF-acether in the rat pleural cavity.
Topics: Animals; Inflammation; Leukocytes; Male; Platelet Activating Factor; Pleurisy; Rats; Rats, Inbred Strains | 1986 |
Properties of PAF-acether appropriate to a mediator of the inflammatory aspects of asthma.
Topics: Asthma; Edema; Eosinophils; Humans; Inflammation; Platelet Activating Factor | 1985 |